The influence of population stratification on genetic markers associated with type 1 diabetes.

abstract：:Posttraumatic growth (PTG) is defined as positive psychological change in the wake of highly challenging circumstances. Healthcare workers in particular are more vulnerable to stressors and trauma than the general population. The current study examined the use and effectiveness of a novel positive psychological interv...

journal_title：Scientific reports

authors： Xu X,Hu ML,Song Y,Lu ZX,Chen YQ,Wu DX,Xiao T

更新日期：2016-12-20 00:00:00

abstract：:Saliva has immense potential as a diagnostic fluid for identification and monitoring of several systemic diseases. Composition of the microbiome and inflammation has been associated and reflective of oral and overall health. In addition, the relative ease of collection of saliva further strengthens large-scale diagnos...

journal_title：Scientific reports

authors： Sarkar A,Kuehl MN,Alman AC,Burkhardt BR

更新日期：2021-01-29 00:00:00

abstract：:Sweet potato is an important food and bio-energy crop, and investigating the mechanisms underlying salt tolerance will provide information for salt-tolerant breeding of this crop. Here, the root transcriptomes of the salt-sensitive variety Lizixiang and the salt-tolerant line ND98 were compared to identify the genes a...

journal_title：Scientific reports

authors： Zhang H,Zhang Q,Zhai H,Li Y,Wang X,Liu Q,He S

更新日期：2017-01-13 00:00:00

abstract：:An increased breast cancer risk during adulthood has been linked to estrogen exposure during fetal life. However, the impossibility of removing estrogens from the feto-maternal unit has hindered the testing of estrogen's direct effect on mammary gland organogenesis. To overcome this limitation, we developed an ex vivo...

journal_title：Scientific reports

authors： Speroni L,Voutilainen M,Mikkola ML,Klager SA,Schaeberle CM,Sonnenschein C,Soto AM

更新日期：2017-01-19 00:00:00

abstract：:Very recently, we postulated that the incorporation of citral into nanostructured lipid carrier (NLC-Citral) improves solubility and delivery of the citral without toxic effects in vivo. Thus, the objective of this study is to evaluate anti-cancer effects of NLC-Citral in MDA MB-231 cells in vitro through the Annexin ...

journal_title：Scientific reports

authors： Nordin N,Yeap SK,Rahman HS,Zamberi NR,Abu N,Mohamad NE,How CW,Masarudin MJ,Abdullah R,Alitheen NB

更新日期：2019-02-07 00:00:00

abstract：:It is rigorously proved that ideal memcapacitors and meminductors are not passive or cyclo-passive devices. Equivalently, this implies that there exist excitation profiles that allow to extract more energy from the device than it is supplied with; so that their energy conversion efficiency exceeds 100%. This means tha...

journal_title：Scientific reports

authors： Jeltsema D,van der Schaft A

更新日期：2020-10-07 00:00:00

abstract：:Viruses induce double-stranded RNA (dsRNA) in the host cells. The mammalian system has developed dsRNA-dependent recognition receptors such as RLRs that recognize the long stretches of dsRNA as PAMPs to activate interferon-mediated antiviral pathways and apoptosis in severe infection. Here we report an efficient antiv...

journal_title：Scientific reports

authors： Wang W,Wang WH,Azadzoi KM,Su N,Dai P,Sun J,Wang Q,Liang P,Zhang W,Lei X,Yan Z,Yang JH

更新日期：2016-03-03 00:00:00

abstract：:Breast cancer is the most common cancer in women. However, it remains unproven whether psychological factors have an influence on breast cancer incidence. In our earlier study, subjects possessing two personality traits, decisiveness and "ikigai" (a Japanese word meaning something that makes one's life worth living), ...

journal_title：Scientific reports

authors： Sawada T,Nishiyama T,Kikuchi N,Wang C,Lin Y,Mori M,Tanno K,Tamakoshi A,Kikuchi S

更新日期：2016-09-02 00:00:00

abstract：:The present study tested whether the LPS/TLR4 signal pathway in endometrial stromal cells is essential for the pathogenesis of adenomyosis. We tested the expression of TLR4, MD2 in the endometrium without adenomyosis (CE), the eutopic endometrium with adenomyosis (EuE) and the ectopic endometrium with adenomyosis (EE)...

journal_title：Scientific reports

authors： Guo J,Chen L,Luo N,Li C,Chen R,Qu X,Liu M,Kang L,Cheng Z

更新日期：2016-02-22 00:00:00

abstract：:Noise-induced hearing loss (NIHL) is a common health concern with significant social, psychological, and cognitive implications. Moderate levels of acoustic overstimulation associated with tinnitus and impaired speech perception cause cochlear synaptopathy, characterized physiologically by reduction in wave I of the s...

