Uncovering ferroelectric polarization in tetragonal (Bi1/2K1/2)TiO3-(Bi1/2Na1/2)TiO3 single crystals.

abstract：:Ethnic admixtures may interfere with the definition of type 1 diabetes (T1D) risk determinants. The role of HLA, PTPN22, INS-VNTR, and CTLA4 in T1D predisposition was analyzed in Brazilian T1D patients (n = 915), with 81.7% self-reporting as white and 789 controls (65.6% white). The results were corrected for populati...

journal_title：Scientific reports

authors： Gomes KF,Santos AS,Semzezem C,Correia MR,Brito LA,Ruiz MO,Fukui RT,Matioli SR,Passos-Bueno MR,Silva ME

更新日期：2017-03-06 00:00:00

abstract：:Large-scale molecular epidemiologic studies of Plasmodium falciparum parasites have provided insights into parasite biology and transmission, can identify the spread of drug resistance, and are useful in assessing vaccine targets. The polyclonal nature infections in high transmission settings is problematic for tradit...

journal_title：Scientific reports

authors： Levitt B,Obala A,Langdon S,Corcoran D,O'Meara WP,Taylor SM

更新日期：2017-01-24 00:00:00

abstract：:Although TRAIL can directly induce cell death in some cancer cells, it appears that TRAIL resistance exists in many cancers. This study focuses on anti-cancer drugs for TRAIL-resistant head and neck cancer (HNC) to provide further progress toward effective cancer therapy. Results indicate in TRAIL-resistant HNC cells,...

journal_title：Scientific reports

authors： Lee BS,Kim YS,Kim HJ,Kim DH,Won HR,Kim YS,Kim CH

更新日期：2018-08-21 00:00:00

abstract：:Given that the biological processes governing the oncogenesis of pancreatic cancers could present useful therapeutic targets, there is a pressing need to molecularly distinguish between different clinically relevant pancreatic cancer subtypes. To address this challenge, we used targeted proteomics and other molecular ...

journal_title：Scientific reports

authors： Sinkala M,Mulder N,Martin D

更新日期：2020-01-27 00:00:00

abstract：:Circulating miRNAs have attracted attention as serum biomarkers for several diseases. In this study, we aimed to evaluate the diagnostic value of circulating miRNA-21 (miR-21) as a novel biomarker for elderly patients with type 2 cardiorenal syndrome (CRS-2). A total of 157 elderly patients with chronic heart failure ...

journal_title：Scientific reports

authors： Wang Y,Liang Y,Zhao W,Fu G,Li Q,Min X,Guo Y

更新日期：2020-03-17 00:00:00

abstract：:Infection of bone is a severe complication due to the variety of bacteria causing it, their resistance against classical antibiotics, the formation of a biofilm and the difficulty to eradicate it. Antimicrobial peptides (AMPs) are naturally occurring peptides and promising candidates for treatment of joint infections....

journal_title：Scientific reports

authors： Bormann N,Koliszak A,Kasper S,Schoen L,Hilpert K,Volkmer R,Kikhney J,Wildemann B

更新日期：2017-05-04 00:00:00

abstract：:New ionic liquids with multiple Brönsted acid sites were synthesized in ≥98% yield, and their inhibiting properties for the corrosion of carbon steel in 0.5 M HCl solution had been evaluated using electrochemical impedance spectroscopy, potentiodynamic polarization and weight loss method, finally the possible inhibiti...

journal_title：Scientific reports

authors： Cao S,Liu D,Zhang P,Yang L,Yang P,Lu H,Gui J

更新日期：2017-08-18 00:00:00

abstract：:The response of olfactory receptor neurons to odor mixtures is not well understood. Here, using experimental constraints, we investigate the mathematical structure of the odor response space and its consequences. The analysis suggests that the odor response space is 3-dimensional, and predicts that the dose-response c...

journal_title：Scientific reports

authors： Marasco A,De Paris A,Migliore M

更新日期：2016-04-07 00:00:00

abstract：:Deformable elastomeric spheres are evaluated experimentally as they skip multiple times over a lake surface. Some spheres are embedded with small inertial measurement units to measure the acceleration experienced during water surface impact. A model for multiple impact events shows good agreement between measured acce...

journal_title：Scientific reports

authors： Hurd RC,Belden J,Bower AF,Holekamp S,Jandron MA,Truscott TT

更新日期：2019-04-15 00:00:00

abstract：:Although semantic processing has traditionally been associated with brain responses maximal at 350-400 ms, recent studies reported that words of different semantic types elicit topographically distinct brain responses substantially earlier, at 100-200 ms. These earlier responses have, however, been achieved using insu...

