Case report: A successful combined treatment of severe lupus miliaris disseminatus faciei with oral isotretinoin and methylprednisolone.


:Lupus miliaris disseminates faciei (LMDF) is a rare inflammatory dermatosis characterized by an asymptomatic papular eruption in the central face, of which the etiology and pathogenesis are not clear. There is a lack of standard treatment recommendations, especially for severe cases. Here we report a new case of successful treatment of severe LMDF by the combination therapy of oral isotretinoin and methylprednisolone.


Dermatol Ther


Dermatologic therapy


Yin S,Sun L




Has Abstract


2020-03-01 00:00:00












  • Hypertrophic lichen planus - successful treatment with acitretin.

    abstract::Lichen planus classifies into different subtypes according to morphology and location. Hypertrophic LP (HLP) manifests a great challenge due to persistent itching, the risk to develop into squamous cell carcinoma and therapeutic resistance. We report two clinical cases exemplary for the successful treatment of dramati...

    journal_title:Dermatologic therapy

    pub_type: 杂志文章


    authors: Alamri A,Alsenaid A,Ruzicka T,Wolf R

    更新日期:2016-05-01 00:00:00

  • Visceral leishmaniasis with cutaneous symptoms in a patient treated with infliximab followed by fatal consequences.

    abstract::Leishmaniasis is an infectious disease caused by parasitic flagellates of the genus Leishmania. The authors present a case of 44-year-old man with Crohn's disease treated successfully with infliximab. This case report shows rare visceral leishmaniasis with cutaneous symptoms in an immunocompromised patient. Skin manif...

    journal_title:Dermatologic therapy

    pub_type: 杂志文章


    authors: Juzlova K,Votrubova J,Kacerovska D,Lukas M,Bortlik M,Rohacova H,Nohynkova E,Vojackova N,Fialova J,Hercogova J

    更新日期:2014-05-01 00:00:00

  • Pigmented vulvar lesions.

    abstract::Pigmented lesions represent an enormous range of conditions, from benign to malignant tumors, and from infectious to post-inflammatory. Pigmented lesions are much less easily diagnosed on anogenital skin, and clinicians should have a low threshold for biopsy confirmation of diseases not classic in appearance. ...

    journal_title:Dermatologic therapy

    pub_type: 杂志文章


    authors: Edwards L

    更新日期:2010-09-01 00:00:00

  • Intralesional sclerotherapy for the treatment of acne cysts: A case series.

    abstract::Acne cysts are a common dermatological problem that often leads to scarring and a significant negative impact on patients' psyche. The aim of the study was to evaluate the usefulness of intralesional foam sclerotherapy for the treatment of cystic acne. Patients with cystic acne treated with intralesional foam scleroth...

    journal_title:Dermatologic therapy

    pub_type: 杂志文章


    authors: Bhattacharjee R,Kumar S,Vinay K,Narang T,Dogra S

    更新日期:2020-11-01 00:00:00

  • Stevens-Johnson syndrome and toxic epidermal necrolysis: a review of treatment options.

    abstract::Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe cutaneous reactions that are medication-induced in most instances. While the clinical manifestations of SJS and TEN are well-defined, the optimal treatment for these disorders is not. Case reports have shown benefit with the use of a variet...

    journal_title:Dermatologic therapy

    pub_type: 杂志文章,评审


    authors: Worswick S,Cotliar J

    更新日期:2011-03-01 00:00:00

  • Topical and oral bexarotene.

    abstract::Bexarotene is a retinoid that specifically binds retinoid X receptors and has numerous effects on cellular growth and differentiation. It is approved for the treatment of cutaneous T cell lymphoma both topically and systemically. Adverse effects include hyperlipidemia, central hypothyroidism, and neutropenia with bexa...

    journal_title:Dermatologic therapy

    pub_type: 杂志文章


    authors: Schadt CR

    更新日期:2013-09-01 00:00:00

  • Intravenous antibiotics used in dermatology.

    abstract::It is not common for dermatologists to use intravenous antibiotics in daily practice. However, there are several serious infections that may come to the attention of a dermatologist because of cutaneous signs and symptoms. It is important for dermatologists to be familiar with the presenting symptoms, various stages o...

    journal_title:Dermatologic therapy

    pub_type: 杂志文章,评审


    authors: Sambrano B,Gordon R,Mays R,Lapolla W,Scheinfeld N

    更新日期:2012-01-01 00:00:00

  • Anogenital epidermolytic acanthomas: effective treatment of pruritus with 0.1% tacrolimus ointment.

