Abstract：
OBJECTIVE:To assess the usefulness of the spectral curve slope of dual-energy CT (DECT) for differentiating between hepatocellular carcinoma (HCC), hepatic metastasis, hemangioma (HH) and cysts. METHODS:In total, 121 patients were imaged in the portal venous phase using dual-energy mode. Of these patients, 23 patients had HH, 28 patients had HCC, 40 patients had metastases and 30 patients had simple cysts. The spectral curves of the hepatic lesions were derived from the 40-190 keV levels of virtual monochromatic spectral imaging. The spectral curve slopes were calculated from 40 to 110 keV. The slopes were compared using the Kruskal-Wallis test. Receiver operating characteristic curves (ROC) were used to determine the optimal cut-off value of the slope of the spectral curve to differentiate between the lesions. RESULTS:The spectral curves of the four lesion types had different baseline levels. The HH baseline level was the highest followed by HCC, metastases and cysts. The slopes of the spectral curves of HH, HCC, metastases and cysts were 3.81 ± 1.19, 1.49 ± 0.57, 1.06 ± 0.76 and 0.13 ± 0.17, respectively. These values were significantly different (P<0.008). Based on ROC analysis, the respective diagnostic sensitivity and specificity were 87% and 100% for hemangioma (cut-off value ≥ 2.988), 82.1% and 65.9% for HCC (cut-off value 1.167-2.998), 65.9% and 59% for metastasis (cut-off value 0.133-1.167) and 44.4% and 100% for cysts (cut-off value ≤ 0.133). CONCLUSION:Quantitative analysis of the DECT spectral curve in the portal venous phase can be used to determine whether tumors are benign or malignant.
journal_name
Eur J Radioljournal_title
European journal of radiologyauthors
Wang Q,Shi G,Qi X,Fan X,Wang Ldoi
10.1016/j.ejrad.2014.07.009subject
Has Abstractpub_date
2014-10-01 00:00:00pages
1759-64issue
10eissn
0720-048Xissn
1872-7727pii
S0720-048X(14)00361-1journal_volume
83pub_type
杂志文章abstract：:Hypogonadism, resulting from iron-induced pituitary dysfunction, is the most frequently reported complication in patients with beta-thalassaemia major. The aim of this study was to evaluate pituitary Magnetic Resonance Imaging (MRI) signal intensity reduction, on T2*-weighted images, as a marker of pituitary iron over...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2006.11.016
更新日期：2007-04-01 00:00:00
abstract：OBJECTIVE:A software program was developed simulating a compartmental model of blood circulation based on differential equations. The aim of this study was to compare software-simulated levels of hepatic enhancement with the true values in patients and to test how many patients reach the simulated hepatic enhancement l...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/S0720-048X(03)00217-1
更新日期：2004-07-01 00:00:00
abstract：:Ultrasound contrast agents were originally introduced to enhance the Doppler signals when detecting vessels with low velocity flow or when imaging conditions were sub-optimal. Contrast agents showed additional properties, it was discovered that a parenchymal enhancement phase in the liver followed the enhancement of t...
journal_title：European journal of radiology
pub_type： 杂志文章,评审
doi：10.1016/j.ejrad.2004.03.022
更新日期：2004-06-01 00:00:00
abstract：PURPOSE:To develop and evaluate the performance of a fully-automated convolutional neural network (CNN)-based algorithm to evaluate hepatobiliary phase (HBP) adequacy of gadoxetate disodium (EOB)-enhanced MRI. Secondarily, we explored the potential of the proposed CNN algorithm to reduce examination length by applying ...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2020.108837
更新日期：2020-03-01 00:00:00
abstract：:Positron emission tomography (PET) has proven to be a clinically valuable imaging modality, particularly for oncology staging and therapy follow-up. The introduction of combined PET/CT imaging has helped address challenging imaging situations when anatomical information on PET-only was inadequate for accurate lesion l...
