Abstract：
:The purpose of this review is to outline recent trends in contrast agent development for magnetic resonance imaging. Up to now, small molecular weight gadolinium chelates are the workhorse in contrast enhanced MRI. These first generation MR contrast agents distribute into the intravascular and interstitial space, thus allowing the evaluation of physiological parameters, such as the status or existence of the blood-brain-barrier or the renal function. Shortly after the first clinical use of paramagnetic metallochelates in 1983, compounds were suggested for liver imaging and enhancing a cardiac infarct. Meanwhile, liver specific contrast agents based on gadolinium, manganese or iron become reality. Dedicated blood pool agents will be available within the next years. These gadolinium or iron agents will be beneficial for longer lasting MRA procedures, such as cardiac imaging. Contrast enhanced lymphography after interstitial or intravenous injection will be another major step forward in diagnostic imaging. Metastatic involvement will be seen either after the injection of ultrasmall superparamagnetic iron oxides or dedicated gadolinium chelates. The accumulation of both compound classes is triggered by an uptake into macrophages. It is likely that similar agents will augment MRI of atheriosclerotic plaques, a systemic inflammatory disease of the arterial wall. Thrombus-specific agents based on small gadolinium labeled peptides are on the horizon. It is very obvious that the future of cardiovascular MRI will benefit from the development of new paramagnetic and superparamagnetic substances. The expectations for new tumor-, pathology- or receptor-specific agents are high. However, is not likely that such a compound will be available for daily routine MRI within the next decade.
journal_name
Eur J Radioljournal_title
European journal of radiologyauthors
Weinmann HJ,Ebert W,Misselwitz B,Schmitt-Willich Hdoi
10.1016/s0720-048x(02)00332-7keywords:
subject
Has Abstractpub_date
2003-04-01 00:00:00pages
33-44issue
1eissn
0720-048Xissn
1872-7727pii
S0720048X02003327journal_volume
46pub_type
杂志文章,评审abstract：:Nosocomial pneumonia is the most frequent hospital-acquired infection. In mechanically ventilated patients admitted to an intensive-care unit as many as 7-41% may develop pneumonia. The role of imaging is to identify the presence, location and extent of pulmonary infection and the presence of complications. However, t...
journal_title：European journal of radiology
pub_type： 杂志文章,评审
doi：10.1016/j.ejrad.2007.09.018
更新日期：2008-03-01 00:00:00
abstract：PURPOSE:To determine whether ultrasound is of any value in male patients presenting with focal symptoms who have classic features of gynecomastia but no concerning findings on mammography. MATERIALS AND METHODS:Over a 3-year period, all male patients who underwent mammographic evaluation were identified in this retros...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2013.09.021
更新日期：2014-01-01 00:00:00
abstract：:Constantly increasing number of surgical procedures on the soft tissues of and around the knee generates the need for postoperative soft tissue assessment. Sports medicine is constantly seeking new--faster, better, more efficient--ways to help patients, especially competitive athletes to come back to their full activi...
journal_title：European journal of radiology
pub_type： 杂志文章,评审
doi：10.1016/j.ejrad.2007.01.018
更新日期：2007-04-01 00:00:00
abstract：:The different features of 821 acoustic shadows recorded during abdominal US examinations were analysed to find out whether any of the features may be used in routine work to help to identify the often invisible structure casting the shadow. A constant shadow with closely spaced high level reverberation echoes is stron...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：
更新日期：1985-05-01 00:00:00
abstract：:Functional magnetic resonance imaging (fMRI) has become the primary non-invasive method for investigating the human brain function. With an increasing number of ultra-high field MR systems worldwide possibilities of higher spatial and temporal resolution in combination with increased sensitivity and specificity are ex...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2011.09.025
更新日期：2013-05-01 00:00:00
abstract：:In this study, we investigated whether assessment of the tumor perfusion by dynamic contrast-enhanced magnetic resonance imaging (DCE MRI) enables to estimate the morphologic grading of renal cell carcinomas. A total of 21 patients with suspected renal cell cancer were examined using a Gadobutrol-enhanced, dynamic sat...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2009.05.042
更新日期：2010-06-01 00:00:00
abstract：PURPOSE:To evaluate the diagnostic efficacy of curved planar reformations along the duct (long-axis CPR) and series of reformations perpendicular to the duct (short-axis MPR) in evaluating T-factors of pancreaticobiliary malignancy. MATERIALS AND METHODS:Twenty-five patients with surgically proven pancreaticobiliary m...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2007.01.022
更新日期：2007-07-01 00:00:00
abstract：PURPOSE:Evaluation of percutaneous recanalization of obstructed iliac as well as superficial femoral arteries (SFAs) in patients with peripheral arterial obstructive disease (PAOD). MATERIAL AND METHODS:The data of 195 consecutive patients with 285 obstructions of the common and or external iliac artery as well as the...
