The role of Thallium-201 scintigraphy and Tc-99m pentavalent dimercaptosuccinic acid in diagnosis and grading of chondrosarcoma.

Abstract:

PURPOSE:Distinguishing between enchondromas and low-grade (grade 1) chondrosarcomas can be challenging. The aim of this study was to investigate the role of Thallium-201 scintigraphy and Technetium-99 m pentavalent dimercaptosuccinic acid (Tc-99 m DMSA (V)) in the diagnosis and grading of chondrosarcomas. METHODS:232 consecutive patients with pathologically proven cartilaginous tumours between the years 2000 and 2018 were evaluated. We included 197 patients (101 males and 96 females; median age 50 years; range 15-86 years) who underwent Thallium-201(n = 193) and/or Tc-99 m DMSA (V) scanning (n = 67). Increased uptake was defined as uptake greater than background. The reference standard was the histopathological assessment based on a grading system (grade 1-3). Data was analysed using multivariate modelling. RESULTS:There were 46 patients with enchondromas and 151 with chondrosarcomas. Of those, 64 (enchondroma n = 21, chondrosarcoma n = 43) underwent both Thallium-201 and Tc-99 m DMSA (V). Thallium-201 uptake had 7.92 times greater odds of grade 1 chondrosarcomas than enchondromas. Thallium-201 uptake was significantly associated with the odds of a higher grade chondrosarcoma (grade 2-3). DMSA (V) positivity was associated with 4.75 times the odds of a chondrosarcoma diagnosis over enchondroma (p = 0.024). DMSA (V) uptake revealed no association with chondrosarcoma grading. CONCLUSION:Low-grade chondrosarcomas continue to pose a diagnostic dilemma. Thallium-201 scans may identify malignancy in benign appearing tumours as well as differentiate between low-grade and high-grade chondrosarcomas in said malignancies. DMSA (V) may be useful in distinguishing between benign and malignant entities as a whole.

journal_name

Eur J Radiol

authors

Jo O,Schlicht S,Slavin J,Di Bella C,Pang G,Powell G,Spelman T,Choong PF

doi

10.1016/j.ejrad.2020.108846

subject

Has Abstract

pub_date

2020-04-01 00:00:00

pages

108846

eissn

0720-048X

issn

1872-7727

pii

S0720-048X(20)30035-8

journal_volume

125

pub_type

杂志文章
  • Effect of digital edge-enhancement on the visibility of normal parenchymal lung markings.

    abstract::Digital 'conventional-like' (C-L) and edge-enhanced (E-E) posteroanterior chest roentgenograms of 42 healthy individuals were ranked twice (interval of at least 5 days) in the order of increasing lung parenchymal markings (a total of four rankings). This was done by three radiologists, two residents, one medical stude...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/0720-048x(94)90275-5

    authors: Vehmas T,Korhola O,Pölönen P,Knuutila T,Kivisaari A,Holmberg J,Bondestam S,Tikkanen H

    更新日期:1994-05-01 00:00:00

  • T2-enhanced tensor diffusion trace-weighted image in the detection of hyper-acute cerebral infarction: comparison with isotropic diffusion-weighted image.

    abstract:BACKGROUND AND PURPOSE:Although isotropic diffusion-weighted imaging (isoDWI) is very sensitive to the detection of acute ischemic stroke, it may occasionally show diffusion negative result in hyper-acute stroke. We hypothesize that high diffusion contrast diffusion trace-weighted image with enhanced T2 may improve str...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/j.ejrad.2009.04.023

    authors: Chou MC,Tzeng WS,Chung HW,Wang CY,Liu HS,Juan CJ,Lo CP,Hsueh CJ,Chen CY

    更新日期:2010-06-01 00:00:00

  • Malignant pleural mesothelioma: computed tomography and correlation with histology.

    abstract:OBJECTIVE:To review the computed tomography (CT) imaging findings of pleural mesothelioma at presentation and to correlate the CT with the histological subtype. MATERIALS AND METHODS:Pathology reports from 1997 to 2006 were reviewed at two academic institutions to identify patients with proven pleural mesothelioma. Di...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/j.ejrad.2008.02.004

    authors: Seely JM,Nguyen ET,Churg AM,Müller NL

    更新日期:2009-06-01 00:00:00

  • Peritoneal cavity circumference on computed tomography predicts outcomes in acute pancreatitis.

