Abstract:
:An intraocular biopsy is performed for diagnostic, prognostic and investigational purposes. Biopsies help to confirm or exclude malignancies and differentiate inflammatory from infectious processes. Histopathological analysis is the final verdict in unresponsive uveitis, atypical inflammation, metastases and masquerade syndromes. Advances and refinement of techniques in cytopathology, immunohistochemistry, microbiological and molecular biologic study offer much more than just diagnosis. They provide prognosis based on cell characteristics and are helpful in planning treatment and intervention. Many biopsy procedures have evolved to provide more safety and minimise complications thus improving the quality of specimens or samples available for analysis. The type of biopsy and technique adopted varies based on the clinical suspicion, size and location of lesions. In uveitis, a working diagnosis of intraocular inflammation is made on clinical examination and laboratory investigations and ancillary tests. Malignancy and uveitis is interlinked and masquerade syndromes are among the commonest indications for biopsy and analysis of specimen. The various types of intraocular biopsies include aqueous tap, fine needle aspiration biopsy, vitreous biopsy, iris and ciliary body, and retinochoroidal biopsy. They will be reviewed in this article with respect to current perspective.
journal_name
Indian J Ophthalmoljournal_title
Indian journal of ophthalmologyauthors
Patnaik G,Annamalai R,Biswas Jdoi
10.4103/ijo.IJO_1325_20subject
Has Abstractpub_date
2020-09-01 00:00:00pages
1838-1843issue
9eissn
0301-4738issn
1998-3689pii
IndianJOphthalmol_2020_68_9_1838_292520journal_volume
68pub_type
杂志文章,评审abstract::Midbrain hemorrhage causing isolated fourth nerve palsy is extremely rare. Idiopathic, traumatic and congenital abnormalities are the most common causes of fourth nerve palsy. We report acute isolated fourth nerve palsy in an 18-year-old lady due to a midbrain hemorrhage probably due to a midbrain cavernoma. The case ...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.58476
更新日期:2010-01-01 00:00:00
abstract::Iris cyst excision involves complex surgical maneuvers and may have a variable visual outcome depending upon preexisting and postoperative complications. Hereby, we report a case series of 10 eyes from which posttraumatic iris cysts were excised and proven histopathologically. Histopathology records were reviewed. Dat...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.43383
更新日期:2008-11-01 00:00:00
abstract::Thelazia callipaeda or the oriental eye worm infects a wide variety of hosts including dogs, cats, foxes, rabbits, and humans through the Drosophila flies. We report here a case of a 42-year-old female who presented with pain, redness, and cystic swelling in the right lacrimal sac area for 8 months. Ocular examination...
journal_title:Indian journal of ophthalmology
pub_type:
doi:10.4103/ijo.IJO_317_18
更新日期:2018-08-01 00:00:00
abstract:Purpose:To validate the smartphone photography as a screening tool for amblyogenic conditions in children. Methods:Children between 5 to 8 years attending eye out patient department (OPD) were photographed (by an optometrist) with a smartphone to capture their pupillary red reflexes followed by clinical examination by...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_2090_18
更新日期:2019-10-01 00:00:00
abstract:BACKGROUND AND AIM:Central corneal thickness (CCT) of term and preterm infants in Indian population is not known. We did a prospective noninterventional study to measure the CCT in term and preterm infants. MATERIALS AND METHODS:An ultrasonic pachymeter was used. The data regarding the date of birth, expected date of ...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.162601
更新日期:2015-06-01 00:00:00
