Abstract:
:Aluminium alloys are re-evaluated as most feasible way to satisfy the industrial needs of light-weight structural materials. However, unlike conventional structural metals such as iron and titanium, aluminium does not have easily accessible secondary phases, which means that aluminium-based alloys cannot be strengthened by harnessing multiple phases. This leaves age hardening as the only feasible strengthening approach. Highly concentrated precipitates generated by age hardening generally play a dominant role in shaping the mechanical properties of aluminium alloys. In such precipitates, it is commonly believed that the coherent interface between the matrix and precipitate does not contribute to crack initiation and embrittlement. Here, we show that this is not the case. We report an unexpected spontaneous fracture process associated with hydrogen embrittlement. The origin of this quasi-cleavage fracture involves hydrogen partitioning, which we comprehensively investigate through experiment, theory and first-principles calculations. Despite completely coherent interface, we show that the aluminium-precipitate interface is a more preferable trap site than void, dislocation and grain boundary. The cohesivity of the interface deteriorates significantly with increasing occupancy, while hydrogen atoms are stably trapped up to an extremely high occupancy over the possible trap site. Our insights indicate that controlling the hydrogen distribution plays a key role to design further high-strength and high-toughness aluminium alloys.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Tsuru T,Shimizu K,Yamaguchi M,Itakura M,Ebihara K,Bendo A,Matsuda K,Toda Hdoi
10.1038/s41598-020-58834-6subject
Has Abstractpub_date
2020-04-06 00:00:00pages
1998issue
1issn
2045-2322pii
10.1038/s41598-020-58834-6journal_volume
10pub_type
杂志文章abstract::Phagocytosis is a process in which target cells or particles are engulfed and taken up by other cells, typically professional phagocytes; this process is crucial in many physiological processes and disease states. The detection of targets for phagocytosis is directed by a complex repertoire of cell surface receptors. ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-38127-9
更新日期:2019-02-13 00:00:00
abstract::No consensus currently exist on the optimal treatment of patients with high-risk nonmuscle invasive (HGT1) micropapillary variant of bladder cancer (MPBC). Transcripsome analysis may allow stratification of MPBC-HGT1 enabling prediction of recurrence and guide therapeutic management for individual patients. Whole tran...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-76904-7
更新日期:2020-11-18 00:00:00
abstract::The aim of this study was to evaluate the impact of lymph node status from neck dissection pathological specimens on the survival for isolated regional nodal recurrence or persistence after primary treatment of nasopharyngeal carcinoma. Through a retrospective cohort study performed in an academic tertiary referral ho...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-62625-4
更新日期:2020-03-27 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-020-67129-9
更新日期:2020-06-17 00:00:00
abstract::Highly invasive animal based test procedures for risk assessment such as the Draize eye test are under increasing criticism due to poor transferability for the human organism and animal-welfare concerns. However, besides all efforts, the Draize eye test is still not completely replaced by alternative animal-free metho...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-33118-2
更新日期:2018-10-09 00:00:00
abstract::Enterococci are nosocomial pathogens that can form biofilms, which contribute to their virulence and antibiotic resistance. Although many genes involved in biofilm formation have been defined, their distribution among enterococci has not been comprehensively studied on a genome scale, and their diagnostic ability to p...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-05901-0
更新日期:2017-07-18 00:00:00
abstract::Hand size perceptual distortions characterize adult human cognition. Notwithstanding the importance of uncovering how hand size representation develops in humans, studies in this field are still at a preliminary stage. Indeed, it is yet to be understood whether hand size distortions are present and reliable in early c...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-62206-5
更新日期:2020-03-25 00:00:00
abstract::We have recently reported that Kupffer cells consist of two subsets, radio-resistant resident CD68+ Kupffer cells and radio-sensitive recruited CD11b+ Kupffer cells/macrophages (Mφs). Non-alcoholic steatohepatitis (NASH) is characterized not only by hepatic steatosis but also chronic inflammation and fibrosis. In the ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep34466
更新日期:2016-10-06 00:00:00
abstract::We investigated the clinical characteristics of cilioretinal arteries (CAs) and cilioretinal veins (CVs) in eyes with pathologic myopia. Ninety-five eyes with pathologic myopia and CAs were studied. The retrobulbar vessels from which the CAs originated were identified by indocyanine green angiography (ICGA). The resul...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-38616-5
更新日期:2019-02-21 00:00:00
abstract::Ovarian cancer (OC) is the most lethal gynecological carcinoma due to the lack of diagnostic markers and effective drug targets. Discovery of new therapeutic targets in OC to improve the treatment outcome is urgently needed. We performed proteomic analysis of OC specimens and the paired normal tissues and revealed tha...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-48992-7
更新日期:2019-09-02 00:00:00
abstract::Heat stress threatens agriculture worldwide. Plants acquire heat stress tolerance through priming, which establishes stress memory during mild or severe transient heat stress. Such induced thermotolerance restructures metabolic networks and helps maintain metabolic homeostasis under heat stress. Here, we used an elect...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-36484-z
更新日期:2019-01-17 00:00:00
abstract::Idiopathic pulmonary fibrosis (IPF) is a progressive disease characterized by interstitial remodeling and pulmonary dysfunction. The etiology of IPF is not completely understood but involves pathologic inflammation and subsequent failure to resolve fibrosis in response to epithelial injury. Treatments for IPF are limi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-68336-0
更新日期:2020-07-15 00:00:00
abstract::The black rhinoceros is again on the verge of extinction due to unsustainable poaching in its native range. Despite a wide historic distribution, the black rhinoceros was traditionally thought of as depauperate in genetic variation, and with very little known about its evolutionary history. This knowledge gap has hamp...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep41417