    abstract:OBJECTIVES:We investigated the role of novel intra-abdominal parameters measured by computed tomography (CT) in the prediction of clinical outcomes in acute pancreatitis (AP). METHODS:Patients with AP underwent an abdominal CT scan on admission to define different intra-abdominal parameters (abdominal circumference, p...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/j.ejrad.2020.109327

    authors: Monreal-Robles R,Kohn-Gutiérrez AE,Sordia-Ramírez J,Zúñiga-Segura JA,Palafox-Salinas JA,de la Rosa-Pacheco S,Elizondo-Riojas G,González-González JA

    更新日期:2020-11-01 00:00:00

  • Investigation of renal lesions by diffusion-weighted magnetic resonance imaging applying intravoxel incoherent motion-derived parameters--initial experience.

    abstract:PURPOSE:Usefulness of biexponentially fitted signal attenuation at different b-values for differentiating the histological characteristics of renal tumors. MATERIALS AND METHODS:A total of 26 patients with 28 renal masses (histologically proven: 20 clear cell renal cell carcinomas [ccRCC], three transitional cell carc...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/j.ejrad.2011.10.016

    authors: Rheinheimer S,Stieltjes B,Schneider F,Simon D,Pahernik S,Kauczor HU,Hallscheidt P

    更新日期:2012-03-01 00:00:00

  • Quantitative evaluation of CT-perfusion map as indicator of tumor response to transarterial chemoembolization and radiofrequency ablation in HCC patients.

    abstract:PURPOSE:To assess if radiofrequency ablation (RFA) and transarterial chemoembolization (TACE) may influence the evaluation of perfusion parameters obtained with CT-perfusion (CT-p) in HCC treated patients. MATERIALS AND METHODS:Thirty-three consecutive cirrhotic patients with biopsy-proven diagnosis of HCC lesions and...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/j.ejrad.2014.05.040

    authors: Ippolito D,Fior D,Bonaffini PA,Capraro C,Leni D,Corso R,Sironi S

    更新日期:2014-09-01 00:00:00

  • Quantitative CT detects changes in airway dimensions and air-trapping after bronchial thermoplasty for severe asthma.

    abstract:OBJECTIVES:Bronchial thermoplasty (BT) can be considered in the treatment of severe asthma to reduce airway smooth muscle mass and bronchoconstriction. We hypothesized that BT may thus have long-term effects on airway dimensions and air-trapping detectable by quantitative computed tomography (QCT). METHODS:Paired in- ...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/j.ejrad.2018.08.007

    authors: Konietzke P,Weinheimer O,Wielpütz MO,Wagner WL,Kaukel P,Eberhardt R,Heussel CP,Kauczor HU,Herth FJ,Schuhmann M

    更新日期:2018-10-01 00:00:00

  • MRI features of epidural extramedullary hematopoiesis.

    abstract::A case of beta-thalassemia intermedia with spinal cord compression due to extramedullary hematopoiesis, which was successfully treated by blood transfusion, is presented. Emphasis was made on the MRI appearance of extramedullary hematopoiesis on different pulse sequences. The theories that aimed to explain the involve...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/s0720-048x(99)00122-9

    authors: Alorainy IA,Al-Asmi AR,del Carpio R

    更新日期:2000-07-01 00:00:00

  • The role of dynamic contrast-enhanced and diffusion weighted magnetic resonance imaging in the female pelvis.

    abstract::Functional imaging by means of dynamic multiphase contrast-enhanced magnetic resonance imaging (DCE-MRI) and diffusion weighted magnetic resonance imaging (DW-MRI) is now part of the standard imaging protocols for evaluation of the female pelvis. DCE-MRI and DW-MRI are important MR imaging techniques which enable the ...

    journal_title:European journal of radiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.ejrad.2010.01.026

    authors: Sala E,Rockall A,Rangarajan D,Kubik-Huch RA

    更新日期:2010-12-01 00:00:00

  • Radiation exposure in CT-guided interventions.

