Overall survival with and without laryngeal function preservation in 580 patients with hypopharyngeal squamous cell carcinoma.

Abstract:

:The aims of the present study were to review the experience of different surgical reconstruction methods for hypopharyngeal squamous cell carcinoma (HSCC) and compared the survival of patients with and without laryngeal function (LF) preservation. The clinical characteristics of 580 patients were retrospectively obtained and analyzed. Survival curves were analyzed using the Kaplan‑Meier method for survival and Cox models for hazard ratios (HRs) with 95% confidence intervals (CIs). LF was preserved in 403 cases and not preserved in 177 cases. The 3‑ and 5‑year survival rates were 70.9 and 52.7%, respectively, in the LF preservation group and 48.4 and 30.5%, respectively, in the no LF preservation group. Compared with the patients without LF preservation, patients with LF preservation had a significantly reduced risk of overall death (HR=0.63, 95% CI: 0.50-0.80). LF preservation positively affects the prognosis of patients with HSCC.

journal_name

Oncol Rep

journal_title

Oncology reports

authors

Zhou J,Li Y,Wei D,Qian Y,Li W,Liu D,Li G,Pan X,Lei D

doi

10.3892/or.2015.4313

subject

Has Abstract

pub_date

2015-12-01 00:00:00

pages

3196-202

issue

6

eissn

1021-335X

issn

1791-2431

journal_volume

34

pub_type

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