Long-term health and treatment outcomes in adult coeliac disease patients diagnosed by screening in childhood.

Abstract:

Background:The diagnostic yield of coeliac disease could be improved by screening in at-risk groups, but long-term benefits of this approach are obscure. Objective:To investigate health, quality of life and dietary adherence in adult coeliac patients diagnosed in childhood by screening. Methods:After thorough evaluation of medical history, follow-up questionnaires were sent to 559 adults with a childhood coeliac disease diagnosis. The results were compared between screen-detected and clinically-detected patients, and also between originally asymptomatic and symptomatic screen-detected patients. Results:In total, 236 (42%) patients completed the questionnaires a median of 18.5 years after childhood diagnosis. Screen-detected patients (n = 48) had coeliac disease in the family and type 1 diabetes more often, and were less often smokers and members of coeliac societies compared to clinically-detected patients, whereas the groups did not differ in current self-experienced health or health concerns, quality of life or dietary adherence. Screen-detected, originally asymptomatic patients had more anxiety than those presenting with symptoms, whereas the subgroups were comparable in other current characteristics. Conclusion:Comparable long-term outcomes between screen-detected and clinically-detected patients support risk-group screening for coeliac disease. However, asymptomatic patients may require special attention.

authors

Kivelä L,Popp A,Arvola T,Huhtala H,Kaukinen K,Kurppa K

doi

10.1177/2050640618778386

subject

Has Abstract

pub_date

2018-08-01 00:00:00

pages

1022-1031

issue

7

eissn

2050-6406

issn

2050-6414

pii

10.1177_2050640618778386

journal_volume

6

pub_type

杂志文章
  • Middle-term mortality and re-bleeding after initial diverticular bleeding: A nationwide study of 365 mostly elderly French patients.

    abstract:BACKGROUND AND AIMS:The aim of this study was to determine the mortality and re-bleeding rates, and the risk factors involved, in a cohort of patients with previous diverticular bleeding (DB). METHODS:In 2007, data on 2462 patients with lower gastrointestinal (GI) bleeding were collected prospectively at several Frenc...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640616647816

    authors: Lorenzo D,Gallois C,Lahmek P,Lesgourgues B,Champion C,Charpignon C,Faroux R,Bour B,Remy AJ,Naouri C,Picon M,Poncin E,Macaigne G,Seyrig JA,Bernardini D,Bellaïche G,Grasset D,Henrion J,Heluwaert F,Piperaud R,Bordes

    更新日期:2017-02-01 00:00:00

  • European Society for the Study of Coeliac Disease (ESsCD) guideline for coeliac disease and other gluten-related disorders.

    abstract::This guideline presents recommendations for the management of coeliac disease (CD) and other gluten-related disorders both in adults and children. There has been a substantial increase in the prevalence of CD over the last 50 years and many patients remain undiagnosed. Diagnostic testing, including serology and biopsy...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章,实务指引

    doi:10.1177/2050640619844125

    authors: Al-Toma A,Volta U,Auricchio R,Castillejo G,Sanders DS,Cellier C,Mulder CJ,Lundin KEA

    更新日期:2019-06-01 00:00:00

  • Underwater endoscopic colorectal polyp resection: Feasibility in everyday clinical practice.

    abstract:Background:Endoscopic mucosal resection is well-established for resecting flat or sessile benign colon polyps. The novel underwater endoscopic mucosal resection eschews submucosal injection prior to endoscopic mucosal resection. Reports about underwater endoscopic mucosal resection were limited to small series of singl...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640617733923

    authors: Cadoni S,Liggi M,Gallittu P,Mura D,Fuccio L,Koo M,Ishaq S

    更新日期:2018-04-01 00:00:00

  • A combined bile and urine proteomic test for cholangiocarcinoma diagnosis in patients with biliary strictures of unknown origin.