    abstract:PURPOSE:To investigate radiation exposure in computed tomography (CT)-guided interventions, to establish reference levels for exposure, and to discuss strategies for dose reduction. MATERIALS AND METHODS:We analyzed 1576 consecutive CT-guided procedures in 1284 patients performed over 4.5 years, including drainage pla...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/j.ejrad.2013.08.035

    authors: Kloeckner R,dos Santos DP,Schneider J,Kara L,Dueber C,Pitton MB

    更新日期:2013-12-01 00:00:00

  • Retrieval of intravascular foreign bodies with goose neck snare.

    abstract:PURPOSE:to evaluate the efficacy and advantages of the snare systems in the retrieval of foreign bodies from vascular system. MATERIALS AND METHODS:the snare technique has been used for intravascular foreign body retrieval. We performed percutaneous extraction of intravascular foreign bodies using combination multipur...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/S0720-048X(03)00078-0

    authors: Koseoglu K,Parildar M,Oran I,Memis A

    更新日期:2004-03-01 00:00:00

  • Imaging of IgG4-related disease in the extracranial head and neck.

    abstract:PURPOSE:Immunoglobulin G4-related disease (IgG4-RD) is a newly defined fibro-inflammatory multisystemic condition defined by a triad of diagnostic criteria based on clinical presentation, biochemical and histopathological findings. Whereas some subsites of this disease have been well described in the literature so far ...

    journal_title:European journal of radiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.ejrad.2021.109560

    authors: Dragan AD,Weller A,Lingam RK

    更新日期:2021-01-27 00:00:00

  • Perineural spread of nasopharyngeal carcinoma: radiological and CT demonstration.

    abstract::Perineural spread is well known to be the most insidious form of tumour spread of a number of head and neck malignancies. However, perineural extension of nasopharyngeal carcinoma (NC) is a poorly recognized event. Four cases of perineural metastases from NC have been detected with pluridirectional tomography and CT. ...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:

    authors: Pandolfo I,Gaeta M,Blandino A,Longo M,Faranda C

    更新日期:1988-11-01 00:00:00

  • Comparison of coronal and axial computed tomography measurements of mediastinal nodes before primary surgery for non-small cell lung cancer.

    abstract:OBJECTIVE:To assess computed tomography (CT) evaluation of mediastinal nodes in non-small cell lung cancer to predict metastatic involvement by measurement of their axis and surface area in the coronal plane, as compared to standard short-axis measures in the axial plane. METHODS:Evaluation of mediastinal nodes was re...

    journal_title:European journal of radiology

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.ejrad.2011.06.015

    authors: Guinet C,Rousset P,Bobbio A,Alifano M,Damotte D,Régnard JF,Buy JN

    更新日期:2012-09-01 00:00:00

  • Percutaneous treatment of benign bile duct strictures.

    abstract:PURPOSE:To evaluate long-term results of treatment of benign bile duct strictures. MATERIALS AND METHODS:From February 1994 to November 2005, 21 patients (9 men, 12 women) with median age of 50.6 years (range 27-77 years) were indicated to percutaneous treatment of benign bile duct stricture. Stricture of hepatic duct...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/j.ejrad.2007.01.032

    authors: Köcher M,Cerná M,Havlík R,Král V,Gryga A,Duda M

    更新日期:2007-05-01 00:00:00

  • Shear wave elastography versus real-time elastography on evaluation thyroid nodules: a preliminary study.

    abstract:OBJECTIVE:To comparatively evaluate shear wave elastography (SWE) and real-time elastography (RTE) in distinguishing malignant from benign thyroid nodules. METHODS:49 patients with 64 focal thyroid nodules were enrolled and underwent SWE and RTE before surgery. SWE elasticity indices (mean, minimum and maximum value o...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/j.ejrad.2014.02.024

    authors: Liu BX,Xie XY,Liang JY,Zheng YL,Huang GL,Zhou LY,Wang Z,Xu M,Lu MD

    更新日期:2014-07-01 00:00:00

  • Diagnostic value of MRI in comparison to scintigraphy, PET, MS-CT and PET/CT for the detection of metastases of bone.

