Pragmatic consideration of recent randomized, placebo-controlled clinical trials for treatment of fibromyalgia.

Abstract:

:A flurry of recent randomized, placebo-controlled trials assessing dissimilar pharmacotherapeutic treatment options for fibromyalgia (FM) have been presented in the past few years. This review evaluates these trials in light of recent pathophysiological concepts germane to FM, including mood disorders, autonomic dysregulation, altered sleep stage architecture, and the diagnostic tender point controversy. Studies with gabapentin, pregabalin, duloxetine, milnacipran, sodium oxybate, and pramipexole for treatment of FM are discussed.

journal_name

Curr Pain Headache Rep

authors

Holman AJ

doi

10.1007/s11916-008-0067-5

subject

Has Abstract

pub_date

2008-12-01 00:00:00

pages

393-8

issue

6

eissn

1531-3433

issn

1534-3081

journal_volume

12

pub_type

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