A short artificial antimicrobial peptide shows potential to prevent or treat bone infections.

abstract：:Aconiti Lateralis Radix Praeparata (Fuzi) is obtained from processed daughter roots of Aconitum carmichaeli, a toxic plant with a high medical value well known in Chinese medicine. In addition to the known toxic alkaloids (aconitine, mesaconitine, and hypaconitine) and bioactive alkaloids (benzoylaconine, benzoylmesac...

journal_title：Scientific reports

authors： He F,Wang CJ,Xie Y,Cheng CS,Liu ZQ,Liu L,Zhou H

更新日期：2017-10-12 00:00:00

abstract：:Five-component icosahedral quasicrystals with compositions in the range Al68-73Fe11-16Cu10-12Cr1-4Ni1-2 were recently recovered after shocking metallic CuAl5 and (Mg0.75Fe0.25)2SiO4 olivine in a stainless steel 304 chamber, intended to replicate a natural shock that affected the Khatyrka meteorite. The iron in those q...

journal_title：Scientific reports

authors： Oppenheim J,Ma C,Hu J,Bindi L,Steinhardt PJ,Asimow PD

更新日期：2017-11-15 00:00:00

abstract：:Interfacial charge transfer from photoexcited ruthenium-based N3 dye molecules into ZnO thin films received controversial interpretations. To identify the physical origin for the delayed electron transfer in ZnO compared to TiO2, we probe directly the electronic structure at both dye-semiconductor interfaces by applyi...

journal_title：Scientific reports

authors： Borgwardt M,Wilke M,Kampen T,Mähl S,Xiao M,Spiccia L,Lange KM,Kiyan IY,Aziz EF

更新日期：2016-04-13 00:00:00

abstract：:Mouse Tmc1 and Tmc2 are required for sensory transduction in cochlear and vestibular hair cells. Homozygous Tmc1∆/∆ mice are deaf, Tmc2∆/∆ mice have normal hearing, and double homozygous Tmc1∆/∆; Tmc2∆/∆ mice have deafness and profound vestibular dysfunction. These phenotypes are consistent with their different spatio...

journal_title：Scientific reports

authors： Nakanishi H,Kurima K,Pan B,Wangemann P,Fitzgerald TS,Géléoc GS,Holt JR,Griffith AJ

更新日期：2018-08-14 00:00:00

abstract：:Uniaxial-stress experiments have been performed for the 3287- and 2445-cm-1 local vibrational modes assigned to the positive charge state of interstitial hydrogen [Formula: see text] and deuterium [Formula: see text], respectively, occurring in mono-crystalline rutile TiO2. The onset of the defect alignment under the ...

journal_title：Scientific reports

authors： Hupfer AJ,Monakhov EV,Svensson BG,Chaplygin I,Lavrov EV

更新日期：2017-12-06 00:00:00

abstract：:Malaria is a fatal disease that displays a spectrum of symptoms and severity, which are determined by complex host-parasite interactions. It has been difficult to study the effects of parasite strains on disease severity in human infections, but the mechanisms leading to specific disease phenotypes can be investigated...

journal_title：Scientific reports

authors： Lacerda-Queiroz N,Riteau N,Eastman RT,Bock KW,Orandle MS,Moore IN,Sher A,Long CA,Jankovic D,Su XZ

更新日期：2017-09-05 00:00:00

abstract：:We herein report the construction of a novel azo-linked conjugated microporous polymers (Ag@AzoTPE-CMP), which possesses permanent porous structure and Ag+ loading up of 7.62% in the skeleton as effective sorption sites. Ag@AzoTPE-CMP shows considerable adsorption capacity of iodine of 202 wt% in iodine vapor at 350 K...

journal_title：Scientific reports

authors： Liu M,Yao C,Liu C,Xu Y

更新日期：2018-09-19 00:00:00

abstract：:The opportunistic pathogen Staphylococcus aureus is responsible for causing infections related to indwelling medical devices, where this pathogen is able to attach and form biofilms. The intrinsic properties given by the self-produced extracellular biofilm matrix confer high resistance to antibiotics, triggering infec...

journal_title：Scientific reports

authors： Matilla-Cuenca L,Gil C,Cuesta S,Rapún-Araiz B,Žiemytė M,Mira A,Lasa I,Valle J

更新日期：2020-11-03 00:00:00

abstract：:Abdominal aortic aneurysm (AAA) is a leading cause of sudden death in aged people. Activation of ubiquitin proteasome system (UPS) plays a critical role in the protein quality control and various diseases. However, the functional role of UPS in AAA formation remains unclear. In this study, we found that the proteasome...

journal_title：Scientific reports

authors： Ren H,Li F,Tian C,Nie H,Wang L,Li HH,Zheng Y

更新日期：2015-10-28 00:00:00

abstract：:Brood is a very valuable part of an ant colony and behaviours increasing its number with minimum investment is expected to be favoured by natural selection. Brood theft has been well documented in ants belonging to the subfamilies Myrmicinae and Formicinae. In this study we report opportunistic brood theft in the cont...

