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Draft genome sequence of a multidrug-resistant KPC-2-producing Enterobacter aerogenes isolated from a hospitalised patient in Brazil.

Abstract：

OBJECTIVES:Multidrug-resistant (MDR) Enterobacter aerogenes strains are frequently associated with nosocomial infections and high mortality rates, representing a serious public health problem. The aim of this study was to present the draft genome sequence of a MDR KPC-2-producing E. aerogenes isolated from a perineal swab of a hospitalised patient in Brazil. METHODS:Genomic DNA was sequenced using an Illumina MiSeq platform. De novo genome assembly was carried out using the A5-Miseq pipeline, and whole-genome sequence analysis was performed using tools from the Center for Genomic Epidemiology. RESULTS:The strain harboured resistance genes to β-lactams, aminoglycosides, sulphonamides and trimethoprim in addition to genes encoding multidrug efflux system proteins, a quaternary ammonium transporter and heavy metal efflux system proteins. In addition, the strain harboured genes encoding diverse virulence factors. CONCLUSION:These data might allow a better understanding of the genetic basis of antimicrobial resistance and virulence in E. aerogenes strains.

journal_name

J Glob Antimicrob Resist

journal_title

Journal of global antimicrobial resistance

authors

Moura Q,Fernandes MR,Cerdeira L,Nhambe LF,Ienne S,Souza TA,Lincopan N

doi

10.1016/j.jgar.2017.07.016

subject

Has Abstract

pub_date

2017-09-01 00:00:00

pages

277-278

eissn

2213-7165

issn

2213-7173

pii

S2213-7165(17)30144-3

journal_volume

10

pub_type

杂志文章

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