Identification of valid reference genes for mRNA and microRNA normalisation in prostate cancer cell lines.

abstract：:Low haemocompatibility of left ventricular assist devices (LVAD) surfaces necessitates anticoagulative therapy. Endothelial cell (EC) seeding can support haemocompatibility, however, the availability of autologous ECs is limited. In contrast, allogeneic ECs are readily available in sufficient quantity, but HLA dispari...

journal_title：Scientific reports

authors： Figueiredo C,Eicke D,Yuzefovych Y,Avsar M,Hanke JS,Pflaum M,Schmitto JD,Blasczyk R,Haverich A,Wiegmann B

更新日期：2019-08-05 00:00:00

abstract：:Transcriptional enhancers are non-coding segments of DNA that play a central role in the spatiotemporal regulation of gene expression programs. However, systematically and precisely predicting enhancers remain a major challenge. Although existing methods have achieved some success in enhancer prediction, they still su...

journal_title：Scientific reports

authors： Liu F,Li H,Ren C,Bo X,Shu W

更新日期：2016-06-22 00:00:00

abstract：:A relation exists between network proximity of molecular entities in interaction networks, functional similarity and association with diseases. The identification of network regions associated with biological functions and pathologies is a major goal in systems biology. We describe a network diffusion-based pipeline f...

journal_title：Scientific reports

authors： Bersanelli M,Mosca E,Remondini D,Castellani G,Milanesi L

更新日期：2016-10-12 00:00:00

abstract：:Proteins involved in genetic stability maintenance and safeguarding DNA replication act not only against cancer initiation but could also play a major role in sustaining cancer progression. Here, we report that the FANC pathway is highly expressed in metastatic melanoma harboring the oncogenic microphthalmia-associate...

journal_title：Scientific reports

authors： Bourseguin J,Bonet C,Renaud E,Pandiani C,Boncompagni M,Giuliano S,Pawlikowska P,Karmous-Benailly H,Ballotti R,Rosselli F,Bertolotto C

更新日期：2016-11-09 00:00:00

abstract：:For over 60 years, our oceans have been a reservoir for exponentially increasing amounts of plastic waste. Plastic has been documented at all levels of the marine food web, from the deepest oceanic trenches to the most far-flung beaches. Here, we present data on the presence of significant quantities of plastic on the...

journal_title：Scientific reports

authors： Lavers JL,Dicks L,Dicks MR,Finger A

更新日期：2019-05-16 00:00:00

abstract：:A systematic chemomechanical network model for the molecular motor kinesin is presented in this report. The network model is based on the nucleotide-dependent binding affinity of the heads to an microtubule (MT) and the asymmetries and similarities between the chemical transitions caused by the intramolecular strain b...

journal_title：Scientific reports

authors： Sumi T

更新日期：2017-04-25 00:00:00

abstract：:Upper urinary tract urothelial carcinoma (UT-UC) is rare and treatment options or prognostic markers are limited. There is increasing evidence indicating that urothelial carcinoma may be an endocrine-related cancer. The aim of this study was to analyze the prognostic effect of estrogen receptor beta (ERβ) on the outco...

journal_title：Scientific reports

authors： Luo HL,Sung MT,Tsai EM,Lin CS,Lee NL,Chung YH,Chiang PH

更新日期：2016-04-07 00:00:00

abstract：:Ferroelectric-relaxor behavior of Ba(Zr0.3Ti0.7)O3 nanofibers (BZT NF) with a large aspect ratio were prepared via electrospinning and surface modified by PVP as dielectric fillers. The nanocomposite flexible films based on surface modified BZT NF and polyvinylidene fluoride (PVDF) were fabricated via a solution casti...

journal_title：Scientific reports

authors： Liu S,Xue S,Xiu S,Shen B,Zhai J

更新日期：2016-05-17 00:00:00

abstract：:RNA is transcribed from DNA, and therefore, there should be no RNA transcript from the deleted DNA region. Our study attempted to analyse whether any RNA cache that maps the deleted regions is present in human cells. Using data from the 1000 genome project, we selected 41 CEPH (CEU) and 38 Yoruba (YRI) samples that in...

journal_title：Scientific reports

authors： Byeon B,Kovalchuk I

更新日期：2016-11-17 00:00:00

abstract：:The impacts of ecosystem engineers may be expected to vary along environmental gradients. Due to some resources being more limited in arid than in mesic environments, disturbances created by burrowing mammals are expected to have a greater ameliorating effect in arid environments, with larger differences in microhabit...