journal_title：European journal of radiology
pub_type： 杂志文章,评审
doi：10.1016/j.ejrad.2009.12.021
更新日期：2010-03-01 00:00:00
abstract：:To investigate the relationship between liver glucose, glycogen, and plasma glucose in diabetic patients, in vivo liver carbon-13 magnetic resonance spectroscopy ((13)C MRS) with a clinical 3.0T MR system was performed. Subjects were healthy male volunteers (n=5) and male type-2 diabetic patients (n=5). Pre- and durin...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2008.10.019
更新日期：2010-02-01 00:00:00
abstract：OBJECTIVES:The purpose of this study is to validate the usefulness of shear wave elastography (SWE) in predicting thyroid malignancy with a large-scale quantitative SWE data. METHODS:This restrospective study included 476 thyroid nodules in 453 patients who underwent gray-scale US and SWE before US-guided fine-needle ...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2014.11.019
更新日期：2015-03-01 00:00:00
abstract：OBJECTIVE:To determine whether there is an association between abnormal primary peristalsis in the esophagus and gastroesophageal reflux (GER) on barium studies. METHODS:A computerized search of radiologic reports revealed 151 patients with esophageal dysmotility (characterized by intermittently decreased or absent pe...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2006.02.002
更新日期：2006-07-01 00:00:00
abstract：OBJECTIVE:To investigate the distribution of an ultrasound-guided intra-articular (IA) injection in the wrist joint of patients with rheumatoid arthritis (RA). METHODS:An ultrasound-guided IA drug injection into the wrist joint was performed in 17 patients with 1 ml methylprednisolone (40 mg/ml), 0.5 ml Lidocaine (5mg...
journal_title：European journal of radiology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ejrad.2007.08.037
更新日期：2009-02-01 00:00:00
abstract：:Only few publication have so far been known on case histories in the context of CT-findings of hepatic adenoma (HA). An analysis was, therefore, made of the findings of ten patients with HA. Precontrast and postcontrast scans (dynamic CT), densitometric evaluations (gamma-fit) and "profile" determination were taken in...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：
更新日期：1987-02-01 00:00:00
abstract：:A simple generalization of the diffraction enhanced imaging (DEI) technique, called generalized DEI (GDEI), and its application to tomographic imaging are herein presented. In planar imaging, the GDEI algorithm combines three input images (acquired at different analyzer positions) to deliver three parametric images, p...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2008.04.026
更新日期：2008-12-01 00:00:00
abstract：PURPOSE:This study aims to explore wall enhancement characteristics of vertebrobasilar nonsaccular aneurysms (VBNAs) and their relationship to clinical symptoms. METHODS:We retrospectively analyzed VBNAs in the high resolution MR vessel wall imaging (HR-VWI) databases at two institutions. The aneurysmal basic characte...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2020.109064
更新日期：2020-08-01 00:00:00
abstract：:Rapid advancements in multidetector row computed tomography (MDCT) are beginning to revolutionise cardiac imaging applications. As a consequence, coronary CT angiography (CTA) is fast emerging as a highly effective, noninvasive imaging technique for the assessment of coronary artery disease (CAD). Technology is improv...
journal_title：European journal of radiology
pub_type： 杂志文章,评审
doi：10.1016/j.ejrad.2010.02.011
更新日期：2011-08-01 00:00:00
abstract：PURPOSE:To assess the effect of parenteral butylscopolamine on magnetic resonance cholangiopancreatography (MRCP) image quality. MATERIALS AND METHODS:The 3D free-breathing respiratory-compensated MRCP images (mean acquisition time 7min) of 94 consecutive non-paired patients (47 with and 47 without 20mg intramuscular ...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2012.11.023
更新日期：2013-04-01 00:00:00
abstract：:Physical exercise and sports increase muscular mass and the remodelling process of bones. The increment of bone depends on the type and the quality of sport. Short-term high-performance activities such as sprint, tennis, fencing lead to increased bone mineral density as well as weight lifting or heavy athletics. Swimm...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/s0720-048x(97)00113-7
更新日期：1998-09-01 00:00:00
abstract：:Aspiration of the hip joint in the setting of a potentially infected total hip replacement is occasionally unsuccessful under fluoroscopic guidance because of periarticular heterotopic bone. Of 136 consecutive patients with total hip replacements who were referred to the radiology department for hip aspiration because...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/0720-048x(95)00606-q
更新日期：1995-05-01 00:00:00
abstract：PURPOSE:To determine whether imaging parameters derived from intravoxel incoherent motion (IVIM) diffusion weighted imaging (DWI) vary according to tumor-stroma ratio(TSR) or dominant stroma type of breast cancer. METHODS:We prospectively enrolled 77 patients with breast cancer who underwent IVIM DWI on a 3.0 T MR sca...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2019.108686
更新日期：2019-11-01 00:00:00
