Abstract:
PURPOSE OF REVIEW:Sickle cell disease (SCD) is a hematological disorder which leads to serious complications in multiple organ systems. While significant research has addressed many of the effects of acute pain episodes and end-organ damage connected to this disease, little has approached the chronic pain state associated with this condition. RECENT FINDINGS:Associated chronic pain represents a significant detractor from the quality of life experienced by these patients, affecting over half of those with SCD on more days than not. Current treatment typically is centered upon preventing and responding to acute vasoocclusive crises, presumably because this is the most common reason for hospitalization in these patients. The lack of management of chronic pain symptoms leaves many with SCD in a state of suffering. In this review, the treatment methodologies of SCD patients are examined including alternative treatments, both pharmaceutical and non-pharmaceutical, as well as procedural approaches specifically aimed at reducing chronic pain in these patients.
journal_name
Curr Pain Headache Repjournal_title
Current pain and headache reportsauthors
Fiocchi J,Urits I,Orhurhu V,Orhurhu MS,Giacomazzi S,Hoyt B,Kaye AD,Kaye RJ,Viswanath Odoi
10.1007/s11916-020-00854-ysubject
Has Abstractpub_date
2020-03-21 00:00:00pages
17issue
5eissn
1531-3433issn
1534-3081pii
10.1007/s11916-020-00854-yjournal_volume
24pub_type
杂志文章,评审abstract::Migraine and cluster headache have been considered entirely separate clinical syndromes, both in routine clinical practice and in the 1988 International Headache Society classification. Neurologists seeing large numbers of patients soon realize, however, that there is a considerable overlap between the two conditions....
journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
doi:10.1007/s11916-001-0012-3
更新日期:2001-02-01 00:00:00
abstract:PURPOSE OF REVIEW:CGRP is a key neuropeptide in migraine pathophysiology. The blockade of the CGRP pathway at the side of the CGRP receptor of the CGRP peptide leads to the interruption of trigeminal nerve system-mediated headache syndromes such as migraine. Monoclonal antibodies (mAbs) targeting the CGRP pathway have ...
journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
doi:10.1007/s11916-018-0686-4
更新日期:2018-04-06 00:00:00
abstract::Ultrasound plays a significant role in the diagnosis and treatment of pain, with significant literature reaching back many years, especially with regard to diagnostic ultrasound and its use for guiding needle-based delivery of drugs. Advances in ultrasound over at least the last decade have opened up new areas of inqu...
journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
doi:10.1007/s11916-018-0711-7
更新日期:2018-07-10 00:00:00
abstract::Complementary medical therapies are commonly used for the treatment and management of myofascial pain. No universally accepted therapy for this condition exists; consequently, patients often seek alternative and complementary therapies. Many complementary treatments are available.This article focuses on acupuncture, b...
journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
doi:10.1007/s11916-002-0078-6
更新日期:2002-10-01 00:00:00
abstract::Over the last few years, attention has increasingly been focused on the evolution of cluster headache over time. Predictive factors have been identified that are correlated with an increased risk of unfavorable evolution from the episodic form to the chronic form of cluster headache. Late onset, the presence of sporad...
journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
doi:10.1007/s11916-002-0026-5
更新日期:2002-02-01 00:00:00
abstract:PURPOSE OF REVIEW:This review highlights the importance of osteopathic manipulative treatment (OMT) in headache sufferers. OMT is a viable option for patients who either do not wish to use pharmaceuticals or who have contraindications to pharmaceuticals. Patients with headaches that are refractory to other treatment op...
journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
doi:10.1007/s11916-018-0736-y
更新日期:2018-10-05 00:00:00
abstract::Myofascial pain syndrome (MPS) is a common chronic pain condition that is characterized by distinct "trigger points." Despite current treatments with physical therapy, analgesics, anti-depressants and trigger-point injections, myofascial pain remains a challenging chronic pain condition in clinical practice. Botulinum...
journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
doi:10.1007/s11916-013-0386-z
更新日期:2014-01-01 00:00:00
abstract::Caffeine is the most widely consumed psychostimulant drug in the world. With intermittent exposures, caffeine may act as a mild analgesic for headache or as an adjuvant for the actions of other analgesics. Chronic repetitive exposures to caffeine increase the risks for development of analgesic-overuse headache, chroni...
journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
doi:10.1007/s11916-008-0052-z
更新日期:2008-08-01 00:00:00
abstract:PURPOSE OF REVIEW:Neuropathic pain is often debilitating, severely limiting the daily lives of patients who are affected. Typically, neuropathic pain is difficult to manage and, as a result, leads to progression into a chronic condition that is, in many instances, refractory to medical management. RECENT FINDINGS:Gaba...
journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
doi:10.1007/s11916-019-0774-0
更新日期:2019-05-01 00:00:00
abstract::While pain is a common symptom among older adults, it often is underdiagnosed and undertreated. Aging-related physiological changes, misperceptions about the use of pain medications by both patients and providers, and the lack of evidence-based clinical research on pain management in older adults are some of the reaso...
journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
doi:10.1007/s11916-010-0148-0
更新日期:2010-12-01 00:00:00
abstract::Health care professionals caring for neonates (birth to 28 days of life) and infants up to 1 year of age have a professional and ethical responsibility to provide safe and effective pain management during painful procedures. Despite 14 years of research reports highlighting that sick infants are exposed to large numbe...
journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
doi:10.1007/s11916-009-0091-0
更新日期:2010-04-01 00:00:00
abstract::Patients with fibromyalgia (FM) frequently have gastrointestinal symptoms and signs. This article critically reviews the available literature and concludes the following: evidence that inflammatory bowel disease is associated with FM is contradictory, but should be looked for in patients taking concomitant steroids; p...
journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
doi:10.1007/s11916-996-0009-z
更新日期:2004-10-01 00:00:00
abstract::Migraine and tension-type headache (TTH) are highly prevalent primary headaches that remain underdiagnosed and undertreated in clinical practice. The similarities and differences between migraine and TTH may impose diagnostic challenges as well as management difficulties. In addition, the possibility of migraine chron...
journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
doi:10.1007/s11916-007-0232-2
更新日期:2007-12-01 00:00:00
abstract::Pediatric and adolescence headache is one of the most common causes of access in emergency departments (ED). Primary headache and headache secondary to self-limited conditions are the majority of cases. Secondary life-threatening headaches are less frequent and may be recognized by a careful history and physical exami...
journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
doi:10.1007/s11916-015-0480-5
更新日期:2015-03-01 00:00:00
abstract::Chemotherapy-induced peripheral neuropathy (CIPN) is a major concern in oncology practice given the increasing number of cancer survivors and the lack of effective treatment. The incidence of peripheral neuropathy depends upon the anticancer drug used, but is commonly under-reported in clinical trials. Several animal ...
journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
doi:10.1007/s11916-013-0364-5
更新日期:2013-10-01 00:00:00
abstract:PURPOSE OF REVIEW:Fibromyalgia (FM) is the second most common rheumatologic pain disorder after osteoarthritis with a multisystem presentation. While the treatment of FM in a clinical setting incorporates both pharmacologic and non-pharmacologic modalities, the present investigation reviews evolving literature on cogni...
journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
doi:10.1007/s11916-018-0688-2
更新日期:2018-04-04 00:00:00
abstract::Weight gain is a common side effect of drugs used for headache prevention. Weight gain can adversely affect patient health, exacerbate comorbid metabolic disorders, and encourage noncompliance. Additionally, obesity may promote the chronification of episodic migraine. Few studies have looked specifically at the effect...
journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
doi:10.1007/s11916-008-0035-0
更新日期:2008-06-01 00:00:00
abstract::Hyperprolactinemia is a condition characterised by an increase of prolactin blood levels (more than 100-200 ng/ml). It is the most common endocrine disorder of the hypothalamic-pituitary axis. The clinical characteristics of the headache-hyperprolactinemia-hypophyseal-adenoma association are discussed, the various dia...
journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
doi:10.1007/s11916-012-0267-x
更新日期:2012-08-01 00:00:00
abstract::Empathy is a provider attribute that has been a topic of increased clinical interest, particularly as it relates to pain. This article examines various dimensions of the pain and empathy literature: definitions of empathy, research regarding the psychophysiology of empathy for pain, and research related to empathy in ...
journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
doi:10.1007/s11916-008-0021-6
更新日期:2008-04-01 00:00:00
abstract::Clinical understanding and management of myofascial pain is overlooked frequently when dealing with pain. Myofascial pain is defined as pain or autonomic phenomena referred from active trigger points, with associated dysfunction. The trigger point is a focus of hyperirritability in the muscle that, when compressed, is...
journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
doi:10.1007/s11916-004-0068-y
更新日期:2004-12-01 00:00:00
abstract::Tension type headache (TTH) is a primary headache disorder considered common in children and adolescents. It remains debatable whether TTH and migraine are separate biological entities. This review summarizes the most recent literature of TTH with regards to children and adolescents. Further studies of TTH are needed ...
journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
doi:10.1007/s11916-010-0149-z
更新日期:2010-12-01 00:00:00
abstract::In the past decades investigators have used personality inventories to help explain the relationship between personality and pain experience. This article reviews empirical research, which has examined temperament and character features in chronic pain patients. Robert Cloninger's temperament and character model of pe...
journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
doi:10.1007/s11916-012-0318-3
更新日期:2013-03-01 00:00:00
abstract::The association of traumatic exposures with posttraumatic stress disorder (PTSD) and other mental health conditions is well known. Patients with chronic pain, particularly headache disorders and fibromyalgia (FM), associated with psychological traumas need a special management strategy. Diagnosis of headache disorders...
journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
doi:10.1007/s11916-009-0057-2
更新日期:2009-10-01 00:00:00
abstract:PURPOSE OF REVIEW:To identify the efficacy of radiofrequency ablation of pericranial nerves in treating headache. RECENT FINDINGS:Recent studies by the same group showed promising results in treating headache using radiofrequency ablation. Pericranial nerves can be a therapeutic target for treating headache. Our resul...
journal_title:Current pain and headache reports
pub_type: 杂志文章
doi:10.1007/s11916-020-0843-4
更新日期:2020-03-12 00:00:00
abstract::Addiction to opioid analgesics is an important and yet underinvestigated clinical issue, which has substantial implications in opioid therapy for chronic pain management. Problematic opioid use, including compulsive opioid seeking and addiction, arises in some fraction of opioid-treated chronic pain patients. The conn...
journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
doi:10.1007/s11916-009-0086-x
更新日期:2010-02-01 00:00:00
abstract:PURPOSE OF REVIEW:The purpose of the present systematic review is to provide a current understanding of the mechanism of action and the evidence available to support clinical decision-making. The focus is to summarize randomized controlled trials (RCTs) and nonrandomized or observational studies of spinal cord stimulat...
journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
doi:10.1007/s11916-020-00907-2
更新日期:2020-09-30 00:00:00
abstract:PURPOSE OF REVIEW:Total knee arthroplasty traditionally has been associated with significant postoperative pain that can limit recovery and prolong hospital length of stay. Recently, however, due to financial pressures and an emphasis on improving patient satisfaction, many institutions are implementing outpatient and ...
journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
doi:10.1007/s11916-017-0623-y
更新日期:2017-05-01 00:00:00
abstract::Myofascial pain syndrome (MPS) is caused by myofascial trigger points (MTrPs) located within taut bands of skeletal muscle fibers. Treating the underlying etiologic lesion responsible for MTrP activation is the most important strategy in MPS therapy. If the underlying pathology is not given the appropriate treatment, ...
journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
doi:10.1007/s11916-006-0058-3
更新日期:2006-10-01 00:00:00
abstract:: ...
journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
doi:10.1007/s11916-019-0746-4
更新日期:2019-01-19 00:00:00
abstract::Neuropathic pain remains a serious medical problem because of patient morbidity and the absence of effective therapeutic interventions. Recent evidence suggests that this type of pain may be particularly difficult to manage because underlying mechanisms are influenced by a variety of factors, including type of injury,...
journal_title:Current pain and headache reports
pub_type: 杂志文章,评审
doi:10.1007/s11916-009-0034-9
更新日期:2009-06-01 00:00:00