Delayed Auditory Evoked Responses in Autism Spectrum Disorder across the Life Span.

abstract：:Traumatic brain injury (TBI) is predominantly a clinical problem of young persons, resulting in chronic cognitive and behavioral deficits. Specifically, the physiological response to a diffuse biomechanical injury in a maturing brain can clearly alter normal neuroplasticity. To properly evaluate and investigate develo...

journal_title：Developmental neuroscience

authors： Giza CC,Prins ML

更新日期：2006-01-01 00:00:00

abstract：:The long noncoding RNA MSNP1AS (moesin pseudogene 1, antisense) is a functional element that was previously associated with autism spectrum disorder (ASD) with genome-wide significance. Expression of MSNP1AS was increased 12-fold in the cerebral cortex of individuals with ASD and 22-fold in individuals with a genome-w...

journal_title：Developmental neuroscience

authors： DeWitt JJ,Hecht PM,Grepo N,Wilkinson B,Evgrafov OV,Morris KV,Knowles JA,Campbell DB

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Neonatal hypoxic-ischemic (HI) encephalopathy occurs in 1-4 per 1,000 live term births and can cause devastating neurodevelopmental disabilities. Currently, therapeutic hypothermia (TH) is the only treatment with proven efficacy. Since TH is associated with decreased cerebral metabolism and cerebral blood fl...

journal_title：Developmental neuroscience

authors： Buckley EM,Patel SD,Miller BF,Franceschini MA,Vannucci SJ

更新日期：2015-01-01 00:00:00

abstract：:Neuron-specific enolase (NSE) is a unique form of the glycolytic enzyme, enolase, which, in the brain, is strictly localized in differentiated neurons and neuroendocrine cells. In this report evidence is presented that NSE is first seen in the cell bodies of developing chick auditory and vestibular neurons shortly aft...

journal_title：Developmental neuroscience

authors： Whitehead MC,Marangos PJ,Connolly SM,Morest DK

更新日期：1982-01-01 00:00:00

abstract：:Neurite outgrowth is dependent on the presence in neurites of assembled microtubules which consist of polymerized tubulin to which microtubule-associated proteins (MAPs) are bound. This study adds to previous evidence of the similarity between the high molecular weight MAPs, MAP1X, MAP1B and MAP5, and explains the dif...

journal_title：Developmental neuroscience

authors： Harrison L,Cheetham ME,Calvert RA

更新日期：1993-01-01 00:00:00

abstract：:Prenatal stress has been associated with detrimental outcomes of pregnancy, including altered brain development leading to behavioural pathologies. The neurosteroid allopregnanolone has been implicated in mediating some of these adverse outcomes following prenatal stress due to its potent inhibitory and anxiolytic eff...

journal_title：Developmental neuroscience

authors： Bennett GA,Palliser HK,Shaw JC,Walker D,Hirst JJ

更新日期：2015-01-01 00:00:00

abstract：:Adult neuronal ceroid lipofuscinosis (NCL), also called Kufs' disease, is clinically distinct from the other NCLs. It is a rare condition which is difficult to diagnose. More than 50% of the reported cases of Kufs' disease are not adult NCL and correspond very likely to a heterogeneous spectrum of lipidoses. Various c...

journal_title：Developmental neuroscience

authors： Martin JJ

更新日期：1991-01-01 00:00:00

abstract：:Nitric oxide may serve as a retrograde messenger to refine or stabilize synapses in the developing nervous system. Whether this action is dependent upon glutamate and the N-methyl-D-aspartate receptor is not yet established. We have used the patch-cluster system in the intermediate gray layer (IGL) of the rat superior...

journal_title：Developmental neuroscience

authors： Mize RR,Scheiner CA,Salvatore MF,Cork RJ

更新日期：1997-01-01 00:00:00

abstract：:In the era of therapeutic hypothermia, reliable preclinical studies are integral to successfully identify neuroprotective strategies to further improve outcomes of encephalopathy at term. We reviewed preclinical neuroprotection studies reported between January 2014 and June 2016 to assess the use of effective temperat...

journal_title：Developmental neuroscience

authors： Galinsky R,Dean JM,Lear CA,Davidson JO,Dhillon S,Wassink G,Bennet L,Gunn AJ

更新日期：2017-01-01 00:00:00

abstract：:Parallel developmental studies of central nervous system myelin proteins and morphology (postnatal days 15-118; P15-118) confirm qualitative similarities but substantial quantitative differences between homozygous mld mice with Billings-Gagliardi and Wolf's 'USA' versus Matthieu's 'Swiss' genetic backgrounds. The USA ...

