Clinical utility of real-time ultrasound-multimodality fusion guidance for percutaneous biopsy of focal liver lesions.

Abstract:

OBJECTIVES:To prospectively evaluate the clinical value of real-time ultrasonography (US)-computed tomography (CT)/magnetic resonance imaging (MRI) fusion imaging for percutaneous needle biopsy of focal liver lesions (FLLs), and to compare its biopsy success rate with that of conventional US-guided biopsy in a propensity-score matched group. METHODS:This study was approved by our Institutional Review Board and informed consent was obtained from all patients enrolled in the prospective study group. Ninety patients referred to the Department of Radiology for percutaneous biopsy of FLLs were enrolled in this study. Tumor visibility, attainment of a safe access route, and technical feasibility were assessed on conventional US first and later on real-time fusion imaging by one of four abdominal radiologists. Thereafter, differences in scores between real-time fusion imaging and conventional US were determined. In addition, overall diagnostic success rates of a real-time fusion imaging-guided biopsy group and a propensity-score matched, conventional US-guided biopsy group, consisting of 100 patients used as historical control, were compared. RESULTS:With real-time fusion imaging, tumor visibility, attainment of a safe access route, and operator's technical feasibility were significantly improved compared with conventional US (P < .001). In addition, all invisible (n = 13) and not feasible (n = 10) FLLs on conventional US became visible and feasible for percutaneous US-guided biopsy after applying the fusion system. The diagnostic success rate of real-time fusion-guided biopsy was 94.4% (85/90), which was significantly better than that obtained with the conventional US-guided biopsy (94.4% vs. 83%, P < .03), with reduced biopsy procedure times (7.1 ± 3.5 vs. 9.7 ± 2.8, P < .02). CONCLUSIONS:Real-time US-CT/MR fusion imaging guidance was able to provide clinical value for percutaneous needle biopsy of FLLs by improving the diagnostic success rate of biopsy and by reducing procedure time.

journal_name

Eur J Radiol

authors

Ahn SJ,Lee JM,Chang W,Lee SM,Kang HJ,Yang HK,Han JK

doi

10.1016/j.ejrad.2018.04.002

subject

Has Abstract

pub_date

2018-06-01 00:00:00

pages

76-83

eissn

0720-048X

issn

1872-7727

pii

S0720-048X(18)30121-9

journal_volume

103

pub_type

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