journal_title：Scientific reports

authors： Rouse SL,Matthews IR,Li J,Sherr EH,Chan DK

更新日期：2020-10-22 00:00:00

abstract：:Reactive Intermediate Deaminase (Rid) protein superfamily includes eight families among which the RidA is conserved in all domains of life. RidA proteins accelerate the deamination of the reactive 2-aminoacrylate (2AA), an enamine produced by some pyridoxal phosphate (PLP)-dependent enzymes. 2AA accumulation inhibits ...

journal_title：Scientific reports

authors： Digiovanni S,Visentin C,Degani G,Barbiroli A,Chiara M,Regazzoni L,Di Pisa F,Borchert AJ,Downs DM,Ricagno S,Vanoni MA,Popolo L

更新日期：2020-06-23 00:00:00

abstract：:Xenotransplantation of human cancers into immunodeficient mice is a very useful approach for studying human tumor biology. However, the occasional occurrence of lymphomagenesis in some mice can spoil the model and must be investigated in detail. We found that a high percentage (32.5%, 26/80) of cancer patient-derived ...

journal_title：Scientific reports

authors： Zhang L,Liu Y,Wang X,Tang Z,Li S,Hu Y,Zong X,Wu X,Bu Z,Wu A,Li Z,Li Z,Huang X,Jia L,Kang Q,Liu Y,Sutton D,Wang L,Luo L,Ji J

更新日期：2015-03-30 00:00:00

abstract：:This corrects the article DOI: 10.1038/srep45235. ...

journal_title：Scientific reports

authors： Wu J,Hu S,Chen Y,Li Z,Zhang J,Yuan H,Shi Q,Shao N,Ying X

更新日期：2017-12-22 00:00:00

abstract：:Carrier drift mobility is an important physical constant in the charge transport process of organic solar cells (OSCs). Although time-of-flight and space-charge-limited current techniques have been frequently utilized for mobility measurements, the validity of a new method using modulation photocurrent spectroscopy is...

journal_title：Scientific reports

authors： Nojima H,Kobayashi T,Nagase T,Naito H

更新日期：2019-12-30 00:00:00

abstract：:Many basic properties of the T-cell receptor (TCR) repertoire require clarification, and the changes occurring in the TCR repertoire during carcinogenesis, especially during precancerous stages, remain unclear. This study used deep sequencing analyses to examine 41 gastric tissue samples at different pathological stag...

journal_title：Scientific reports

authors： Kuang M,Cheng J,Zhang C,Feng L,Xu X,Zhang Y,Zu M,Cui J,Yu H,Zhang K,Yang A,Cheng S

更新日期：2017-08-10 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...

journal_title：Scientific reports

authors： Lin RT,Lin CK,Christiani DC,Kawachi I,Cheng Y,Verguet S,Jong S

更新日期：2018-03-12 00:00:00

abstract：:LMNA gene encodes lamins A and C, two major components of the nuclear lamina, a network of intermediate filaments underlying the inner nuclear membrane. Most of LMNA mutations are associated with cardiac and/or skeletal muscles defects. Muscle laminopathies include Emery-Dreifuss Muscular Dystrophy, Limb-Girdle Muscul...

journal_title：Scientific reports

authors： Janin A,Bauer D,Ratti F,Valla C,Bertrand A,Christin E,Chopin E,Streichenberger N,Bonne G,Gache V,Cohen T,Méjat A

更新日期：2018-04-04 00:00:00

abstract：:Pitch is a complex hearing phenomenon that results from elicited and self-generated cochlear vibrations. Read-off vibrational information is relayed higher up the auditory pathway, where it is then condensed into pitch sensation. How this can adequately be described in terms of physics has largely remained an open que...

journal_title：Scientific reports

authors： Martignoli S,Gomez F,Stoop R

更新日期：2013-01-01 00:00:00

abstract：:Oscillatory media can exhibit the coexistence of synchronized and desynchronized regions, so-called chimera states, for uniform parameters and symmetrical coupling. In a phase-balanced chimera state, where the totals of synchronized and desynchronized regions, respectively, are of the same size, the symmetry of the sy...

journal_title：Scientific reports

authors： Haugland SW,Schmidt L,Krischer K

更新日期：2015-04-30 00:00:00

abstract：:Effective population size reflects the history of population growth, contraction, and structuring. When the effect of structuring is negligible, the inferred trajectory of the effective population size can be informative about the key events in the history of a population. We used the IBDNe and DoRIS approaches, which...

journal_title：Scientific reports

authors： Yunusbaev U,Ionusbaev A,Han G,Kwon HW

更新日期：2020-06-16 00:00:00

abstract：:Human CD4+FoxP3+T-cells are heterogeneous in function and include not only suppressive cells (Tregs), but also effector cells that transiently express FoxP3 upon activation. Previous studies in Granulomatosis with Polyangiitis (GPA-)patients have demonstrated an increase in FoxP3+T-cells with impaired suppressive capa...