journal_title：Developmental neuroscience

authors： Billings-Gagliardi S,Tosic M,Matthieu JM,Kirschner DA,Wolf MK

更新日期：1991-01-01 00:00:00

abstract：:Chick embryo retina neurons in culture extend neurites and form synapses. Seven different culture substrates were compared to determine which culture surface would produce the best neuronal survival and neurite extension. The order of survival of retina neurons during 7 days of culture is salt-precipitated collagen gr...

journal_title：Developmental neuroscience

authors： Thompson JM,Pelto DJ

更新日期：1982-01-01 00:00:00

abstract：:In some cells, the development of voltage-gated channels requires synaptic input, while in others it does not. Here we investigate whether the sodium and potassium currents in the skeletal muscle of zebrafish sofa potato (sop(-/-)) mutants develop normally. Zebrafish sop(-/-) mutants do not express nicotinic acetylcho...

journal_title：Developmental neuroscience

authors： Coutts CA,Cunningham ME,Ali DW

更新日期：2009-01-01 00:00:00

abstract：:We have used whole-cell and single-channel recording techniques to investigate the electrophysiological properties of cultured ovine oligodendrocytes (OLGs). Our studies have led to the following conclusions. (1) Cultured mature OLGs express a variety of voltage-dependent K+ conductances including an outward current t...

journal_title：Developmental neuroscience

authors： Soliven B,Szuchet S,Arnason BG,Nelson DJ

更新日期：1989-01-01 00:00:00

abstract：:Cell polarity is one of the most basic properties of all normal cells and loss of polarity is a hallmark of cancer. While multiple proteins have been implicated in the maintenance of cell polarity, the functionally related neoplastic tumor suppressors Lethal giant larvae (Lgl), Scribble and Disks large comprise a uniq...

journal_title：Developmental neuroscience

authors： Vasioukhin V

更新日期：2006-01-01 00:00:00

abstract：:This study analyzed the role of dopamine D1 and D2 receptors in methylphenidate (MPH) conditioned place preference (CPP) in adolescent male and female rats, in addition to the role of these receptors in the effects of MPH on brain-derived neurotrophic factor (BDNF) in the dorsal striatum and nucleus accumbens. Using a...

journal_title：Developmental neuroscience

authors： Cummins ED,Griffin SB,Duty CM,Peterson DJ,Burgess KC,Brown RW

更新日期：2014-01-01 00:00:00

abstract：:Developmental expression of neutral monoglycosylceramides (MGCs) has been examined in rat brain from embryonic day 15 (E15) to postnatal day 30 (P30) and adulthood. To this point, glucosylceramide (GlcCer) is the only MGC that has been characterized in embryonic brain. Galactosylceramide (GalCer) appears at P1, increa...

journal_title：Developmental neuroscience

authors： Dasgupta S,Everhart MB,Bhat NR,Hogan EL

更新日期：1997-01-01 00:00:00

abstract：:Extracts prepared from embryonic, neonatal and adult rat brain were examined for the presence of oligodendroglial mitogens. Brain-derived mitogenic activities were found in all developmental stages with specific activity increasing during neonatal development. Extracts from postnatal day 7 contained the highest specif...

journal_title：Developmental neuroscience

authors： Saneto RP,de Vellis J

更新日期：1985-01-01 00:00:00

abstract：:Glutamine synthesis, the major pathway of ammonia detoxification, and the intracellular concentration of organic osmolytes in primary astrocytes and F98 glioma cells were investigated with multinuclear magnetic resonance spectroscopy. Acute exposure to ammonia (3 h incubation with NH4Cl) raised the concentration of gl...

journal_title：Developmental neuroscience

authors： Zwingmann C,Brand A,Richter-Landsberg C,Leibfritz D

更新日期：1998-01-01 00:00:00

abstract：:The development of the chick bulbar cardiac ganglia has been studied ultrastructurally from the 3rd day of incubation to hatching. For descriptive purposes, their development has been divided into three phases. The first phase includes migration and aggregation of undifferentiated neuroblasts, stages 21-26 (day 3.5-5)...

journal_title：Developmental neuroscience

authors： Kirby ML,Weidman TA,McKenzie JW

更新日期：1980-01-01 00:00:00

abstract：:Neuronal heterotopia is a malformation of cortical development that is closely associated with epilepsy in humans. Despite emerging interest in the structure and function of the heterotopic cortex, little is known about the membrane properties and synaptic connections of these displaced neurons. We used whole-cell pat...