更新日期:2017-02-08 00:00:00
abstract::Mammalian sperm are unable to fertilize the egg immediately after ejaculation. To gain fertilization competence, they need to undergo a series of modifications inside the female reproductive tract, known as capacitation. Capacitation involves several molecular events such as phosphorylation cascades, hyperpolarization...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-31557-5
更新日期:2018-09-06 00:00:00
abstract::The insect membrane-protein, Torso, is a member of the receptor-tyrosine-kinase family, and is activated by its ligand, prothoracicotropic hormone (PTTH). Although PTTH is one of the most important regulators of insect development, the mechanism of Torso activation by the hormone has remained elusive. In this study, u...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep22437
更新日期:2016-03-01 00:00:00
abstract::The stress distribution around endosseous implants is an important determinant of the surgical success. However, no method developed so far to determine the implant stability is sensitive to the loading conditions of the bone-implant interface (BII). The objective of this study is to investigate whether a quantitative...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-50665-4
更新日期:2019-10-02 00:00:00
abstract::It is shown that in the ergodic regime, the temperature dependence of Young's modulus is solely determined by the magnetic properties of a material. For the large class of materials with paramagnetic or diamagnetic response, simple functional forms of the temperature derivative of Young's modulus are derived and compa...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-05238-8
更新日期:2017-07-07 00:00:00
abstract::State of charge (SOC) is a crucial index used in the assessment of electric vehicle (EV) battery storage systems. Thus, SOC estimation of lithium-ion batteries has been widely investigated because of their fast charging, long-life cycle, and high energy density characteristics. However, precise SOC assessment of lithi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-61464-7
更新日期:2020-03-13 00:00:00
abstract::Bronchospasm compresses the bronchial epithelium, and this compressive stress has been implicated in asthma pathogenesis. However, the molecular mechanisms by which this compressive stress alters pathways relevant to disease are not well understood. Using air-liquid interface cultures of primary human bronchial epithe...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-57755-8
更新日期:2020-01-22 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-020-69600-z
更新日期:2020-07-22 00:00:00
abstract::Mind wandering (MW) refers to the disengagement of attention from the external environment and the generation of thoughts unrelated to the task at hand. It is a ubiquitous cognitive process resulting in lapses of attention. MW imposes a negative impact on attention-based task performance, but also has been associated ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-10616-3
更新日期:2017-08-31 00:00:00
abstract::Photodynamic therapy is attracting increasing attention, but how to increase its tumor-specificity remains a daunting challenge. Herein we report a theranostic probe (azo-PDT) that integrates pyropheophorbide α as a photosensitizer and a NIR fluorophore for tumor imaging. The two functionalities are linked with a hypo...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-68847-w
更新日期:2020-07-22 00:00:00
abstract::The development of bulk, three-dimensional (3D), macroporous polymers with high permeability, large surface area and large volume is highly desirable for a range of applications in the biomedical, biotechnological and environmental areas. The experimental techniques currently used are limited to the production of smal...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep21154
更新日期:2016-02-17 00:00:00
abstract::Nine new bicyclic cembranoids, sarcophytrols M-U(1-9), were isolated from the South China Sea soft coral Sarcophyton trocheliophorum as minor components, along with one known related cembranoid 10. Their structures were elucidated by detailed spectroscopic analysis and chemical conversion. The chemical structures of t...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep46584
更新日期:2017-04-21 00:00:00
abstract::The PDZ domain-containing scaffold protein, syntenin-1, binds to the transmembrane proteoglycan, syndecan-4, but the molecular mechanism/function of this interaction are unknown. Crystal structure analysis of syntenin-1/syndecan-4 cytoplasmic domains revealed that syntenin-1 forms a symmetrical pair of dimers anchored...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep36818
更新日期:2016-11-10 00:00:00
abstract::With the increasing amount of research work in surface studies, a more effective method of producing patterned microstructures is highly desired due to the geometric limitations and complex fabricating process of current techniques. This paper presents an efficient and cost-effective method to generate customizable mi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep21621
更新日期:2016-02-23 00:00:00
abstract::Hypoxia-induced retinal neovascularization is a major pathological condition in many vision-threatening diseases. In the present study, we determined whether interleukin (IL)-12, a cytokine that regulates angiogenesis, plays a role in the neovascularization in a mouse model of oxygen-induced retinopathy (OIR). We foun...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep28140
更新日期:2016-06-17 00:00:00
abstract::The association of visual impairment and depression has been investigated in several studies based on a cross-sectional design, which cannot delineate temporal relationships. In the present study, we evaluated the influence of visual impairment on depression in all age groups using a longitudinal database of a nationa...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-20374-5
更新日期:2018-02-01 00:00:00
abstract::Escherichia coli lac repressor (LacI) is a paradigmatic transcriptional factor that controls the expression of lacZYA in the lac operon. This tetrameric protein specifically binds to the O1, O2 and O3 operators of the lac operon and forms a DNA loop to repress transcription from the adjacent lac promoter. In this arti...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep19243
更新日期:2016-01-14 00:00:00
abstract::The systematics of Oriental freshwater mussels (Bivalvia: Unionidae) is poorly known. Here, we present an integrative revision of the genus Trapezoideus Simpson, 1900 to further understanding of freshwater mussel diversity in the region. We demonstrate that Trapezoideus as currently circumscribed is non-monophyletic, ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-39365-1
更新日期:2019-03-11 00:00:00