    abstract:BACKGROUND:Detection of cholangiocarcinoma (CC) remains a diagnostic challenge particularly in patients with primary sclerosing cholangitis (PSC). We recently established diagnostic peptide marker models in bile and urine to detect CC. Our aim was to combine both models to reach a higher diagnostic accuracy of CC diagn...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640616687836

    authors: Voigtländer T,Metzger J,Schönemeier B,Jäger M,Mischak H,Manns MP,Lankisch TO

    更新日期:2017-08-01 00:00:00

  • Standard versus Endocuff versus cap-assisted colonoscopy for adenoma detection: A randomised controlled clinical trial.

    abstract:BACKGROUND AND AIMS:Adenoma detection rate (ADR) in colon cancer screening is most important for cancer prophylaxis. This work is the first three-armed randomised controlled clinical trial aimed at comparing a head-to-head setting standard colonoscopy (SC) with Endocuff-assisted colonoscopy (EC) and cap-assisted colono...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640620982952

    authors: Floer M,Tschaikowski L,Schepke M,Kempinski R,Neubauer K,Poniewierka E,Kunsch S,Ameis D,Heinzow HS,Auer A,Schmidt HH,Ellenrieder V,Meister T

    更新日期:2020-12-21 00:00:00

  • Prevalence of gastro-oesophageal reflux disease with upper gastrointestinal symptoms without heartburn and regurgitation.

    abstract:BACKGROUND:Symptomatically 'silent' gastro-oesophageal reflux disease (GORD) may be underdiagnosed. OBJECTIVE:To determine the prevalence of untreated GORD without heartburn and/or regurgitation in primary care. METHODS:Patients were included if they had frequent upper gastrointestinal symptoms and had not taken a pr...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640614532458

    authors: Vakil N,Wernersson B,Ohlsson L,Dent J

    更新日期:2014-06-01 00:00:00

  • Cytokine release after gluten ingestion differentiates coeliac disease from self-reported gluten sensitivity.

    abstract:BACKGROUND:Diagnosing coeliac disease (CD) in patients on a gluten-free diet (GFD) is difficult. Ingesting gluten elevates circulating interleukin (IL)-2, IL-8 and IL-10 in CD patients on a GFD. OBJECTIVE:We tested whether cytokine release after gluten ingestion differentiates patients with CD from those with self-rep...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640619874173

    authors: Tye-Din JA,Skodje GI,Sarna VK,Dzuris JL,Russell AK,Goel G,Wang S,Goldstein KE,Williams LJ,Sollid LM,Lundin KE,Anderson RP

    更新日期:2020-02-01 00:00:00

  • Underwater endoscopic mucosal resection: The third way for en bloc resection of colonic lesions?

    abstract:BACKGROUND:Underwater endoscopic mucosal resection without submucosal injection has been described for removing large flat colorectal lesions. OBJECTIVE:We aim to evaluate the reproducibility of this technique in terms of ease of implementation, safety and efficacy. METHODS:A prospective observational study of consec...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640615617635

    authors: Amato A,Radaelli F,Spinzi G

    更新日期:2016-08-01 00:00:00

  • Acute abdominal pain in the emergency department of a university hospital in Italy.

    abstract:BACKGROUND:Acute abdominal pain (AAP) is one of the most common causes of referral to an emergency department (ED), but information about its impact is limited. OBJECTIVES:The objectives of this article are to define the prevalence of AAP among ED visits in a large university hospital and analyze its main clinical fea...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640615606012

    authors: Caporale N,Morselli-Labate AM,Nardi E,Cogliandro R,Cavazza M,Stanghellini V

    更新日期:2016-04-01 00:00:00

  • Risk and outcomes of coronavirus disease (COVID-19) in patients with inflammatory bowel disease: a systematic review and meta-analysis.

    abstract:BACKGROUND:The risk of severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) infection and clinical outcomes of coronavirus disease (COVID-19) in inflammatory bowel disease are unclear. METHODS:We searched PubMed and Embase with the keywords: inflammatory bowel disease, Crohn's disease, ulcerative colit...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640620972602

    authors: Singh AK,Jena A,Kumar-M P,Sharma V,Sebastian S

    更新日期:2020-11-19 00:00:00

  • Clinical and endoscopic findings to assist the early detection of duodenal adenoma and adenocarcinoma.

