Abstract:
:An amendment to this paper has been published and can be accessed via a link at the top of the paper.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Chu AHY,Aris IM,Ng S,Loy SL,Bernard JY,Tint MT,Yuan WL,Godfrey KM,Chan JKY,Shek LP,Chong YS,Tan KH,Ang SB,Tan HH,Chern BSM,Yap F,Lee YS,Lek N,Leow MK,Khoo CM,Chan SYdoi
10.1038/s41598-020-69653-0subject
Has Abstractpub_date
2020-07-24 00:00:00pages
12744issue
1issn
2045-2322pii
10.1038/s41598-020-69653-0journal_volume
10pub_type
已发布勘误abstract::Förster Resonance Energy Transfer (FRET) allows for the visualization of nanometer-scale distances and distance changes. This sensitivity is regularly achieved in single-molecule experiments in vitro but is still challenging in biological materials. Despite many efforts, quantitative FRET in living samples is either r...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-62924-w
更新日期:2020-04-16 00:00:00
abstract::We present the first complete, closed genome sequences of Streptococcus pyogenes strains NCTC 8198T and CCUG 4207T, the type strain of the type species of the genus Streptococcus and an important human pathogen that causes a wide range of infectious diseases. S. pyogenes NCTC 8198T and CCUG 4207T are derived from depo...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-68249-y
更新日期:2020-07-15 00:00:00
abstract::Successful establishment of invasive species is often related to the existence of vacant niches. Competition occurs when invaders use the same limiting resources as members of the recipient community, which will be reflected in some overlap of their trophic niches. The concept of isotopic niche has been used to study ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep09715
更新日期:2015-05-19 00:00:00
abstract::The fungus-growing ant-microbe symbiosis is an ideal system to study chemistry-based microbial interactions due to the wealth of microbial interactions described, and the lack of information on the molecules involved therein. In this study, we employed a combination of MALDI imaging mass spectrometry (MALDI-IMS) and M...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-05515-6
更新日期:2017-07-17 00:00:00
abstract::Protein corona significantly affects in vivo fate of nanoparticles including biodistribution and half-life. Without manipulating the physicochemical properties of nanoparticles with considering their biointerference, attaining effective treatment protocols is impossible. For this reason, protein corona evolution and b...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-66572-y
更新日期:2020-06-15 00:00:00
abstract::The influence of catechol-o-methyltransferase (COMT) Val(158)Met on brain activation and functional connectivity has been widely reported. However, voxel-wise effects of this genotype on resting-state brain networks remain unclear. Here, we used resting-state fMRI and eigenvector centrality to examine the effects of C...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep10105
更新日期:2015-06-09 00:00:00
abstract::Insulin gene mutations have been identified to cause monogenic diabetes, and most of which developed permanent neonatal diabetes at young ages before 6 months of age in humans. To establish an animal model of permanent diabetes, we performed genome editing using the CRISPR/Cas9 system. We generated a novel Kuma mutant...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-68987-z
更新日期:2020-07-22 00:00:00
abstract::The aim of this study was to estimate the incidence of T2DM in three population groups: rural, rural-to-urban migrants and urban dwellers. Data from the PERU MIGRANT Study was analysed. The baseline assessment was conducted in 2007-2008 using a single-stage random sample and further follow-up was undertaken in 2015-16...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-23812-6
更新日期:2018-04-03 00:00:00
abstract::The influence of the growth conditions of multilayer CdTe/ZnTe quantum dots (QDs) on Si substrate upon their carrier dynamics is studied using intensity integration and broadening photoluminescence. The unusual temperature dependence of the line broadening is explained using a model for interband transitions that invo...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep08267
更新日期:2015-02-05 00:00:00
abstract::Interferon (IFN)-γ release assays (IGRAs) are used to diagnose latent tuberculosis (TB) infection (LTBI). To improve the accuracy of these tests, different approaches, such as alternative cytokine detection and using different antigens, are considered. Following this purpose, this study aims to evaluate the addition o...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-70204-w
更新日期:2020-08-06 00:00:00
abstract::Novelty seeking (NS) is a personality trait reflecting excitement in response to novel stimuli. High NS is usually a predictor of risky behaviour such as drug abuse. However, the relationships between NS and risk-related cognitive processes, including individual risk preference and the brain activation associated with...
