Topological and system-level protein interaction network (PIN) analyses to deduce molecular mechanism of curcumin.

abstract：:Delivery of proteins has been regarded as the safest and most useful application in therapeutic application of stem cells, because proteins can regulate gene expression transiently without any genomic alteration. However, it is difficult to accurately measure efficiency or quantity of intracellular protein uptake. Her...

journal_title：Scientific reports

authors： Jo J,Hong S,Choi WY,Lee DR

更新日期：2014-03-14 00:00:00

abstract：:As critical primary producers and recyclers of organic matter, the diversity of marine protists has been extensively explored by high-throughput barcode sequencing. However, classification of short metabarcoding sequences into traditional taxonomic units is not trivial, especially for lineages mainly known by their ge...

journal_title：Scientific reports

authors： Cai R,Kayal E,Alves-de-Souza C,Bigeard E,Corre E,Jeanthon C,Marie D,Porcel BM,Siano R,Szymczak J,Wolf M,Guillou L

更新日期：2020-02-13 00:00:00

abstract：:Climatic changes can induce geographic expansion and altitudinal shifts in the distribution of invasive species by offering more thermally suitable habitats. At the remote sub-Antarctic Kerguelen Islands, the predatory insect Merizodus soledadinus (Coleoptera: Carabidae), introduced in 1913, rapidly invaded coastal ha...

journal_title：Scientific reports

authors： Ouisse T,Day E,Laville L,Hendrickx F,Convey P,Renault D

更新日期：2020-01-27 00:00:00

abstract：:The LiBH4/CaH2 composite are firstly studied as Concentrating Solar Power Thermal Storage Material. The LiBH4/CaH2 composite according to the stoichiometric ratio are synthesized by high-energy ball milling method. The kinetics, thermodynamics and cycling stability of LiBH4/CaH2 composite are investigated by XRD (X-ra...

journal_title：Scientific reports

authors： Li Y,Li P,Qu X

更新日期：2017-01-31 00:00:00

abstract：:MicroRNAs (miRNAs) are important effectors in mediating host-pathogen interaction. In this report, coelomocytes miRNA libraries of three Japanese sea cucumbers Apostichopus japonicus were built by Illumina(®) Hiseq2000 from different time points after lipopolysaccharide challenge (at time 0 h, 6 h and 12 h). The clean...

journal_title：Scientific reports

authors： Zhong L,Zhang F,Zhai Y,Cao Y,Zhang S,Chang Y

更新日期：2015-12-04 00:00:00

abstract：:The development of well-organized structures with high luminescent properties in the solid and aggregated states is of both scientific and technological interest due to their applications in nanotechnology. In this paper we described the synthesis of amphiphilic and dumbbell shaped AIE-active tetraphenylethylene (TPE)...

journal_title：Scientific reports

authors： Salimimarand M,La DD,Kobaisi MA,Bhosale SV

更新日期：2017-02-23 00:00:00

abstract：:The CRISPR/Cas9 system is a powerful method of editing genes by randomly introducing errors into the target sites. Here, we describe a CRISPR-based test for gene essentiality (CRISPR-E test) that allows the identification of essential genes. Specifically, we use sgRNA-mediated CRISPR/Cas9 to target the open reading fr...

journal_title：Scientific reports

authors： You Y,Ramachandra SG,Jin T

更新日期：2020-09-08 00:00:00

abstract：:Visible indication based on the aggregation of colloidal nanoparticles (NPs) is highly advantageous for rapid on-site detection of biological entities, which even untrained persons can perform without specialized instrumentation. However, since the extent of aggregation should exceed a certain minimum threshold to pro...

journal_title：Scientific reports

authors： Lim S,Koo OK,You YS,Lee YE,Kim MS,Chang PS,Kang DH,Yu JH,Choi YJ,Gunasekaran S

更新日期：2012-01-01 00:00:00

abstract：:Little-Parks effect names the oscillations in the superconducting critical temperature as a function of the magnetic field. This effect is related to the geometry of the sample. In this work, we show that this effect can be enhanced and manipulated by the inclusion of magnetic nanostructures with perpendicular magneti...

journal_title：Scientific reports

authors： de Ory MC,Rollano V,Gomez A,Menghini M,Muñoz-Noval A,Gonzalez EM,Vicent JL

更新日期：2020-06-25 00:00:00

abstract：:Myelination is critical for transduction of neuronal signals, neuron survival and normal function of the nervous system. Myelin disorders account for many debilitating neurological diseases such as multiple sclerosis and leukodystrophies. The lack of experimental models and tools to observe and manipulate this process...

journal_title：Scientific reports

authors： Espinosa-Hoyos D,Jagielska A,Homan KA,Du H,Busbee T,Anderson DG,Fang NX,Lewis JA,Van Vliet KJ