    abstract:Background:Sporadic nonampullary duodenal adenocarcinoma is a rare malignant neoplasm in which poor prognosis is often associated with delayed diagnosis. Objective:A case-control study was designed to evaluate the clinical and endoscopic characteristics of patients with nonampullary duodenal epithelial tumours (NADETs...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640618817689

    authors: Matsuzaki J,Suzuki H,Shimoda M,Mori H,Fukuhara S,Miyoshi S,Masaoka T,Iwao Y,Kanai Y,Kanai T

    更新日期:2019-03-01 00:00:00

  • Rising incidence of acute pancreatitis in Sweden: National estimates and trends between 1990 and 2013.

    abstract:BACKGROUND:Recent reports from western countries have indicated an increased incidence and a decreased mortality in acute pancreatitis. However, the incidence assessment has often been hampered by the inclusion of both first-time and recurrent episodes of acute pancreatitis. METHODS:In this retrospective cohort study,...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640620913737

    authors: Oskarsson V,Hosseini S,Discacciati A,Videhult P,Jans A,Ekbom A,Sadr-Azodi O

    更新日期:2020-05-01 00:00:00

  • Gray scale and contrast-enhanced ultrasound imaging of malignant liver tumors of vascular origin.

    abstract:OBJECTIVES:Malignant vascular tumors of the liver are rare. The aim of this study was to investigate the applicability of gray scale and contrast-enhanced ultrasonography in patients with epithelioid hemangioendothelioma (EHE) of the liver and hepatic angiosarcoma (HA) and to describe the clinical presentation. METHOD...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640614560604

    authors: Schweitzer N,Soudah B,Gebel M,Manns MP,Boozari B

    更新日期:2015-02-01 00:00:00

  • Systematic review and meta-analysis: Efficacy and safety of POEM for achalasia.

    abstract:BACKGROUND:Peroral endoscopic esophageal myotomy (POEM) represents a less invasive alternative, as compared with conventional laparoscopic Heller myotomy for treating achalasia patients. In the last years, a number of prospective and retrospective experiences with POEM use for achalasia have been published. METHODS:Re...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640615581732

    authors: Barbieri LA,Hassan C,Rosati R,Romario UF,Correale L,Repici A

    更新日期:2015-08-01 00:00:00

  • In vitro fertilization-induced pregnancies predispose to gastroesophageal reflux disease.

    abstract:BACKGROUND:Women conceiving following in vitro fertilization (IVF) likely have a variety of risk factors that predispose them to gastroesophageal reflux disease (GERD) in the future. OBJECTIVE:We aimed to investigate whether pregnancy through IVF may predispose to subsequent GERD compared with pregnancies without IVF....

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640615597836

    authors: Turan I,Kitapcioglu G,Tavmergen Goker E,Sahin G,Bor S,Ege Reflux Study Group.

    更新日期:2016-04-01 00:00:00

  • The learning curve for needle knife precut sphincterotomy revisited.

    abstract:Background:There is no consensus on what constitutes adequate training for needle knife precut sphincterotomy. Objective:The purpose of this study was to determine the number of procedures required before effective and safe precut sphincterotomy can be achieved. Methods:This retrospective study examined the cumulativ...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640617701808

    authors: Li JW,Ang TL,Kam JW,Kwek ABE,Teo EK

    更新日期:2017-12-01 00:00:00

  • Natural history, diagnosis and treatment approach to fibrostenosing Crohn's disease.

    abstract::Stricturing Crohn's disease (CD) is a significant clinical problem. The presence of a stricture may be suggested by clinical symptoms. Cross-sectional imaging using computed tomography or magnetic resonance enterography is essential in diagnosing strictures as it allows further characterization and evaluation for comp...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640620901960

    authors: El Ouali S,Click B,Holubar SD,Rieder F

    更新日期:2020-04-01 00:00:00

  • Fecal SCFAs and SCFA-producing bacteria in gut microbiome of human NAFLD as a putative link to systemic T-cell activation and advanced disease.

