Abstract:
OBJECTIVE:The purpose of this study was to evaluate the enhancement pattern and the diagnostic accuracy of gadofluorine M in comparison with gadopentetate dimeglumine in a rabbit VX2 tumor model. MATERIALS AND METHODS:Thirteen rabbits with experimentally induced VX2 carcinomas in the thighs underwent sequential T1-weighted enhancement MR imaging using a 3.0T MR imager, first with gadopentetate dimeglumine, and then 24 (n=4) or 4h (n=9) later with gadofluorine M. In 4 rabbits with 13 tumors, the time-percentage enhancement (PE; i.e., percentage of signal intensity increase) curve was obtained for up to 24h for each contrast agent. In 9 rabbits with 49 tumors (random numbers of VX2 tumors were inoculated at random sites in the thigh), 3 readers unaware of the histopathologic results interpreted the MR images and determined the number and conspicuity level of the detected tumors. The reference standard was the histopathology of the specimen. RESULTS:The time-to-peak PE for gadopentetate dimeglumine was 1min and gadopentetate dimeglumine showed a rapid washout pattern. The time-to-peak PE for gadofluorine M was 30min and gadofluorine M showed a plateau enhancement pattern for up to 24h. The peak PE of gadofluorine M was approximately twice that of the same dose of gadopentetate dimeglumine (108.2±14.8 vs. 51.5±24.0). The sensitivities for detecting VX2 tumors by 3 readers were 89.8% (44/49), 85.7% (42/49), and 95.9% (47/49) for gadopentetate dimeglumine-enhanced MR imaging, and 87.8% (43/49), 89.8% (44/49), and 89.8% (44/49) for gadofluorine M-enhanced MR imaging. No significant differences in the sensitivities existed between the two contrast agents for any reader. However, the conspicuity level of tumors was superior with gadofluorine M-enhanced MR imaging for two readers and similar for the other reader. CONCLUSION:Gadofluorine M showed strong and plateau enhancement of tumors for up to 24h. In the reader study, gadofluorine M showed better conspicuity for VX2 tumors than gadopentetate dimeglumine, but had a similar sensitivity.
journal_name
Eur J Radioljournal_title
European journal of radiologyauthors
Kim SJ,Moon WK,Choi SH,Chang JM,Cho Ndoi
10.1016/j.ejrad.2011.03.044subject
Has Abstractpub_date
2012-08-01 00:00:00pages
1751-7issue
8eissn
0720-048Xissn
1872-7727pii
S0720-048X(11)00314-7journal_volume
81pub_type
杂志文章abstract:OBJECTIVES:Bronchial thermoplasty (BT) can be considered in the treatment of severe asthma to reduce airway smooth muscle mass and bronchoconstriction. We hypothesized that BT may thus have long-term effects on airway dimensions and air-trapping detectable by quantitative computed tomography (QCT). METHODS:Paired in- ...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2018.08.007
更新日期:2018-10-01 00:00:00
abstract:OBJECTIVE:Our purpose was, through the comparison of the characteristics of time-intensity curve on triple-phase dynamic contrast-enhanced MRI among groups of giant cell tumor of bone (GCTB), recurrent benign giant cell tumor of bone (RBGCTB), and secondary malignant giant cell tumor of bone (SMGCTB), to find clues to ...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2013.10.013
更新日期:2014-02-01 00:00:00
abstract::The management of trauma patients has become a very relevant issue and one of the major challenges in the western countries. In the assessment of politrauma patients, since the last 2 decades, radiological imaging methods have been increasingly used in order to provide a quick and thorough survey of craniocerebral, ce...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2006.04.021
更新日期:2006-09-01 00:00:00
abstract::Patients with extended vascular anomalies may suffer from significant aesthetic and functional impairment and represent a challenge to therapeutic planning, which is best met by an interdisciplinary concept. In agreement with the International Society for the Study of Vascular Anomalies (ISSVA), vascular lesions are c...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2010.04.009
更新日期:2010-07-01 00:00:00
abstract:PURPOSE:Thin-section CT is the modality of choice for morphological imaging the lung parenchyma, while proton-MRI might be used for functional assessment. However, the capability of MRI to visualize morphological parenchymal alterations in emphysema is undetermined. Thus, the aim of the study was to compare different M...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2008.09.029
更新日期:2010-01-01 00:00:00
abstract:PURPOSE:To assess and quantify the prevalence and co-occurence of a sellar floor lowering and empty sella phenomenon in patients with GH (growth hormone)-secreting pituitary adenoma. METHODS:A total number of 159 acromegalic patients were included in this study, as well as two control groups (150 patients with non-GH-...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2018.05.009
更新日期:2018-07-01 00:00:00
abstract::Large randomized trials have demonstrated the value of surgical intervention for symptomatic carotid artery disease in stroke prevention. More recently trials have also demonstrated benefit in asymptomatic patients. However, the benefit of surgery comes with significant burden in terms of a risk of both stroke at the ...