    abstract::Epidermolytic acanthoma is an uncommon benign tumor with a predilection for the anogenital region, that is characterized histologically by epidermolytic hyperkeratosis. Most reported cases are asymptomatic while some are pruritic. Treatment of this condition is challenging and not well studied. We report a 55-year-old...

    journal_title:Dermatologic therapy

    pub_type: 杂志文章


    authors: Tan GF,Tan ES,Tey HL

    更新日期:2014-03-01 00:00:00

  • Adjusting oral oxybutynin medication for hyperhidrosis to reflect seasonal temperature variations.

    abstract::Most studies of oral oxybutynin (OOx) for the treatment of hyperhidrosis (HH) have assumed a stable treatment protocol, without taking into account adverse effects (AE) or seasonal variations in temperature. The objective is to evaluate adjusting the dose of OOx according to the time of year. Prospective study of pati...

    journal_title:Dermatologic therapy

    pub_type: 杂志文章


    authors: Del Boz J,Millán-Cayetano JF,García-Montero P,García-Harana C,Rivas-Ruiz F,de Troya-Martín M

    更新日期:2018-07-01 00:00:00

  • An analysis of cumulative lifetime solar ultraviolet radiation exposure and the benefits of daily sun protection.

    abstract::Cumulative exposure to ultraviolet radiation (UVR) increases the risk of developing skin cancer, particularly squamous cell carcinoma and basal cell carcinoma. Thus, the need for protection from the sun is widely advocated, but consumers generally associate such protection with the occasional extreme exposure and tend...

    journal_title:Dermatologic therapy

    pub_type: 杂志文章,评审


    authors: Nole G,Johnson AW

    更新日期:2004-01-01 00:00:00

  • Complete resolution of cutaneous larva migrans with topical ivermectin: A case report.

    abstract::Cutaneous larva migrans (CLM; also called creeping eruption) is a cutaneous ectoparasitosis commonly observed in tropical countries. It is characterized by an erythematous, pruritic, and raised lesion with linear or serpiginous distribution, typically localized at the lower extremities. Oral ivermectin represents the ...

    journal_title:Dermatologic therapy

    pub_type: 信件


    authors: Magri F,Chello C,Pranteda G,Pranteda G

    更新日期:2019-05-01 00:00:00

  • Efficacy and tolerability of 20% aluminum sesquichlorohydrate vs 20% aluminum chloride for the treatment of axillary hyperhidrosis: A randomized controlled trial.

    abstract::This study evaluated the efficacy and tolerability of topical aluminum sesquichlorohydrate (AS) when compared to aluminum chloride (AC) as a treatment for primary axillary hyperhidrosis (PAH). Twenty subjects were included in this randomized, controlled, split-side 8-week study. All participants applied 20% AS and 20%...

    journal_title:Dermatologic therapy

    pub_type: 杂志文章


    authors: Thianboonsong T,Kanokrungsee S,Paichitrojjana A,Udompataikul M,Kamanamool N,Rojhirunsakool S

    更新日期:2020-11-01 00:00:00

  • Safety and efficacy of single pass vs multipass emission with 755 alexandrite laser for all-skin-type hair removal: A pilot study.

    abstract::Lasers are considered the most efficient methods for hair reduction. The goal of these devices is to provide long-term effects without adverse reactions. This is a randomized split-body controlled study on body hair removal and pseudofolliculitis (PFC) treatment, comparing the standard single pass (SP) emission with t...

    journal_title:Dermatologic therapy

    pub_type: 杂志文章


    authors: Bonan P,Troiano M,Verdelli A

    更新日期:2020-11-01 00:00:00

  • Soft-tissue augmentation with hyaluronic acid and calcium hydroxyl apatite fillers.

    abstract::Soft-tissue augmentation with hyaluronic acid and calcium hydroxyl apatite are among the most widely used minimally invasive cosmetic treatments for the correction of contour deficiencies and wrinkles of the face without the risk, recovery time, and expense of a major surgery. Training and experience in the art and sc...

    journal_title:Dermatologic therapy

    pub_type: 杂志文章


    authors: Redbord KP,Busso M,Hanke CW

    更新日期:2011-01-01 00:00:00

  • Photodynamic therapy: treatment of choice for actinic cheilitis?

    abstract::The major therapeutic approaches (5-fluorouracil, imiquimod, vermilionectomy, and CO(2) Laser ablation) for actinic cheilitis are aimed at avoiding and preventing a malignant transformation into invasive squamous cell carcinoma via destruction/removal of the damaged epithelium. Recently, photodynamic therapy (PDT) has...

    journal_title:Dermatologic therapy

    pub_type: 杂志文章


    authors: Rossi R,Assad GB,Buggiani G,Lotti T

    更新日期:2008-09-01 00:00:00

  • Juvenile psoriatic arthritis and comorbidities: report of a case associated with enthesitis and celiac disease.