abstract:PURPOSE:The purpose of this study is to evaluate the safety and benefits of immediate sequential bilateral cataract surgery. PATIENTS AND METHODS:Retrospective data analysis of patients who underwent immediate sequential bilateral phacoemulsification with foldable intraocular lens (IOL) implantation under topical anes...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_947_16
更新日期:2017-05-01 00:00:00
abstract::Tumours arising in the sweat glands of the eyelids are rare. A case of Eccrine Acrospiroma, otherwise, called clear cell hidradenoma, a benign sweat gland tumour of the lid in a female aged 70 years is being reported because of its rarity. ...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1990-10-01 00:00:00
abstract::A 60-year-old man presented with sudden-onset proptosis of the left eye and intermittent diplopia of 2 months duration. Ophthalmic examination revealed bilateral eyelid retraction, left eye proptosis and a firm, non-tender mass (2 cm × 1.5 cm) in left supero-medial orbit with restricted extraocular movements. Contrast...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_1699_18
更新日期:2019-08-01 00:00:00
abstract:Purpose:To study the efficiency of vitamin D3 (buccal spray) alone and combination of vitamin D3 with cyclosporine in the treatment of dry eye disease (DED) in patients with deficient serum 25(OH)D levels. Methods:Around 90 patients with DED with deficient serum 25(OH)D levels were included and randomized into three g...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_1492_19
更新日期:2020-06-01 00:00:00
abstract::Gene therapy is a novel form of drug delivery that enlists the synthetic machinery of the patient's cells to produce a therapeutic agent. Genes may be delivered into cells in vitro or in vivo utilising viral or non-viral vectors. Recent technical advances have led to the demonstration of the molecular basis of various...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章,评审
doi:
更新日期:2002-09-01 00:00:00
abstract:Purpose:To use the extent of retinal immaturity at the first visit to predict progression to any stage and treatment-requiring retinopathy of prematurity (ROP). Methods:Retrospective, multicenter, nonrandomized, observational, clinical, validation study. In all, 601 Asian Indian preterm infants born < 2000 g and/or < ...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.4103/ijo.IJO_469_19
更新日期:2019-06-01 00:00:00
abstract::Retinal racemose hemangiomas (RRH) are vascular malformations comprising of direct arteriovenous communications in the retina. Exudation and neurosensory detachment are some of the complications which may cause decreased visual acuity. Herein, we describe a case of a 38-year-old male presenting with unilateral Group I...
journal_title:Indian journal of ophthalmology
pub_type:
doi:10.4103/ijo.IJO_293_20
更新日期:2020-10-01 00:00:00
abstract::Postoperative endophthalmitis is a serious, vision-threatening complication of intraocular surgery. Better instrumentation, surgical techniques, prophylactic antibiotics and better understanding of asepsis have significantly reduced the incidence of this complication. Postoperative endophthalmitis may occur as an isol...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章,评审
doi:
更新日期:2001-03-01 00:00:00
abstract::Information technology has had a tremendous impact on the outlook of our professional lives. The Internet has revolutionised the speed of access to information with touch of a button. This article discusses the various aspects of information technology which are changing and enhancing our professional lives. It provid...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章,评审
doi:
更新日期:2000-09-01 00:00:00
abstract::We report a case of necrotizing scleritis following diode cyclo-photocoagulation (CPC). A-64-year-old-Asian Indian male presented with pseudophakic corneal decompensation with secondary angle closure glaucoma that was uncontrolled with maximum medical therapy. Trans-scleral diode CPC was performed in the inferior 180-...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.27074
更新日期:2006-09-01 00:00:00
abstract::[This corrects the article DOI: 10.4103/0301-4738.171956.]. ...