journal_title:European journal of radiology
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.ejrad.2006.05.022
更新日期:2006-10-01 00:00:00
abstract:PURPOSE:Airspace enlargement with fibrosis (AEF) has been identified pathologically as a smoking related change. We sought to identify the HRCT findings of AEF and search for distinguishing features from honeycombing. MATERIALS AND METHODS:50 patients (47 males; mean age 69) were evaluated. All had undergone lobectomy...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2015.01.015
更新日期:2015-05-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Grading of cerebral gliomas is important both in treatment decision and assessment of prognosis. The purpose of this study was to determine the diagnostic accuracy of grading cerebral gliomas by assessing the tumor heterogeneity using MRI texture analysis (MRTA). MATERIAL AND METHODS:95 patients...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2016.01.013
更新日期:2016-04-01 00:00:00
abstract:OBJECTIVES:The purpose was to evaluate whether BI-RADS (the Breast Imaging Recording and Data System) combined with UE (ultrasound elastography) could improve the differentiation and characterization of benign and malignant breast lesions by comparing with BI-RADS. METHODS:A total of 1080 patients with 1194 breast les...
journal_title:European journal of radiology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ejrad.2015.08.015
更新日期:2015-12-01 00:00:00
abstract:OBJECTIVE:A software program was developed simulating a compartmental model of blood circulation based on differential equations. The aim of this study was to compare software-simulated levels of hepatic enhancement with the true values in patients and to test how many patients reach the simulated hepatic enhancement l...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/S0720-048X(03)00217-1
更新日期:2004-07-01 00:00:00
abstract:PURPOSE:To evaluate reduction in inappropriate knee MRI requests following implementation of a mandatory knee MRI appropriateness checklist. METHODS:A retrospective review was performed at a single tertiary care centre. A knee MRI appropriateness checklist was developed based on the ACR Appropriateness Criteria and ad...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2019.108781
更新日期:2020-02-01 00:00:00
abstract:OBJECTIVE:Legionella pneumonia is usually classified as "atypical pneumonia", which suggests a predominance of interstitial patterns in chest X-rays. Based on a selection of recent clinical cases and a brief review of the literature, the aim of the study is to clarify, how far the actual radiological findings would be ...
journal_title:European journal of radiology
pub_type: 杂志文章,评审
doi:10.1016/j.ejrad.2006.08.020
更新日期:2007-01-01 00:00:00
abstract:AIM:The atrium septum is tilted in heart. There is an angle between atrium septum and the cross section of body, which is called tilt angles of atrium septum (TAAS) in this study, however this angle has not been specifically mentioned in literatures. In this article TAAS was measured and analysed on axial images of con...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2011.01.040
更新日期:2012-01-01 00:00:00
abstract::While urothelial carcinoma is a very common tumor, involvement of the upper tract is relatively uncommon. Consequently, there are no consensus imaging recommendations for upper tract disease. CT urography is the dominant imaging modality for the upper tract, but despite its excellent performance characteristics and be...
journal_title:European journal of radiology
pub_type: 杂志文章,评审
doi:10.1016/j.ejrad.2017.10.021
更新日期:2018-01-01 00:00:00
abstract:PURPOSE:To prospectively evaluate the diagnostic performance of 64-section multidetector computed tomography (MDCT) to detect significant coronary artery stenosis using conventional coronary angiography (CCA) as the reference standard. MATERIALS AND METHODS:Institutional Review Board approval and informed consent were...
journal_title:European journal of radiology
pub_type: 临床试验,杂志文章
doi:10.1016/j.ejrad.2007.01.009
更新日期:2007-06-01 00:00:00
abstract::Two unusual cases of xanthogranulomatous pyelonephritis studied by both magnetic resonance imaging and computed tomography, are presented. Extension of the disease depicted by both computed tomography and magnetic resonance imaging was compatible with the findings at surgery. Computed tomography seems to be sufficient...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/s0720-048x(97)00084-3
更新日期:1998-08-01 00:00:00
abstract::The ocular motor nerves (OMNs) comprise the oculomotor, trochlear and the abducens nerves. According to their course, they are divided into four or five anatomic segments: intra-axial, cisternal, cavernous and intra-orbital and, for the abducens nerve, an additional interdural segment. Magnetic resonance imaging is th...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2009.05.066
更新日期:2010-05-01 00:00:00
abstract:PURPOSE:Hemodynamic features associated with the bleeding from gastric fundal varices (FV) have not been fully examined. The purpose of this study was to elucidate hemodynamics in the short gastric vein (SGV) which is a major inflow route for FV and flow direction of the splenic vein (SV) in relation to bleeding FV. M...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2009.06.024
更新日期:2010-07-01 00:00:00
abstract:OBJECTIVES:To elucidate the utility of PROPELLER for motion artefact reduction on shoulder MRI and to examine the influence of streak artefacts on diagnosis of clinical images. METHODS:15 healthy volunteers and 48 patients underwent shoulder MRI with/without PROPELLER (coronal oblique proton density-fast spin echo [PD...
