Altered microRNA and target gene expression related to Tetralogy of Fallot.

abstract：:The lateral motion of a magnetic skyrmion, arising because of the skyrmion Hall effect, imposes a number of restrictions on the use of this spin state in the racetrack memory. A skyrmionium is a more promising spin texture for memory applications, since it has zero total topological charge and propagates strictly alon...

journal_title：Scientific reports

authors： Kolesnikov AG,Stebliy ME,Samardak AS,Ognev AV

更新日期：2018-11-16 00:00:00

abstract：:The evolution of bone tissue quantity and quality in contact with the surface of orthopedic and dental implants is a strong determinant of the surgical outcome but remains difficult to be assessed quantitatively. The aim of this study was to investigate the performance of a quantitative ultrasound (QUS) method to meas...

journal_title：Scientific reports

authors： Fraulob M,Vayron R,Le Cann S,Lecuelle B,Hériveaux Y,Albini Lomami H,Flouzat Lachaniette CH,Haïat G

更新日期：2020-12-15 00:00:00

abstract：:Controlled surface wettability for oil has been intensively studied to remove industrial oil waste or oil spill pollution from seas or rivers. In particular, external stimuli-induced special wetting materials, such as photo-responsive TiO2, have attracted considerable attention for oil-water separation. In this study,...

journal_title：Scientific reports

authors： Kim DH,Jung MC,Cho SH,Kim SH,Kim HY,Lee HJ,Oh KH,Moon MW

更新日期：2015-08-11 00:00:00

abstract：:There are three sex ratio strategies (SRS) in nature-male-biased sex ratio, female-biased sex ratio and, equal sex ratio. It was R. A. Fisher who first explained why most species in nature display a sex ratio of ½. Consequent SRS theories such as Hamilton's local mate competition (LMC) and Clark's local resource compe...

journal_title：Scientific reports

authors： Wang Y,Wang R,Li Y,Sam Ma Z

更新日期：2016-12-23 00:00:00

abstract：:Hematopoietic stem cells (HSCs) maintain the entire blood system throughout life and are utilized in therapeutic approaches for blood diseases. Prospective isolation of highly purified HSCs is crucial to understand the molecular mechanisms underlying regulation of HSCs. The zebrafish is an elegant genetic model for th...

journal_title：Scientific reports

authors： Kobayashi I,Kondo M,Yamamori S,Kobayashi-Sun J,Taniguchi M,Kanemaru K,Katakura F,Traver D

更新日期：2019-10-02 00:00:00

abstract：:PC4, a well-known general transcription cofactor, has multiple functions in transcription and DNA repair. Residue W89, is engaged in stacking interactions with DNA in PC4, but substituted by tyrosine in some PC4 orthologous proteins. In order to understand the consequences and reveal the molecular details of this subs...

journal_title：Scientific reports

authors： Huang J,Zhao Y,Liu H,Huang D,Cheng X,Zhao W,Taylor IA,Liu J,Peng YL

更新日期：2015-03-05 00:00:00

abstract：:Vitamin D may reduce mortality from prostate cancer (PC). We examined the associations of post-treatment plasma 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D concentrations with PC mortality. Participants were PC cases from the New South Wales Prostate Cancer Care. All contactable and consenting participants, at 4.9...

journal_title：Scientific reports

authors： Nair-Shalliker V,Bang A,Egger S,Clements M,Gardiner RA,Kricker A,Seibel MJ,Chambers SK,Kimlin MG,Armstrong BK,Smith DP

更新日期：2020-05-08 00:00:00

abstract：:Human immunodeficiency virus type 1 (HIV-1) infection promotes a generalized activation of host responses that involves not only CD4 T cells, but also cells of the microenvironment, which are not directly infected, such as endothelial cells. The mechanisms triggering HIV-1-associated vascular alterations remain poorly...

journal_title：Scientific reports

authors： Balducci E,Leroyer AS,Lacroix R,Robert S,Todorova D,Simoncini S,Lyonnet L,Chareyre C,Zaegel-Faucher O,Micallef J,Poizot-Martin I,Roll P,Dignat-George F

更新日期：2019-07-16 00:00:00

abstract：:The effects of quercetin liposomes (Q-PEGL) on streptozotocin (STZ)-induced diabetic nephropathy (DN) was investigated in rats. Male Sprague Dawley rats were used to establish a STZ induced DN model. DN rats randomly received one of the following treatments for 8 weeks: blank treatment (DN), free quercetin (Que), pegy...

journal_title：Scientific reports

authors： Tang L,Li K,Zhang Y,Li H,Li A,Xu Y,Wei B

更新日期：2020-02-12 00:00:00

abstract：:The arrival of infected travelers from endemic regions can trigger sustained autochthonous transmission of mosquito-borne pathogens in Europe. In 2007 a Chikungunya outbreak was observed in central Italy, mostly affecting two villages characterised by a high density of Aedes albopictus. The outbreak was mitigated thro...

