Effectiveness and safety of vedolizumab in biologically naïve patients: A real-world multi-centre study.

abstract：:Fistulas and fibrosis or strictures represent frequent complications in irritable bowel disease (IBD) patients. To date, treatment options for fistulas are limited and surgery is often required. Similarly, no preventive treatment for fibrosis and stricture formation has been established. Frequently, stricture formatio...

journal_title：United European gastroenterology journal

authors： Scharl M,Bruckner RS,Rogler G

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Although screening colonoscopy is effective for early detection of colorectal cancer (CRC), screening rates remain low. Multiple factors are thought to be responsible for the low rates of screening colonoscopy, but bowel preparation appears to be a key deterrent. Tolerability issues with bowel preparations m...

journal_title：United European gastroenterology journal

authors： Moshkowitz M,Fokra A,Itzhak Y,Arber N,Santo E

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Patients with Crohn's disease (CD) frequently complain of cognitive difficulties such as problems with concentration and clouding of thought, yet this has scarcely been objectively defined and underlying mechanisms remain unknown. OBJECTIVE:The objective of this article is to objectively measure cognitive i...

journal_title：United European gastroenterology journal

authors： van Langenberg DR,Yelland GW,Robinson SR,Gibson PR

更新日期：2017-06-01 00:00:00

abstract：Background:Antibiotic-associated colitis caused by Clostridium difficile (C. difficile) is the most common cause of hospital-acquired diarrhea. The pathogenesis of C. difficile colitis is mediated by bacterial toxins. C. difficile infection (CDI) severity may be determined by the fecal level of these toxins. Objective...

journal_title：United European gastroenterology journal

authors： Cohen NA,Miller T,Na'aminh W,Hod K,Adler A,Cohen D,Guzner-Gur H,Santo E,Halpern Z,Carmeli Y,Maharshak N

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND AND AIMS:The aim of this study was to determine the mortality and re-bleeding rates, and the risk factors involved, in a cohort of patients with previous diverticular bleeding (DB). METHODS:In 2007, data on 2462 patients with lower gastrointestinal (GI) bleeding were collected prospectively at several Frenc...

journal_title：United European gastroenterology journal

authors： Lorenzo D,Gallois C,Lahmek P,Lesgourgues B,Champion C,Charpignon C,Faroux R,Bour B,Remy AJ,Naouri C,Picon M,Poncin E,Macaigne G,Seyrig JA,Bernardini D,Bellaïche G,Grasset D,Henrion J,Heluwaert F,Piperaud R,Bordes

更新日期：2017-02-01 00:00:00

abstract：Background:The diagnostic yield of coeliac disease could be improved by screening in at-risk groups, but long-term benefits of this approach are obscure. Objective:To investigate health, quality of life and dietary adherence in adult coeliac patients diagnosed in childhood by screening. Methods:After thorough evaluat...

journal_title：United European gastroenterology journal

authors： Kivelä L,Popp A,Arvola T,Huhtala H,Kaukinen K,Kurppa K

更新日期：2018-08-01 00:00:00

abstract：Background and objective:Psychological states may interfere with visceral sensitivity. Here we investigate associations between psychosocial factors and visceral sensitivity in irritable bowel syndrome (IBS). Methods:Two IBS patient cohorts (Cohort 1: n = 231, Rome II; Cohort 2: n = 141, Rome III) underwent rectal bar...

journal_title：United European gastroenterology journal

authors： Grinsvall C,Törnblom H,Tack J,Van Oudenhove L,Simrén M

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND AND AIM:The efficacy of clipping for preventing delayed bleeding after colorectal endoscopic resection is still controversial. To assess the efficacy of prophylactic clipping, we conducted a meta-analysis of randomized controlled trials. METHODS:We searched PubMed, the Cochrane library, and the Igaku-chuo-z...

journal_title：United European gastroenterology journal

authors： Nishizawa T,Suzuki H,Goto O,Ogata H,Kanai T,Yahagi N

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Underwater endoscopic mucosal resection without submucosal injection has been described for removing large flat colorectal lesions. OBJECTIVE:We aim to evaluate the reproducibility of this technique in terms of ease of implementation, safety and efficacy. METHODS:A prospective observational study of consec...

journal_title：United European gastroenterology journal

authors： Amato A,Radaelli F,Spinzi G

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Detection of cholangiocarcinoma (CC) remains a diagnostic challenge particularly in patients with primary sclerosing cholangitis (PSC). We recently established diagnostic peptide marker models in bile and urine to detect CC. Our aim was to combine both models to reach a higher diagnostic accuracy of CC diagn...

journal_title：United European gastroenterology journal

authors： Voigtländer T,Metzger J,Schönemeier B,Jäger M,Mischak H,Manns MP,Lankisch TO

更新日期：2017-08-01 00:00:00

abstract：Introduction:Fecal microbiota transfer (FMT) is highly effective in the treatment and prevention of recurrent Clostridioides difficile infection (rCDI) with cure rates of about 80% after a single treatment. Nevertheless, the reasons for failure in the remaining 20% remain largely elusive. The aim of the present study w...

