当前位置： SCI文献检索 > DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY期刊下所有文献 > Five subfamilies of β-defensin genes are present in salmonids: Evolutionary insights and expression analysis in Atlantic salmon Salmo salar.

Five subfamilies of β-defensin genes are present in salmonids: Evolutionary insights and expression analysis in Atlantic salmon Salmo salar.

Abstract：

:β-defensins (BD) are the largest family of vertebrate defensins with potent antimicrobial, chemotactic and immune-regulatory activities. Four BD genes (BD1-4) have been cloned previously in rainbow trout but none have been reported in other salmonids. In this study seven BD genes (BD1a-b, 2-4, 5a-b) are characterised in Atlantic salmon and additional BD genes (BD1b and BD5) in rainbow trout. Bioinformatic analysis revealed up to seven BD genes in the genomes of other salmonids that belong to five subfamilies (BD1-5) due to whole genome duplications. BD1-2 and BD4-5 are also present in basal teleosts but only BD1 and/or BD5 are present in advanced teleosts due to loss of one chromosomal locus. BD3 is salmonid specific. Fish BD have a unique three-coding exon structure. Fish BD are highly divergent between subfamilies but conserved within each subfamily. Atlantic salmon BD genes are differentially expressed in tissues, often with low level expression in systemic immune organs (head kidney and spleen) yet with at least one BD gene highly expressed in mucosal tissues, heart, blood and liver. This suggests an important role of these BD genes in innate immunity in mucosa, liver and blood in Atlantic salmon.

journal_name

Dev Comp Immunol

journal_title

Developmental and comparative immunology

authors

Harte A,Tian G,Xu Q,Secombes CJ,Wang T

doi

10.1016/j.dci.2019.103560

subject

Has Abstract

pub_date

2020-03-01 00:00:00

pages

103560

eissn

0145-305X

issn

1879-0089

pii

S0145-305X(19)30453-7

journal_volume

104

pub_type

杂志文章

相关文献

DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY文献大全
  • Identification and characterization of the first reptilian CD9, and its expression analysis in response to bacterial infection.

    abstract：:In this study, a CD9 homologue in a reptile, Chinese soft-shelled turtle, has been cloned and identified for the first time. The full-length cDNA of turtle CD9 was 1146bp and contained a 672bp open reading frame (ORF) coding for a protein of 224 amino acids. Four transmembrane domains (TMs) divided the turtle CD9 into...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2009.09.001

    authors： Zhou X,Feng H,Guo Q,Dai H

    更新日期：2010-02-01 00:00:00

  • Shark class II invariant chain reveals ancient conserved relationships with cathepsins and MHC class II.

    abstract：:The invariant chain (Ii) is the critical third chain required for the MHC class II heterodimer to be properly guided through the cell, loaded with peptide, and expressed on the surface of antigen presenting cells. Here, we report the isolation of the nurse shark Ii gene, and the comparative analysis of Ii splice varia...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2011.09.008

    authors： Criscitiello MF,Ohta Y,Graham MD,Eubanks JO,Chen PL,Flajnik MF

    更新日期：2012-03-01 00:00:00

  • Determinants of defence strategies of a hibernating European bat species towards the fungal pathogen Pseudogymnoascus destructans.

    abstract：:Pseudogymnoascus destructans (Pd), the causative agent of white-nose syndrome in North America, has decimated bat populations within a decade. The fungus impacts bats during hibernation when physiological functions, including immune responses, are down-regulated. Studies have shown that Pd is native to Europe, where i...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2021.104017

    authors： Fritze M,Puechmaille SJ,Costantini D,Fickel J,Voigt CC,Czirják GÁ

    更新日期：2021-01-18 00:00:00

  • Lipopolysaccharide- and β-1,3-glucan-binding protein from Fenneropenaeus merguiensis functions as a pattern recognition receptor with a broad specificity for diverse pathogens in the defense against microorganisms.

