[Corrigendum] MicroRNA-375 inhibits glioma cell proliferation and migration by downregulating RWDD3 in vitro.

abstract：:Breast cancer is the most common type of cancer among women worldwide. Research using breast cancer cell lines derived from primary tumors may provide valuable additional knowledge regarding this type of cancer. Therefore, the aim of this study was to investigate the phenotypic prof...

journal_title：Oncology reports

authors： Corrêa NC,Kuasne H,Faria JA,Seixas CC,Santos IG,Abreu FB,Nonogaki S,Rocha RM,Aparecida Borges Silva G,Gobbi H,Rogatto SR,Goes AM,Gomes DA

更新日期：2013-04-01 00:00:00

abstract：:Perylenequinones that generate reactive oxygen species (ROS) when illuminated with visible light have been recommended as photodynamic chemotherapeutic agents. One of these is calphostin C (CalC), the action of the photo-activated derivative of which, CalCphiE, has been ascribed to its ability to selectively and irrev...

journal_title：Oncology reports

authors： Chiarini A,Whitfield JF,Pacchiana R,Marconi M,Armato U,Dal Prà I

更新日期：2010-04-01 00:00:00

abstract：:Dendritic cell-mediated cancer immunotherapy employs several ways to engage tumor antigens. We have demonstrated in both pre-clinical animal studies and early clinical trials that dendritomas, highly purified hybrids between dendritic cells (DC) and tumor cells, are superior activators of anti-tumor immunity. It has b...

journal_title：Oncology reports

authors： Branham-O'Connor M,Li J,Kotturi HS,Yu X,Wagner TE,Wei Y

更新日期：2010-02-01 00:00:00

abstract：:Sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) 3 is involved in calcium mobilization from the endoplasmic reticulum into the cytosol and is closely linked to metabolism, neuronal plasticity, gene transcription, cell growth, differentiation, apoptosis, protein folding and carcinogenesis. In order to elucidate the role...

journal_title：Oncology reports

authors： Gou WF,Niu ZF,Zhao S,Takano Y,Zheng HC

更新日期：2014-01-01 00:00:00

abstract：:Hydrogen sulfide (H2S) participates in multifarious physiological and pathophysiologic progresses of cancer both in vitro and in vivo. We have previously demonstrated that exogenous H2S promoted liver cancer cells proliferation/anti‑apoptosis/angiogenesis/migration effects via amplifying the activation of NF-κB pathwa...

journal_title：Oncology reports

authors： Zhen Y,Zhang W,Liu C,He J,Lu Y,Guo R,Feng J,Zhang Y,Chen J

更新日期：2015-11-01 00:00:00

abstract：:Patients with hepatocellular carcinoma (HCC) have a poor prognosis, and novel molecular targets for treating recurrence and progression of the disease along with associated biomarkers are urgently required. In the present study, expression and the regulatory mechanism of TUSC1 (tumor suppressor candidate 1) were inves...

journal_title：Oncology reports

authors： Shimizu D,Kanda M,Nomoto S,Oya H,Takami H,Hibino S,Suenaga M,Inokawa Y,Hishida M,Takano N,Nishikawa Y,Yamada S,Fujii T,Nakayama G,Sugimoto H,Koike M,Fujiwara M,Kodera Y

更新日期：2014-03-01 00:00:00

abstract：:Aberrant nuclear factor-erythroid 2 (NRF2) expression correlates with tumor development. We investigated NRF2 expression in ovarian epithelial carcinoma (OEC), aiming to identify associations with clinicopathological factors, hormones and induced reactive oxygen species (ROS). Immun...

journal_title：Oncology reports

authors： Liao H,Zhou Q,Zhang Z,Wang Q,Sun Y,Yi X,Feng Y

更新日期：2012-06-01 00:00:00

abstract：:Telomerase activation is prevalent in most epithelial tumors, and may be a critical step in cellular immortalization and carcinogenesis. However, telomerase activity in tumors of mesenchymal origin is not well understood. In the present study, we examined telomerase activity in clinical samples from osteosarcoma and s...

journal_title：Oncology reports

authors： Terasaki T,Kyo S,Takakura M,Maida Y,Tsuchiya H,Tomita K,Inoue M

更新日期：2004-06-01 00:00:00

abstract：:Subsequently to the publication of this paper, the authors have realized that the affilitation address omitted the name of the university at which this research was conducted (Capital Medical University). Therefore, the author affiliations for this paper should have appeared as follows (changes are highlighted in bold...

journal_title：Oncology reports

authors： Dong J,Xu M

更新日期：2019-12-01 00:00:00

abstract：:The usefulness of the in vitro chemosensitivity test, the collagen gel droplet embedded culture drug- sensitivity test (CD-DST, Int J Oncol 11: 449, 1997), in cisplatin-based combined chemotherapy for postoperative recurrent tumors in non-small cell lung cancer (NSCLC) patients was retrospectively analyzed. CD-DST dat...