    abstract::The present authors report the case of a 9-year-old boy affected by psoriasis, juvenile psoriatic arthritis, enthesitis, and celiac disease. The signs and symptoms of the different comorbidities appeared at different times in the clinical history, complicating the overall diagnostic and therapeutic procedures. Coopera...

    journal_title:Dermatologic therapy

    pub_type: 杂志文章


    authors: Prignano F,Bonciani D,Bandinelli F,Matucci Cerinic M,Lotti T

    更新日期:2010-03-01 00:00:00

  • Morgellons disease?

    abstract::Morgellons disease, a pattern of dermatologic symptoms very similar, if not identical, to those of delusions of parasitosis, was first described many centuries ago, but has recently been given much attention on the internet and in the mass media. The present authors present a history of Morgellons disease, in addition...

    journal_title:Dermatologic therapy

    pub_type: 杂志文章


    authors: Accordino RE,Engler D,Ginsburg IH,Koo J

    更新日期:2008-01-01 00:00:00

  • Dressings for chronic wounds.

    abstract::Covering wounds, acute and chronic, is one of the most fundamental activities of any medical practitioner. Although wound dressings primarily serve to contain the "good" and keep out the "bad," research has characterized more specifically the sophisticated interaction between the human wound bed and its dressing count...

    journal_title:Dermatologic therapy

    pub_type: 杂志文章,评审


    authors: Powers JG,Morton LM,Phillips TJ

    更新日期:2013-05-01 00:00:00

  • Oral zinc therapy for zinc deficiency-related telogen effluvium.

    abstract::Zinc is crucial for maintaining human body homeostasis and is one of the major components of hormones, signal molecules, and enzymes. Zinc deficiency is caused by insufficient uptake of zinc from food, or caused by malabsorption syndromes, increased gastrointestinal and urinary losses, and administration of various me...

    journal_title:Dermatologic therapy

    pub_type: 杂志文章


    authors: Karashima T,Tsuruta D,Hamada T,Ono F,Ishii N,Abe T,Ohyama B,Nakama T,Dainichi T,Hashimoto T

    更新日期:2012-03-01 00:00:00

  • A pilot comparative study of topical latanoprost and tacrolimus in combination with narrow-band ultraviolet B phototherapy and microneedling for the treatment of nonsegmental vitiligo.

    abstract::Prostaglandins and their analogues are beneficial as topical agents in vitiligo treatment, yet neither of the previous study addressed their comparative efficiency with conventional topical agents used in vitiligo treatment. In this pilot (24 patients) left-right comparative study we addressed efficiency of prostaglan...

    journal_title:Dermatologic therapy

    pub_type: 杂志文章


    authors: Korobko IV,Lomonosov KM

    更新日期:2016-11-01 00:00:00

  • Efficacy of oral retinoids for keratoacanthoma centrifugum marginatum.

    abstract::Keratoacanthoma centrifugum marginatum (KCM) is a rare variant of keratoacanthoma. This condition is difficult to diagnose because of its large size and expansive nature and may be diagnosed as a malignant tumor. There are various treatments such as surgery and oral retinoids; however, limited studies have verified th...

    journal_title:Dermatologic therapy

    pub_type: 杂志文章


    authors: Mizuta H,Takahashi A,Mori T,Namikawa K,Nakano E,Muto Y,Jinnai S,Nakama K,Tsutsui K,Yamazaki N

    更新日期:2020-05-01 00:00:00

  • Oral minocycline in the treatment of vitiligo--a preliminary study.

    abstract::For effective treatment of vitiligo, it is as important to arrest the progression of the disease, as it is to induce repigmentation. Epidermal oxidative stress has been documented in vitiligo patients, and there is much support for a free-radical-mediated damage as an initial pathogenic event in melanocyte degeneratio...

    journal_title:Dermatologic therapy

    pub_type: 临床试验,杂志文章


    authors: Parsad D,Kanwar A

    更新日期:2010-05-01 00:00:00

  • Practical retinoid chemoprophylaxis in solid organ transplant recipients.

    abstract::Solid organ transplant recipients are at a significantly increased risk of developing skin cancer. Both systemic and topical retinoids are useful for chemosuppression of skin cancer in this patient population. These drugs can reduce both the present extent and the future development of premalignant and malignant skin ...

    journal_title:Dermatologic therapy

    pub_type: 杂志文章,评审


    authors: Neuhaus IM,Tope WD

    更新日期:2005-01-01 00:00:00

  • Treatment of chronic venous leg ulcers by platelet gel.