    abstract：:In crustaceans, lipopolysaccharide- and β-1,3-glucan-binding protein (LGBP) plays an important role in innate immunity by mediating the recognition of pathogens to host cells. Hereby, LGBP was cloned from Fenneropenaeus merguiensis hepatopancreas. Its full-length cDNA (1280 bp) had an open reading frame of 1101 bp, en...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2016.07.006

    authors： Chaosomboon A,Phupet B,Rattanaporn O,Runsaeng P,Utarabhand P

    更新日期：2017-02-01 00:00:00

  • Differential expression and functional diversification of diverse immunoglobulin domain-containing protein (DICP) family in three gynogenetic clones of gibel carp.

    abstract：:Diverse immunoglobulin (Ig) domain-containing protein (DICP) family is a novel bony fish-specific multi-gene family encoding diversified immune receptors. However, their function and the implication of binding partners remain unknown. In this study, we first identified 28 DICPs from three gibel carp gynogenetic clones...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2018.03.013

    authors： Gao FX,Lu WJ,Wang Y,Zhang QY,Zhang YB,Mou CY,Li Z,Zhang XJ,Liu CW,Zhou L,Gui JF

    更新日期：2018-07-01 00:00:00

  • IRF11 regulates positively type I IFN transcription and antiviral response in mandarin fish, Siniperca chuatsi.

    abstract：:In vertebrates, a total of eleven interferon (IFN) regulatory factors (IRFs), IRF1 to IRF11 are reported, with the conserved presence of IRF1 to IRF9 in all classes of vertebrates. However, IRF10 has been reported only in fish and birds, and IRF11 seems to be a fish specific IRF member. In this study, IRF11 in mandari...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2020.103846

    authors： Li L,Chen SN,Nie P

    更新日期：2021-01-01 00:00:00

  • Molecular identification and expression analysis of TAB1 from orange-spotted grouper (Epinephelus coioides).

    abstract：:Transforming growth factor-β activated kinase 1 (TAK1) is a crucial signal transducer in multiple signaling pathways. TAK1 binds TAB1, TAB2, and TAB3, which act as activators and adaptors that specifically regulate the activation of TAK1. To date, the role of TABs is largely unknown in fish. In the present study, a TA...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2018.09.014

    authors： Hu YZ,Li X,Han R,Jiang B,Li YW,Dan XM,Li AX

    更新日期：2019-01-01 00:00:00

  • The roles of antimicrobial peptide, rip-thanatin, in the midgut of Riptortus pedestris.

    abstract：:Recently, we have reported the structural determination of antimicrobial peptides (AMPs), such as riptocin, rip-defensin, and rip-thanatin, from Riptortus pedestris. However, the biological roles of AMPs in the host midgut remain elusive. Here, we compared the expression levels of AMP genes in apo-symbiotic insects wi...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2017.09.009

    authors： Park KE,Jang SH,Lee J,Lee SA,Kikuchi Y,Seo YS,Lee BL

    更新日期：2018-01-01 00:00:00

  • Identification and functional characterization of the house finch interleukin-1β.

    abstract：:Interleukin-1β (IL-1β), an inflammatory cytokine of the IL-1 family, is primarily produced as a precursor protein by monocytes and macrophages, then matures and becomes activated through proteolytic catalysis. Although the biological characteristics of avian IL-1β are well known, little information is available about ...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2016.12.004

    authors： Park M,Kim S,Adelman JS,Leon AE,Hawley DM,Dalloul RA

    更新日期：2017-04-01 00:00:00

  • GATA3 mRNA in ginbuna crucian carp (Carassius auratus langsdorfii): cDNA cloning, splice variants and expression analysis.

    abstract：:GATA3, a transcriptional activator, plays a critical role in the development of T-cells and differentiation to T helper type 2 cells. To date, no information is available on the role of GATA3 in the teleost immune system. We identified full-length cDNA and alternatively spliced variants of ginbuna crucian carp GATA3 (...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2008.01.004

    authors： Takizawa F,Mizunaga Y,Araki K,Moritomo T,Ototake M,Nakanishi T

    更新日期：2008-01-01 00:00:00

  • Molecular and functional characterization of a mannose-binding lectin/ficolin-associated protein (MAp44) from Nile tilapia (Oreochromis niloticus) involved in the immune response to bacterial infection.