journal_title：Oncology reports

authors： Higashiyama M,Kodama K,Yokouchi H,Takami K,Nakagawa H,Imamura F,Minamigawa K,Kobayashi H

更新日期：2001-03-01 00:00:00

abstract：:Prostate cancer antigen 3 (PCA3) is a non-coding RNA fragment that is overexpressed in prostate cancer cells. However, the clinical applications of PCA3 are highly limited due to the instability of RNA and the lack of reliable and efficient RNA extraction and purification methods. Thus, in the present study, we compar...

journal_title：Oncology reports

authors： Zheng K,Dou Y,He L,Li H,Zhang Z,Chen Y,Ye A,Liu W,Kong L

更新日期：2015-11-01 00:00:00

abstract：:MicroRNA-1 (miR-1) has been shown to function as a critical gene regulator in multiple types of cancers. However, the role of miR-1 in osteosarcoma has not been totally clarified. In the present study, we investigated the effects of miR-1 on osteosarcoma and the underlying mechanism. We found that miR-1 was downregula...

journal_title：Oncology reports

authors： Jiang C,Chen H,Shao L,Wang Q

更新日期：2014-09-01 00:00:00

abstract：:We showed that the HER2/Grb2/Akt pathway induces all-trans retinoic acid (ATRA) resistance in breast cancer cells by suppressing the DNA binding activity of retinoic acid receptors (RAR). AP-1 activation was shown to induce ATRA resistance. Here, we determined whether AP-1 binding activity is correlated with ATRA resi...

journal_title：Oncology reports

authors： Mendoza-Gamboa E,Siwak DR,Tari AM

更新日期：2004-10-01 00:00:00

abstract：:Thymidine kinase-1 (TK-1) and thymidylate synthase (TS) are key enzymes for salvage and de novo pyrimidine synthesis, respectively. Numerous studies have suggested that increased TS levels are associated closely with resistance to fluoropyrimidine-based chemotherapy. TAS-102 is a novel drug containing trifluorothymidi...

journal_title：Oncology reports

authors： Shintani M,Urano M,Takakuwa Y,Kuroda M,Kamoshida S

更新日期：2010-05-01 00:00:00

abstract：:A phase I study of S-1 and biweekly docetaxel (DOC) combination therapy was conducted to determine the maximum tolerated dose (MTD) and pharmacokinetic parameters. Fourteen patients with advanced or recurrent gastric cancer were analyzed. The treatment consisted of S-1 [body surface area (BSA) <1.25 m2:80 mg/day, 1.25...

journal_title：Oncology reports

authors： Takahashi I,Emi Y,Kakeji Y,Tokunaga E,Ushiro S,Oki E,Watanabe M,Baba H,Maehara Y

更新日期：2006-04-01 00:00:00

abstract：:S-1 is an oral antitumor agent that contains tegafur, which is converted to fluorouracil (5-FU) in the human body. Cytochrome P450 2A6 (CYP2A6) is the principal enzyme responsible for bioconversion of tegafur to 5-FU. A number of CYP2A6 polymorphisms have been associated with variat...

journal_title：Oncology reports

authors： Fang WJ,Mou HB,Jin DZ,Zheng YL,Zhao P,Mao CY,Peng L,Huang MZ,Xu N

更新日期：2012-05-01 00:00:00

abstract：:In this study, we investigated the sequence variation and different transcriptional activities of the upstream regulatory region (URR) in HPV 16 E7 variants in cervical cancer tissue from Korean women. Using PCR-directed sequencing, the presence of sequence variations in URRs were analyzed and the sites of sequence va...

journal_title：Oncology reports

authors： Kim YB,Song YS,Jeon YT,Park JS,Um SJ,Kim JW,Park NH,Kang SB,Lee HP

更新日期：2005-08-01 00:00:00

abstract：:ETS‑domain containing protein (Elk1) is reported to be a member of the ETS oncogene family, and promotes tumorigenesis in cancer such as bladder, prostate and ovarian. Nevertheless, the role of Elk1 in thyroid cancer progression remains unclear. In the present study, we aimed to investigate the role and underlying mol...

journal_title：Oncology reports

authors： Kong Y,Yin J,Fu Y,Chen Y,Zhou Y,Geng X

更新日期：2018-09-01 00:00:00

abstract：:Aberrantly expressed miRNAs play a crucial role in the progression of lung adenocarcinoma. However, to date, the role of miR‑888 in lung adenocarcinoma progression is unclear. In the present study, the biological function of miR‑888 and its underlying mechanism in lung adenocarcinoma progression were explored. RT‑qPCR...

journal_title：Oncology reports

authors： Cao JX

更新日期：2019-06-01 00:00:00

abstract：:As part of the efforts to drug repurposing, some HIV drugs have recently been identified to exert anticancer effects. Selected nucleoside analogues of nucleosidic reverse-transcriptase inhibitors (NRTIs) have been shown to interfere with RNA transcription of HI viruses as well as with the replication of DNA in cancer ...