journal_title：Scientific reports

authors： Trentini F,Poletti P,Baldacchino F,Drago A,Montarsi F,Capelli G,Rizzoli A,Rosà R,Rizzo C,Merler S,Melegaro A

更新日期：2018-06-13 00:00:00

abstract：:Up to now, most of stimulated-emission-depletion (STED) systems were lens-based bulky systems. Exchanging some spatial light paths with optical fiber components will make the systems more flexible and will benefit various fields. A big problem to achieve this goal is that the STED beam generated by the traditional met...

journal_title：Scientific reports

authors： Luo H,Wang G,Yuan L

更新日期：2019-06-11 00:00:00

abstract：:Sepsis induced cardiac dysfunction (SIC) is a severe complication to sepsis which significantly worsens patient outcomes. It is known that bacteria have the capacity to release outer membrane vesicles (OMVs), which are nano-sized bilayered vesicles composed of lipids and proteins, that can induce a fatal inflammatory ...

journal_title：Scientific reports

authors： Svennerholm K,Park KS,Wikström J,Lässer C,Crescitelli R,Shelke GV,Jang SC,Suzuki S,Bandeira E,Olofsson CS,Lötvall J

更新日期：2017-12-12 00:00:00

abstract：:We conducted two online surveys about antibiotics targeted at the Japanese general population in March 2017 and February 2018. In total, 6,982 participants completed the questionnaire. Factors associated with knowledge of antibiotics, knowledge of antimicrobial resistance (AMR) and appropriate behavioural changes were...

journal_title：Scientific reports

authors： Tsuzuki S,Fujitsuka N,Horiuchi K,Ijichi S,Gu Y,Fujitomo Y,Takahashi R,Ohmagari N

更新日期：2020-02-26 00:00:00

abstract：:Silicon has emerged as the most promising high-capacity material for lithium-ion batteries. Waste glass can be a potential low cost and environmentally benign silica resource enabling production of nanosized silicon at the industry level. Windshields are generally made of laminated glass comprising two separate glass ...

journal_title：Scientific reports

authors： Choi M,Kim JC,Kim DW

更新日期：2018-01-17 00:00:00

abstract：:Harvesting light for optical torque is of significant importance, owing to its ability to rotate nano- or micro-objects. Nevertheless, applying a strong optical torque remains a challenging task: angular momentum must conserve but light is limited. A simple argument shows the tendency for two objects with strong mutua...

journal_title：Scientific reports

authors： Chen J,Wang N,Cui L,Li X,Lin Z,Ng J

更新日期：2016-06-13 00:00:00

abstract：:Despite growing acknowledgement of the role of oxidized fatty acids (oxFA) as cellular signaling molecules and in the pathogenesis of disease, developing methods to measure these species in biological samples has proven challenging. Here we describe a novel method utilizing HPLC-ESI-MS/MS to identify and quantify mult...

journal_title：Scientific reports

authors： Ahern KW,Serbulea V,Wingrove CL,Palas ZT,Leitinger N,Harris TE

更新日期：2019-08-01 00:00:00

abstract：:The human brain is lateralised to the right for visuospatial attention, particularly when reorienting attention to unexpected stimuli. However, the developmental characteristics of lateralisation remain unclear. To address this question, we devised a saccade task applicable for both adults and children. To assess the ...

journal_title：Scientific reports

authors： Sanefuji M,Yamashita H,Torio M,Katsuki D,Akamine S,Ishizaki Y,Kishimoto J,Sakai Y,Takada H,Yoshida K,Ohga S

更新日期：2018-05-15 00:00:00

abstract：:Alternative splicing contributes to phenotypic diversity at multiple biological scales, and its dysregulation is implicated in both ageing and age-associated diseases in human. Cross-tissue variability in splicing further complicates its links to age-associated phenotypes and elucidating these links requires a compreh...

journal_title：Scientific reports

authors： Wang K,Wu D,Zhang H,Das A,Basu M,Malin J,Cao K,Hannenhalli S

更新日期：2018-07-19 00:00:00

abstract：:Hungarians who live in Central Europe today are one of the westernmost Uralic speakers. Despite of the proposed Volga-Ural/West Siberian roots of the Hungarian language, the present-day Hungarian gene pool is highly similar to that of the surrounding Indo-European speaking populations. However, a limited portion of sp...

journal_title：Scientific reports

authors： Post H,Németh E,Klima L,Flores R,Fehér T,Türk A,Székely G,Sahakyan H,Mondal M,Montinaro F,Karmin M,Saag L,Yunusbayev B,Khusnutdinova EK,Metspalu E,Villems R,Tambets K,Rootsi S

更新日期：2019-05-24 00:00:00

abstract：:Awe, a complex emotion composed by the appraisal components of vastness and need for accommodation, is a profound and often meaningful experience. Despite its importance, psychologists have only recently begun empirical study of awe. At the experimental level, a main issue concerns how to elicit high intensity awe exp...

