CHST15 promotes the proliferation of TE‑1 cells via multiple pathways in esophageal cancer.

abstract：:Chemokines have been reported to play crucial roles in tumor progression. Eotaxin-1 (CCL11), a member of the CC chemokine family, is elevated in many types of human cancer. Here, to reveal the molecular mechanisms of eotaxin-1 in prostate cancer cell invasion, the expression of eotaxin-1 receptors [CC chemokine recept...

journal_title：Oncology reports

authors： Zhu F,Liu P,Li J,Zhang Y

更新日期：2014-05-01 00:00:00

abstract：:The Houttuynia cordata Thunb (HCT) extract has been used as a traditional Chinese herb medicine and as well as an effective drug for treating allergic inflammation for thousands of years. In this study, we investigated the anti-cancer activity of HCT and its molecular mechanisms in the human colon adenocarcinoma cell ...

journal_title：Oncology reports

authors： Tang YJ,Yang JS,Lin CF,Shyu WC,Tsuzuki M,Lu CC,Chen YF,Lai KC

更新日期：2009-11-01 00:00:00

abstract：:Although radiotherapy is routinely administered to high-risk endometrial carcinoma and offer a significant disease-free survival advantage, the therapeutic effect is sometimes limited by the occurrence of radioresistance. To determine the patterns of gene expression responsible for the radioresistance and to search fo...

journal_title：Oncology reports

authors： Du XL,Jiang T,Wen ZQ,Li QS,Gao R,Wang F

更新日期：2009-03-01 00:00:00

abstract：:As one of the most common malignancies, esophageal squamous cell carcinoma (ESCC) is ranked as the sixth leading cause of cancer-related death worldwide. In our previous study, by employing cDNA microarray analysis, semaphorin 3B (SEMA3B) was found to be significantly downregulated in ESCC. In the present study, SEMA3...

journal_title：Oncology reports

authors： Tang H,Wu Y,Liu M,Qin Y,Wang H,Wang L,Li S,Zhu H,He Z,Luo J,Wang H,Wang Q,Luo S

更新日期：2016-08-01 00:00:00

abstract：:To clarify hepatocarcinogenesis by the heterocyclic amine, 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx), we investigated the global expression of genes in rat liver. Rats were continuously fed MeIQx 100 ppm in their diet, and were sacrificed at weeks 4 and 16 for early time points, and week 104 for tumor samp...

journal_title：Oncology reports

authors： Kang JS,Wanibuchi H,Murai T,Morimura K,Kinoshita A,Fukushima S

更新日期：2007-04-01 00:00:00

abstract：:Previously, we showed that the herbal extract EYK (Epimedium koreanum Nakai) can regulate the immune response. Other studies showed that EYK has beneficial effects in human lung cancer, angiogenesis and Alzheimer's disease (AD). However, it remains unknown whether EYK can affect cancer cell migration and invasion in h...

journal_title：Oncology reports

authors： Lee W,Nam JH,Cho HJ,Lee JY,Cho WK,Kim Υ,We YM,Ma JY,Hoe HS

更新日期：2017-12-01 00:00:00

abstract：:Antimycin A (AMA) inhibits the mitochondrial electron transport between cytochromes b and c. However, the relationship between AMA and lung cancer cells is poorly understood. In this study, we investigated the involvement of reactive oxygen species (ROS) and glutathione (GSH) in AMA-treated lung cancer Calu-6 cell dea...

journal_title：Oncology reports

authors： Han YH,Park WH

更新日期：2009-01-01 00:00:00

abstract：:The aims of the present study were to review the experience of different surgical reconstruction methods for hypopharyngeal squamous cell carcinoma (HSCC) and compared the survival of patients with and without laryngeal function (LF) preservation. The clinical characteristics of 580 patients were retrospectively obtai...

journal_title：Oncology reports

authors： Zhou J,Li Y,Wei D,Qian Y,Li W,Liu D,Li G,Pan X,Lei D

更新日期：2015-12-01 00:00:00

abstract：:Pancreatic cancer is one of the most lethal cancers, with an incidence equaling mortality. It is a heterogeneous group of neoplasms in which pancreatic ductal adenocarcinoma is most common. Pancreatic cancer cannot be cured even if detected early. When treatment is initiated, a suit...

journal_title：Oncology reports

authors： Takata T,Ishigaki Y,Shimasaki T,Tsuchida H,Motoo Y,Hayashi A,Tomosugi N

更新日期：2012-12-01 00:00:00

abstract：:MicroRNAs (miRNAs) play important roles in the the gene regulation of carcinogenesis including breast cancer. miR‑519d has been studied in various types of cancer, but its role in breast cancer remains unclear. In the present study, we investigated the expression and biological function of miR-519d in breast cancer. U...

journal_title：Oncology reports

authors： Deng X,Zhao Y,Wang B

更新日期：2015-10-01 00:00:00

abstract：:Mesenchymal stem cells (MSCs) are known to migrate to tumor tissues and to play an important role in cancer progression. However, the effects of MSCs on tumor progression remain controversial. The purpose of the present study was to detect the effects of human umbilical cord-derived MSCs (hUC‑MSCs) on the human breast...