journal_title：Scientific reports

authors： Louw MA,Haussmann NS,le Roux PC

更新日期：2019-12-18 00:00:00

abstract：:Recent studies on next-generation permanent magnets have focused on filling in the gap between rare-earth magnets and rare-earth-free magnets, taking into account both the cost-effectiveness and magnetic performance of the magnetic materials. As an improved rare-earth-free magnet candidate, here, Ca-substituted M-type...

journal_title：Scientific reports

authors： Lee J,Lee EJ,Hwang TY,Kim J,Choa YH

更新日期：2020-09-28 00:00:00

abstract：:Microbial secondary metabolites are valuable resources for novel drug discovery. In particular, actinomycetes expressed a range of antibiotics against a spectrum of bacteria. In genus level, strain Allosalinactinospora lopnorensis CA15-2(T) is the first new actinomycete isolated from the Lop Nor region, China. Antimic...

journal_title：Scientific reports

authors： Huang C,Leung RK,Guo M,Tuo L,Guo L,Yew WW,Lou I,Lee SMY,Sun C

更新日期：2016-02-11 00:00:00

abstract：:Speckle, amplitude fluctuations in optical coherence tomography (OCT) images, contains information on sub-resolution structural properties of the imaged sample. Speckle statistics could therefore be utilized in the characterization of biological tissues. However, a rigorous theoretical framework relating OCT speckle s...

journal_title：Scientific reports

authors： Almasian M,van Leeuwen TG,Faber DJ

更新日期：2017-11-01 00:00:00

abstract：:In this paper, we study a system with two interacting qubits described by the Heisenberg model with dissipative terms, and analyze decay dynamics and the steady-state of geometric quantum discords. Our results indicate that we can ignore the interaction force in the z-direction and adjust the parameters to change the ...

journal_title：Scientific reports

authors： Liang J,Zhang C

更新日期：2020-07-02 00:00:00

abstract：:Haematopoietic cells arise from endothelial cells within the dorsal aorta of the embryo via a process called the endothelial-haematopoietic transition (EHT). This process crucially depends on the transcription factor RUNX1 which rapidly activates the expression of genes essential for haematopoietic development. Using ...

journal_title：Scientific reports

authors： Gilmour J,Assi SA,Noailles L,Lichtinger M,Obier N,Bonifer C

更新日期：2018-07-10 00:00:00

abstract：:The airways of individuals with cystic fibrosis (CF) are abundantly colonised by Staphylococcus aureus and Pseudomonas aeruginosa. Co-infecting hypoxic regions of static mucus within CF airways, together with decreases in pulmonary function, mucus plugging and oxygen consumption by host neutrophils gives rise to regio...

journal_title：Scientific reports

authors： Pallett R,Leslie LJ,Lambert PA,Milic I,Devitt A,Marshall LJ

更新日期：2019-05-01 00:00:00

abstract：:Unnatural chiral α-amino acids are widely used in fields of organic chemistry, biochemistry and medicinal chemistry, and their synthesis has attracted extensive attention. Although the asymmetric synthesis provides some efficient protocols, noble and elaborate catalysts, ligands and additives are usually required whic...

journal_title：Scientific reports

authors： Jiang M,Jin Y,Yang H,Fu H

更新日期：2016-05-17 00:00:00

abstract：:Here we report exquisitely distinct material properties of primary vascular smooth muscle (VSM) cells isolated from the thoracic aorta of adult (8 months) vs. aged (30 months) F344XBN rats. Individual VSM cells derived from the aged animals showed a tense internal network of the actin cytoskeleton (CSK), exhibiting in...

journal_title：Scientific reports

authors： Zhu W,Kim BC,Wang M,Huang J,Isak A,Bexiga NM,Monticone R,Ha T,Lakatta EG,An SS

更新日期：2018-02-08 00:00:00

abstract：:Absolute numbers of lymphocytes are decreased in uninfected infants born to HIV-1-infected women (HIV-1-exposed). Although the exact mechanism is unknown, fetal exposure to maternal HIV-1-infection could prime the immune system and affect T cell trafficking. We compared the expression of chemokine receptors on cord bl...

journal_title：Scientific reports

authors： Bunders MJ,van Hamme JL,Jansen MH,Boer K,Kootstra NA,Kuijpers TW

更新日期：2014-10-24 00:00:00

abstract：:The Turin Shroud is traditionally considered to be the burial cloth in which the body of Jesus Christ was wrapped after his death approximately 2000 years ago. Here, we report the main findings from the analysis of genomic DNA extracted from dust particles vacuumed from parts of the body image and the lateral edge use...

