Telomere Dynamics in the Diploid and Triploid Rainbow Trout (Oncorhynchus mykiss) Assessed by Q-FISH Analysis.

abstract：:In forensics, mitochondrial DNA (mtDNA) analysis is foremost applied to rootless hairs often lacking detectable nuclear DNA. Sanger sequencing is the routine mtDNA method in most forensic laboratories, even though interpretation of mixed samples and heteroplasmic sites can be challenging. Individuals may hold cells wi...

journal_title：Genes

authors： Gaag KJV,Desmyter S,Smit S,Prieto L,Sijen T

更新日期：2020-11-16 00:00:00

abstract：:Prader-Willi Syndrome Association (USA) monitors the ongoing health and welfare of individuals with Prader-Willi syndrome (PWS) through active communication with members by membership surveys and data registries. Thromboembolism and blood clots have emerged in clinical studies as significant risk factors for injury an...

journal_title：Genes

authors： Manzardo AM,Heinemann J,McManus B,Loker C,Loker J,Butler MG

更新日期：2019-07-19 00:00:00

abstract：:Amazonian puffing snakes (Spilotes; Colubridae) are snakes widely distributed in the Neotropical region. However, chromosomal data are scarce in this group and, when available, are only limited to karyotype description using conventional staining. In this paper, we focused on the process of karyotype evolution and tre...

journal_title：Genes

authors： Viana PF,Ezaz T,de Bello Cioffi M,Jackson Almeida B,Feldberg E

更新日期：2019-04-09 00:00:00

abstract：:Mobile DNA elements play a significant evolutionary role by promoting genome plasticity. Insertion sequences are the smallest prokaryotic transposable elements. They are highly diverse elements, and the ability to accurately identify, annotate, and infer the full genomic impact of insertion sequences is lacking. Halan...

journal_title：Genes

authors： Sadler M,R Mormile M,L Frank R

更新日期：2020-04-29 00:00:00

abstract：:The northern sea otter inhabits coastal waters of the northern Pacific Ocean and is the largest member of the Mustelidae family. DNA sequencing methods that utilize microfluidic partitioned and non-partitioned library construction were used to establish the sea otter genome. The final assembly provided 2.426 Gbp of hi...

journal_title：Genes

authors： Jones SJ,Haulena M,Taylor GA,Chan S,Bilobram S,Warren RL,Hammond SA,Mungall KL,Choo C,Kirk H,Pandoh P,Ally A,Dhalla N,Tam AKY,Troussard A,Paulino D,Coope RJN,Mungall AJ,Moore R,Zhao Y,Birol I,Ma Y,Marra M,Jo

更新日期：2017-12-11 00:00:00

abstract：:Golgi reassembly and stacking protein (GRASP) is required for polysaccharide secretion and virulence in Cryptococcus neoformans. In fungal species, extracellular vesicles (EVs) participate in the export of polysaccharides, proteins and RNA. In the present work, we investigated if EV-mediated RNA export is functionally...

journal_title：Genes

authors： Peres da Silva R,Martins ST,Rizzo J,Dos Reis FCG,Joffe LS,Vainstein M,Kmetzsch L,Oliveira DL,Puccia R,Goldenberg S,Rodrigues ML,Alves LR

更新日期：2018-08-08 00:00:00

abstract：:Gruiformes is a group with phylogenetic issues. Recent studies based on mitochondrial and genomic DNA have proposed the existence of a core Gruiformes, consisting of five families: Heliornithidae, Aramidae, Gruidae, Psophiidae and Rallidae. Karyotype studies on these species are still scarce, either by conventional st...

journal_title：Genes

authors： Furo IO,Kretschmer R,O'Brien PCM,Pereira JC,Ferguson-Smith MA,de Oliveira EHC

更新日期：2020-03-13 00:00:00

abstract：:Death investigations often include an effort to establish the postmortem interval (PMI) in cases in which the time of death is uncertain. The postmortem interval can lead to the identification of the deceased and the validation of witness statements and suspect alibis. Recent research has demonstrated that microbes pr...

journal_title：Genes

authors： Belk A,Xu ZZ,Carter DO,Lynne A,Bucheli S,Knight R,Metcalf JL

更新日期：2018-02-16 00:00:00

abstract：:The sea lamprey (Petromyzon marinus) is one of few vertebrate species known to reproducibly eliminate large fractions of its genome during normal embryonic development. This germline-specific DNA is lost in the form of large fragments, including entire chromosomes, and available evidence suggests that DNA elimination ...

journal_title：Genes

authors： Timoshevskiy VA,Timoshevskaya NY,Smith JJ

更新日期：2019-10-22 00:00:00

abstract：BACKGROUND:Large-scale screening of drug sensitivity on cancer cell models can mimic in vivo cellular behavior providing wider scope for biological research on cancer. Since the therapeutic effect of a single drug or drug combination depends on the individual patient's genome characteristics and cancer cells integratio...

