Streamflow variations across the Andes (18°-55°S) during the instrumental era.

abstract：:This research investigated the association between prolonged disposable diaper (DD) wearing in infancy and primary enuresis (PNE). As a case-control study, we collected data from 376 children with enuresis and 379 healthy children who were sex- and age-matched at three tertiary care institutions in mainland China from...

journal_title：Scientific reports

authors： Li X,Wen JG,Shen T,Yang XQ,Peng SX,Wang XZ,Xie H,Wu XD,Du YK

更新日期：2020-09-01 00:00:00

abstract：:It has been hypothesised that speed information, encoded by 'speed cells', is important for updating spatial representation in the hippocampus and entorhinal cortex to reflect ongoing self-movement during locomotion. However, systematic characterisation of speed representation is still lacking. In this study, we compa...

journal_title：Scientific reports

authors： Iwase M,Kitanishi T,Mizuseki K

更新日期：2020-01-29 00:00:00

abstract：:Desertification due to climate change and increasing drought periods is a worldwide problem for both ecology and economy. Our ability to understand how vegetation manages to survive and propagate through arid and semiarid ecosystems may be useful in the development of future strategies to prevent desertification, pres...

journal_title：Scientific reports

authors： Bordeu I,Clerc MG,Couteron P,Lefever R,Tlidi M

更新日期：2016-09-21 00:00:00

abstract：:The spirochete Leptospira spp. can move in liquid and on a solid surface using two periplasmic flagella (PFs), and its motility is an essential virulence factor for the pathogenic species. Mammals are infected with the spirochete through the wounded dermis, which implies the importance of behaviors on the boundary wit...

journal_title：Scientific reports

authors： Abe K,Kuribayashi T,Takabe K,Nakamura S

更新日期：2020-08-18 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Beaudry-Richard A,Nadeau-Vallée M,Prairie É,Maurice N,Heckel É,Nezhady M,Pundir S,Madaan A,Boudreault A,Hou X,Quiniou C,Sierra EM,Beaulac A,Lodygensky G,Robertson SA,Keelan J,Adams Waldorf KM,Olson DM,Rivera JC,Lube

更新日期：2020-04-15 00:00:00

abstract：:Glycan-protein lateral interactions have gained increased attention as important modulators of receptor function, by regulating surface residence time and endocytosis of membrane glycoproteins. The pathogen-recognition receptor DC-SIGN is highly expressed at the membrane of antigen-presenting dendritic cells, where it...

journal_title：Scientific reports

authors： Te Riet J,Joosten B,Reinieren-Beeren I,Figdor CG,Cambi A

更新日期：2017-07-27 00:00:00

abstract：:In bacteria, the SecA ATPase provides the driving force for protein secretion via the SecYEG translocon. While the dynamic interplay between SecA and SecYEG in translocation is widely appreciated, it is not clear how SecA associates with the translocon in the crowded cellular environment. We use super-resolution micro...

journal_title：Scientific reports

authors： Seinen AB,Spakman D,van Oijen AM,Driessen AJM

更新日期：2021-01-14 00:00:00

abstract：:We used Mendelian randomization to estimate the causal effects of the liver enzymes, alanine aminotransferase (ALT), alkaline phosphatase (ALP) and gamma glutamyltransferase (GGT), on diabetes and cardiovascular disease, using genetic variants predicting these liver enzymes at genome wide significance applied to exten...

journal_title：Scientific reports

authors： Liu J,Au Yeung SL,Lin SL,Leung GM,Schooling CM

更新日期：2016-12-20 00:00:00

abstract：:Tumor progression, limited efficacy of current standard treatments, and the rise in patient mortality are associated with gene expression caused by the synergistic action of intratumoral hypoxia and HIF-1α activation. For this reason, recent investigations have focused on HIF-targeting therapeutic agents, with encoura...

journal_title：Scientific reports

authors： Mangraviti A,Raghavan T,Volpin F,Skuli N,Gullotti D,Zhou J,Asnaghi L,Sankey E,Liu A,Wang Y,Lee DH,Gorelick N,Serra R,Peters M,Schriefer D,Delaspre F,Rodriguez FJ,Eberhart CG,Brem H,Olivi A,Tyler B

更新日期：2017-11-02 00:00:00

abstract：:Using species distribution models and information on genetic structure and within-population variance observed in a series of common garden trials, we reconstructed a historical biogeography of trembling aspen in North America. We used an ensemble classifier modelling approach (RandomForest) to reconstruct palaeoclima...