journal_title:Scientific reports
pub_type: 临床试验,杂志文章
doi:10.1038/srep10534
更新日期:2015-06-11 00:00:00
abstract::Second-harmonic generation (SHG) is the most specific label-free indicator of collagen accumulation in widespread pathologies such as fibrosis, and SHG-based measurements hold important potential for biomedical analyses. However, efficient collagen SHG scoring in histological slides is hampered by the limited depth-of...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep29863
更新日期:2016-07-20 00:00:00
abstract::Information spreading in complex networks is often modeled as diffusing information with certain probability from nodes that possess it to their neighbors that do not. Information cascades are triggered when the activation of a set of initial nodes - seeds - results in diffusion to large number of nodes. Here, several...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-00937-8
更新日期:2017-04-18 00:00:00
abstract::Curcumin is an important bioactive component of turmeric and also one of the important natural products, which has been investigated extensively. The precise mode of action of curcumin and its impact on system level protein networks are still not well studied. To identify the curcumin governed regulatory action on pro...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-69011-0
更新日期:2020-07-21 00:00:00
abstract::Relativistic electron rings hold the possibility of very high accelerating rates, and hopefully a relatively cheap and compact accelerator/collimator for ultrahigh energy proton source. In this work, we investigate the generation of helical shaped quasi-monoenergetic relativistic electron beam and high-energy proton b...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-20506-x
更新日期:2018-02-01 00:00:00
abstract::The helicase Twinkle is indispensable for mtDNA replication in nucleoids. Previously, we showed that Twinkle is tightly membrane-associated even in the absence of mtDNA, which suggests that Twinkle is part of a membrane-attached replication platform. Here we show that this platform is a cholesterol-rich membrane struc...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep15292
更新日期:2015-10-19 00:00:00
abstract::The public goods game is a famous example illustrating the tragedy of the commons (Hardin in Science 162:1243-1248, 1968). In this game cooperating individuals contribute to a pool, which in turn is distributed to all members of the group, including defectors who reap the same rewards as cooperators without having mad...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-79731-y
更新日期:2020-12-28 00:00:00
abstract::Controlling the angular momentum of spins with very short external perturbations is a key issue in modern magnetism. For example it allows manipulating the magnetization for recording purposes or for inducing high frequency spin torque oscillations. Towards that purpose it is essential to modify and control the angula...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep08511
更新日期:2015-02-17 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-020-75277-1
更新日期:2020-10-20 00:00:00
abstract::Although lizards are often described as having robust neurogenic abilities, only a handful of the more than 6300 species have been explored. Here, we provide the first evidence of homeostatic neurogenesis in the leopard gecko (Eublepharis macularius). We focused our study on the medial cortex, homologue of the mammali...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-27880-6
更新日期:2018-06-25 00:00:00
abstract::We developed a solvothermal-induced self-assembly approach to construct three dimensional (3D) macroscopic Fe2O3 nanocubes/nitrogen-doped graphene (Fe2O3-NC/GN) aerogel as anode materials for lithium-ion batteries (LIBs). The Fe2O3 nanocubes with length of ~50 nm are homogeneously anchored on 3D GN frameworks and as s...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep07171
更新日期:2014-11-25 00:00:00
abstract::Inhalation exposure to airborne respirable crystalline silica (RCS) poses major health risks in many industrial environments. There is a need for new sensitive instruments and methods for in-field or near real-time measurement of crystalline silica aerosol. The objective of this study was to develop an approach, using...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-14363-3
更新日期:2017-10-24 00:00:00
abstract::Amplification of liver injury is mediated by macrophages but the signaling by which the macrophage inflammasome enhances liver injury is not completely understood. The CCAAT/Enhancer Binding Protein-β (C/EBPβ) is a critical signaling molecule for macrophages because expression of a dominant inhibitor of C/EBPβ DNA-bin...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep24268
更新日期:2016-04-12 00:00:00
abstract::The overall light energy to biomass conversion efficiency of plant photosynthesis is generally regarded as low. Forward genetic screens in Arabidopsis have yielded very few mutants with substantially enhanced photochemistry. Here, we report the isolation of a novel Arabidopsis mutant with a high operating efficiency o...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-03611-1
更新日期:2017-06-12 00:00:00
abstract::The dispersal of animals from their birth place has profound effects on the immediate survival and longer-term persistence of populations. Molecular studies have estimated that bumblebee colonies can be established many kilometers from their queens' natal nest site. However, little is known about when and how queens d...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-40355-6
更新日期:2019-03-20 00:00:00
abstract::MDN1/Rea1, as an AAA-type ATPase, is predicted to be the largest protein involved in pre-ribosome maturation in most organisms. However, its function in plant growth and development is poorly understood. Here, we characterized a novel Arabidopsis mutant, dwarf &short root (dsr) 1, which shows pleiotropic developmental...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep36446
更新日期:2016-11-08 00:00:00
abstract::Decreasing egg quality following oocyte ageing is a major restricting factor for the breeding programs. The mechanisms behind this process has not yet been clarified. To examine the possible involvement of oxidative stress in the oocyte ageing process, the relative mRNA abundance of specific transcripts were determine...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-46895-1
更新日期:2019-07-18 00:00:00
abstract::AS1411 is a G-rich DNA oligonucleotide that functions as an aptamer of the protein nucleolin, found at high levels on the surface of cancer cells but not on the surface of normal cells. Herein, we have studied AS1411 as a supramolecular carrier for the delivery of an acridine-based G-quadruplex ligand, C8, to HeLa can...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-44388-9
更新日期:2019-05-28 00:00:00
abstract::Coronary plaque distribution, frequency and cut-off value of percent stenosis for developing vasospasm are uncertain in patients with vasospastic angina (VA). We enrolled 2960 patients who received coronary angiography (CAG) and ergonovine provocation test prospectively in 11 university hospitals in Korea. A total of ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-62670-z
更新日期:2020-03-31 00:00:00
abstract::Exosomes are nano-sized endosome-derived small intraluminal vesicles, which are important facilitators of intercellular communication by transporting contents, such as protein, mRNA, and microRNAs, between neighboring cells, such as in the tumor microenvironment. The purpose of this study was to understand the mechani...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep30110
更新日期:2016-07-22 00:00:00