    abstract：:The lectin pathway of the complement system has a pivotal role in the defense against infectious organisms. Mannose-binding lectin/ficolin-associated protein (MAp44), a multifunctional complement regulator, regulates the complement activation by competing with MASP-1, MASP-2 and MASP-3 for MBL and ficolin binding site...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2019.103438

    authors： Mu L,Wu H,Han K,Wu L,Bian X,Li B,Guo Z,Yin X,Ye J

    更新日期：2019-12-01 00:00:00

  • Immunorecognition in the freshwater bivalve, Corbicula fluminea. II. Isolation and characterization of a plasma opsonin with hemagglutinating activity.

    abstract：:Opsonizing and agglutinating activities of plasma from the freshwater clam, Corbicula fluminea, were found to be inhibited by the sugars, 2-deoxy-D-glucose (deoxy-Glu) and N-acetyl-D-galactosamine (GalNAc). The plasma opsonin/agglutinin was subsequently isolated by a two-step separation procedure. Aldehyde-fixed rabbi...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/0145-305x(90)90032-a

    authors： Yang R,Yoshino TP

    更新日期：1990-10-01 00:00:00

  • Avian IgY is selectively incorporated into the egg yolks of oocytes by discriminating Fc amino acid residues located on the Cυ3/Cυ4 interface.

    abstract：:In avian species, maternal IgY is selectively incorporated into the egg yolks of maturing oocytes, but the relevance of receptor-mediated uptake is unclear. Here we investigated the critical amino acid residues of IgY required for egg yolk transport by conducting mutational analyses of selected residues located along ...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2012.12.003

    authors： Murai A,Murota R,Doi K,Yoshida T,Aoyama H,Kobayashi M,Horio F

    更新日期：2013-04-01 00:00:00

  • Studies on colony specificity in the compound ascidian, Botryllus primigenus Oka. II. In vivo bioassay for analyzing the mechanism of "nonfusion" reaction.

    abstract：:Fusion experiments with three colonies (AC-BC-BD) by Tanaka and Watanabe indicated that the mixture of blood from two nonfusible colonies induced a "nonfusion" reaction (NFR)-like responses. Thus, artificial mixture of the blood from two nonfusible colonies is expected to result in NFR-like reactions. The present stud...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/s0145-305x(82)80007-4

    authors： Taneda Y,Watanabe H

    更新日期：1982-04-01 00:00:00

  • Antibody production in sharks and humans: a role for natural antibodies.

    abstract：:Although gene segments specifying Igs of all vertebrates show clear homology, their arrangements differ markedly, thereby suggesting that the mechanisms for the generation of diversity and for the regulation of gene expression may be quite distinct. In the sandbar shark, light chain gene segments are distributed as ap...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/0145-305x(93)90014-h

    authors： Marchalonis JJ,Hohman VS,Thomas C,Schluter SF

    更新日期：1993-01-01 00:00:00

  • Melanization inhibition protein of Penaeus monodon acts as a negative regulator of the prophenoloxidase-activating system.

    abstract：:Melanization mediated by the prophenoloxidase-activating system (proPO) is an important immune response in invertebrates. However, in addition to melanin, the proPO system produces reactive intermediates that are not only harmful to the invading microbes but also to the host cells. Thus, the proPO system must be tight...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2017.02.014

    authors： Noothuan N,Amparyup P,Tassanakajon A

    更新日期：2017-07-01 00:00:00

  • Molecular cloning and characterization of interferon regulatory factor 1 (IRF-1), IRF-2 and IRF-5 in the chondrostean paddlefish Polyodon spathula and their phylogenetic importance in the Osteichthyes.

