Abstract:
:Actin and non-muscle myosins have long been known to play important roles in growth cone steering and neurite outgrowth. More recently, novel functions for non-muscle myosin have been described in axons and dendritic spines. Consequently, possible roles of actomyosin contraction in organizing and maintaining structural properties of dendritic spines, the size and location of axon initial segment and axonal diameter are emerging research topics. In this review, we aim to summarize recent findings involving myosin localization and function in these compartments and to discuss possible roles for actomyosin in their function and the signaling pathways that control them.
journal_name
Cellsjournal_title
Cellsauthors
Mikhaylova M,Rentsch J,Ewers Hdoi
10.3390/cells9092006subject
Has Abstractpub_date
2020-09-01 00:00:00issue
9issn
2073-4409pii
cells9092006journal_volume
9pub_type
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