Demonstrating the effect of theophylline treatment on diaphragmatic movement in chronic obstructive pulmonary disease patients by MR-fluoroscopy.

Abstract:

INTRODUCTION:The purpose of this study was to determine the increase in diaphragmatic excursion of patients with chronic obstructive pulmonary disease (COPD) treated with theophylline by MR-fluoroscopy which is an innovative method to demonstrate effectiveness of this treatment. MATERIALS AND METHODS:Investigations were performed on a 0.3 T open MR unit. MR-fluoroscopy images of 30 patients with COPD were obtained before and after theophylline treatment. Diaphragmatic movement values were recorded for evaluation. RESULTS:The response of the diaphragmatic movement in COPD patients treated with theophylline was evaluated by MR-fluoroscopy and an increase of 48% in diaphragmatic contractility was determined after the treatment. The increase in contractility was found to be parallel with respiratory function tests and clinical status. CONCLUSION:Diaphragmatic movement and response to the medical therapy in patients with COPD can be evaluated by MR-fluoroscopy method which can allow accurate measurements.

journal_name

Eur J Radiol

authors

Etlik O,Sakarya ME,Uzun K,Harman M,Temizoz O,Durmus A

doi

10.1016/S0720-048X(03)00210-9

keywords:

subject

Has Abstract

pub_date

2004-08-01 00:00:00

pages

150-4

issue

2

eissn

0720-048X

issn

1872-7727

pii

S0720048X03002109

journal_volume

51

pub_type

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