Abstract:
:An amendment to this paper has been published and can be accessed via a link at the top of the paper.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Yoshida S,Miyagawa S,Toyofuku T,Fukushima S,Kawamura T,Kawamura A,Kashiyama N,Nakamura Y,Toda K,Sawa Ydoi
10.1038/s41598-020-67129-9subject
Has Abstractpub_date
2020-06-17 00:00:00pages
10058issue
1issn
2045-2322pii
10.1038/s41598-020-67129-9journal_volume
10pub_type
已发布勘误abstract::Mycobacterium spp. are renowned for being the causative agent of diseases like leprosy, Buruli ulcer and tuberculosis in human beings. With more and more mycobacterial genomes being sequenced, any knowledge generated from comparative genomic analysis would provide better insights into the biology, evolution, phylogeny...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep18227
更新日期:2015-12-15 00:00:00
abstract::Light represents the principal signal driving circadian clock entrainment. However, how light influences the evolution of the clock remains poorly understood. The cavefish Phreatichthys andruzzii represents a fascinating model to explore how evolution under extreme aphotic conditions shapes the circadian clock, since ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-27080-2
更新日期:2018-06-08 00:00:00
abstract::A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-018-34062-x
更新日期:2018-10-29 00:00:00
abstract::Despite advances in stem cell research, cell transplantation therapy for liver failure is impeded by a shortage of human primary hepatocytes (HPH), along with current differentiation protocol limitations. Several studies have examined the concept of co-culture of human induced pluripotent cells (hiPSCs) with various t...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-45514-3
更新日期:2019-06-20 00:00:00
abstract::Spontaneous ultra-weak photon emission from living organisms, designated as biophoton emission, is a generally observed phenomenon irrespective of the organism species. Biophoton emission is attributed to the production of excited molecules in a metabolic biochemical reaction, especially in processes involving reactiv...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-45007-3
更新日期:2019-06-12 00:00:00
abstract::Agriculture provides livelihood for 65% of Nepal's population contributing for 27% of its GDP. Smallholder farms constitute 60% of farming segment. Distress farming, with inadequate minimum support price, subsidies and inadequate revenue generation force 29% of the general population to be malnourished. Farming system...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-67657-4
更新日期:2020-06-29 00:00:00
abstract::Diabetes is expected to accelerate age-related ganglion cell-inner plexiform layer (GC-IPL) loss, but there is limited information on the rate of reduction in GC-IPL thicknesses. We aimed to evaluate the reduction rate of GC-IPL thickness in diabetic patients, and to compare the rates between patients without and with...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-58465-x
更新日期:2020-01-30 00:00:00
abstract::Feedback information is essential for us to adapt appropriately to the environment. The feedback-related negativity (FRN), a frontocentral negative deflection after the delivery of feedback, has been found to be larger for outcomes that are worse than expected, and it reflects a reward prediction error derived from th...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep34032
更新日期:2016-10-03 00:00:00
abstract::Central visual field (CVF) loss has been linked to poorer vision-related quality of life in eyes with open-angle glaucoma (OAG) and can occur even in early-stage OAG eyes. The present study investigated whether the detection of choroidal microvasculature dropout (CMvD) during follow-up, which may be a sign of perfusio...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-44942-5
更新日期:2019-06-12 00:00:00
abstract::Next generation sequencing is transforming clinical medicine and genome research, providing a powerful route to establishing molecular diagnoses for genetic conditions; however, challenges remain given the volume and complexity of genetic variation. A number of methods integrate patient phenotype and genotypic data to...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-13841-y
更新日期:2017-10-18 00:00:00
abstract::Sweet potato is an important food and bio-energy crop, and investigating the mechanisms underlying salt tolerance will provide information for salt-tolerant breeding of this crop. Here, the root transcriptomes of the salt-sensitive variety Lizixiang and the salt-tolerant line ND98 were compared to identify the genes a...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep40819
更新日期:2017-01-13 00:00:00
abstract::Capable of generating plasmonic and other effects, gold nanostructures can offer a variety of diagnostic and therapy functionalities for biomedical applications, but conventional chemically-synthesized Au nanomaterials cannot always match stringent requirements for toxicity levels and surface conditioning. Laser-synth...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-48748-3
更新日期:2019-09-09 00:00:00
abstract::Laparoscopic cholecystectomy (LC) is the standard technique for treatment of gallbladder disease. In case of acute cholecystitis we can identify preoperative factors associated with an increased risk of conversion and intraoperative complications. The aim of our study was to detect preoperative laboratory and radiolog...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-81938-6
更新日期:2021-01-28 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-020-65026-9
更新日期:2020-05-20 00:00:00
abstract::HUWE1 is a HECT domain containing ubiquitin ligase implicated in neurogenesis, spermatogenesis and cancer development. The purpose of the current study is to investigate the role of HUWE1 in early embryo development. Here we demonstrate that Huwe1 is expressed in both nucleus and cytoplasm of preimplantation mouse emb...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep37928
更新日期:2016-11-30 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-020-60882-x
更新日期:2020-03-02 00:00:00
abstract::Medulloblastoma (MB), the most common malignant paediatric brain tumour occurs in the cerebellum. Advances in molecular genomics have led to the identification of defined subgroups which are associated with distinct clinical prognoses. Despite this classification, standard therapies for all subgroups often leave child...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-44950-5
更新日期:2019-06-13 00:00:00
abstract::Reef-building corals depend on an intracellular symbiosis with photosynthetic dinoflagellates for their survival in nutrient-poor oceans. Symbionts are phagocytosed by coral larvae from the environment and transfer essential nutrients to their hosts. Aiptasia, a small tropical marine sea anemone, is emerging as a trac...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-34773-1
更新日期:2018-11-06 00:00:00
abstract::The incidence and mortality of primary liver cancer are very high and resection of tumor is the most crucial treatment for it. We aimed to assess the efficacy and safety of combined use of transversus abdominis plane (TAP) block and laryngeal mask airway (LMA) during implementing Enhanced Recovery After Surgery (ERAS)...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-71477-x
更新日期:2020-09-10 00:00:00
abstract::Ossification of the posterior longitudinal ligament (OPLL) can occur throughout the entire spine and can sometimes lead to spinal disorder. Although patients with OPLL sometimes develop physical limitations because of pain, the characteristics of pain and effects on activities of daily living (ADL) have not been preci...