journal_title：Scientific reports

authors： Reijnders TDY,Stegeman CA,Huitema MG,Rutgers A,Heeringa P,Abdulahad WH

更新日期：2019-06-04 00:00:00

abstract：:Developing rationally controlled bottom-up device fabrication processes is essential for the achievement of high performance optimal devices. We report a controlled, seedless and site-selective hydrothermal technique to fabricate high-performance nanostructured ZnO UV-detectors directly on-chip. We demonstrate that by...

journal_title：Scientific reports

authors： Alenezi MR,Henley SJ,Silva SR

更新日期：2015-02-17 00:00:00

abstract：:The formation and motion features of self interstitial atom (SIA) clusters in tungsten are studied by molecular dynamics (MD) simulations. The static calculations show that the SIA clusters are stable with binding energy over 2 eV. The SIA clusters exhibit a fast one dimensional (1D) motion along 〈111〉. Through analys...

journal_title：Scientific reports

authors： Zhou WH,Zhang CG,Li YG,Zeng Z

更新日期：2014-05-28 00:00:00

abstract：:Infection after renal transplantation remains a major cause of morbidity and death, especially infection from the extensively drug-resistant bacteria, A. baumannii. A total of fourteen A. baumannii isolates were isolated from the donors' preserved fluid from DCD (donation after cardiac death) renal transplantation and...

journal_title：Scientific reports

authors： Jiang H,Cao L,Qu L,Qu T,Liu G,Wang R,Li B,Wang Y,Ying C,Chen M,Lu Y,Feng S,Xiao Y,Wang J,Wu J,Chen J

更新日期：2017-05-16 00:00:00

abstract：:Defects of vitamin B6 metabolism are responsible for severe neurological disorders, such as pyridoxamine 5'-phosphate oxidase deficiency (PNPOD; OMIM: 610090), an autosomal recessive inborn error of metabolism that usually manifests with neonatal-onset severe seizures and subsequent encephalopathy. At present, 27 path...

journal_title：Scientific reports

authors： Barile A,Nogués I,di Salvo ML,Bunik V,Contestabile R,Tramonti A

更新日期：2020-08-12 00:00:00

abstract：:Solar thermal energy conversion has attracted substantial renewed interest due to its applications in industrial heating, air conditioning, and electricity generation. Achieving stagnation temperatures exceeding 200 °C, pertinent to these technologies, with unconcentrated sunlight requires spectrally selective absorbe...

journal_title：Scientific reports

authors： Thomas NH,Chen Z,Fan S,Minnich AJ

更新日期：2017-07-13 00:00:00

abstract：:Identification of AD (Alzheimer's disease)-related genes obtained from blood samples is crucial for early AD diagnosis. We used three public datasets, ADNI, AddNeuroMed1 (ANM1), and ANM2, for this study. Five feature selection methods and five classifiers were used to curate AD-related genes and discriminate AD patien...

journal_title：Scientific reports

authors： Lee T,Lee H

更新日期：2020-02-26 00:00:00

abstract：:To report the efficacy and safety of large diameter scleral lenses and determine their suitability in Asian subjects with intractable ocular surface diseases. This prospective study enrolled intractable ocular surface diseases subjects with uncorrected visual acuity > counting finger but ≥ 0.3 logMAR and best-correcte...

journal_title：Scientific reports

authors： Moon J,Lee SM,Hyon JY,Kim MK,Oh JY,Choi HJ

更新日期：2021-01-27 00:00:00

abstract：:The new π-extended redox-active ligand with both TTF and triazole units, 6-(4,5-bis(propylthio)-1,3-dithiol-2-ylidene)-1H-[1,3]dithiolo[4',5':4,5]benzo [1,2-d] [1-3]triazole, has been successfully prepared. Based on the versatile ligand and Cu(tta)2 precursors (tta(-) = 4,4,4-trifluoro-1-(thiophen-2-yl)butane-1,3-dion...

journal_title：Scientific reports

authors： Cui L,Geng YF,Leong CF,Ma Q,D'Alessandro DM,Deng K,Zeng QD,Zuo JL

更新日期：2016-05-06 00:00:00

abstract：:We investigated the extent to which pre-pregnancy obesity mediates the association between maternal place of birth and severe pre-eclampsia in the PreCARE cohort of pregnant women in Paris (n = 9,579). Adjusted path analysis logistic regression models were used to assess the role of pre-pregnancy obesity as a mediator...

journal_title：Scientific reports

authors： Siddiqui A,Deneux-Tharaux C,Luton D,Schmitz T,Mandelbrot L,Estellat C,Howell EA,Khoshnood B,Bertille N,Azria E

更新日期：2020-03-23 00:00:00