journal_title：Oncology reports

authors： Li T,Zhang C,Ding Y,Zhai W,Liu K,Bu F,Tu T,Sun L,Zhu W,Zhou F,Qi W,Hu J,Chen H,Sun X

更新日期：2015-09-01 00:00:00

abstract：:Migration and adhesion of tumor cells are essential prerequisites for the formation of metastases in malignant diseases. Chemokine receptor 7 (CCR7) has been shown to regulate integrin which can then facilitate adhesion of cancer cells to and/or migration through the extracellular matrix (ECM). In order to identify th...

journal_title：Oncology reports

authors： Li P,Zhao ZJ,Liu FY,Sun LY,Ding X,Zhang WZ,Shang DH,Sun CF

更新日期：2010-10-01 00:00:00

abstract：:DNA double-strand breaks (DSBs) induced by ionizing radiation (IR) are among the most cytotoxic types of DNA damage. The DNA damage response (DDR) may be a reason for the cancer cell resistance to radiotherapy using IR. Identified as critical upstream mediators of the phosphorylation of ataxia telangiectasia-mutated (...

journal_title：Oncology reports

authors： Gou Q,Xie Y,Liu L,Xie K,Wu Y,Wang Q,Wang Z,Li P

更新日期：2015-07-01 00:00:00

abstract：:Ovarian cancer (OC) is a common cancer of the human genital system. Circular RNAs (circRNAs) play an important role in carcinogenesis and progression of various cancers. The present study aimed to clarify the expression profile and functions of circ‑FAM53B in the progression of OC and reveal its underlying mechanisms....

journal_title：Oncology reports

authors： Sun D,Liu J,Zhou L

更新日期：2019-12-01 00:00:00

abstract：:Though patients with EGFR mutations are initially responsive to EGFR-tyrosine kinase inhibitors (TKIs), most tumors ultimately acquire resistance to EGFR-TKIs. The most frequently reported mechanism is EGFR T790M mutation. In this study, using a droplet digital PCR (ddPCR) system, we assessed optimal conditions for a ...

journal_title：Oncology reports

authors： Suzawa K,Yamamoto H,Ohashi K,Hashida S,Tomida S,Kubo T,Maki Y,Soh J,Tsukuda K,Kiura K,Miyoshi S,Toyooka S

更新日期：2017-05-01 00:00:00

abstract：:Activating mutations of Ras gene families have been found in a variety of human malignancies, including lung cancer, suggesting their dominant role in tumorigenesis. Many studies have showed that the Kras gene is activated by point mutations in approximately 15-20% of non-small cell lung cancers (NSCLCs), however, the...

journal_title：Oncology reports

authors： Sasaki H,Okuda K,Kawano O,Endo K,Yukiue H,Yokoyama T,Yano M,Fujii Y

更新日期：2007-09-01 00:00:00

abstract：:CD44 has diverse functions in cell-cell and cell-matrix interactions and may be a determinant of metastatic and invasive behaviour in carcinomas. CD44 variant 6 (CD44v6) has been postulated to be involved in both carcinogenesis and tumor progression. Therefore, we have examined CD44v6 expression in tumors from 57 pati...

journal_title：Oncology reports

authors： Bendardaf R,Lamlum H,Ristamäki R,Pyrhönen S

更新日期：2004-01-01 00:00:00

abstract：:Beta1-6 branching of L-PHA reactive oligosaccharides, one of the N-glycan structures, plays an important role in the biological behavior of various tumor cell lines. We reported previously that the expression of L-PHA reactive oligosaccharides was closely associated with the prognosis of patients with human diffuse la...

journal_title：Oncology reports

authors： Suzuki O,Nozawa Y,Abe M

更新日期：2005-01-01 00:00:00

abstract：:Mutations of the von Hippel-Lindau (VHL) tumor suppressor gene cause hereditary and sporadic renal cell carcinomas (RCCs). The best characterized function of VHL protein is suppression of the α subunit of hypoxia inducible factor (HIF). Additional VHL functions have been reported, including induction of senescence upo...

journal_title：Oncology reports

authors： Macher-Goeppinger S,Bermejo JL,Schirmacher P,Pahernik S,Hohenfellner M,Roth W

更新日期：2013-11-01 00:00:00

abstract：:Immunotherapy of cancer offers great promise, however translation into human studies has yielded relatively poor results to date. The concept of combining cancer vaccination with angiogenesis inhibition is appealing, due to favorable safety profile of both approaches, as well as possible biological synergies. Here we ...

journal_title：Oncology reports

authors： Chan RC,Gutierrez B,Ichim TE,Lin F

更新日期：2009-11-01 00:00:00

abstract：:Gastroenteropancreatic neuroendocrine tumors (GEP‑NETs) are relatively uncommon. Unfortunately, epidemiological studies on the incidence of GEP‑NETs worldwide have reported a marked increase in the detection of these tumors. Although they often exhibit relatively indolent clinical courses, GEP‑NETs have the potential ...