journal_title：United European gastroenterology journal

authors： Peri R,Aguilar RC,Tüffers K,Erhardt A,Link A,Ehlermann P,Angeli W,Frank T,Storr M,Glück T,Sturm A,Rosien U,Tacke F,Bachmann O,Solbach P,Stallmach A,Goeser F,Vehreschild MJ,German Clinical Microbiome Study Group (GCMSG

更新日期：2019-06-01 00:00:00

abstract：INTRODUCTION:Because of their many advantages, faecal immunochemical tests (FIT) are superseding traditional guaiac-based faecal occult blood tests in bowel screening programmes. METHODS:A quantitative FIT was adopted for use in two evaluation National Health Service (NHS) Boards in Scotland using a cut-off faecal hae...

journal_title：United European gastroenterology journal

authors： Steele RJ,McDonald PJ,Digby J,Brownlee L,Strachan JA,Libby G,McClements PL,Birrell J,Carey FA,Diament RH,Balsitis M,Fraser CG

更新日期：2013-06-01 00:00:00

abstract：Background:Over the past decades, multiple approaches to aspiration sclerotherapy of large symptomatic hepatic cysts have been investigated. However, comparative data are scarce. Objective:The objective of this article is to compare cyst reduction, symptomatic relief, and adverse events between ethanol sclerotherapy a...

journal_title：United European gastroenterology journal

authors： Wijnands TF,Schoenemeier B,Potthoff A,Gevers TJ,Groenewoud H,Gebel MJ,Rifai K,Manns MP,Drenth JP

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:One of the aims of the Young Talent Group (YTG) is to make United European Gastroenterology (UEG) more attractive to young fellows interested in gastroenterology (GI), and to actively involve them in UEG activities and the activities of their respective national societies. In 2017, we conducted a survey amon...

journal_title：United European gastroenterology journal

authors： Heinrich H,Rodríguez-Lago I,Nakov R,Skuja V,Acedo P,Nitsche U,Mikolasevic I,van Herwaarden Y

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The 2016, United European Gastroenterology evidence-based guidelines for the diagnosis and therapy of chronic pancreatitis (HaPanEU) provided evidence-based recommendations for the management of chronic pancreatitis and allowed for the objective evaluation of the quality of care in several doma...

journal_title：United European gastroenterology journal

authors： de Rijk FE,Kempeneers MA,Bruno MJ,Besselink MG,van Goor H,Boermeester MA,van Geenen EJ,van Hooft JE,van Santvoort HC,Verdonk RC,Dutch Pancreatitis Study Group.

更新日期：2020-08-01 00:00:00

abstract：Background:Pancreatic function testing and imaging are used to inform the diagnosis of chronic pancreatitis, but most of these methods are time- and cost-consuming or lack diagnostic accuracy. Objective:We investigated the utility of pancreas-specific plasma amylase for assessment and diagnosis of chronic pancreatitis...

journal_title：United European gastroenterology journal

authors： Olesen SS,Krarup H,Poulsen JL,Christensen JH,Sheel ARG,Sutton R,Greenhalf W,Halloran C,Drewes AM

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Patients with primary oesophageal squamous cell carcinoma are at risk of developing multiple primary tumours in the upper aero digestive tract. To date, most studies are performed in the Asian population. We aimed to evaluate the risk of multiple primary tumours in the upper aero digestive tract and stomach ...

journal_title：United European gastroenterology journal

authors： van de Ven SE,Falger JM,Verhoeven RH,Baatenburg de Jong RJ,Spaander MC,Bruno MJ,Koch AD

更新日期：2020-12-03 00:00:00

abstract：OBJECTIVES:Malignant vascular tumors of the liver are rare. The aim of this study was to investigate the applicability of gray scale and contrast-enhanced ultrasonography in patients with epithelioid hemangioendothelioma (EHE) of the liver and hepatic angiosarcoma (HA) and to describe the clinical presentation. METHOD...

journal_title：United European gastroenterology journal

authors： Schweitzer N,Soudah B,Gebel M,Manns MP,Boozari B

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Women conceiving following in vitro fertilization (IVF) likely have a variety of risk factors that predispose them to gastroesophageal reflux disease (GERD) in the future. OBJECTIVE:We aimed to investigate whether pregnancy through IVF may predispose to subsequent GERD compared with pregnancies without IVF....

journal_title：United European gastroenterology journal

authors： Turan I,Kitapcioglu G,Tavmergen Goker E,Sahin G,Bor S,Ege Reflux Study Group.