abstract：BACKGROUND:Biopsy with demonstration of the infectious organism is the gold standard for diagnosing spondylodiscitis. The purpose of this study is to evaluate the positive culture rate of image-guided percutaneous biopsy in cases of radiologically suspected and unsuspected spinal osteomyelitis and to assess the role of...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2011.01.125
更新日期：2012-05-01 00:00:00
abstract：PURPOSE:The purpose of this study was to characterize gliomatosis cerebri on magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS), and to analyze the value of these two techniques in diagnosis and differential diagnosis of gliomatosis cerebri. MATERIALS AND METHODS:MR images of 14 patients with g...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2006.03.001
更新日期：2006-08-01 00:00:00
abstract：PURPOSE:To evaluate the diagnostic performance of susceptibility-weighted magnetic resonance imaging (SWMR) for the differentiation of sclerotic and non-sclerotic Modic changes (MC) of the spine compared to computed tomography (CT) and radiographs. MATERIALS AND METHODS:The Institutional Ethics-Review-Board approved t...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2016.12.024
更新日期：2017-03-01 00:00:00
abstract：PURPOSE:Although delayed enhanced CMR has become a reference method for infarct size quantification, there is no ideal method to quantify total infarct size in a routine clinical practice. In a prospective study we compared the performance and post-processing time of a global visual scoring method to standard quantitat...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2009.09.027
更新日期：2011-04-01 00:00:00
abstract：:A case of mesenchymal hamartoma of the liver in an 18-month-old boy is reported. CT and US revealed a large, cystic tumour surrounded by a thick wall. In the lower portion of the tumour, a small solid component was recognized on CT. Angiography revealed marked arterial displacement, fine tumour vessels and a large rad...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：
更新日期：1983-11-01 00:00:00
abstract：:The purpose of this review is to outline recent trends in contrast agent development for magnetic resonance imaging. Up to now, small molecular weight gadolinium chelates are the workhorse in contrast enhanced MRI. These first generation MR contrast agents distribute into the intravascular and interstitial space, thus...
journal_title：European journal of radiology
pub_type： 杂志文章,评审
doi：10.1016/s0720-048x(02)00332-7
更新日期：2003-04-01 00:00:00
abstract：:The purpose of this article is to provide an up-to-date view on the spectrum of applications of volume perfusion-CT in the liver. Volume perfusion-CT yields important information on liver architecture and function by enabling quantification of dual liver parenchymal blood supply. Additional characterization of diffuse...
journal_title：European journal of radiology
pub_type： 杂志文章,评审
doi：10.1016/j.ejrad.2011.04.010
更新日期：2012-07-01 00:00:00
abstract：OBJECTIVE:To assess virtual non-enhanced dual energy computed tomography (DECT) reconstruction as a potential alternative to true non-enhanced thoracic and abdominal CT scans in patients with suspected active hemorrhage. METHODS AND MATERIALS:Ninety-seven consecutive patients with suspected active bleeding, who underw...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2018.10.026
更新日期：2018-12-01 00:00:00
abstract：OBJECTIVE:Various degrees of aortic valve rotation may be seen in individuals with no history of congenital cardiovascular malformations, but its association with aortic sizes has not been studied. METHODS:Gated computed tomographic (CT angiograms in 217 patients were studied (66.7±15; 22-97 years old)). Aortic diamet...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2017.01.009
更新日期：2017-04-01 00:00:00
abstract：PURPOSE:To determine the prevalence and characterise the significance of incidental findings on whole-body MRI in paediatric and adult populations. METHODS:A retrospective, single-institution study over a period of 8 years. The study population comprised 325 paediatric (0-18 yrs) patients and 148 adults (19-40 yrs) re...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2020.109156
更新日期：2020-09-01 00:00:00
abstract：PURPOSE:To validate the diagnostic performance of quadruple phase low tube voltage liver CT through the comparison with Gd-EOB-DTPA enhanced liver MRI for the detection of HCC. MATERIALS AND METHODS:Non-obese patients (38 men, eight women) with 68 HCCs underwent quadruple-phase CT at 16 MDCT (using low tube voltage, 8...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2011.12.033
更新日期：2012-04-01 00:00:00
abstract：:Several diffusion tensor imaging tractography (DTT) have been adopted to construct the living human brain corticospinal tract. In this Note, we applied method "A" as recently described and used by "Lin CC, Tsai MY, Lo YC, et al. Reproducibility of corticospinal diffusion tensor tractography innormal subjects and hemip...
journal_title：European journal of radiology
pub_type： 评论,信件
doi：10.1016/j.ejrad.2014.05.022
更新日期：2014-09-01 00:00:00
abstract：PURPOSE:To evaluate the pattern and risks for intrahepatic recurrence after percutaneous radiofrequency (RF) ablation for hepatocellular carcinoma (HCC). MATERIALS AND METHODS:We studied 62 patients with 72 HCCs (< or =4 cm) who were treated with percutaneous RF ablation. The mean follow-up period was 19.1 months (6.0...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2006.03.007
更新日期：2006-09-01 00:00:00