更新日期：2018-01-11 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Wang Y,Chen D,He X,Shen J,Xiong M,Wang X,Zhou D,Wei Z

更新日期：2020-02-20 00:00:00

abstract：:A new compact silicon grating coupler enabling fibre-to-chip light coupling at a minimized taper length is proposed. The proposed coupler, which incorporates a hollow tapered waveguide, converts the spot-size of optical modes from micro- to nano-scales by reducing the lateral dimension from 15 µm to 300 nm at a length...

journal_title：Scientific reports

authors： Asaduzzaman M,Bakaul M,Skafidas E,Khandokar MRH

更新日期：2018-02-07 00:00:00

abstract：:The ammonia removal as well as the current efficiency during electrolysis was investigated by using a vermiculite-packed electrochemical reactor under continuous mode. Experimental results showed that adsorption of ammonia by vermiculite and electrolytic desorption of ammonia simultaneously existed in the reactor, lea...

journal_title：Scientific reports

authors： Li L,Yao J,Fang X,Huang Y,Mu Y

更新日期：2017-01-19 00:00:00

abstract：:Oxalate decarboxylase (OXDC) enzyme has immense biotechnological applications due to its ability to decompose anti-nutrient oxalic acid. Flammulina velutipes, an edible wood rotting fungus responds to oxalic acid by induction of OXDC to maintain steady levels of pH and oxalate anions outside the fungal hyphae. Here, w...

journal_title：Scientific reports

authors： Kamthan A,Kamthan M,Kumar A,Sharma P,Ansari S,Thakur SS,Chaudhuri A,Datta A

更新日期：2015-10-12 00:00:00

abstract：:We investigated the dynamics of the interaction between spin-polarized photo-created carriers and Mn ions on InGaAs/GaAs: Mn structures. The carriers are confined in an InGaAs quantum well and the Mn ions come from a Mn delta-layer grown at the GaAs barrier close to the well. Even though the carriers and the Mn ions a...

journal_title：Scientific reports

authors： Balanta MA,Brasil MJ,Iikawa F,Mendes UC,Brum JA,Danilov YA,Dorokhin MV,Vikhrova OV,Zvonkov BN

更新日期：2016-04-15 00:00:00

abstract：:Amyloid formation is associated with various pathophysiological conditions like Alzheimer's and Parkinson's diseases as well as many useful functions. The hallmark of amyloid assemblies is a conformational transition of the constituent proteins into a β - sheet rich filament. Accounting for this conformational transit...

journal_title：Scientific reports

authors： Ranganathan S,Ghosh D,Maji SK,Padinhateeri R

更新日期：2016-02-17 00:00:00

abstract：:Although increases in cardiovascular load (pressure overload) are known to elicit ventricular remodeling including cardiomyocyte hypertrophy and interstitial fibrosis, the molecular mechanisms of pressure overload or AngII -induced cardiac interstitial fibrosis remain elusive. In this study, serpinE2/protease nexin-1 ...

journal_title：Scientific reports

authors： Li X,Zhao D,Guo Z,Li T,Qili M,Xu B,Qian M,Liang H,E X,Chege Gitau S,Wang L,Huangfu L,Wu Q,Xu C,Shan H

更新日期：2016-11-23 00:00:00

abstract：:Bacterial proteins exported to the cell surface play key cellular functions. However, despite the interest to study the localisation of surface proteins such as adhesins, transporters or hydrolases, monitoring their dynamics in live imaging remains challenging, due to the limited availability of fluorescent probes rem...

journal_title：Scientific reports

authors： Chekli Y,Peron-Cane C,Dell'Arciprete D,Allemand JF,Li C,Ghigo JM,Gautier A,Lebreton A,Desprat N,Beloin C

更新日期：2020-09-25 00:00:00

abstract：:Stem cell therapy has long been considered a promising mode of treatment for many incurable diseases. Human mesenchymal stem cells (hMSCs) have provided the most promising results to date for regenerative medicine. Nevertheless, due to several obstacles such as difficulty in sourcing and characterizing hMSCs, they rem...

journal_title：Scientific reports

authors： Jeong GJ,Kang D,Kim AK,Han KH,Jeon HR,Kim DI

更新日期：2019-04-16 00:00:00

abstract：:Pulsatillae radix is a conventional traditional Chinese medicine (TCM) with common name Baitouweng, and has notable effects on inflammation and dysentery. Pulsatilla chinensis (Bge.) Regel is the only source plant of Baitouweng recorded in Chinese Pharmacopoeia, but its adulteration often occurs in the market that pos...