journal_title：European journal of radiology
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.ejrad.2010.04.016
更新日期：2010-07-01 00:00:00
abstract：:Imaging plays an important role in the staging of nasopharyngeal carcinoma. Accurate staging is necessary, as the treatment is directly dependent on stage. Clinical examination provides information on mucosal involvement but is unable to determine the deep extension or the presence of skull base invasion or intracrani...
journal_title：European journal of radiology
pub_type： 杂志文章,评审
doi：10.1016/j.ejrad.2008.03.029
更新日期：2008-06-01 00:00:00
abstract：OBJECTIVE:The aim of our study was to determine the impact of treatment with exogenous surfactant (ES) and high frequency oscillatory ventilation (HFOV) on the radiological appearance and clinical course of hyaline membrane disease (HMD) in new-born infants. MATERIALS AND METHODS:New-born infants (18) (median weight, ...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/s0720-048x(97)00153-8
更新日期：1998-10-01 00:00:00
abstract：OBJECTIVE:To compare the quality of contrast enhancement and hepatic CT images acquired using bolus tracking technique at two different time points and those acquired with fixed scan delay technique using a previous bolus tracking data. MATERIALS AND METHODS:Fifty patients who underwent 3 different hepatic CT exams (2...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2012.02.022
更新日期：2012-11-01 00:00:00
abstract：:Phlebography has proved to be the most reliable method to diagnose a deep venous thrombosis of a lower leg. In this study it is attempted to evaluate the accuracy of thermography in diagnosing a deep venous thrombosis. The series comprises 125 patients which were investigated with thermography and phlebography. A diag...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：
更新日期：1985-11-01 00:00:00
abstract：OBJECTIVE:In this study the hypothesis that the thickness of the thinnest part of the thrombus, combined with bleeding into the intraluminal thrombus (ILT), is associated with a possible higher risk of abdominal aortic aneurysm (AAA) rupture was investigated, independently of aneurysm diameter, by using angio-CT. This ...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2014.12.022
更新日期：2015-04-01 00:00:00
abstract：OBJECTIVE:The aim of our study was to systematically compare different methodologies to establish an evidence-based approach based on tendon thickness and structure for sonographic diagnosis of supraspinatus tendinopathy when compared to MRI. METHODS:US was obtained from 164 symptomatic patients with supraspinatus ten...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2014.02.021
更新日期：2014-06-01 00:00:00
abstract：PURPOSE:To evaluate the effects of aging on skeletal muscle stiffness in relaxed and contracted status using shear wave elastography (SWE). MATERIALS AND METHODS:A total of 57 participants were enrolled to this institutional review board approved prospective study. Medial head of the gastrocnemius muscle (GM) of all p...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2020.109038
更新日期：2020-07-01 00:00:00
abstract：PURPOSE:To assess the value of CT-perfusion in determining the quantitative vascularization features of early hepatocellular carcinoma (HCC) in cirrhotic patients. MATERIALS AND METHODS:A total of 35 cirrhotic patients with single histologically proven HCC not exceeding 3cm in diameter underwent conventional triple-ph...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2008.10.014
更新日期：2010-01-01 00:00:00
abstract：:The ability of PI measurements to differentiate between acute rejection and ATN was investigated in 37 patients, who were frequently examined by duplex Doppler after kidney transplant. Absolute PI values as well as increase in PI were recorded and the clinical course was correlated with these pulsatility measurements....