    abstract:Background:Intestinal microbiota and their metabolites (e.g. short-chain fatty acids (SCFAs)) may influence nonalcoholic fatty liver disease (NAFLD). Objective:The objective of this article is to analyze gut bacterial diversity together with fecal SCFA concentrations and immunophenotyping of peripheral blood in histol...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640618804444

    authors: Rau M,Rehman A,Dittrich M,Groen AK,Hermanns HM,Seyfried F,Beyersdorf N,Dandekar T,Rosenstiel P,Geier A

    更新日期:2018-12-01 00:00:00

  • Development of benchmark quality criteria for assessing whole-endoscopy Barrett's esophagus biopsy cases.

    abstract:Background:Dysplasia in Barrett's esophagus (BE) biopsies is associated with low observer agreement among general pathologists. Therefore, expert review is advised. We are developing a web-based, national expert review panel for histological review of BE biopsies. Objective:The aim of this study was to create benchmar...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640618764710

    authors: van der Wel MJ,Duits LC,Klaver E,Pouw RE,Seldenrijk CA,Offerhaus G,Visser M,Ten Kate F,Tijssen JG,Bergman J,Meijer SL

    更新日期:2018-07-01 00:00:00

  • The two sides of the coin: Similarities and differences in the pathomechanisms of fistulas and stricture formations in irritable bowel disease.

    abstract::Fistulas and fibrosis or strictures represent frequent complications in irritable bowel disease (IBD) patients. To date, treatment options for fistulas are limited and surgery is often required. Similarly, no preventive treatment for fibrosis and stricture formation has been established. Frequently, stricture formatio...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章,评审

    doi:10.1177/2050640616635957

    authors: Scharl M,Bruckner RS,Rogler G

    更新日期:2016-08-01 00:00:00

  • Training in endoscopic mucosal resection and endoscopic submucosal dissection: Face, content and expert validity of the live porcine model.

    abstract:Introduction:Endoscopic mucosal resection and endoscopic submucosal dissection are demanding procedures. This study aims to establish face, content and expert validity of the live porcine model in performing endoscopic mucosal resection, endoscopic submucosal dissection, complication management and to assess it as a tr...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640617742484

    authors: Küttner-Magalhães R,Dinis-Ribeiro M,Bruno MJ,Marcos-Pinto R,Rolanda C,Koch AD

    更新日期:2018-05-01 00:00:00

  • Lack of seasonal variation in the incidence of eosinophilic oesophagitis in adolescent and adult non-PPI-responsive oesophageal eosinophilia midwestern US populations.

    abstract:BACKGROUND:Eosinophilic oesophagitis (EoO) has been associated with allergic disorders as well as aeroallergens. The current literature has shown a possible association between seasonal variation, mainly in the spring, and the incidence of EoO. However, this data was based on small population studies that did not exclu...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640614525152

    authors: Frederickson NW,Bayman L,Valestin J,Redd M,Lee YJ,Soubra M,Schey R

    更新日期:2014-04-01 00:00:00

  • Colonic motility in ulcerative colitis.

    abstract:BACKGROUND:Inflammatory conditions affecting the gut may cause motility disturbances, and ulcerative colitis - one of the main disorders among the inflammatory bowel diseases - may display abnormal colonic motility. AIM:To review the abnormalities of the large bowel in ulcerative colitis, by considering the motility, ...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章,评审

    doi:10.1177/2050640614548096

    authors: Bassotti G,Antonelli E,Villanacci V,Baldoni M,Dore MP

    更新日期:2014-12-01 00:00:00

  • Italian consensus conference for colonic diverticulosis and diverticular disease.

