Abstract:
OBJECTIVE:We investigated whether the prerequisite of the maximum slope and deconvolution methods are satisfied in pancreatic perfusion CT and whether the measured parameters between these algorithms are correlated. METHODS:We examined nine beagles injected with iohexol (200 mgI kg(-1)) at 5.0 ml s(-1). The abdominal aorta and splenic and celiac arteries were selected as the input arteries and the splenic vein, the output veins. For the maximum slope method, we determined the arterial contrast volume of each artery by measuring the area under the curve (AUC) and compared the peak enhancement time in the pancreas with the contrast appearance time in the splenic vein. For the deconvolution method, the artery-to-vein collection rate of contrast medium was calculated. We calculated the pancreatic tissue blood flow (TBF), tissue blood volume (TBV), and mean transit time (MTT) using both algorithms and investigated their correlation based on vessel selection. RESULTS:The artery AUC significantly decreased as it neared the pancreas (P<0.01). In all cases, the peak time of the pancreas (11.5±1.6) was shorter than the appearance time (14.1±1.6) in the splenic vein. The splenic artery-vein combination exhibited the highest collection rate (91.1%) and was the only combination that was significantly correlated between TBF, TBV, and MTT in both algorithms. CONCLUSION:Selection of a vessel nearest to the pancreas is considered as a more appropriate prerequisite. Therefore, vessel selection is important in comparison of the semi-quantitative parameters obtained by different algorithms.
journal_name
Eur J Radioljournal_title
European journal of radiologyauthors
Kishimoto M,Tsuji Y,Katabami N,Shimizu J,Lee KJ,Iwasaki T,Miyake Y,Yazumi S,Chiba T,Yamada Kdoi
10.1016/j.ejrad.2009.06.016subject
Has Abstractpub_date
2011-01-01 00:00:00pages
175-81issue
1eissn
0720-048Xissn
1872-7727pii
S0720-048X(09)00374-Xjournal_volume
77pub_type
杂志文章abstract::While urothelial carcinoma is a very common tumor, involvement of the upper tract is relatively uncommon. Consequently, there are no consensus imaging recommendations for upper tract disease. CT urography is the dominant imaging modality for the upper tract, but despite its excellent performance characteristics and be...
journal_title:European journal of radiology
pub_type: 杂志文章,评审
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journal_title:European journal of radiology
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pub_type: 杂志文章,评审
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pub_type: 临床试验,杂志文章
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journal_title:European journal of radiology
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