journal_title:Scientific reports
pub_type: 杂志文章,多中心研究
doi:10.1038/s41598-020-62278-3
更新日期:2020-03-26 00:00:00
abstract::Umami taste perception indicates the presence of amino acids, which are essential nutrients. Although the physiology of umami perception has been described in mammals, how insects detect amino acids remains unknown except in Drosophila melanogaster. We functionally characterized a gustatory receptor responding to L-am...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-46738-z
更新日期:2019-08-12 00:00:00
abstract::Multiple predatory insect lineages have developed a raptorial lifestyle by which they strike and hold prey using modified forelegs armed with spine-like structures and other integumentary specialisations. However, how structures enabling the raptorial function evolved in insects remains largely hypothetical or inferre...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-49398-1
更新日期:2019-09-13 00:00:00
abstract::Because histologic types are subjective and difficult to reproduce between pathologists, tissue morphology often takes a back seat to molecular testing for the selection of breast cancer treatments. This work explores whether a deep-learning algorithm can learn objective histologic H&E features that predict the clinic...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-64156-4
更新日期:2020-04-29 00:00:00
abstract::Inhibition of DYRK1A kinase, produced by chromosome 21 and consequently overproduced in trisomy 21 subjects, has been suggested as a therapeutic approach to treating the cognitive deficiencies observed in Down syndrome (DS). We now report the synthesis and potent DYRK1A inhibitory activities of fluoro derivatives of 3...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-20984-z
更新日期:2018-02-12 00:00:00
abstract::Extensive research indicates that inter-sexual selection drives the evolution of complex vocal communication in birds, but parallel lines of evidence are almost entirely absent in mammals. This dearth of evidence, particularly among primates, limits our understanding of the link between sociality and vocal complexity....
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep19680
更新日期:2016-01-21 00:00:00
abstract::Here, we describe a new strategy that allows the rapid and efficient engineering of mono and multispecific trivalent antibodies. By fusing single-domain antibodies from camelid heavy-chain-only immunoglobulins (VHHs) to the N-terminus of a human collagen XVIII trimerization domain (TIE(XVIII)) we produced monospecific...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep28643
更新日期:2016-06-27 00:00:00
abstract::We recently showed that spinal cord injury (SCI) leads to a decrease in mRNA editing of serotonin receptor 2C (5-HT2CR) contributing to post-SCI spasticity. Here we study post-SCI mRNA editing and global gene expression using massively parallel sequencing. Evidence is presented that the decrease in 5-HT2CR editing is ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep12615
更新日期:2015-07-30 00:00:00
abstract::Some insect galls are formed on sumac plants by certain aphid species and have been used for medicinal and chemical purposes as they are rich in tannins. The most prominent species among gall aphids in China is Schlechtendalia chinensis, which formed horn-shaped galls on the winged rachis of Rhus chinensis. S. chinens...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-06806-8
更新日期:2017-07-25 00:00:00
abstract::The restoration of dentine lost in deep caries lesions in teeth is a routine and common treatment that involves the use of inorganic cements based on calcium or silicon-based mineral aggregates. Such cements remain in the tooth and fail to degrade and thus normal mineral volume is never completely restored. Here we de...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep39654
更新日期:2017-01-09 00:00:00
abstract::We report, for the first time, that the energy of femtosecond optical laser pulses, E, with relativistic intensities I > 10(21) W/cm(2) is efficiently converted to X-ray radiation, which is emitted by "hot" electron component in collision-less processes and heats the solid density plasma periphery. As shown by direct...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep13436
更新日期:2015-09-02 00:00:00