journal_title：Scientific reports

authors： Paul B,Paul M,Annagiri S

更新日期：2016-10-31 00:00:00

abstract：:Although 3,5,3'-triiodothyronine (T3) is considered to be the primary bioactive thyroid hormone (TH) due to its high affinity for TH nuclear receptors (TRs), new data suggest that 3,5-diiodothyronine (T2) can also regulate transcriptional networks. To determine the functional relevance of these bioactive THs, RNA-seq ...

journal_title：Scientific reports

authors： Olvera A,Martyniuk CJ,Buisine N,Jiménez-Jacinto V,Sanchez-Flores A,Sachs LM,Orozco A

更新日期：2017-11-08 00:00:00

abstract：:Knowing which geodynamic regimes characterised the early Earth is a fundamental question. This implies to determine when and how modern plate tectonics began. Today, the tectonic regime is dominated by mobile-lid tectonics including deep and cold subduction. However, in the early Earth (4.5 to 2 Ga) stagnant-lid tecto...

journal_title：Scientific reports

authors： François C,Debaille V,Paquette JL,Baudet D,Javaux EJ

更新日期：2018-10-18 00:00:00

abstract：:The analysis of structural and functional neuroimaging data using graph theory has increasingly become a popular approach for visualising and understanding anatomical and functional relationships between different cerebral areas. In this work we applied a network-based approach for brain PET studies using population-b...

journal_title：Scientific reports

authors： Veronese M,Moro L,Arcolin M,Dipasquale O,Rizzo G,Expert P,Khan W,Fisher PM,Svarer C,Bertoldo A,Howes O,Turkheimer FE

更新日期：2019-02-21 00:00:00

abstract：:Accumulating evidences have suggested the potential association between Int7G24A (rs334354) polymorphism and cancer risk. However, results from epidemiological studies are controversial. We thus conducted this meta-analysis to clarify the association. Relevant studies were identified on electronic databases according ...

journal_title：Scientific reports

authors： Wu W,Tong Y,Wei X,Zhao Q,Pan X,Yu G,Lu Q

更新日期：2015-06-15 00:00:00

abstract：:The mechanisms underlying the discovery of abstract rules like those found in natural language may be evolutionarily tuned to speech, according to previous research. When infants hear speech sounds, they can learn rules that govern their combination, but when they hear non-speech sounds such as sine-wave tones, they f...

journal_title：Scientific reports

authors： Ferguson B,Lew-Williams C

更新日期：2016-05-06 00:00:00

abstract：:The mosquito, Aedes baisasi, which inhabits brackish mangrove swamps, is known to feed on fish. However, its host assemblage has not been investigated at the species level. We amplified and sequenced the cytochrome oxidase subunit I barcoding regions as well as some other regions from blood-fed females to identify hos...

journal_title：Scientific reports

authors： Miyake T,Aihara N,Maeda K,Shinzato C,Koyanagi R,Kobayashi H,Yamahira K

更新日期：2019-03-08 00:00:00

abstract：:Whole genome sequencing (WGS) can elucidate Mycobacterium tuberculosis (Mtb) transmission patterns but more data is needed to guide its use in high-burden settings. In a household-based TB transmissibility study in Peru, we identified a large MIRU-VNTR Mtb cluster (148 isolates) with a range of resistance phenotypes, ...

journal_title：Scientific reports

authors： Dixit A,Freschi L,Vargas R,Calderon R,Sacchettini J,Drobniewski F,Galea JT,Contreras C,Yataco R,Zhang Z,Lecca L,Kolokotronis SO,Mathema B,Farhat MR

更新日期：2019-04-03 00:00:00

abstract：:Bacteriophage T7 is an intracellular parasite that recognizes its host via its tail and tail fiber proteins, known as receptor-binding proteins (RBPs). The RBPs attach to specific lipopolysaccharide (LPS) features on the host. Various studies have shown expansion of the phage's host range via mutations in the genes en...

journal_title：Scientific reports

authors： Holtzman T,Globus R,Molshanski-Mor S,Ben-Shem A,Yosef I,Qimron U

更新日期：2020-01-15 00:00:00

abstract：:The transparency of animals is an important biological feature. Ascidian eggs have various degrees of transparency, but this characteristic has not yet been measured quantitatively and comprehensively. In this study, we established a method for evaluating the transparency of eggs to first characterize the transparency...

journal_title：Scientific reports

authors： Shito TT,Hasegawa N,Oka K,Hotta K

更新日期：2020-11-30 00:00:00

abstract：:The concentration of CO2 in many aquatic systems is variable, often lower than the KM of the primary carboxylating enzyme Rubisco, and in order to photosynthesize efficiently, many algae operate a facultative CO2 concentrating mechanism (CCM). Here we measured the responses of a marine diatom, Thalassiosira pseudonana...

journal_title：Scientific reports

authors： Clement R,Lignon S,Mansuelle P,Jensen E,Pophillat M,Lebrun R,Denis Y,Puppo C,Maberly SC,Gontero B

更新日期：2017-02-09 00:00:00

abstract：:Fusarium wilt is one of the major biotic stresses reducing chickpea productivity. The use of wilt-resistant cultivars is the most appropriate means to combat the disease and secure productivity. As a step towards understanding the molecular basis of wilt resistance in chickpea, we investigated the transcriptomes of wi...

