当前位置： SCI文献检索 > Journal of Global Antimicrobial Resistance期刊下所有文献 > Genotypic and phylogenetic characterisation of a clinical Ralstonia pickettii strain carrying two novel OXA allelic variants, blaOXA-898 and blaOXA-899, isolated from a bloodstream infection in China.

Genotypic and phylogenetic characterisation of a clinical Ralstonia pickettii strain carrying two novel OXA allelic variants, blaOXA-898 and blaOXA-899, isolated from a bloodstream infection in China.

Abstract：

OBJECTIVES:Ralstonia pickettii has been increasingly recognised as an emerging opportunistic pathogen in hospital settings in recent years, especially in patients with prolonged hospital stay. Clinical manifestations associated with R. pickettii infection range from mild infections to severe invasive life-threatening infections. Here we report the genome sequence of a clinical R. pickettii strain (PSLESD1) carrying two novel blaOXA allelic variants in China. METHODS:Whole-genome sequencing of strain PSLESD1 was performed using an Illumina NovaSeq 6000 platform. Antimicrobial resistance genes were identified using the BacWGSTdb server. The phylogenetic relationship betweenR. pickettii PSLESD1 and a total of 17 R. pickettii strains deposited in the NCBI GenBank database was analysed using NJ (neighbour joining)/UPGMA (unweighted pair-group method with arithmetic mean) phylogeny (MAFFT v.7) based on core genome single nucleotide polymorphism (SNP) data. RESULTS:The draft genome sequence of R. pickettii strain PSLESD1 consists of 25 contigs comprising 5 267 333 bp. Three antimicrobial resistance genes were identified in the genome, including blaOXA-898, blaOXA-899 and sul2. Strain PSLESD1 was resistant to aminoglycosides and carbapenems including meropenem. Phylogenetic analysis showed that all strains retrieved from the NCBI GenBank database were epidemiologically unrelated. The closest relative of strain PSLESD1 was H2Cu2, which differed by 2908 SNPs. CONCLUSION:In summary, we report the first genome sequence of a clinicalR. pickettii strain harbouring two novel class D β-lactamase genes (blaOXA-898 and blaOXA-899) recovered from a bloodstream infection in China. These data may help to understand the genomic features and antimicrobial resistance mechanisms of this bacterial pathogen.

journal_name

J Glob Antimicrob Resist

journal_title

Journal of global antimicrobial resistance

authors

Jiang T,Xu J,He F

doi

10.1016/j.jgar.2020.02.020

subject

Has Abstract

pub_date

2020-06-01 00:00:00

pages

46-48

eissn

2213-7165

issn

2213-7173

pii

S2213-7165(20)30049-7

journal_volume

21

pub_type

杂志文章

相关文献

Journal of Global Antimicrobial Resistance文献大全
  • Draft genome sequence of a clinical Acinetobacter baumannii isolate of new sequence type ST1688 from Saudi Arabia.

    abstract：OBJECTIVES:Acinetobacter baumannii has emerged as a prevalent multidrug-resistant nosocomial pathogen worldwide. Here we report the draft genome sequence of A. baumannii strain Ab174 isolated from a neonatal patient diagnosed with acute peritonitis. METHODS:The draft genome sequence of A. baumannii Ab174 was determine...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2019.06.021

    authors： Yasir M,Shah MW,Jiman-Fatani AA,Almasaudi SB,Ahmad H,Alawi M,Azhar EI

    更新日期：2019-09-01 00:00:00

  • Urinary tract infection in Uruguayan children: Aetiology, antimicrobial resistance and uropathogenic Escherichia coli virulotyping.

    abstract：:Uropathogenic Escherichia coli (UPEC) is the most frequent cause of urinary tract infection (UTI). Virulence factors (VFs) of UPEC in children are not well known. Circulating antibiotic resistance mechanisms in the community are increasing. In this study, the aetiological agents of UTI and antibiotic resistance mechan...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2014.08.003

    authors： Robino L,García-Fulgueiras V,Araujo L,Algorta G,Pírez MC,Vignoli R

    更新日期：2014-12-01 00:00:00

  • Complete genome sequence of multidrug-resistant Staphylococcus cohnii ssp. urealyticus strain SNUDS-2 isolated from farmed duck, Republic of Korea.