journal_title：Scientific reports

authors： Ding C,Schreiber SG,Roberts DR,Hamann A,Brouard JS

更新日期：2017-07-05 00:00:00

abstract：:Protein phosphorylation is one of the most prevalent and well-understood protein modifications. Oxidation of protein-bound methionine, which has been traditionally perceived as an inevitable damage derived from oxidative stress, is now emerging as another modification capable of regulating protein activity during stre...

journal_title：Scientific reports

authors： Veredas FJ,Cantón FR,Aledo JC

更新日期：2017-01-12 00:00:00

abstract：:Cellular membrane distortion invokes variations in cellular physiology. However, lack of an appropriate system to control the stress and facilitate molecular analyses has hampered progress of relevant studies. In this study, a microfluidic system that finely manipulates membrane distortion of Chlamydomonas reinhardtii...

journal_title：Scientific reports

authors： Min SK,Yoon GH,Joo JH,Sim SJ,Shin HS

更新日期：2014-04-14 00:00:00

abstract：:Since its recent foundation, phase-coherent caloritronics has sparkled continuous interest giving rise to numerous concrete applications. This research field deals with the coherent manipulation of heat currents in mesoscopic superconducting devices by mastering the Josephson phase difference. Here, we introduce a new...

journal_title：Scientific reports

authors： Guarcello C,Solinas P,Braggio A,Giazotto F

更新日期：2018-08-16 00:00:00

abstract：:More and more researchers are interested in and focused on how a limited repertoire of antibodies can bind and correspondingly protect against an almost limitless diversity of invading antigens. In this work, a series of 200-ns molecular dynamics (MD) simulations followed by principal component (PC) analysis and free ...

journal_title：Scientific reports

authors： Chen J,Wang J,Zhu W

更新日期：2016-11-10 00:00:00

abstract：:If a cultural feature is transmitted over generations and exposed to stochastic selection when spreading in a population, its evolution may be governed by statistical laws and be partly predictable, as in the case of genetic evolution. Music exhibits steady changes of styles over time, with new characteristics develop...

journal_title：Scientific reports

authors： Nakamura E,Kaneko K

更新日期：2019-11-05 00:00:00

abstract：:Surface-enhanced Raman spectroscopy (SERS) is considered a highly promising technology for different analytical purposes. The applications of SERS are still quite limited due its relatively poor quantitative repeatability and the fact that SERS is very sensitive to oxidation, which is a challenge especially with silve...

journal_title：Scientific reports

authors： Matikainen A,Nuutinen T,Itkonen T,Heinilehto S,Puustinen J,Hiltunen J,Lappalainen J,Karioja P,Vahimaa P

更新日期：2016-11-16 00:00:00

abstract：:Micro-tube experiment has been implemented to understand the mechanisms of governing microcosmic fluid percolation and is extensively used in both fields of micro electromechanical engineering and petroleum engineering. The measured pressure difference across the microtube is not equal to the actual pressure differenc...

journal_title：Scientific reports

authors： Wang S,Liu P,Zhao H,Zhang Y

更新日期：2017-11-29 00:00:00

abstract：:Heart failure after myocardial infarction (MI) depends on infarct size and adverse left ventricular (LV) remodelling, both influenced by the inflammatory response. Leukocyte-associated immunoglobulin-like receptor 1 (LAIR-1) is an inhibitory receptor of ITAM-dependent cell activation, present on almost all immune cell...

journal_title：Scientific reports

authors： Ellenbroek GHJM,de Haan JJ,van Klarenbosch BR,Brans MAD,van de Weg SM,Smeets MB,de Jong S,Arslan F,Timmers L,Goumans MTH,Hoefer IE,Doevendans PA,Pasterkamp G,Meyaard L,de Jager SCA

更新日期：2017-12-21 00:00:00

abstract：:Despite extensive efforts in studying radioactive aerosols, including the transmission of radionuclides in different chemical matrices throughout the body, the internal organ-specific radiation dose due to inhaled radioactive aerosols has largely relied on experimental deposition data and simplified human phantoms. Co...

journal_title：Scientific reports

authors： Talaat K,Xi J,Baldez P,Hecht A

更新日期：2019-11-25 00:00:00

abstract：:We report on chemical reactions triggered by core-level ionization of ammonium ([Formula: see text]) cation in aqueous solution. Based on a combination of photoemission experiments from a liquid microjet and high-level ab initio simulations, we identified simultaneous single and double proton transfer occurring on a v...