journal_title：Scientific reports

authors： Barcaccia G,Galla G,Achilli A,Olivieri A,Torroni A

更新日期：2015-10-05 00:00:00

abstract：:Experiments on the Ultimatum Game (UG) repeatedly show that people's behaviour is far from rational. In UG experiments, a subject proposes how to divide a pot and the other can accept or reject the proposal, in which case both lose everything. While rational people would offer and accept the minimum possible amount, i...

journal_title：Scientific reports

authors： Han X,Cao S,Bao JZ,Wang WX,Zhang B,Gao ZY,Sánchez A

更新日期：2018-01-19 00:00:00

abstract：:Joubert syndrome (JS) is an inherited ciliopathy characterized by a distinctive cerebellar and brain stem malformation which is known as the "molar tooth sign" on axial brain images, hypotonia, and developmental delay. Approximately 25-30% of patients with JS have kidney disease and many of them progress to end-stage ...

journal_title：Scientific reports

authors： Takagi Y,Miura K,Yabuuchi T,Kaneko N,Ishizuka K,Takei M,Yajima C,Ikeuchi Y,Kobayashi Y,Takizawa T,Hisano M,Tsurusaki Y,Matsumoto N,Hattori M

更新日期：2021-01-11 00:00:00

abstract：:Cholesterol 25-hydroxylase (CH25H) encodes the enzyme that converts cholesterol to 25-hydroxycholesterol (25-HC). 25-HC has been demonstrated to be involved in the pathogenesis of inflammatory bowel disease. However, the role of CH25H in experimental colitis remains unknown. Dextran sulfate sodium (DSS)-induced coliti...

journal_title：Scientific reports

authors： Sheng N,Ma Z,Zhou Y,Xu J,Gao Y,Fu XY

更新日期：2020-08-28 00:00:00

abstract：:Many human introns carry out a function, in the sense that they are critical to maintain normal cellular activity. Their identification is fundamental to understanding cellular processes and disease. However, being noncoding elements, such functional introns are poorly predicted based on traditional approaches of sequ...

journal_title：Scientific reports

authors： Chorev M,Joseph Bekker A,Goldberger J,Carmel L

更新日期：2017-06-23 00:00:00

abstract：:Gram-negative bacteria belonging to the genus Klebsiella are important nosocomial pathogens, readily acquiring resistance to all known antibiotics. Bacteriocins, non-antibiotic antibacterial proteins, have been earlier proposed as potential therapeutic agents for control of other Gram-negative species such as Escheric...

journal_title：Scientific reports

authors： Denkovskienė E,Paškevičius Š,Misiūnas A,Stočkūnaitė B,Starkevič U,Vitkauskienė A,Hahn-Löbmann S,Schulz S,Giritch A,Gleba Y,Ražanskienė A

更新日期：2019-10-28 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Fülep C,Kovács I,Kránitz K,Erdei G

更新日期：2019-11-22 00:00:00

abstract：:A highly sensitive microwave near-field sensor based on electrically-small planar resonators is proposed for highly accurate characterization of dielectric materials. The proposed sensor was developed in a robust complete-cycle topology optimization procedure wherein first the sensing area was pixelated. By maximizing...

journal_title：Scientific reports

authors： Saadat-Safa M,Nayyeri V,Ghadimi A,Soleimani M,Ramahi OM

更新日期：2019-09-16 00:00:00

abstract：:The UCSC Cancer Genomics Browser (https://genome-cancer.ucsc.edu) offers interactive visualization and exploration of TCGA genomic, phenotypic, and clinical data, as produced by the Cancer Genome Atlas Research Network. Researchers can explore the impact of genomic alterations on phenotypes by visualizing gene and pro...

journal_title：Scientific reports

authors： Cline MS,Craft B,Swatloski T,Goldman M,Ma S,Haussler D,Zhu J

更新日期：2013-10-02 00:00:00

abstract：:It was previously demonstrated that microRNA-199a (miR-199a) was down-regulated in testicular germ cell tumor (TGCT) partially caused by hypermethylation of its promoter. miR-199a is encoded by two loci in the human genome, miR-199a-1 on chromosome (Chr) 19 and miR-199a-2 on Chr 1. Both loci encode the same miR-199a. ...

journal_title：Scientific reports

authors： Chen BF,Suen YK,Gu S,Li L,Chan WY

更新日期：2014-09-18 00:00:00

abstract：:It is widely acknowledged that transcriptional diversity largely contributes to biological regulation in eukaryotes. Since the advent of second-generation sequencing technologies, a large number of RNA sequencing studies have considerably improved our understanding of transcriptome complexity. However, it still remain...

journal_title：Scientific reports

authors： Chen SY,Deng F,Jia X,Li C,Lai SJ

更新日期：2017-08-09 00:00:00