journal_title：Scientific reports

authors： Moseley RL,Pulvermüller F,Shtyrov Y

更新日期：2013-01-01 00:00:00

abstract：:The prevalence of chronic kidney disease (CKD), characterized by progressive renal dysfunction with tubulointerstitial fibrosis, is increasing because of societal aging. Uremic toxins, accumulated during renal dysfunction, cause kidney damage, leading to renal deterioration. A recent metabolomic analysis revealed that...

journal_title：Scientific reports

authors： Okada A,Nangaku M,Jao TM,Maekawa H,Ishimono Y,Kawakami T,Inagi R

更新日期：2017-09-11 00:00:00

abstract：:Repeated blood pressure (BP) measurements allow better control of hypertension. Current measurements rely on cuff-based devices. The aim of the present study was to compare BP measurements using a novel cuff-less photoplethysmography-based device to a standard sphygmomanometer device. Males and females were recruited ...

journal_title：Scientific reports

authors： Nachman D,Gepner Y,Goldstein N,Kabakov E,Ishay AB,Littman R,Azmon Y,Jaffe E,Eisenkraft A

更新日期：2020-09-30 00:00:00

abstract：:Dislocations in crystals are linear crystallographic defects, which move in lattice when crystals are plastically deformed. Motion of a partial dislocation may remove or create stacking fault characterized with a partial of a lattice translation vector. Here we report that motion of partial dislocations inside an inte...

journal_title：Scientific reports

authors： Yang B,Zhou YT,Chen D,Ma XL

更新日期：2013-01-01 00:00:00

abstract：:During the infection process, the influenza fusion peptide (FP) inserts into the host membrane, playing a crucial role in the fusion process between the viral and host membranes. In this work we used a combination of simulation and experimental techniques to analyse the molecular details of this process, which are lar...

journal_title：Scientific reports

authors： Lousa D,Pinto AR,Victor BL,Laio A,Veiga AS,Castanho MA,Soares CM

更新日期：2016-06-15 00:00:00

abstract：:Rising global temperatures are proving to be detrimental for the agriculture. Hence, strategies are needed to induce thermotolerance in food crops to sustain the food production. GABA (γ-aminobutyric acid), a non-protein amino acid, can partially protect plants from high-temperature stress. This study hypothesises tha...

journal_title：Scientific reports

authors： Priya M,Sharma L,Kaur R,Bindumadhava H,Nair RM,Siddique KHM,Nayyar H

更新日期：2019-05-24 00:00:00

abstract：:Dogs' attachment towards humans might be the core of their social skillset, yet the origins of their ability to build such a bond are still unclear. Here we show that adult, hand-reared wolves, similarly to dogs, form individualized relationship with their handler. During separation from their handler, wolves, much li...

journal_title：Scientific reports

authors： Lenkei R,Újváry D,Bakos V,Faragó T

更新日期：2020-10-14 00:00:00

abstract：:Thin waveguides such as graded-index lenses and fiber bundles are often used as imaging probes for high-resolution endomicroscopes. However, strong back-reflection from the end surfaces of the probes makes it difficult for them to resolve weak contrast objects, especially in the reflectance-mode imaging. Here we propo...

journal_title：Scientific reports

authors： Yoon C,Kang M,Hong JH,Yang TD,Xing J,Yoo H,Choi Y,Choi W

更新日期：2017-07-26 00:00:00

abstract：:The distribution of attention between competing processing demands can have dramatic real-world consequences, however little is known about how limited attentional resources are distributed during real-world behaviour. Here we employ mobile EEG to characterise the allocation of attention across multiple sensory-cognit...

journal_title：Scientific reports

authors： Ladouce S,Donaldson DI,Dudchenko PA,Ietswaart M

更新日期：2019-11-01 00:00:00

abstract：:HIF-1α, an essential transcription factor under hypoxic condition, is indispensable for chondrocytes during skeletal development but its expression and roles in articular chondrocytes are yet to be revealed. We examined HIF-1α protein expression and the hypoxic condition during mouse osteoarthritis (OA) development us...

journal_title：Scientific reports

authors： Okada K,Mori D,Makii Y,Nakamoto H,Murahashi Y,Yano F,Chang SH,Taniguchi Y,Kobayashi H,Semba H,Takeda N,Piao W,Hanaoka K,Nagano T,Tanaka S,Saito T

更新日期：2020-03-25 00:00:00

abstract：:Parasite death via ion channel activations is the hallmark of anthelmintic and antiparasitic drugs. Glutamate gated chloride channel (GluCl) is a prominent targets for drug selection and design in parasitology. We report several iodine-fluorine based lead activators of GluCl by computational studies and structure-acti...

journal_title：Scientific reports

authors： Rajasekharan SK,Lee JH,Ravichandran V,Kim JC,Park JG,Lee J

更新日期：2019-02-14 00:00:00

abstract：:Previously, Aznar et al., showed that Daple/CCDC88C enables Wnt receptors to transactivate trimeric G-proteins during non-canonical Wnt signaling via a novel G-protein binding and activating (GBA) motif. By doing so, Daple serves two opposing roles; earlier during oncogenesis it suppresses neoplastic transformation an...