更新日期：2016-04-01 00:00:00

abstract：:The European Society of Gastrointestinal Endoscopy (ESGE) and United European Gastroenterology (UEG) have a vision to create a thriving community of endoscopy services across Europe, collaborating with each other to provide high quality, safe, accurate, patient-centered and accessible endoscopic care. Whilst the bound...

journal_title：United European gastroenterology journal

authors： Rutter MD,Senore C,Bisschops R,Domagk D,Valori R,Kaminski MF,Spada C,Bretthauer M,Bennett C,Bellisario C,Minozzi S,Hassan C,Rees C,Dinis-Ribeiro M,Hucl T,Ponchon T,Aabakken L,Fockens P

更新日期：2016-02-01 00:00:00

abstract：Background:Since introduction of the MELD score in the liver allograft allocation system, renal insufficiency has emerged as an increasing problem. Here we evaluated the course of kidney function in patients with advanced renal insufficiency prior to liver transplantation (LT). Methods:A total of 254 patients undergoi...

journal_title：United European gastroenterology journal

authors： Horvatits T,Pischke S,Proske VM,Fischer L,Scheidat S,Thaiss F,Fuhrmann V,Lohse AW,Nashan B,Sterneck M

更新日期：2018-02-01 00:00:00

abstract：Background:Transient elastography is a non-invasive tool which can stratify patients at risk of chronic liver disease. However, a raised body mass index has been independently associated with a failed or unreliable examination. Objective:The purpose of this study was to analyse the performance of two probes (M/XL) on ...

journal_title：United European gastroenterology journal

authors： Harris R,Card TR,Delahooke T,Aithal GP,Guha IN

更新日期：2018-11-01 00:00:00

abstract：:Eosinophilic esophagitis (EoE) is an emerging esophageal inflammatory disorder affecting children and young adults. As a relatively new disease, EoE is still burdened by frequent diagnostic and therapeutic pitfalls in clinical practice. This manuscript posits a number of similarities with Crohn's disease, which may he...

journal_title：United European gastroenterology journal

authors： Molina-Infante J,Schoepfer AM,Lucendo AJ,Dellon ES

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Acute abdominal pain (AAP) is one of the most common causes of referral to an emergency department (ED), but information about its impact is limited. OBJECTIVES:The objectives of this article are to define the prevalence of AAP among ED visits in a large university hospital and analyze its main clinical fea...

journal_title：United European gastroenterology journal

authors： Caporale N,Morselli-Labate AM,Nardi E,Cogliandro R,Cavazza M,Stanghellini V

更新日期：2016-04-01 00:00:00

abstract：Background:Hepatorenal syndrome (HRS) is associated with a poor prognosis. In HRS type 1, loss of renal function is rapidly progressive, while HRS type 2 is characterised by chronic ascites and more moderately elevated renal parameters. While treatment with terlipressin/albumin is well established in type 1, its effect...

journal_title：United European gastroenterology journal

authors： Nguyen-Tat M,Jäger J,Rey JW,Nagel M,Labenz C,Wörns MA,Galle PR,Marquardt JU

更新日期：2019-05-01 00:00:00

abstract：Background:Hepatic encephalopathy is associated with altered gut microbiota. Proton pump inhibitors increase the risk of small bowel bacterial overgrowth. Objectives:This was a case-control study aimed at exploring the relationship of proton pump inhibitor use with the risk of hepatic encephalopathy during hospitaliza...

journal_title：United European gastroenterology journal

authors： Zhu J,Qi X,Yu H,Yoshida EM,Mendez-Sanchez N,Zhang X,Wang R,Deng H,Li J,Han D,Guo X

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to investigate the impact of obesity on disease activity and disease outcome in patients with inflammatory bowel disease. PATIENTS AND METHODS:The impact of obesity on inflammatory bowel disease disease activity and outcome was retrospectively assessed in 3075 patients enrolled ...

journal_title：United European gastroenterology journal

authors： Greuter T,Porchet F,Braga-Neto MB,Rossel JB,Biedermann L,Schreiner P,Scharl M,Schoepfer AM,Safroneeva E,Straumann A,Rogler G,Vavricka SR

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Recent reports from western countries have indicated an increased incidence and a decreased mortality in acute pancreatitis. However, the incidence assessment has often been hampered by the inclusion of both first-time and recurrent episodes of acute pancreatitis. METHODS:In this retrospective cohort study,...

journal_title：United European gastroenterology journal

authors： Oskarsson V,Hosseini S,Discacciati A,Videhult P,Jans A,Ekbom A,Sadr-Azodi O

更新日期：2020-05-01 00:00:00

abstract：:Crohn's disease (CD) is a chronic inflammatory bowel disease that usually progresses to bowel damage, defined as strictures, fistulas and abscesses. These complications require intestinal resection and lead to further irreversible structural damage. Cross-sectional imaging, such as magnetic resonance imaging, computed...

journal_title：United European gastroenterology journal

authors： Fiorino G,Bonifacio C,Allocca M,Danese S

更新日期：2020-05-01 00:00:00

abstract：Introduction:Endoscopic mucosal resection and endoscopic submucosal dissection are demanding procedures. This study aims to establish face, content and expert validity of the live porcine model in performing endoscopic mucosal resection, endoscopic submucosal dissection, complication management and to assess it as a tr...

journal_title：United European gastroenterology journal

authors： Küttner-Magalhães R,Dinis-Ribeiro M,Bruno MJ,Marcos-Pinto R,Rolanda C,Koch AD

更新日期：2018-05-01 00:00:00