journal_title：Scientific reports

authors： Upasani ML,Limaye BM,Gurjar GS,Kasibhatla SM,Joshi RR,Kadoo NY,Gupta VS

更新日期：2017-08-10 00:00:00

abstract：:In this paper, we demonstrate a novel dual-pump approach to generate robust optical frequency comb with varying free spectral range (FSR) spacing in a CMOS-compatible high-Q micro-ring resonator (MRR). The frequency spacing of the comb can be tuned by an integer number FSR of the MRR freely in our dual-pump scheme. Th...

journal_title：Scientific reports

authors： Wang W,Chu ST,Little BE,Pasquazi A,Wang Y,Wang L,Zhang W,Wang L,Hu X,Wang G,Hu H,Su Y,Li F,Liu Y,Zhao W

更新日期：2016-06-24 00:00:00

abstract：:During symbiosis, organisms use a range of metabolic and protein-based signals to communicate. Of these protein signals, one class is defined as 'effectors', i.e., small secreted proteins (SSPs) that cause phenotypical and physiological changes in another organism. To date, protein-based effectors have been described ...

journal_title：Scientific reports

authors： Plett JM,Yin H,Mewalal R,Hu R,Li T,Ranjan P,Jawdy S,De Paoli HC,Butler G,Burch-Smith TM,Guo HB,Ju Chen C,Kohler A,Anderson IC,Labbé JL,Martin F,Tuskan GA,Yang X

更新日期：2017-03-23 00:00:00

abstract：:We characterized the microstructural response of the myocardium to cardiovascular disease using diffusion tensor imaging (DTI) and performed histological validation by intact, un-sectioned, three-dimensional (3D) histology using a tissue-clearing technique. The approach was validated in normal (n = 7) and ischemic (n ...

journal_title：Scientific reports

authors： Lee SE,Nguyen C,Yoon J,Chang HJ,Kim S,Kim CH,Li D

更新日期：2018-04-27 00:00:00

abstract：:The impact of environment on individuals is particularly critical. In evolutionary games, adopting the strategy of the neighbor who performs better is nontrivial for the survival and maintenance of cooperation, in that such an action may help the agents to obtain higher benefit and more obvious evolutionary advantages...

journal_title：Scientific reports

authors： Wu Y,Zhang S,Zhang Z

更新日期：2018-10-23 00:00:00

abstract：:Biomarkers reflecting the extent of Mycobacterium tuberculosis-induced pathology and normalization during anti-tuberculosis treatment (ATT) would considerably facilitate trials of new treatment regimens and the identification of patients with treatment failure. Therefore, in a cohort of 99 Indian children with intrath...

journal_title：Scientific reports

authors： Jenum S,Bakken R,Dhanasekaran S,Mukherjee A,Lodha R,Singh S,Singh V,Haks MC,Ottenhoff TH,Kabra SK,Doherty TM,Ritz C,Grewal HM

更新日期：2016-12-12 00:00:00

abstract：:Lipopolysaccharide (LPS) is a major component of the outer wall of gram negative bacteria. In high doses LPS contributes to the inflammation in gram negative sepsis, and in low doses contributes to the low grade inflammation characteristic of the metabolic syndrome. We wanted to assess the role of beta2-glycoprotein I...

journal_title：Scientific reports

authors： Zhou S,Chen G,Qi M,El-Assaad F,Wang Y,Dong S,Chen L,Yu D,Weaver JC,Beretov J,Krilis SA,Giannakopoulos B

更新日期：2016-09-27 00:00:00

abstract：:This study aimed to examine the effect of transcutaneous electrical nerve stimulation (TENS) on stair climbing capacity in individuals with pre-radiographic to mild knee osteoarthritis (OA). This is a secondary analysis of data from a single, participant-blinded, randomized controlled trial with a pre-post design. Par...

journal_title：Scientific reports

authors： Iijima H,Eguchi R,Shimoura K,Yamada K,Aoyama T,Takahashi M

更新日期：2020-04-29 00:00:00

abstract：:Lipidised analgesic peptide prodrugs self-assemble into peptide nanofibers; with the nanofiber morphology protecting the peptide from plasma degradation and improving therapeutic efficacy. Extending this learning, we hypothesised that a self-assembling lipidized peptide arginine vasopressin (AVP) receptor agonist, tha...

journal_title：Scientific reports

authors： Patel S,Volpe AB,Awwad S,Schätzlein AG,Haider S,Liu B,Uchegbu IF

更新日期：2020-04-29 00:00:00

abstract：:Lack of standardization and unblinding threaten the research of mechanisms involved in expectancy effects on pain. We evaluated a computer-controlled virtual experimenter (VEx) to avoid these issues. Fifty-four subjects underwent a baseline-retest heat pain protocol. Between sessions, they received an expectancy manip...

journal_title：Scientific reports

authors： Horing B,Beadle SC,Inks Z,Robb A,Muth ER,Babu SV

更新日期：2020-11-23 00:00:00