    abstract：:The interferon regulatory factor (IRF) with its 10 members is a very important gene family related to innate immunity. Currently, most fish IRFs reported are from bony fish (teleosts). Cloning and sequencing of IRFs from chondrosteans, the so-called "ancient fish" including sturgeon, paddlefish, bichir and gar, are ab...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2011.06.003

    authors： Xiaoni G,Zhuo C,Xuzhen W,Dengqiang W,Xinwen C

    更新日期：2012-01-01 00:00:00

  • Characterization of immunoglobulin light chain utilization and variable family diversity in rainbow trout.

    abstract：:This study characterizes immunoglobulin light chain (IgL) expression and variable family usage in rainbow trout. IgL transcripts were generated by 5' RACE from both immune and TNP-KLH immunized fish. Phylogenetic analysis revealed that the IgL variable regions clustered into seven different families: three kappa famil...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2019.103566

    authors： Rego K,Bengtén E,Wilson M,Hansen JD,Bromage ES

    更新日期：2020-03-01 00:00:00

  • Light chain variable region diversity in Atlantic cod (Gadus morhua L.).

    abstract：:This study was undertaken to determine if a lack of V(L) domain variability could explain, in part, the failure of Atlantic cod to respond to immunization with the production of specific antibodies. The variability of cod V(L) regions was studied in 33 cDNA and two genomic clones. The variability of the CDRs was estim...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/s0145-305x(99)00003-8

    authors： Widholm H,Lundbäck AS,Daggfeldt A,Magnadottir B,Warr GW,Pilström L

    更新日期：1999-04-01 00:00:00

  • Molecular characterization, phylogeny and expression of a hepcidin gene in the blotched snakehead Channa maculata.

    abstract：:A hepcidin-like gene (cmHep) was cloned and characterized from the liver of the blotched snakehead Channa maculata. The complete cmHep cDNA was 756 bp in length, containing an open reading frame of 270 bp (encoding 89 amino acids), flanked by 210 bp and 276 bp of 5' and 3' untranslated regions, respectively. The deduc...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2013.11.007

    authors： Gong LC,Wang H,Deng L

    更新日期：2014-05-01 00:00:00

  • Differential cytokine mRNA expression in single lymphatic follicles of the calf ileal and jejunal Peyer's patches.

    abstract：:The ruminant gut-associated lymphoid tissues are broadly classified into ileal and jejunal Peyer's patches (PP). We isolated single lymphatic follicles from ileal and jejunal PP and examined mRNA expression of 13 cytokines using RT-PCR. Four patterns of differential expression were identified. In Pattern 1, the cytoki...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2008.09.007

    authors： Yasuda M,Nasu T,Murakami T

    更新日期：2009-04-01 00:00:00

  • Goldfish (Carassius auratus L.) as a model system to study the growth factors, receptors and transcription factors that govern myelopoiesis in fish.

    abstract：:The process of myeloid cell development (myelopoiesis) in fish has mainly been studied in three cyprinid species: zebrafish (Danio rerio), ginbuna carp (Carassius auratus langsdorfii) and goldfish (C. auratus, L.). Our studies on goldfish myelopoiesis have utilized in vitro generated primary kidney macrophage (PKM) cu...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章,评审

    doi：10.1016/j.dci.2015.10.024

    authors： Katzenback BA,Katakura F,Belosevic M

    更新日期：2016-05-01 00:00:00

  • Different sensitivity to the dexamethasone treatment of the lymphoid organs of Rana perezi in two different seasons.

    abstract：:Adult female frogs (Rana perezi) have been used to analyze structural and morphometrical changes which affect lymphoid organs after treatment with a single dose of dexamethasone (DX). Special attention was given to the distinct sensitivity observed during two different periods of the year. Morphological differences we...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/0145-305x(89)90017-7

    authors： Garrido E,Gomariz RP,Leceta J,Zapata A

    更新日期：1989-01-01 00:00:00

  • Characterization of two isoforms of Japanese spiny lobster Panulirus japonicus defensin cDNA.