    abstract：OBJECTIVES:Staphylococcus cohnii has become increasingly recognized as a potential pathogen of clinically significant nosocomial and farm animal infections. This study was designed to determine the genome of a multidrug-resistant S. cohnii subsp. urealyticus strain SNUDS-2 isolated from a farmed duck in Korea. METHODS...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2017.05.008

    authors： Han JE,Lee S,Jeong DG,Yoon SW,Kim DJ,Lee MS,Kim HK,Park SK,Kim JH,Park SC

    更新日期：2017-09-01 00:00:00

  • Genetic analysis of a PER-2-producing Shewanella sp. strain harbouring a variety of mobile genetic elements and antibiotic resistance determinants.

    abstract：:The objective of this study was to investigate the molecular mechanisms explaining the multidrug-resistant (MDR) phenotype found in a novel clinical Shewanella sp. strain (Shew256) recovered from a diabetic patient. Whole-genome shotgun sequencing was performed using Illumina MiSeq-I and Nextera XT DNA library. De nov...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2017.06.005

    authors： Almuzara M,Montaña S,Lazzaro T,Uong S,Parmeciano Di Noto G,Traglia G,Bakai R,Centrón D,Iriarte A,Quiroga C,Ramirez MS

    更新日期：2017-12-01 00:00:00

  • Basis for a cheap method for detecting bacteria and assessing their antibiotic susceptibility in urine samples.

    abstract：:Although molecular methods can now provide fast identification and the antibiotic susceptibility profile of infecting pathogens, these techniques are not affordable by a large majority of clinical laboratories in developing countries and can be considered excessive for simple, community-acquired infections. Most antib...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2013.01.001

    authors： Amábile-Cuevas CF

    更新日期：2013-03-01 00:00:00

  • Complete genome arrangement revealed the emergence of a poultry origin superbug Citrobacter portucalensis strain NR-12.

    abstract：OBJECTIVES:Citrobacter spp. are part of normal human and animal intestinal flora. Citrobacter portucalensis (C. portucalensis) is closely related to Citrobacter freundii, which is an emerging opportunistic nosocomial pathogen. The aim of this study was to retrieve colistin-resistant Citrobacter spp. from poultry in Ban...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2019.05.031

    authors： Hasan MS,Sultana M,Hossain MA

    更新日期：2019-09-01 00:00:00

  • Carbapenem-resistant Klebsiella pneumoniae infections in a Greek intensive care unit: Molecular characterisation and treatment challenges.

    abstract：:Acquisition of carbapenemase-producing Klebsiella pneumoniae (CP-Kp) strains poses a major threat to critically ill patients. The objectives of this study were to describe the epidemiology of CP-Kp isolates as well as the clinical outcome associated with the corresponding infections and to identify risk factors for mo...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2015.01.006

    authors： Katsiari M,Panagiota G,Likousi S,Roussou Z,Polemis M,Alkiviadis Vatopoulos C,Evangelia Platsouka D,Maguina A

    更新日期：2015-06-01 00:00:00

  • Influence of age on the clinical efficacy of tigecycline in severely ill patients.

    abstract：OBJECTIVES:The aim of this study was to define the relationship between age and response to tigecycline among patients treated for complicated skin and soft-tissue infections (cSSTIs) and complicated intra-abdominal infections (cIAIs). METHODS:Pooled data derived from five European observational studies on the use of ...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2019.03.018

    authors： Bassetti M,Guirao X,Montravers P,Rossolini GM,Sánchez García M,Sganga G,Eckmann C

    更新日期：2019-09-01 00:00:00

  • Genetic characterisation of a whiB7 mutant of a Mycobacterium tuberculosis clinical strain.

    abstract：:Mycobacterium tuberculosis is naturally resistant to clarithromycin (CLR). The genes Rv3197A (whiB7) and Rv1988 (ermMT) have been shown to be involved in the resistant phenotype. In this study, a CLR-susceptible M. tuberculosis clinical strain was identified, designated as DS3214, and the nucleotide sequences and expr...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2015.07.004

    authors： Warit S,Phunpruch S,Jityam C,Jaitrong S,Billamas P,Chaiprasert A,Palittapongarnpim P,Prammananan T

    更新日期：2015-12-01 00:00:00

  • Draft genome sequence of a multidrug-resistant KPC-2-producing Enterobacter aerogenes isolated from a hospitalised patient in Brazil.