journal_title：Scientific reports

authors： Chirico A,Cipresso P,Yaden DB,Biassoni F,Riva G,Gaggioli A

更新日期：2017-04-27 00:00:00

abstract：:RT-qPCR offers high sensitivity, for accurate interpretations of qPCR results however, normalisation using suitable reference genes is fundamental. Androgens can regulate transcriptional expression including reference gene expression in prostate cancer. In this study, we evaluated ten mRNA and six non-protein coding R...

journal_title：Scientific reports

authors： Zhao H,Ma TF,Lin J,Liu LL,Sun WJ,Guo LX,Wang SQ,Otecko NO,Zhang YP

更新日期：2018-01-31 00:00:00

abstract：:The effective differentiation between multiple primary lung tumors (MPs) and intrapulmonary metastases (IMs) in patients is imperative to discover the exact disease stage and to select the most appropriate treatment. In this study, the authors was to evaluate the efficacy and validity of large-scale targeted sequencin...

journal_title：Scientific reports

authors： Duan J,Ge M,Peng J,Zhang Y,Yang L,Wang T,Qin T,Yuan R,Zhang Y,Cheng W

更新日期：2020-11-02 00:00:00

abstract：:Turner Syndrome (TS) is a condition where several genes are affected but the molecular mechanism remains unknown. Identifying the genes that regulate the TS network is one of the main challenges in understanding its aetiology. Here, we studied the regulatory network from manually curated genes reported in the literatu...

journal_title：Scientific reports

authors： Farooqui A,Tazyeen S,Ahmed MM,Alam A,Ali S,Malik MZ,Ali S,Ishrat R

更新日期：2018-07-04 00:00:00

abstract：:Post-infectious bronchiolitis obliterans (BO) could be diagnosed via spirometry and chest computed tomography (CT); however, these tests are limited in infants. We aimed to evaluate the utility of lung clearance index (LCI) and air-trapping lung volume from chest CT in infants. This prospective study included 20 infan...

journal_title：Scientific reports

authors： Kim YH,Shin HJ,Sol IS,Kim SY,Kim JD,Yoon H,Kim KW,Kim MJ,Lee MJ,Sohn MH

更新日期：2017-11-09 00:00:00

abstract：:Type 1 diabetes can be overcome by regulatory T cells (Treg) in NOD mice yet an efficient method to generate and maintain antigen-specific Treg is difficult to come by. Here, we devised a combination therapy of peptide/MHC tetramers and IL-2/anti-IL-2 monoclonal antibody complexes to generate antigen-specific Treg and...

journal_title：Scientific reports

authors： Izquierdo C,Ortiz AZ,Presa M,Malo S,Montoya A,Garabatos N,Mora C,Verdaguer J,Stratmann T

更新日期：2018-05-25 00:00:00

abstract：:Large amounts of anthropogenic CO2 in the atmosphere are taken up by the ocean, which leads to 'ocean acidification' (OA). In addition, the increasing application of nanoparticles inevitably leads to their increased release into the aquatic environment. However, the impact of OA on the bioaccumulation of nanoparticles...

journal_title：Scientific reports

authors： Shi W,Han Y,Guo C,Su W,Zhao X,Zha S,Wang Y,Liu G

更新日期：2019-03-05 00:00:00

abstract：:Although vitamin K deficiency has been implicated in adult inflammatory bowel disease (IBD), its prevalence in pediatric IBD remains unknown. We carried out a cross-sectional study in 63 children with Crohn's disease (CD) and 48 with ulcerative colitis (UC) to assess the prevalence of vitamin K deficiency and to searc...

journal_title：Scientific reports

authors： Nowak JK,Grzybowska-Chlebowczyk U,Landowski P,Szaflarska-Poplawska A,Klincewicz B,Adamczak D,Banasiewicz T,Plawski A,Walkowiak J

更新日期：2014-04-24 00:00:00

abstract：:Approximately 75% of melanomas have known driver oncogenic mutations in BRAF, NRAS, GNA11 or GNAQ, while the mutations providing constitutive oncogenic signaling in the remaining melanomas are not known. We established a melanoma cell line from a tumor with none of the common driver mutations. This cell line demonstra...

journal_title：Scientific reports

authors： Atefi M,Titz B,Tsoi J,Avramis E,Le A,Ng C,Lomova A,Lassen A,Friedman M,Chmielowski B,Ribas A,Graeber TG

更新日期：2016-06-08 00:00:00

abstract：:Parasites alter many traits of their hosts. In particular, parasites known as "manipulative" may increase their probability of transmission by inducing phenotypic alterations in their intermediate hosts. Although parasitic-induced alterations can modify species' ecological roles, the proximate factors modulating this ...

journal_title：Scientific reports

authors： Labaude S,Cézilly F,De Marco L,Rigaud T

更新日期：2020-07-15 00:00:00

abstract：:Understanding the phylogeography and genetic structure of populations and the processes responsible of patterns therein is crucial for evaluating the vulnerability of marine species and developing management strategies. In this study, we explore how past climatic events and ongoing oceanographic and demographic proces...

journal_title：Scientific reports

authors： Garcia-Cisneros A,Palacín C,Ben Khadra Y,Pérez-Portela R

更新日期：2016-09-15 00:00:00