    abstract::The initial localization of metastases in the bone in patients with solid tumors has a relatively good prognosis in comparison with visceral metastasization. The early detection of bone marrow metastases allows for a rapid initiation of therapy and a subsequent reduction in the morbidity rate. Modern MRI is superior t...

    journal_title:European journal of radiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.ejrad.2005.01.016

    authors: Ghanem N,Uhl M,Brink I,Schäfer O,Kelly T,Moser E,Langer M

    更新日期:2005-07-01 00:00:00

  • Utility of USPIO-enhanced MR imaging to identify inflammation and the fibrous cap: a comparison of symptomatic and asymptomatic individuals.

    abstract:BACKGROUND AND PURPOSE:Inflammation is a risk factor the vulnerable atheromatous plaque. This can be detected in vivo on high-resolution magnetic resonance (MR) imaging using a contrast agent, Sinerem, an ultra-small super-paramagnetic iron oxide (USPIO). The aim of this study was to explore whether there is a differen...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/j.ejrad.2008.01.047

    authors: Howarth SP,Tang TY,Trivedi R,Weerakkody R,U-King-Im J,Gaunt ME,Boyle JR,Li ZY,Miller SR,Graves MJ,Gillard JH

    更新日期:2009-06-01 00:00:00

  • Improving image quality in portal venography with spectral CT imaging.

    abstract:OBJECTIVE:To investigate the effect of energy spectral CT on the image quality of CT portal venography in cirrhosis patients. MATERIALS AND METHODS:30 portal hypertension patients underwent spectral CT examination using a single-tube, fast dual tube voltage switching technique. 101 sets of monochromatic images were ge...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/j.ejrad.2011.02.063

    authors: Zhao LQ,He W,Li JY,Chen JH,Wang KY,Tan L

    更新日期:2012-08-01 00:00:00

  • Comparison of diagnostic value of multidetector computed tomography and X-ray in the detection of body packing.

    abstract:OBJECTIVE:Radiologists and other clinicians are facing an increasing number of illegal drug-related medical conditions. We aimed to draw attention to this growing global problem and to highlight some of the important points related to diagnosis and follow-up of body packing. We compare the diagnostic performance of une...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/j.ejrad.2012.12.022

    authors: Bulakci M,Kalelioglu T,Bulakci BB,Kiris A

    更新日期:2013-08-01 00:00:00

  • T2 mapping in patellar chondromalacia.

    abstract:OBJECTIVE:To study the correlation between the T2 relaxation times of the patellar cartilage and morphological MRI findings of chondromalacia. METHODS:This prospective study comprises 50 patients, 27 men and 23 women suffering of anterior knee pain (mean age: 29.7, SD 8.3 years; range: 16-45 years). MRI of 97 knees we...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/j.ejrad.2014.03.007

    authors: Ruiz Santiago F,Pozuelo Calvo R,Almansa López J,Guzmán Álvarez L,Castellano García MDM

    更新日期:2014-06-01 00:00:00

  • Correlation between high-resolution computed tomography and galactomannan antigenemia in adult hematologic patients at risk for invasive aspergillosis.

    abstract:OBJECTIVES:To analyse the predominant radiological pattern of pulmonary lesions in adult hematologic patients at risk for invasive aspergillosis (IA) together with the results of serial serum Aspergillus galactomannan antigen testing (GM). MATERIAL AND METHODS:In a prospective study for patients at high risk of asperg...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/j.ejrad.2008.03.026

    authors: Hidalgo A,Parody R,Martino R,Sánchez F,Franquet T,Giménez A,Blancas C

    更新日期:2009-07-01 00:00:00

  • Computational radiology in skeletal radiography.

    abstract::Recent years have brought rapid developments in computational image analysis in musculo-skeletal radiology. Meanwhile the algorithms have reached a maturity that makes initial clinical use feasible. Applications range from joint space measurement to erosion quantification, and from fracture detection to the assessment...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/j.ejrad.2009.05.053

    authors: Peloschek P,Nemec S,Widhalm P,Donner R,Birngruber E,Thodberg HH,Kainberger F,Langs G

    更新日期:2009-11-01 00:00:00

  • Can different regions of interest influence the diagnosis of benign and malignant breast lesions using quantitative parameters of contrast-enhanced sonography?