journal_title：Scientific reports

authors： Hollas D,Pohl MN,Seidel R,Aziz EF,Slavíček P,Winter B

更新日期：2017-04-07 00:00:00

abstract：:In this study, we describe a web-based resource, developed for assisting the scientific community in designing an effective therapeutics against the Ebola virus. Firstly, we predicted and identified experimentally validated epitopes in each of the antigens/proteins of the five known ebolaviruses. Secondly, we generate...

journal_title：Scientific reports

authors： Dhanda SK,Chaudhary K,Gupta S,Brahmachari SK,Raghava GP

更新日期：2016-04-26 00:00:00

abstract：:Short QT syndrome (SQTS) is a rare condition characterized by abnormally 'short' QT intervals on the ECG and increased susceptibility to cardiac arrhythmias and sudden death. This simulation study investigated arrhythmia dynamics in multi-scale human ventricle models associated with the SQT2-related V307L KCNQ1 'gain-...

journal_title：Scientific reports

authors： Adeniran I,Whittaker DG,El Harchi A,Hancox JC,Zhang H

更新日期：2017-08-16 00:00:00

abstract：:Understanding the innate immune response to vaccination is critical in vaccine design. Here, we studied blood innate myeloid cells after first and second immunization of cynomolgus macaques with the modified vaccinia virus Ankara. The inflammation at the injection site was moderate and resolved faster after the boost....

journal_title：Scientific reports

authors： Palgen JL,Tchitchek N,Elhmouzi-Younes J,Delandre S,Namet I,Rosenbaum P,Dereuddre-Bosquet N,Martinon F,Cosma A,Lévy Y,Le Grand R,Beignon AS

更新日期：2018-02-15 00:00:00

abstract：:Measuring toxicity is one of the main steps in drug development. Hence, there is a high demand for computational models to predict the toxicity effects of the potential drugs. In this study, we used a dataset, which consists of four toxicity effects:mutagenic, tumorigenic, irritant and reproductive effects. The propos...

journal_title：Scientific reports

authors： Tharwat A,Moemen YS,Hassanien AE

更新日期：2016-12-09 00:00:00

abstract：:Cell fate decisions are controlled by the interplay of transcription factors and epigenetic modifiers, which together determine cellular identity. Here we elaborate on the role of miR302 in the regulation of cell plasticity. Overexpression of miR302 effected silencing of the TGFβ type II receptor and facilitated plast...

journal_title：Scientific reports

authors： De Chiara L,Andrews D,Watson A,Oliviero G,Cagney G,Crean J

更新日期：2017-02-14 00:00:00

abstract：:Parthenocarpy is the development of an ovary into a seedless fruit without pollination. The ubiquitous downregulation of SlIAA9 induces not only parthenocarpic fruit formation but also an abnormal vegetative phenotype. To make parthenocarpic transgenic tomato plants without unwanted phenotypes, we found two genes, nam...

journal_title：Scientific reports

authors： Kim JS,Ezura K,Lee J,Ariizumi T,Ezura H

更新日期：2019-12-11 00:00:00

abstract：:The elastic responsiveness of single cellulose nanofibres is important for advanced analysis of biological tissues and their use in sophisticated functional materials. However, the mechanical responsiveness derived from the twisted structure of cellulose nanofibres (CNFs) has remained unexplored. In this study, finite...

journal_title：Scientific reports

authors： Uetani K,Uto T,Suzuki N

更新日期：2021-01-12 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： McCloskey MC,Shaheen S,Rabago L,Hulverson MA,Choi R,Barrett LK,Arnold SLM

更新日期：2020-02-11 00:00:00

abstract：:Bispecific killer cells engagers (BiKEs) which can bind to natural killer (NK) cells through the activating receptor CD16A and guide them to cells expressing the HIV-1 envelope glycoprotein (Env) are a promising new weapon for elimination of infected cells and eradication of the virus. Here we report the design, gener...

journal_title：Scientific reports

authors： Li W,Wu Y,Kong D,Yang H,Wang Y,Shao J,Feng Y,Chen W,Ma L,Ying T,Dimitrov DS

更新日期：2017-08-22 00:00:00

abstract：:Double quantum dots (DQDs) are a versatile platform for solid-state physics, quantum computation and nanotechnology. The micro-fabrication techniques commonly used to fabricate DQDs are difficult to extend to the atomic scale. Using an alternative approach, which relies on scanning tunneling microscopy and spectroscop...

journal_title：Scientific reports

authors： Zheng H,Zhang J,Berndt R

更新日期：2017-09-07 00:00:00