    abstract：OBJECTIVES:Multidrug-resistant (MDR) Enterobacter aerogenes strains are frequently associated with nosocomial infections and high mortality rates, representing a serious public health problem. The aim of this study was to present the draft genome sequence of a MDR KPC-2-producing E. aerogenes isolated from a perineal s...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2017.07.016

    authors： Moura Q,Fernandes MR,Cerdeira L,Nhambe LF,Ienne S,Souza TA,Lincopan N

    更新日期：2017-09-01 00:00:00

  • Evaluation of vancomycin MIC creep in Staphylococcus aureus.

    abstract：OBJECTIVES:Vancomycin is the primary treatment for methicillin-resistant Staphylococcus aureus (MRSA). However, an increasing proportion of MRSA isolates with high minimum inhibitory concentrations (MICs) within the susceptible range (vancomycin 'MIC creep') is being observed. The aim of this study was to assess the va...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2017.04.007

    authors： Diaz R,Ramalheira E,Afreixo V,Gago B

    更新日期：2017-09-01 00:00:00

  • Evolutionary rescue of bacteria via horizontal gene transfer under a lethal β-lactam concentration.

    abstract：:β-Lactams are a commonly used class of bactericidal antibiotics. The number of β-lactam-resistant pathogens is constantly increasing in hospitals around the world. Interestingly, most of the β-lactam-resistant bacteria carry mobile genetic elements, such as conjugative plasmids, that render the pathogen resistant. The...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2014.02.005

    authors： Ojala V,Mattila S,Hoikkala V,Bamford JK,Jalasvuori M

    更新日期：2014-09-01 00:00:00

  • Multidrug-resistant Klebsiella quasipneumoniae subsp. similipneumoniae carrying blaNDM-blaCTX-M15 isolated from flies in Rio de Janeiro, Brazil.

    abstract：OBJECTIVES:Flies have been implicated in the dispersal of medically important bacteria including members of the genus Klebsiella between different environmental compartments. The aim of this study was to retrieve and characterize antibiotic-resistant bacteria from flies collected near to hospitals. METHODS:Flies were ...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2020.11.021

    authors： Carramaschi IN,Dos S B Ferreira V,Chagas TPG,Corrêa LL,Picão RC,de C Queiroz MM,Rangel K,Jardim R,da Mota FF,Zahner V

    更新日期：2020-12-07 00:00:00

  • Genomic analysis of two bacterial strains co-isolated from a urinary tract infection: NDM-1-producing Enterobacter cloacae accompanied by extended-spectrum β-lactamase-producing Escherichia coli.

    abstract：OBJECTIVES:Escherichia coli and Enterobacter cloacae are two major pathogens causing urinary tract infection (UTI). Here we characterised the genome of an NDM-1-producing E. cloacae strain and an extended-spectrum β-lactamase (ESBL)-producing E. coli strain that were co-isolated from a UTI. METHODS:The genomes of E. c...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2019.04.007

    authors： Xu J,He F

    更新日期：2019-06-01 00:00:00

  • Clinical epidemiology of vancomycin-resistant Enterococcus gallinarum and Enterococcus casseliflavus bloodstream infections.

    abstract：:This study aimed to evaluate the clinical outcomes of vancomycin-resistant enterococcal bloodstream infections (VRE BSI) caused by Enterococcus gallinarum or Enterococcus casseliflavus. Variables associated with treatment failure were determined and treatment options were compared. This was a national retrospective st...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2015.12.002

    authors： Britt NS,Potter EM

    更新日期：2016-06-01 00:00:00

  • Novel R-plasmid conjugal transfer inhibitory and antibacterial activities of phenolic compounds from Mallotus philippensis (Lam.) Mull. Arg.

    abstract：:Antimicrobial resistance severely limits the therapeutic options for many clinically important bacteria. In Gram-negative bacteria, multidrug resistance is commonly facilitated by plasmids that have the ability to accumulate and transfer refractory genes amongst bacterial populations. The aim of this study was to isol...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2016.01.011

    authors： Oyedemi BO,Shinde V,Shinde K,Kakalou D,Stapleton PD,Gibbons S

    更新日期：2016-06-01 00:00:00

  • In vitro activity of fosfomycin against mucoid and non-mucoid Pseudomonas aeruginosa strains.