    abstract::Chronic venous leg ulcers (CVLU) are chronic wounds, associated with long-standing venous hypertension, which have a poor prognosis for healing. In the process of wound healing the first step is represented by platelet aggregation and subsequent release of growth factors and other mediators, which play a key role in t...

    journal_title:Dermatologic therapy

    pub_type: 杂志文章


    authors: Ficarelli E,Bernuzzi G,Tognetti E,Bussolati O,Zucchi A,Adorni D,De Panfilis G

    更新日期:2008-07-01 00:00:00

  • Serum soluble CD163 and proinflammatory chemokines may be biomarkers of the onset of adverse events in dabrafenib plus trametinib combination therapy for advanced melanoma.

    abstract::Various adverse events (AEs) have been reported to occur at a high rate in patients treated with dabrafenib plus trametinib (D + T) combination therapy. Among such AEs, the incidence of pyrexia was highest among the series of AEs in patients treated with D + T combination therapy. Although little is known about the me...

    journal_title:Dermatologic therapy

    pub_type: 杂志文章


    authors: Amagai R,Fujimura T,Muto Y,Kambayashi Y,Furudate S,Ohuchi K,Okuma T,Hashimoto A,Aiba S

    更新日期:2020-11-14 00:00:00

  • Omalizumab in children and adolescents with chronic spontaneous urticaria: Case series and review of the literature.

    abstract::The recent EAACI/GA2 LEN/EDF/WAO guidelines recommend omalizumab (anti-IgE) for the management of patients aged ≥12 years with chronic urticaria unresponsive to high-doses second-generation H1 -antihistamines (antiH1 ). However, there is little published information on the success of omalizumab for such a treatment in...

    journal_title:Dermatologic therapy

    pub_type: 杂志文章


    authors: Passanisi S,Arasi S,Caminiti L,Crisafulli G,Salzano G,Pajno GB

    更新日期:2020-07-01 00:00:00

  • Efficacy and safety of risankizumab in psoriasis patients who failed anti-IL-17, anti-12/23 and/or anti IL-23: Preliminary data of a real-life 16-week retrospective study.

    abstract::Up until now, real-life experiences on the efficacy of risankizumab in patients who had previously failed anti-IL17, anti-IL12/23 or anti-IL23 inhibitor are not reported. We carried out a single-center, retrospective study, to evaluate the efficacy, safety and tolerability of patients under risankizumab who previously...

    journal_title:Dermatologic therapy

    pub_type: 杂志文章


    authors: Megna M,Fabbrocini G,Ruggiero A,Cinelli E

    更新日期:2020-11-01 00:00:00

  • Apatinib-induced Grade 3 hand-foot syndrome in advanced lung adenocarcinoma successful treated with thalidomide: A case report.

    abstract::Hand-foot syndrome (HFS) is a specific cutaneous toxicity caused by a variety of antitumor drugs. The most common drugs include capecitabine, pegylated liposomal doxorubicin and fluorouracil (PLD), tyrosine kinase inhibitor. It is a dose-limiting cutaneous toxicity of these drugs. We reported an advanced lung adenocar...

    journal_title:Dermatologic therapy

    pub_type: 杂志文章


    authors: Ren Y,Li T,Du LY,Qiu Y,Wang SB,Lei KJ,Jia YM

    更新日期:2020-03-01 00:00:00

  • Emerging role of nanocarriers based topical delivery of anti-fungal agents in combating growing fungal infections.

    abstract::The incidences of fungal infections have greatly increased over the past few years, particularly in humid and industrialized areas. The severity of such infections ranges from being asymptomatic-mild to potentially life-threatening systemic infections. There are limited classes of drugs that are approved for the treat...

    journal_title:Dermatologic therapy

    pub_type: 杂志文章,评审


    authors: Waghule T,Sankar S,Rapalli VK,Gorantla S,Dubey SK,Chellappan DK,Dua K,Singhvi G

    更新日期:2020-11-01 00:00:00

  • Dermoscopy as a useful tool for evaluating melasma and assessing the response to 1064-nm Q-switched Nd:YAG laser.

    abstract::Melasma is a hard-to-manage disorder with considerable relapsing behavior. Dermoscopy emerged to help in comprehensive evaluation of pigmentary disorders and melasma. The aim of the study was to evaluate the potential role of dermoscopy in assessing melasma and monitoring the efficacy of 1064-nm low-fluence Q-switched...

    journal_title:Dermatologic therapy

    pub_type: 杂志文章


    authors: Abdel Hay R,Mohammed FN,Sayed KS,Abd El Fattah NA,Ibrahim S

    更新日期:2020-07-01 00:00:00