journal_title：Scientific reports

authors： Shi Y,Zhao M,Yao H,Yang P,Xin T,Li B,Sun W,Chen S

更新日期：2017-01-06 00:00:00

abstract：:In bacteria, selective promoter recognition by RNA polymerase is achieved by its association with σ factors, accessory subunits able to direct RNA polymerase "core enzyme" (E) to different promoter sequences. Using Chromatin Immunoprecipitation-sequencing (ChIP-seq), we searched for promoters bound by the σ(S)-associa...

journal_title：Scientific reports

authors： Peano C,Wolf J,Demol J,Rossi E,Petiti L,De Bellis G,Geiselmann J,Egli T,Lacour S,Landini P

更新日期：2015-05-28 00:00:00

abstract：:Orientation controllable DNA biosensors hold great application potentials in recognizing small molecules and detecting DNA hybridization. Though electric field is usually used to control the orientation of DNA molecules, it is also of great importance and significance to seek for other triggered methods to control the...

journal_title：Scientific reports

authors： Feng C,Ding HM,Ren CL,Ma YQ

更新日期：2015-09-24 00:00:00

abstract：:To evaluate the efficacy and safety of CyberKnife Stereotactic Body Radiation Therapy (SBRT) in the treatment of adrenal gland metastases (AGM), we designed a large-scale multicenter retrospective study to report the safety and efficacy of SBRT for inoperable AGM. In this study, 75 (61 males, 14 females) patients with...

journal_title：Scientific reports

authors： Zhao X,Zhu X,Zhuang H,Guo X,Song Y,Ju X,Wang P,Yuan Z,Zhang H

更新日期：2020-05-12 00:00:00

abstract：:The overlap between pain and reward processing pathways leds researchers to hypothesize that there are interactions between them in the human brain. Two hypotheses have been proposed. The "competition hypothesis" posits that reward can reduce pain-related neural activity and vice versa. The "salience hypothesis" sugge...

journal_title：Scientific reports

authors： Cui F,Zhu X,Gu R,Luo YJ

更新日期：2016-05-19 00:00:00

abstract：:In recent years, active targeting strategies by ligand modification have emerged to enhance tumor accumulation of NP, but their clinical application was strictly restricted due to the complex preparation procedures, poor stability and serious toxicity. An effective and clinical translational strategy is required to sa...

journal_title：Scientific reports

authors： Hu G,Cun X,Ruan S,Shi K,Wang Y,Kuang Q,Hu C,Xiao W,He Q,Gao H

更新日期：2016-06-08 00:00:00

abstract：:Damnacanthal, an anthraquinone present in noni plants, targets several tyrosine kinases and has antitumoral effects. This study aims at getting additional insight on the potential of damnacanthal as a natural antitumor compound. The direct effect of damnacanthal on c-Met was tested by in vitro activity assays. Additio...

journal_title：Scientific reports

authors： García-Vilas JA,Quesada AR,Medina MA

更新日期：2015-01-26 00:00:00

abstract：:Reliable quantification of miRNA expression by qRT-PCR crucially depends on validated housekeepers for data normalization. Here we present thoroughly tested miRNAs eligible as references in immunological studies utilizing endothelial cells and macrophages, respectively. Endothelial cells (cell line: TIME) and macropha...

journal_title：Scientific reports

authors： Link F,Krohn K,Schumann J

更新日期：2019-09-04 00:00:00

abstract：:Lactic acidosis is common in critical care; by contrast, a subtype called alcohol-associated lactic acidosis (AALA) is rarely encountered. The primary purpose of this study was to determine the prognosis of AALA in critically ill patients and the second aim was to determine whether the survival was associated to the p...

journal_title：Scientific reports

authors： Yang CC,Chan KS,Tseng KL,Weng SF

更新日期：2016-10-17 00:00:00

abstract：:Despite the increasing number of studies conducted recently to evaluate the association between HPV infections and the risk of prostate cancer, the results remain inconclusive. Furthermore, the prevalence and distribution of overall and individual HPV types worldwide in prostate cancer has not been reported until now....

journal_title：Scientific reports

authors： Yang L,Xie S,Feng X,Chen Y,Zheng T,Dai M,Zhou CK,Hu Z,Li N,Hang D

更新日期：2015-10-06 00:00:00

abstract：:Site conditions and forest management affect dendrometric parameters of chestnut (Castanea sativa Mill.) coppices, but there is modest knowledge on the effect of stand dendrometric characters on physical and mechanical wood characteristics. The aim of this study was to verify these relationships in chestnut coppices t...

journal_title：Scientific reports

authors： Marini F,Manetti MC,Corona P,Portoghesi L,Vinciguerra V,Tamantini S,Kuzminsky E,Zikeli F,Romagnoli M

更新日期：2021-01-15 00:00:00