journal_title：Developmental neuroscience

authors： Smith BN,Dudek FE,Roper SN

更新日期：1999-11-01 00:00:00

abstract：:HIV-1 is able to penetrate the developing human central nervous system and induce damage. Clinical and neuropathological observations demonstrate that (a) the virus is transmitted during the late phase of pregnancy or at the time of delivery; (b) the main infected cells within the brain are macrophages, and (c) the me...

journal_title：Developmental neuroscience

authors： Tardieu M,Janabi N

更新日期：1994-01-01 00:00:00

abstract：:In the socially monogamous prairie vole, we have observed that small changes in early handling, as well as early hormonal manipulations can have long-lasting and sexually dimorphic effects on behavior. These changes may be mediated in part by changes in parental interactions with their young, acting on systems that re...

journal_title：Developmental neuroscience

authors： Carter CS,Boone EM,Pournajafi-Nazarloo H,Bales KL

更新日期：2009-01-01 00:00:00

abstract：:Adrenoleukodystrophy (ALD) is an X-linked recessive disorder that affects mainly the nervous system white matter and the adrenal cortex. It is associated with an abnormal accumulation of saturated very long chain fatty acids and can be diagnosed by demonstrating an excess of these substances in plasma or red cells. Ou...

journal_title：Developmental neuroscience

authors： Moser HW,Moser AB,Naidu S,Bergin A

更新日期：1991-01-01 00:00:00

abstract：:When cells from the cerebellum of late-gestation rats were grown at low density (50-100 cells/mm2) in a three-dimensional culture system, they rapidly expressed morphological and electrophysiological properties of neurons. Growth and differentiation of the population of solitary neurons as a whole was statistically as...

journal_title：Developmental neuroscience

authors： Coates PW,Fermini B,Strahlendorf JC,Strahlendorf HK

更新日期：1992-01-01 00:00:00

abstract：:The distal segments of the crush-injured and permanently transected sciatic nerve provide models to study Schwann cell activity in the presence and absence of Schwann cell-axonal contact, respectively. We examined the quantity and quality of transcript coding for the myelin-associated glycoprotein (MAG) over a 3-week ...

journal_title：Developmental neuroscience

authors： Gupta SK,Poduslo JF,Dunn R,Roder J,Mezei C

更新日期：1990-01-01 00:00:00

abstract：:The kinetics and sodium-dependence of gamma-aminobutyric acid (GABA), hypotaurine and taurine uptake were analyzed in cerebral slices prepared from mice of different postnatal ages. The maximal velocities of transport (V) and the Km constants for the high-affinity uptake all decreased with age, whereas the development...

journal_title：Developmental neuroscience

authors： Oja SS,Kontro P

更新日期：1983-01-01 00:00:00

abstract：:The norepinephrine content of hypothalamus in vehicle-treated control rats gradually increases between days 16 and 45 of life. Norepinephrine contents of the hypothalamus and mesencephalon of the thyroxine-treated (10 microgram/g b.w., s.c., days 8-10) animals also increase between days 16 and 21. Mesencephalic and hy...

journal_title：Developmental neuroscience

authors： Lengvári I,Branch BJ,Taylor AN

更新日期：1980-01-01 00:00:00

abstract：:The fine structure of pituicytes was investigated between 15 days of fetal life and 120 days postnatum. Prior to the penetration of neurosecretory axons into the neural lobe a uniform population of undifferentiated pituicytes is presented. Coincidental with the first appearance of neurosecretory axons in the neural lo...

journal_title：Developmental neuroscience

authors： Dellmann HD,Sikora K

更新日期：1981-01-01 00:00:00

abstract：:The Notch signaling pathway is important at several stages of retinal development including the differentiation of retinal ganglion cells and Muller glia. The downstream effectors of Notch signaling, Hes1 and Hes5, have been shown to be critical in the retina as well. While Notch activity directly regulates Hes1 and H...

journal_title：Developmental neuroscience

authors： Nelson BR,Gumuscu B,Hartman BH,Reh TA

更新日期：2006-01-01 00:00:00

abstract：:Developing neurons synthesize substantial quantities of membrane phospholipids in producing new synapses. We investigated the effects of maternal uridine (as uridine-5'-monophosphate) and docosahexaenoic acid supplementation on pups' brain phospholipids, synaptic proteins and dendritic spine densities. Dams consumed n...

journal_title：Developmental neuroscience

authors： Cansev M,Marzloff G,Sakamoto T,Ulus IH,Wurtman RJ

更新日期：2009-01-01 00:00:00