journal_title：Genes

authors： Cheng L,Majumdar A,Stover D,Wu S,Lu Y,Li L

更新日期：2020-02-28 00:00:00

abstract：:Heat stress (HS) is challenging in humans and animals as it is a complicated regulatory mechanism. This prompted us to characterize the physiological and molecular responses of a HS-animal model. In this study, a rat model system was developed by using three temperature treatments (40 ℃, 42 ℃, and 43 ℃) and sixteen bi...

journal_title：Genes

authors： Dou J,Khan A,Khan MZ,Mi S,Wang Y,Yu Y,Wang Y

更新日期：2020-03-13 00:00:00

abstract：:Feed cost accounts for approximately 65-75% of overall commercial pork production costs. Therefore, improving the feed efficiency of pig production is important. In this study, 12 individuals with either extremely high (HE) or low (LE) feed efficiency were selected from 225 Duroc × (Landrace × Yorkshire) (DLY) pigs. A...

journal_title：Genes

authors： Wang X,Li S,Wu J,Ding R,Quan J,Zheng E,Yang J,Wu Z

更新日期：2019-09-18 00:00:00

abstract：:Mitochondrial dynamics are known to have an important role in so-called age-related diseases, including cancer. Mitochondria is an organelle involved in many key cellular functions and responds to physiologic or stress stimuli by adapting its structure and function. Perhaps the most important structural changes involv...

journal_title：Genes

authors： Lima AR,Santos L,Correia M,Soares P,Sobrinho-Simões M,Melo M,Máximo V

更新日期：2018-02-21 00:00:00

abstract：:The Sichuan partridge (Arborophila rufipectus, Phasianidae, Galliformes) is distributed in south-west China, and classified as endangered grade. To examine the evolution and genomic features of Sichuan partridge, we de novo assembled the Sichuan partridge reference genome. The final draft assembly consisted of approxi...

journal_title：Genes

authors： Zhou C,Tu H,Yu H,Zheng S,Dai B,Price M,Wu Y,Yang N,Yue B,Meng Y

更新日期：2019-09-05 00:00:00

abstract：:The transcription factor PAX6 is essential in ocular development in vertebrates, being considered the master regulator of the eye. During eye development, it is essential for the correct patterning and formation of the multi-layered optic cup and it is involved in the developing lens and corneal epithelium. In adultho...

journal_title：Genes

authors： Lima Cunha D,Arno G,Corton M,Moosajee M

更新日期：2019-12-17 00:00:00

abstract：:The large phenotypic variation in the olfactory bulb may be related to heterogeneity in the progenitor cells. Accordingly, the progeny of subventricular zone (SVZ) progenitor cells that are destined for the olfactory bulb is of particular interest, specifically as there are many facets of these progenitors and their m...

journal_title：Genes

authors： Sánchez-González R,Figueres-Oñate M,Ojalvo-Sanz AC,López-Mascaraque L

更新日期：2020-03-13 00:00:00

abstract：:Xyloglucan endotransglycosylase/hydrolase (XTH) is a cell-wall-modifying enzyme participating in diverse cell morphogenetic processes and adaptation to stress. In this study, 48 XTH genes were identified from two pineapple (Ananas comosus) cultivars ('F153' and 'MD2') and designated Ac(F153)XTH1 to -24 and Ac(MD2)XTH1...

journal_title：Genes

authors： Li Q,Li H,Yin C,Wang X,Jiang Q,Zhang R,Ge F,Chen Y,Yang L

更新日期：2019-07-16 00:00:00

abstract：:Oral vaccination is a practical method for the active immunization of farmed fish in the matter of animal welfare and handling costs. However, it always shows insufficient protective immunity, mainly due to antigen degradation in the gastrointestinal tract (GIT). Bacillus subtilis spores have been shown to be able to ...

journal_title：Genes

authors： Sun R,Zhang M,Chen H,Wei Y,Ning D

更新日期：2020-11-14 00:00:00

abstract：:Balanced chromosome rearrangements are one of the main etiological factors contributing to hypoprolificacy in the domestic pig. Amongst domestic animals, the pig is considered to have the highest prevalence of chromosome rearrangements. To date over 200 unique chromosome rearrangements have been identified. The factor...

journal_title：Genes

authors： Donaldson B,Villagomez DAF,Revay T,Rezaei S,King WA

更新日期：2019-09-30 00:00:00

abstract：:We report the underlying genetic causes of prelingual hearing loss (HL) segregating in eight large consanguineous families, ascertained from the Punjab province of Pakistan. Exome sequencing followed by segregation analysis revealed seven potentially pathogenic variants, including four novel alleles c.257G>A, c.6083A>...

journal_title：Genes

authors： Zafar S,Shahzad M,Ishaq R,Yousaf A,Shaikh RS,Akram J,Ahmed ZM,Riazuddin S