    abstract：:Antimicrobial peptides (AMPs) are components of the innate immune responses that form the first line of host defense against pathogens. In this study, cDNAs of two new isoforms of defensin (designated PJD1 and PJD2) from a Japanese spiny lobster Panulirus japonicus haemocytes cDNA library were cloned and sequenced. PJ...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2008.11.007

    authors： Pisuttharachai D,Yasuike M,Aono H,Yano Y,Murakami K,Kondo H,Aoki T,Hirono I

    更新日期：2009-04-01 00:00:00

  • Antibody-dependent cellular cytotoxicity in poikilotherms.

    abstract：:51Cr-chromate labelled chicken red blood cells, treated with rabbit (anti-chicken red blood cell) serum, are lysed in vitro, in the absence of complement, by spleen cells from Xenopus laevis, Ambystoma mexicanum or Lacerta viridis. Optimal conditions for lysis by Xenopus spleen cells were determined. The phenomenon se...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/s0145-305x(77)80017-7

    authors： Jurd RD,Doritis A

    更新日期：1977-10-01 00:00:00

  • Characterisation of chicken OX40 and OX40L.

    abstract：:The Tumour Necrosis Factor superfamilies of receptors and ligands play a crucial role in the regulation of effective immune responses against pathogens and malignant cells. In chickens, only few members have been identified. Here, we characterise the chicken homologues for mammalian costimulatory molecules OX40 and OX...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2018.01.014

    authors： Scherer S,Göbel TW

    更新日期：2018-05-01 00:00:00

  • Transcriptome analysis of hagfish leukocytes: a framework for understanding the immune system of jawless fishes.

    abstract：:Jawless fishes occupy a critical phylogenetic position in understanding the origin of the adaptive immune system. Here, we performed large-scale expressed sequence tag analysis of leukocytes isolated from the inshore hagfish Eptatretus burgeri. Although we found many immunity-related genes such as those involved in ly...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2004.04.005

    authors： Suzuki T,Shin-I T,Kohara Y,Kasahara M

    更新日期：2004-08-01 00:00:00

  • Characterization, evolution, and expression analysis of TLR7 gene subfamily members in Mastacembelus armatus (Synbranchiformes: Mastacembelidae).

    abstract：:TLR7 subfamily members are important pattern recognition receptors participating in the recognition of pathogen-associated molecular patterns. In this study, we successfully identified 3 members of TLR7 subfamily from the spiny eel Mastacembelus armatus (MaTLR7, MaTLR8 and MaTLR9). The amino acid sequence identities o...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/j.dci.2019.02.002

    authors： Han C,Li Q,Liu J,Hao Z,Huang J,Zhang Y

    更新日期：2019-06-01 00:00:00

  • Lipopolysaccharide activates the sea urchin immune system.

    abstract：:Profilin is a small, actin-binding protein that functions at the intersection of signal transduction and cytoskeletal modifications. Increases in the number of profilin messages per cell correlate with sea urchin coelomocytes activation in response to injury. Here we show that coelomocytes respond to immune challenge ...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/0145-305x(95)00009-i

    authors： Smith LC,Britten RJ,Davidson EH

    更新日期：1995-05-01 00:00:00

  • An alternative internal splicing site defines new Ikaros isoforms in Pleurodeles waltl.

    abstract：:The Ikaros gene encodes a family of transcription factors which plays a crucial role in hematopoiesis. To improve our knowledge about the immune system of Pleurodeles waltl, we sequenced the cDNA coding for the Ik-1 isoform of that salamander and analyzed its tissue expression by semi-quantitative RT-PCR. Ikaros trans...

    journal_title：Developmental and comparative immunology

    pub_type： 杂志文章

    doi：10.1016/s0145-305x(02)00014-9

    authors： Boudarra N,Frippiat C,Dournon C,Frippiat JP

    更新日期：2002-09-01 00:00:00