    abstract::The statements produced by the Consensus Conference on Diverticular Disease promoted by GRIMAD (Gruppo Italiano Malattia Diverticolare, Italian Group on Diverticular Diseases) are reported. Topics such as epidemiology, risk factors, diagnosis, medical and surgical treatment of diverticular disease (DD) in patients wit...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640614547068

    authors: Cuomo R,Barbara G,Pace F,Annese V,Bassotti G,Binda GA,Casetti T,Colecchia A,Festi D,Fiocca R,Laghi A,Maconi G,Nascimbeni R,Scarpignato C,Villanacci V,Annibale B

    更新日期:2014-10-01 00:00:00

  • Ethanol sclerotherapy or polidocanol sclerotherapy for symptomatic hepatic cysts.

    abstract:Background:Over the past decades, multiple approaches to aspiration sclerotherapy of large symptomatic hepatic cysts have been investigated. However, comparative data are scarce. Objective:The objective of this article is to compare cyst reduction, symptomatic relief, and adverse events between ethanol sclerotherapy a...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640618764940

    authors: Wijnands TF,Schoenemeier B,Potthoff A,Gevers TJ,Groenewoud H,Gebel MJ,Rifai K,Manns MP,Drenth JP

    更新日期:2018-07-01 00:00:00

  • Capability of processed EEG parameters to monitor conscious sedation in endoscopy is similar to general anaesthesia.

    abstract:BACKGROUND:Reliable and safe sedation is a prerequisite for endoscopic interventions. The current standard is rather safe, yet, an objective device to measure sedation depth is missing. To date, anaesthesia monitors based on processed electroencephalogram (EEG) have not been utilised in conscious sedation. OBJECTIVE:T...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640620959153

    authors: Garbe J,Eisenmann S,Kantelhardt JW,Duenninghaus F,Michl P,Rosendahl J

    更新日期:2020-09-14 00:00:00

  • Endoscopic modalities for the diagnosis of Barrett's oesophagus.

    abstract::Barrett's oesophagus is a pre-malignant condition associated with the development of oesophageal adenocarcinoma. Currently white light endoscopy and biopsy is the mainstay diagnostic tool. Yet this approach is troubled by issues related to cumbersome biopsy sampling, biopsy sampling errors and cost. Therefore in order...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章,评审

    doi:10.1177/2050640615619281

    authors: Sharma N,Srivastava S,Kern F,Xian W,Ming T,McKeon F,Ho KY

    更新日期:2016-12-01 00:00:00

  • Deprescribing medications that may increase the risk of hepatic encephalopathy: A qualitative study of patients with cirrhosis and their doctors.

    abstract:BACKGROUND AND AIMS:Multiple medications are associated with an increased risk of incident hepatic encephalopathy. Despite this known risk, medications such as opioids, benzodiazepines, gabapentin/pregabalin, and/or proton pump inhibitors are increasingly prescribed to persons with cirrhosis. Deprescribing is a promisi...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640620975224

    authors: Williams S,Louissaint J,Nikirk S,Bajaj JS,Tapper EB

    更新日期:2020-11-23 00:00:00

  • Vitamin D deficiency predicts severe acute pancreatitis.

    abstract:Background:The ability to predict the severity of disease is important to reduce morbidity and mortality in patients with acute pancreatitis (AP). Vitamin D deficiency has been associated with severity in various diseases. Objective:This study was conducted to assess vitamin D as a predictor of disease severity in pat...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/2050640618811489

    authors: Huh JH,Kim JW,Lee KJ

    更新日期:2019-02-01 00:00:00

  • Future research demands of the United European Gastroenterology (UEG) and its member societies.

    abstract:Aims:The purpose of this study was to initiate and stimulate collaborative research efforts to support United European Gastroenterology Federation (UEG) member societies facilitating digestive health research in European on the one hand and, on the other hand, to increase EU-funded digestive health research by providin...

    journal_title:United European gastroenterology journal

    pub_type: 杂志文章

    doi:10.1177/0142064X19858164

    authors: Enck P,Meisner S,Figueiredo C,Mayerle J,Ricciardiello L,UEG Research Committee.

    更新日期:2019-07-01 00:00:00