更新日期：2020-08-22 00:00:00

abstract：:Photoperiod is one of the important factors leading to seasonal reproduction of sheep. However, the molecular mechanisms underlying the photoperiod regulation of seasonal reproduction remain poorly understood. In this study, we compared the expression profiles of mRNAs, lncRNAs, and circRNAs in uterine tissues from Su...

journal_title：Genes

authors： La Y,He X,Zhang L,Di R,Wang X,Gan S,Zhang X,Zhang J,Hu W,Chu M

更新日期：2020-03-12 00:00:00

abstract：:Aminoacyl-tRNA synthetases (aaRSs) are key enzymes in the mRNA translation machinery, yet they possess numerous non-canonical functions developed during the evolution of complex organisms. The aaRSs and aaRS-interacting multi-functional proteins (AIMPs) are continually being implicated in tumorigenesis, but these conn...

journal_title：Genes

authors： Wang J,Vallee I,Dutta A,Wang Y,Mo Z,Liu Z,Cui H,Su AI,Yang XL

更新日期：2020-11-22 00:00:00

abstract：:Bupleurum falcatum, which belongs to the family Apiaceae, has long been applied for curative treatments, especially as a liver tonic, in herbal medicine. The chloroplast (cp) genome has been an ideal model to perform the evolutionary and comparative studies because of its highly conserved features and simple structure...

journal_title：Genes

authors： Shin DH,Lee JH,Kang SH,Ahn BO,Kim CK

更新日期：2016-05-13 00:00:00

abstract：:We set out to assess the NIH/3T3 cell proliferation activity of Arabidopsis oil body-expressed recombinant oleosin-hEGF-hEGF protein. Normally, human epidermal growth factor (hEGF) is purified through complex process, however, oleosin fusion technology provides an inexpensive and scalable platform for its purification...

journal_title：Genes

authors： Qiang W,Gao T,Lan X,Guo J,Noman M,Li Y,Guo Y,Kong J,Li H,Du L,Yang J

更新日期：2020-08-19 00:00:00

abstract：:The homeodomain-leucine zipper (HD-Zip) transcription factor family is a key transcription factor family and unique to the plant kingdom. It consists of a homeodomain and a leucine zipper that serve in combination as a dimerization motif. The family can be classified into four subfamilies, and these subfamilies partic...

journal_title：Genes

authors： Song A,Li P,Xin J,Chen S,Zhao K,Wu D,Fan Q,Gao T,Chen F,Guan Z

更新日期：2016-05-17 00:00:00

abstract：:The P-type plasma membrane (PM) H+-ATPase plays a major role during the growth and development of a plant. It is also involved in plant resistance to a variety of biotic and abiotic factors, including salt stress. The PM H+-ATPase gene family has been well characterized in Arabidopsis and other crop plants such as ric...

journal_title：Genes

authors： Xu Z,Marowa P,Liu H,Du H,Zhang C,Li Y

更新日期：2020-03-27 00:00:00

abstract：:One of the primary objectives of plant biotechnology is to increase resistance to abiotic stresses, such as salinity. Salinity is a major abiotic stress and increasing crop resistant to salt continues to the present day as a major challenge. Salt stress disturbs cellular environment leading to protein misfolding, affe...

journal_title：Genes

authors： Villarino GH,Hu Q,Scanlon MJ,Mueller L,Bombarely A,Mattson NS

更新日期：2017-08-03 00:00:00

abstract：:Marek's Disease is a lymphoproliferative disease of chickens caused by Marek's Disease Virus. Similar to other herpesviruses, Marek's Disease Virus (MDV) encodes its own small non-coding regulatory RNAs termed microRNAs (miRNAs). We previously found that the expression profile of these viral miRNAs is affected by vacc...

journal_title：Genes

authors： Hicks JA,Liu HC

更新日期：2019-02-05 00:00:00

abstract：:Induced point mutations are important genetic resources for their ability to create hypo- and hypermorphic alleles that are useful for understanding gene functions and breeding. However, such mutant populations have only been developed for a few temperate maize varieties, mainly B73 and W22, yet no tropical maize inbr...

journal_title：Genes

authors： Tran QH,Bui NH,Kappel C,Dau NTN,Nguyen LT,Tran TT,Khanh TD,Trung KH,Lenhard M,Vi SL

更新日期：2020-03-06 00:00:00

abstract：:In this contribution, the aspects of reptile and amphibian speciation that emerged from research performed over the past decade are reviewed. First, this study assesses how patterns and processes of speciation depend on knowing the taxonomy of the group in question, and discuss how integrative taxonomy has contributed...

journal_title：Genes

authors： Wollenberg Valero KC,Marshall JC,Bastiaans E,Caccone A,Camargo A,Morando M,Niemiller ML,Pabijan M,Russello MA,Sinervo B,Werneck FP,Sites JW,Jr.,Wiens JJ,Steinfartz S

更新日期：2019-08-26 00:00:00