journal_title:Indian journal of ophthalmology
pub_type: 已发布勘误
doi:10.4103/0301-4738.214668
更新日期:2017-09-01 00:00:00
abstract::Susac syndrome (SS) is a rare retinal-cochlear-cerebral disease with an unclear etiology. A 35-year-old man presented with sudden painless vision loss in the right eye and 2 months later in the left eye with hemiparesis, behavioral changes, and hearing loss. Ophthalmic examinations revealed multiple branch retinal art...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.194334
更新日期:2016-09-01 00:00:00
abstract:UNLABELLED:The authors here describe manual small incision cataract surgery (MSICS) by using topical anesthesia with intracameral 0.5% lignocaine, which eliminates the hazards of local anesthesia, cuts down cost and time taken for the administration of local anesthesia. AIMS:To evaluate the patients' and surgeons' exp...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.44488
更新日期:2009-01-01 00:00:00
abstract:Purpose:The purpose of the study is to report the outcomes of simultaneous cataract extraction (CE) and a new nonvalved glaucoma drainage device (GDD), Aurolab Aqueous Drainage Implant (AADI), in eyes with cataract and refractory glaucoma. Methods:This was a non-comparative, interventional, retrospective study. Consec...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_195_18
更新日期:2018-09-01 00:00:00
abstract::A prospective randomized clinical trial was carried out to compare the intercapsular or the endocapsular technique of IOL insertion and conventional posterior chamber IOL insertion after can opener capsulotomy. Age and sex matched groups of 76 patients each underwent surgery by the two techniques. The corneal and the ...
journal_title:Indian journal of ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1991-04-01 00:00:00
abstract:BACKGROUND:Recent reports indicated that the slope of the foveal depression influences the macular pigment (MP) spatial profile. MP has been shown to confer possible protection against age-related macular degeneration (ARMD) because of its antioxidant properties. AIMS:To study the configuration of foveal slope and the f...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.119437
更新日期:2013-09-01 00:00:00
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journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.81993
更新日期:2011-07-01 00:00:00
abstract:Purpose:The aim of this study was to compare the visual outcome of participants undergoing toric intraocular lens (IOL) implantation after cataract extraction using manual marking versus digital marking for intraoperative guidance. Methods:Randomized controlled trial of participants with cataract and corneal astigmati...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_465_20
更新日期:2020-12-01 00:00:00
abstract::The aim of the study was to compare the central corneal thickness (CCT), intraocular pressure (IOP), and tear insulin-like growth factor-1 (IGF-1) levels of 2 patients with acromegaly before and after the surgical treatment of the disease. CCTs, IOP levels, and tear IGF-1 values showed a decrease after the treatment i...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.170984
更新日期:2015-09-01 00:00:00
abstract::Dissociated vertical deviation (DVD) is an intermittent anomaly of the non-fixing eye. Although association of DVD with sensory visual deprivation owing to congenital or acquired opacities of the ocular media has been reported, its association with congenital hereditary endothelial dystrophy (CHED) has not been report...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.21614
更新日期:2006-03-01 00:00:00
abstract:Purpose:The purpose of this prospective experimental study was to evaluate the safety/toxicity of α4β1 integrin blockade in rabbit retina using its monoclonal antibody (Natalizumab). Methods:Twelve New Zealand albino rabbits were divided into three groups (n = 4). Unilateral intravitreal injections of three different ...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_425_18
更新日期:2018-10-01 00:00:00
abstract::"There are many classifications of xerophthalmia in existence. In the present study all these classification have been exhaustively reviewed. Many objections to previous classifications have been raised following experiences with these classifications for over six years. Based on these objections a self explanatory, e...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1991-07-01 00:00:00
abstract::As all developed countries are struggling with health care costs growing too large and too fast, the current performance and overburden of glaucoma services demand a reappraisal of current management strategies. The performance of the glaucoma care in western countries offers several opportunities to improve the simul...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/0301-4738.73684
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Platelets are an elective site for oxidative stress owing to their high content of polyunsaturated fatty acid. Increased lipid peroxidation and elevated platelet thiobarbituric acid-reacting substances (TBARS) signal oxidative stress. This possibly leads to retinal neovascularization in Eales' disease. METH...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:2000-12-01 00:00:00
abstract:Purpose:To analyze applications for blindness certificates to find causes of visual impairment (VI), handicap, and blindness in a tertiary hospital of Bihar. Methods:Applications for blindness certificates were analyzed over a two-year period. The main cause of blindness, visual handicap, and VI in these applications ...
journal_title:Indian journal of ophthalmology
pub_type: 杂志文章
doi:10.4103/ijo.IJO_837_18
更新日期:2019-02-01 00:00:00