    abstract：OBJECTIVES:Pseudomonas aeruginosa is the most frequent infectious agent in cystic fibrosis patients. P. aeruginosa resistance to first line antibiotics limits therapeutic options, but the therapeutic potential of older generation antibiotics, such as fosfomycin is under investigation. Fosfomycin does not belong to any ...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2020.02.014

    authors： Bressan A,Rodio DM,Stangherlin F,Puggioni G,Ambrosi C,Arcari G,Carattoli A,Antonelli G,Pietropaolo V,Trancassini M

    更新日期：2020-03-01 00:00:00

  • Characterisation of clinical canine meticillin-resistant and meticillin-susceptible Staphylococcus pseudintermedius in France.

    abstract：:Staphylococcus pseudintermedius is a frequent pathogen in dogs. The emergence of meticillin-resistant S. pseudintermedius (MRSP), which is concomitantly resistant to nearly all veterinary licensed antibiotics used for systemic treatment in dogs, is a major problem for veterinarians. In France, 16.9% (41/243) of the S....

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2014.02.002

    authors： Haenni M,de Moraes NA,Châtre P,Médaille C,Moodley A,Madec JY

    更新日期：2014-06-01 00:00:00

  • Antimicrobial resistance and the current refugee crisis.

    abstract：:In the past few years, Europe has experienced an enormous influx of refugees and migrants owing to the ongoing civil war in Syria as well as conflicts, violence and instability in other Asian and African countries. Available data suggest that refugees carry a significant burden of multidrug-resistant (MDR) organisms, ...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章,评审

    doi：10.1016/j.jgar.2017.03.013

    authors： Maltezou HC,Theodoridou M,Daikos GL

    更新日期：2017-09-01 00:00:00

  • Antimicrobial resistance patterns of uropathogens isolated between 2012 and 2017 from a tertiary hospital in Northern Ethiopia.

    abstract：OBJECTIVES:Urinary tract infections (UTIs) are one of the most common infections in humans. Studies have shown that antibiotics for UTIs are usually prescribed empirically before the results of urine culture are available. The aim of the study was to assess the antimicrobial resistance patterns of bacteria isolated fro...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2019.01.022

    authors： Tuem KB,Desta R,Bitew H,Ibrahim S,Hishe HZ

    更新日期：2019-09-01 00:00:00

  • Predictors of death among drug-resistant tuberculosis patients in Kuala Lumpur, Malaysia: A retrospective cohort study from 2009 to 2013.

    abstract：:The emergence of drug-resistant tuberculosis (TB) is a major public health threat. However, little is known about the predictors of death in drug-resistant TB in Malaysia. This study aimed to determine the predictors of death in drug-resistant TB patients, including multidrug-resistant TB (MDR-TB), in Kuala Lumpur, Ma...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2016.04.005

    authors： Mohd Shariff N,Shah SA,Kamaludin F

    更新日期：2016-09-01 00:00:00

  • Emergence of an Escherichia coli strain co-harbouring mcr-1 and blaNDM-9 from a urinary tract infection in Taiwan.

    abstract：OBJECTIVES:Multidrug-resistant bacteria have become a serious threat worldwide. In particular, the coexistence of carbapenemase genes and mcr-1 leaves few available treatment options. Here we report a multidrug-resistant Escherichia coli isolate harbouring both mcr-1 and blaNDM-9 from a patient with a urinary tract inf...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2018.10.003

    authors： Lin YC,Kuroda M,Suzuki S,Mu JJ

    更新日期：2019-03-01 00:00:00

  • Interaction of carbapenems and β-lactamase inhibitors towards CTX-M-15 and CTX-M-15G238C mutant.

    abstract：OBJECTIVES:The aim of this study was to evaluate the role of residue 238 in CTX-M-15 and CTX-M-15G238C mutant with respect to carbapenems and various β-lactamase inhibitors. METHODS:A CTX-M-15G238C laboratory mutant was generated by site-directed mutagenesis from CTX-M-15 enzyme by replacing glycine 238 with cysteine....