journal_title：Scientific reports

authors： Ear J,Dunkel Y,Mittal Y,Lim BBC,Liu L,Holda MK,Nitsche U,Barbazán J,Goel A,Janssen KP,Aznar N,Ghosh P

更新日期：2019-08-20 00:00:00

abstract：:Across multiple taxa, population structure and dynamics depend on effective signalling between individuals. Among mammals, chemical communication is arguably the most important sense, underpinning mate choice, parental care, territoriality and even disease transmission. There is a growing body of evidence that odours ...

journal_title：Scientific reports

authors： Kean EF,Bruford MW,Russo IM,Müller CT,Chadwick EA

更新日期：2017-10-19 00:00:00

abstract：:Voltage gated sodium channels are key players in aberrant pain signaling and sensitization of nociceptors after peripheral nerve injury. The extent to which sodium channel activity after injury contributes to synaptic transmission at the first pain synapse however remains unclear. To investigate the effect of axotomy ...

journal_title：Scientific reports

authors： Vysokov N,McMahon SB,Raouf R

更新日期：2019-09-09 00:00:00

abstract：:Algae-bacteria interaction is one of the main factors underlying the formation of harmful algal blooms (HABs). The aim of this study was to develop a genome-wide high-throughput screening method to identify HAB-influenced specific interactive bacterial metabolites using a comprehensive collection of gene-disrupted E. ...

journal_title：Scientific reports

authors： Heo J,Cho K,Kim U,Cho DH,Ko S,Tran QG,Lee YJ,Ryu CM,Kim HS

更新日期：2020-06-30 00:00:00

abstract：:Electrospun polycaprolactone (PCL) vascular grafts showed good mechanical properties and patency. However, the slow degradation of PCL limited vascular regeneration in the graft. Polydioxanone (PDS) is a biodegradable polymer with high mechanical strength and moderate degradation rate in vivo. In this study, a small-d...

journal_title：Scientific reports

authors： Pan Y,Zhou X,Wei Y,Zhang Q,Wang T,Zhu M,Li W,Huang R,Liu R,Chen J,Fan G,Wang K,Kong D,Zhao Q

更新日期：2017-06-15 00:00:00

abstract：:Bisacylphosphane oxides (BAPOs) are established as photoinitiators for industrial applications. Light irradiation leads to their photolysis, producing radicals. Radical species induce oxidative stress in cells and may cause cell death. Hence, BAPOs may be suitable as photolatent cytotoxic agents, but such applications...

journal_title：Scientific reports

authors： Beil A,Steudel FA,Bräuchle C,Grützmacher H,Möckl L

更新日期：2019-04-12 00:00:00

abstract：:Dysfunction or death of retinal pigment epithelial (RPE) cells is involved in some forms of Retinitis Pigmentosa and in age-related macular degeneration (AMD). Since there is no cure for most patients affected by these diseases, the transplantation of RPE cells derived from human pluripotent stem cells (hPSCs) represe...

journal_title：Scientific reports

authors： Regent F,Morizur L,Lesueur L,Habeler W,Plancheron A,Ben M'Barek K,Monville C

更新日期：2019-07-23 00:00:00

abstract：:Shewanella species are facultative anaerobic bacteria that colonize redox-stratified habitats where O2 and nutrient concentrations fluctuate. The model species Shewanella oneidensis MR-1 possesses genes coding for three terminal oxidases that can perform O2 respiration: a bd-type quinol oxidase and cytochrome c oxidas...

journal_title：Scientific reports

authors： Le Laz S,Kpebe A,Bauzan M,Lignon S,Rousset M,Brugna M

更新日期：2016-01-27 00:00:00

abstract：:Global climate change has resulted in a warmer Arctic, with projections indicating accelerated modifications to permafrost in the near future. The thermal, hydrological, and mechanical physics of permafrost thaw have been hypothesized to couple in a complex fashion but data collection efforts to study these feedbacks ...

journal_title：Scientific reports

authors： Wagner AM,Lindsey NJ,Dou S,Gelvin A,Saari S,Williams C,Ekblaw I,Ulrich C,Borglin S,Morales A,Ajo-Franklin J

更新日期：2018-07-19 00:00:00

abstract：:ADC is a potential post treatment imaging biomarker in colorectal liver metastasis however measurements are affected by respiratory motion. This is compounded by increased statistical uncertainty in ADC measurement with decreasing tumour volume. In this prospective study we applied a retrospective motion correction me...

journal_title：Scientific reports

authors： Pathak R,Tian J,Thacker NA,Morris DM,Ragheb H,Saunders C,Saunders M,Jackson A

更新日期：2019-03-07 00:00:00