journal_title：Oncology reports

authors： Brüning A,Jückstock J,Kost B,Tsikouras P,Weissenbacher T,Mahner S,Mylonas I

更新日期：2017-01-01 00:00:00

abstract：:Reactive oxygen species (ROS) can drive the de‑differentiation of tumor cells leading to the process of epithelial-to-mesenchymal transition (EMT) to enhance invasion and metastasis. The invasive and metastatic phenotype of malignant cells is often linked to loss of E-cadherin expression, a hallmark of EMT. Recent stu...

journal_title：Oncology reports

authors： Wang Y,Ma J,Shen H,Wang C,Sun Y,Howell SB,Lin X

更新日期：2014-11-01 00:00:00

abstract：:Although chemotherapy is initially effective in debulking tumor mass in a number of different types of malignancy, tumor cells gradually acquire chemoresistance and frequently progress to advanced clinical stage. Accumulating evidence has indicated that the tumor sensitivity to several chemotherapeutic drugs is regula...

journal_title：Oncology reports

authors： Tomita R,Sasabe E,Tomomura A,Yamamoto T

更新日期：2020-11-01 00:00:00

abstract：:Neoadjuvant chemotherapy is often used in the treatment of advanced esophageal cancer. In this study, we determined the impact of chemotherapy on microRNA (miRNA) expression in esophageal cancer cells, and whether identified changes might have biological relevance. Two esophageal carcinoma cell lines (one adenocarcino...

journal_title：Oncology reports

authors： Hummel R,Wang T,Watson DI,Michael MZ,Van der Hoek M,Haier J,Hussey DJ

更新日期：2011-10-01 00:00:00

abstract：:Telomerase is a ribonucleoprotein enzyme which is endogenously expressed in germ, stem and tumor cells, but absent in benign somatic cells. The two major telomerase components are human telomerase RNA (hTR) and human telomerase reverse transcriptase (hTERT). It has been shown that hTERT is rate-limiting for telomerase...

journal_title：Oncology reports

authors： Schrader M,Burger AM,Müller M,Krause H,Straub B,Smith GL,Newlands ES,Miller K

更新日期：2002-09-01 00:00:00

abstract：:Histone deacetylases (HDACs) have been shown to play important roles in the regulation of chromatin remodeling by histone deacetylation, and their expression is induced in several types of cancer. In addition, they are known to be associated with resistance to anticancer drugs. However, the relevance of HDAC4 in chemo...

journal_title：Oncology reports

authors： Yu SL,Lee DC,Son JW,Park CG,Lee HY,Kang J

更新日期：2013-09-01 00:00:00

abstract：:The aims of the present study were to review the experience of different surgical reconstruction methods for hypopharyngeal squamous cell carcinoma (HSCC) and compared the survival of patients with and without laryngeal function (LF) preservation. The clinical characteristics of 580 patients were retrospectively obtai...

journal_title：Oncology reports

authors： Zhou J,Li Y,Wei D,Qian Y,Li W,Liu D,Li G,Pan X,Lei D

更新日期：2015-12-01 00:00:00

abstract：:Intratumoral regions of low extracellular pH and low nutrition are common features of solid tumors. Although cancer cells normally die when they are removed from their environment, a small population of cells survive. In the present study, the subline LNCaP-F10, of the prostate canc...

journal_title：Oncology reports

authors： Iguchi K,Hayakawa Y,Ishii K,Matsumoto K,Usui S,Sugimura Y,Hirano K

更新日期：2012-12-01 00:00:00

abstract：:microRNAs (miRNAs), a class of small non-coding RNA molecules, can regulate gene expression by interacting with the 3'-untranslated regions (3'UTR) of target genes and influence various biological processes. We investigated the potential role of miR-24-3p in the development of bladder cancer by regulating DEDD, a memb...

journal_title：Oncology reports

authors： Yu G,Jia Z,Dou Z

更新日期：2017-02-01 00:00:00

abstract：:The usefulness of diagnostic ultrasound in gene transfer was investigated. The hepatocellular carcinoma cell lines PRL/PRF/5 and Hep3B, and the pancreatic carcinoma Panc-1 cells were transfected with lipofectin or irradiated with a linear probe with a frequency of 8 MHz at a mechani...

journal_title：Oncology reports

authors： Tomizawa M,Shinozaki F,Sugiyama T,Yamamoto S,Sueishi M,Yoshida T

更新日期：2012-05-01 00:00:00

abstract：:We conducted a clinical pharmacological evaluation of paclitaxel/carboplatin combination in Japanese patients with non-small cell lung cancer. The purpose of this study was to identify the optimal dose of this combination and to investigate the relationships between the pharmacokinetic profiles of these 2 drugs, serum...

journal_title：Oncology reports

authors： Daga H,Isobe T,Miyazaki M,Fujitaka K,Kondo K,Kohno N

更新日期：2004-06-01 00:00:00