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2017.04.004

    authors： Sabatini A,Brisdelli F,Celenza G,Marcoccia F,Colapietro M,Tavío MM,Piccirilli A,Amicosante G,Perilli M

    更新日期：2017-09-01 00:00:00

  • Risk factors for carbapenem-resistant Klebsiella pneumoniae infection: A meta-analysis.

    abstract：OBJECTIVES:Rates of nosocomial infections caused by carbapenem-resistant Klebsiella pneumoniae (CRKP) have increased. A meta-analysis was conducted to explore risk factors for CRKP infection in order to provide a theoretical basis for reducing the CRKP infection rate and actively preventing CRKP infection. METHODS:Onl...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2019.09.006

    authors： Li J,Li Y,Song N,Chen Y

    更新日期：2020-06-01 00:00:00

  • Antimicrobial stewardship in hospitals: Does it work and can we do it?

    abstract：:Selection of resistant pathogens by antimicrobial use is probably the most important cause of antimicrobial resistance. Antimicrobial stewardship (AMS) refers to a multifaceted approach to optimise prescribing. The benefits of AMS programmes have been widely demonstrated in terms of reductions in antimicrobial use, mo...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章,评审

    doi：10.1016/j.jgar.2013.08.001

    authors： Levy Hara G

    更新日期：2014-03-01 00:00:00

  • Antimicrobial resistance profiles and genotypes of extended-spectrum β-lactamase- and AmpC β-lactamase-producing Klebsiella pneumoniae isolated from dogs in Beijing, China.

    abstract：OBJECTIVES:Klebsiella pneumoniae, which exists in the intestinal and respiratory tracts of humans and animals, is an important conditional pathogen in many animals. The aim of the current study was to investigate the antimicrobial resistance profiles and genotypes of extended-spectrum β-lactamase (ESBL)- and AmpC β-lac...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2017.06.006

    authors： Liu Y,Yang Y,Chen Y,Xia Z

    更新日期：2017-09-01 00:00:00

  • Draft genome sequence of an OXA-23, OXA-66, ADC-25 and TEM-1D co-producing Acinetobacter baumannii ST195 isolated from a patient with neonatal pneumonia in China.

    abstract：OBJECTIVES:The rapid spread of multidrug-resistant (MDR) Acinetobacter baumannii poses a substantial threat for morbidity and mortality worldwide. In particular, carbapenem-resistant A. baumannii has caused a severe challenge to human health. Here we reported the draft genome sequence of A. baumannii S131434, an OXA-23...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2018.11.008

    authors： Lv W,Zhang X,Hou M,Han D,Li Y,Xiong W

    更新日期：2019-03-01 00:00:00

  • Evaluation of the in vitro antimicrobial activity of selected Saudi scorpion venoms tested against multidrug-resistant micro-organisms.

    abstract：OBJECTIVES:Scorpion venoms are a rich source of bioactive peptides with promising clinical value that may lead to the discovery and development of new drugs. The present study was designed to evaluate the in vitro antimicrobial activities of the venoms extracted from three medically important Saudi scorpions (Androcton...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2017.03.008

    authors： Al-Asmari AK,Alamri MA,Almasoudi AS,Abbasmanthiri R,Mahfoud M

    更新日期：2017-09-01 00:00:00

  • Antimicrobial susceptibility and mechanisms of resistance of Greek Clostridium difficile clinical isolates.

    abstract：OBJECTIVES:This study examined the antimicrobial susceptibility and resistance mechanisms of Clostridium difficile recovered in Greek hospitals during 2012-2015. METHODS:C. difficile isolates (n=88) were collected from clinically-confirmed C. difficile infection from symptomatic patients in 10 Greek hospitals. Minimum...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2018.09.009

    authors： Chatedaki C,Voulgaridi I,Kachrimanidou M,Hrabak J,Papagiannitsis CC,Petinaki E

    更新日期：2019-03-01 00:00:00

  • Draft genome sequence of ST203 vanA Enterococcus faecium strain XH877 from China.

    abstract：:Enterococcus faecium was considered an important nosocomial pathogen that could incur a substantial health burden owing to its high drug resistance and its ability to adapt to the hospital niche. Here we presented the draft genome sequence of multidrug-resistant E. faecium XH877. The draft genome sequence was composed...

    journal_title：Journal of global antimicrobial resistance

    pub_type： 杂志文章

    doi：10.1016/j.jgar.2016.07.004

    authors： Hua X,Sun L,Shi K,Yu Y

    更新日期：2016-12-01 00:00:00