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/0720-048x(92)90057-g
更新日期：1992-01-01 00:00:00
abstract：:The aim of this prospective study was to assess the accuracy of modern ultrasonography in diagnostic imaging of meniscal tears. One hundred and sixty menisci were evaluated in 80 patients (42 females, 38 males, mean age=36.2 years, range=16-70 years). Inclusion criteria for the study were twofold: clinical suspicion o...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2011.09.013
更新日期：2012-09-01 00:00:00
abstract：PURPOSE:To evaluate the value of intravoxel incoherent motion (IVIM) histogram analysis based on whole tumor volume in predicting microvascular invasion (MVI) of single hepatocellular carcinoma (HCC). MATERIALS AND METHODS:The study enrolled 41 patients with pathologically proven HCCs who underwent IVIM diffusion-weig...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2018.05.032
更新日期：2018-08-01 00:00:00
abstract：AIM:Comparison of the diagnostic value of cinefluoroscopy and simple fluoroscopy in the detection of calcification in coronary arteries. PATIENTS AND METHODS:Data were prospectively obtained from 143 patients in whom simple fluoroscopy as well as cinecoronary arteriography were performed. Excluded were patients with a...
journal_title：European journal of radiology
pub_type： 临床试验,杂志文章
doi：10.1016/0720-048x(94)00597-6
更新日期：1995-03-01 00:00:00
abstract：:Computed tomography (CT) and magnetic resonance imaging (MRI) are well established imaging modalities to examine the facial nerve as well as the course of the facial nerve itself. High spatial resolution is guaranteed not only in the x- and y-axis, but also in the z-axis using multislice spiral CT. With this technique...
journal_title：European journal of radiology
pub_type： 杂志文章,评审
doi：10.1016/s0720-048x(01)00381-3
更新日期：2001-11-01 00:00:00
abstract：OBJECTIVE:To estimate a frequency of obstetric anal sphincters defects in women after vaginal delivery. METHODS:The study included 102 women, aged from 16 to 40 years (mean age 28.6 years). 28 women had perineal lacerations of 3rd and 4th degree. 22 women had instrumental delivery. Anal endosonography was performed on...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2009.10.008
更新日期：2011-04-01 00:00:00
abstract：PURPOSE:To compare radiation dose, image quality and diagnostic performance of low dose CT enterography (CTE) protocol combined with iterative reconstruction algorithm (iDose(4)) with standard dose CTE in follow-up of patients with known Crohn's disease (CD). MATERIALS AND METHOD:Thirty-six patients (12 females), with...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2015.10.011
更新日期：2016-01-01 00:00:00
abstract：PURPOSE:To examine the clinical significance of persistent renal enhancement after iodixanol administration. METHODS:We retrospectively studied 166 consecutive patients who underwent non-enhanced abdominopelvic CT within 7 days after receiving intra-arterial (n=99) or intravenous (n=67) iodixanol. Renal attenuation wa...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2011.02.044
更新日期：2011-11-01 00:00:00
abstract：:In the present study ultrasonography observed the tail of the pancreas more frequently through the spleen than by any other approach. If the splenic approach fails, examination through the fluid-filled stomach may be tried. ...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：
更新日期：1986-05-01 00:00:00
abstract：PURPOSE:Apparent Diffusion Coefficient (ADC) measurements are increasingly used for assessing breast cancer response to neoadjuvant chemotherapy although little data exists on ADC measurement reproducibility. The purpose of this work was to investigate and characterise the magnitude of errors in ADC measures that may b...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2015.05.032
更新日期：2015-09-01 00:00:00
abstract：:Fluid-attenuated inversion recovery imaging (=flair imaging) is widely used as primary screening sequence in various investigation protocols, due to its high lesion contrast and sensitivity in detection of parenchymatous and leptomeningeal disease. An additional increase of sensitivity for detection of lesions may be ...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2004.11.008
更新日期：2005-08-01 00:00:00
abstract：INTRODUCTION:Concerning the preoperative clinical diagnostic work-up of glioma patients, tumor heterogeneity challenges the oncological therapy. The current study assesses the performance of a multimodal imaging approach to differentiate between areas in malignant gliomas and to investigate the extent to which such a c...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2014.02.006
更新日期：2014-05-01 00:00:00
abstract：PURPOSE:This study aimed to evaluate the usefulness of four-dimensional CTA before and after embolization treatment with ONYX-18 in eleven patients with cranial dural arteriovenous fistulas, and to compare the results with those of the reference standard DSA. PATIENTS AND METHODS:Eleven patients with cranial dural art...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：10.1016/j.ejrad.2015.03.009
更新日期：2015-06-01 00:00:00
abstract：:The diagnosis of aortic dissection can be made with certainty when computed tomography or aortography reveals two lumina and a intimal flap between them. If the false lumen is thrombosed, the differential diagnosis between dissection and aneurysm with intraluminal thrombus is difficult. High resolution computed tomogr...
journal_title：European journal of radiology
pub_type： 杂志文章
doi：
更新日期：1986-11-01 00:00:00