journal_title:European journal of radiology
pub_type: 临床试验,杂志文章
doi:10.1016/j.ejrad.2016.07.008
更新日期:2016-10-01 00:00:00
abstract:PURPOSE:To assess the dose-normalized iodine contrast-to-noise-ratio (CNRD) improvement and contrast media reduction potential obtained with photon-counting (PC) CT compared to conventional energy-integrating (EI) CT as a function of patient size and tube voltage. METHOD:Images of a semi-anthropomorphic phantom of dif...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2020.108909
更新日期:2020-05-01 00:00:00
abstract:PURPOSE:To evaluate if computed tomography (CT) coronary calcium scoring is needed after detection of coronary calcifications on conventional chest radiographs. MATERIALS AND METHODS:One hundred and five patients (67 men; 57.2+/-12.8 years) with suspected coronary artery disease underwent conventional chest radiograph...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2007.10.016
更新日期:2009-03-01 00:00:00
abstract:OBJECTIVES:To reveal the impact on workflow from introducing a dual-room sliding gantry CT to the trauma room for polytrauma and regularly scheduled in- outpatients with regard to efficiency and degree of capacity utilisation. MATERIALS AND METHODS:Time analysis was performed for 30 polytrauma patients each in 2 diffe...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2014.10.013
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVES:To reveal the contribution of MRI and diffusion-weighted imaging (DWI) to the diagnosis of mitochondrial encephalopathy (ME) and to evaluate the parenchymal changes associated with this disease in the involved parenchymal areas using the apparent diffusion coefficient (ADC) parameter. METHODS:Ten patients w...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2013.06.031
更新日期:2014-01-01 00:00:00
abstract::PACS has been widely adopted as an image storage solution that perfectly fits the radiology department workflow and that can be easily extended to other hospital departments. Integrations with other hospital systems, like the Radiology Information System, the Hospital Information System and the Electronic Patient Reco...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2010.05.026
更新日期:2011-05-01 00:00:00
abstract:OBJECTIVES:To investigate whether the evaluation of multiple spectral regions can increase the diagnostic performance of 1H-MRS of the breast and reduce false positive findings. METHODS:93 patients (mean age 56 years, range 23-79) undergoing breast MRI for routine clinical indications on a 1.5T scanner were eligible f...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2017.04.014
更新日期:2017-07-01 00:00:00
abstract:OBJECTIVE:To prospectively evaluate the diagnostic efficacy of conventional ultrasound (US), contrast-enhanced US (CEUS), the combined use of two modalities, and magnetic resonance imaging (MRI) in the differentiation of focal solid breast lesions. MATERIALS AND METHODS:61 patients with BI-RADS category 3-5 breast les...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2012.09.004
更新日期:2012-12-01 00:00:00
abstract:PURPOSE:The purpose of this cadaver study was to determine the ideal position of the wrist for scaphoid radiography. MATERIALS AND METHODS:Four cadaver wrists were rotated around their longitudinal axis in 15 degrees increments and exposures were taken. Seven postero-anterior images were taken as well. Thus, 18 images...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2007.02.008
更新日期:2007-10-01 00:00:00
abstract:OBJECTIVE:To assess virtual non-enhanced dual energy computed tomography (DECT) reconstruction as a potential alternative to true non-enhanced thoracic and abdominal CT scans in patients with suspected active hemorrhage. METHODS AND MATERIALS:Ninety-seven consecutive patients with suspected active bleeding, who underw...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2018.10.026
更新日期:2018-12-01 00:00:00
abstract:INTRODUCTION:To compare the diagnostic performance and inter-observer reproducibility of CT and MRI in detecting colorectal liver metastases (CRLM) of observers with different levels of experience. MATERIALS AND METHODS:Data from 51 CT and 54 MRI examinations of 105 patients with CRLM were analysed. Intraoperative and...
journal_title:European journal of radiology
pub_type: 杂志文章
doi:10.1016/j.ejrad.2014.07.005
更新日期:2014-10-01 00:00:00