journal_title：Oncology reports

authors： Tang C,Gong L,Zou W,Zhang J,Zhou Y,Wu X,Lu F,Ouyang C,Liu X

更新日期：2016-12-01 00:00:00

abstract：:Despite tremendous effort and progress in the diagnostics of pancreatic cancer with respect to imaging techniques and molecular genetics, only very few patients can be cured by surgery leading to a 5-year survival rate of only 3%. Especially the lack of chemotherapeutical options in this entity requires a better under...

journal_title：Oncology reports

authors： Domagk D,Schaefer KL,Eisenacher M,Braun Y,Wai DH,Schleicher C,Diallo-Danebrock R,Bojar H,Roeder G,Gabbert HE,Domschke W,Poremba C

更新日期：2007-02-01 00:00:00

abstract：:Investigations into extracellular vesicles (EVs) have significantly increased since their role in physiological and pathological processes has become more clearly understood. Furthermore, it has become increasingly clear that several subpopulations of EVs exist, such as exosomes (EXOs) and microvesicles (MVs). Various...

journal_title：Oncology reports

authors： Giusti I,Di Francesco M,Cantone L,D'Ascenzo S,Bollati V,Carta G,Dolo V

更新日期：2015-11-01 00:00:00

abstract：:MicroRNAs (miRNAs) play crucial roles in the initiation and progression of various cancers, including melanoma. Recently, the genetic variants and deregulation of miR-605 have been reported to participate in carcinogenesis. However, the expression status of the miR-605 in melanoma tissues and its role in melanoma prog...

journal_title：Oncology reports

authors： Chen L,Cao Y,Rong D,Wang Y,Cao Y

更新日期：2017-08-01 00:00:00

abstract：:During the initial emergency operation, a temporary loop colostomy (TLC) was constructed at the oral border of the region for subsequent radical resection. Then, radical surgery was performed by hybrid 2-port HALS (Mukai's operation) using the TLC as the hand access site. Left hemicolectomy was done in three patients,...

journal_title：Oncology reports

authors： Mukai M,Sekido Y,Hoshikawa T,Yazawa N,Fukumitsu H,Okada K,Tajima T,Nakamura M,Ogoshi K

更新日期：2010-07-01 00:00:00

abstract：:Vaccine strategies for the treatment of human papillomavirus-induced cervical cancer are based mainly on the human papillomavirus 16 E7 (HPV16 E7) oncoprotein. The immunogenicity of the E7 gene has been enhanced by its fusion to many different genes. Here, we linked a short sequence coding for the E7 peptide (aa 44-60...

journal_title：Oncology reports

authors： Pokorna D,Cerovska N,Smahel M,Moravec T,Ludvikova V,Mackova J,Synkova H,Duskova M,Hozak P,Veleminsky J

更新日期：2005-10-01 00:00:00

abstract：:A phase II trial of vinorelbine and low dose prednisone in hormone-refractory metastatic prostate cancer was conducted in order to investigate its safety, efficacy and impact on quality of life. Vinorelbine was administered at the dose of 25 mg/m(2) i.v. weekly for 12 weeks and then biweekly, along with 10 mg of daily...

journal_title：Oncology reports

authors： Robles C,Furst AJ,Sriratana P,Lai S,Chua L,Donnelly E,Solomon J,Sundaram M,Feun L,Savaraj N

更新日期：2003-07-01 00:00:00

abstract：:In vivo real-time visualization of chemotherapy response at the cellular level provides us with direct evidence of what happens on the tumor microenvironment of metastatic organs. We imaged the response of metastatic tumor cells and host stromal cells to chemotherapeutics on liver m...

journal_title：Oncology reports

authors： Tanaka K,Okigami M,Toiyama Y,Morimoto Y,Matsushita K,Kawamura M,Hashimoto K,Saigusa S,Okugawa Y,Inoue Y,Uchida K,Araki T,Mohri Y,Mizoguchi A,Kusunoki M

更新日期：2012-11-01 00:00:00

abstract：:Although chemotherapy is initially effective in debulking tumor mass in a number of different types of malignancy, tumor cells gradually acquire chemoresistance and frequently progress to advanced clinical stage. Accumulating evidence has indicated that the tumor sensitivity to several chemotherapeutic drugs is regula...

journal_title：Oncology reports

authors： Tomita R,Sasabe E,Tomomura A,Yamamoto T

更新日期：2020-11-01 00:00:00

abstract：:In the present study, the preliminary results of the first stereotactic body radiosurgery (SRS) experience with volumetric intensity modulated arc therapy (VMAT) in oligometastatic breast and recurrent gynecological tumors (OBRGT) are reported in terms of feasibility, toxicity and efficacy. Patients were treated in a ...

journal_title：Oncology reports

authors： Macchia G,Deodato F,Cilla S,Torre G,Corrado G,Legge F,Gambacorta MA,Tagliaferri L,Mignogna S,Scambia G,Valentini V,Morganti AG,Ferrandina G

更新日期：2014-11-01 00:00:00