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Detection of significant coronary artery stenosis with 64-section MDCT angiography.

Abstract：

PURPOSE:To prospectively evaluate the diagnostic performance of 64-section multidetector computed tomography (MDCT) to detect significant coronary artery stenosis using conventional coronary angiography (CCA) as the reference standard. MATERIALS AND METHODS:Institutional Review Board approval and informed consent were obtained. In this prospective study, 80 patients (61 male, 19 female, mean age 56) were examined. Sensitivity, specificity, positive (PPV) and negative predictive values (NPV) were calculated. McNemar test was used to search for the significant difference between 64-section MDCT angiography and CCA to detect stenosis. Also, kappa index (kappa) for the agreement between MDCT angiography and CCA was calculated. RESULTS:The sensitivity, specificity, positive (PPV) and negative predictive values (NPV) for detecting significant stenosis were 96%, 98%, 91%, 99%, respectively. The sensitivity, specificity, PPV and NPV for classification of patients with or without CAD were 100% for all. McNemar test demonstrated no significant difference between 64-section MDCT angiography and CCA. Also, kappa index (kappa) indicated excellent agreement. CONCLUSION:Sixty-four section MDCT angiography is an effective diagnostic tool for the detection of significant coronary artery stenosis. Especially, the potential to differentiate patients with and without CAD may provide MDCT an important role in the prevention of unnecessary invasive diagnostic procedures.

journal_name

Eur J Radiol

journal_title

European journal of radiology

authors

Oncel D,Oncel G,Tastan A,Tamci B

doi

10.1016/j.ejrad.2007.01.009

subject

Has Abstract

pub_date

2007-06-01 00:00:00

pages

394-405

issue

3

eissn

0720-048X

issn

1872-7727

pii

S0720-048X(07)00031-9

journal_volume

62

pub_type

临床试验,杂志文章

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