    abstract:OBJECTIVES:To evaluate the diagnostic utility of quantitative parameters which generated in different regions of interests (ROIs) of benign and malignant breast lesions using contrast-enhanced sonography(CEUS). MATERIALS AND METHODS:130 patients were evaluated with contrast harmonic imaging after the injection of a bo...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/j.ejrad.2018.09.005

    authors: Li J,Guo L,Yin L,Fang H,Ye W,Zhao B,Liu Y,Xu T

    更新日期:2018-11-01 00:00:00

  • Assessment of right ventricular dysfunction in end-stage renal disease patients on maintenance haemodialysis by cardiac magnetic resonance imaging.

    abstract:PURPOSE:To assess right ventricular (RV) dysfunction in end-stage renal disease (ESRD) patients on maintenance haemodialysis (HD) by cardiac magnetic resonance (CMR) imaging and determined the risk factors associated with RV dysfunction. MATERIALS AND METHODS:Fifty ESRD patients on maintenance HD and 16 age- and gende...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/j.ejrad.2018.02.036

    authors: Peng W,Li Z,Xu H,Xia C,Guo Y,Zhang J,Liu K,Li Y,Pu J,Zhang H,Cui T

    更新日期:2018-05-01 00:00:00

  • Image-guided tumor ablation for the treatment of recurrent non-small cell lung cancer within the radiation field.

    abstract:PURPOSE:The treatment options for non-small-cell lung cancer (NSCLC) that recurs after irradiation are limited. Image-guided percutaneous thermal ablation is an effective option in treating NSCLC that may provide an alternative to reirradiation. The purpose of this paper is to determine the survival and palliative bene...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/j.ejrad.2010.09.042

    authors: Leung VA,DiPetrillo TA,Dupuy DE

    更新日期:2011-12-01 00:00:00

  • Iodine contrast-to-noise ratio improvement at unit dose and contrast media volume reduction in whole-body photon-counting CT.

    abstract:PURPOSE:To assess the dose-normalized iodine contrast-to-noise-ratio (CNRD) improvement and contrast media reduction potential obtained with photon-counting (PC) CT compared to conventional energy-integrating (EI) CT as a function of patient size and tube voltage. METHOD:Images of a semi-anthropomorphic phantom of dif...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/j.ejrad.2020.108909

    authors: Sawall S,Klein L,Amato C,Wehrse E,Dorn S,Maier J,Heinze S,Schlemmer HP,Ziener CH,Uhrig M,Kachelrieß M

    更新日期:2020-05-01 00:00:00

  • CT and MRI findings after stereotactic resection of brain lesions.

    abstract:OBJECTIVE:To describe postoperative CT and MRI findings and their time course in uncomplicated cases after stereotactic volumetric resections of brain lesions. MATERIALS AND METHODS:One-hundred twenty-eight imaging studies (CT, 86; MRI, 42), performed 6 h to 2 years after 52 stereotactic operations, were retrospective...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/s0720-048x(96)00774-7

    authors: Herman M,Pozzi-Mucelli RS,Skrap M

    更新日期:1996-11-01 00:00:00

  • Nephrogenic systemic fibrosis--implications for nephrologists.

    abstract::Nephrogenic systemic fibrosis (NSF) is a debilitating disorder seen in-patient with advanced chronic kidney disease (CKD). Recent evidence suggests a link between NSF and the administration of gadolinium-based contrast agents (Gd-CA). In addition, other risk factors have also been suggested to facilitate the developme...

    journal_title:European journal of radiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.ejrad.2008.01.028

    authors: Saab G,Abu-Alfa A

    更新日期:2008-05-01 00:00:00

  • Synthesized image processing in clinical neurosurgery.

    abstract::In an effort to achieve efficient image management in clinical neurosurgery utilizing a local image filing system (EFPACS, Fuji Electric Co., Ltd), adequate image-processing and display techniques were developed. One is a method whereby the anatomical location of the thalamic and basal ganglion lesions is determined b...

    journal_title:European journal of radiology

    pub_type: 杂志文章

    doi:10.1016/0720-048x(90)90092-p

    authors: Kikuchi K,Kowada M,Ogayama H,Sasanuma J,Watanabe K

    更新日期:1990-01-01 00:00:00