当前位置： SCI文献检索 > INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES期刊下所有文献 > Structural characterization of arabinogalactan extracted from Ixeris chinensis (Thunb.) Nakai and its immunomodulatory effect on RAW264.7 macrophages.

Structural characterization of arabinogalactan extracted from Ixeris chinensis (Thunb.) Nakai and its immunomodulatory effect on RAW264.7 macrophages.

Abstract：

:An arabinogalactan (ICPA) was isolated from the water extract of Ixeris chinensis (Thunb.) Nakai. ICPA was mainly composed of galactose and arabinose with minor amount of glucose. The molecular weight of ICPA was 58.1 kDa. Structural analysis by methylation and NMR spectroscopy indicated that ICPA contained α-D-Glcp(1→, →5)-α-L-Araf(1→, β-D-Galf(1→, →3)-β-D-Galf(1→, β-D-Galp(1→, →6)-β-D-Galp(1→, and → 3,6)-β-D-Galp(1→, and that the molar ratio of the sugar residues was about 0.1:1.0:0.1:0.2:1.1:1.0:1.3, respectively. The immunomodulatory activity on RAW264.7 cells was measured in vitro. ICPA stimulated RAW 264.7 cell proliferation at 25-400 μg/mL in a dose-dependent manner. ICPA also enhanced phagocytosis, and the secretion of NO, TNF-α, and IL-6 by the cells. The results suggested the potential utilization of ICPA as an immunomodulatory agent.

journal_name

Int J Biol Macromol

journal_title

International journal of biological macromolecules

authors

Li H,Xie W,Qiao X,Cui H,Yang X,Xue C

doi

10.1016/j.ijbiomac.2019.09.158

subject

Has Abstract

pub_date

2020-01-15 00:00:00

pages

977-983

eissn

0141-8130

issn

1879-0003

pii

S0141-8130(19)34615-X

journal_volume

143

pub_type

杂志文章

相关文献

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES文献大全
  • Tuning the formation and stability of microcapsules by environmental conditions and chitosan structure.

    abstract：:The goal of this work is to tune the formation and stability of the alginate-chitosan (AC) polyelectrolyte complexes (PECs) and microcapsules. Particularly, we explore the role of the conformation of chitosan on its interaction with alginate to understand the mechanism underpinning their interactions at the molecular ...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2016.06.034

    authors： Ren Y,Xie H,Liu X,Yang F,Yu W,Ma X

    更新日期：2016-10-01 00:00:00

  • Interactions between flavonoids and hemoglobin in lecithin liposomes.

    abstract：:In this paper, the binding of flavonoids (quercetin and rutin) to hemoglobin (Hb) have been investigated by fluorescence, absorption spectroscopy and circular dichroism (CD) spectroscopy. The binding parameters and binding mode between flavonoids and Hb are determined and the results of CD and synchronous fluorescence...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2006.08.011

    authors： Xi J,Guo R

    更新日期：2007-03-10 00:00:00

  • Xyloglucan-based hybrid nanocomposite with potential for biomedical applications.

    abstract：:Natural polymer-based hybrid nanocomposites have been proposed as one of the most promising tools for biomedical applications, including disease treatment and diagnosis procedures. Xyloglucan nanocapsules can simultaneously load magnetic iron oxide nanoparticles and bioactive for a specific tissue, reducing the proces...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2020.11.128

    authors： da Silva ACC,de Almeida RR,da Cruz Sousa AC,Martínez FNA,Denardin JC,de Morais SM,Ricardo NMPS

    更新日期：2021-01-31 00:00:00

  • Role of peroxynitrite induced structural changes on H2B histone by physicochemical method.

    abstract：:Histones are small highly conserved cationic proteins which bind DNA and remain confined in the nucleus. These histones are quite vulnerable to oxidizing and nitrating agents. Peroxynitrite is a powerful oxidant and nitrating agent present in the biological system. In this study, peroxynitrite-induced nitration and ox...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2015.10.085

    authors： Khan MA,Alam K,Dixit K,Rizvi MM

    更新日期：2016-01-01 00:00:00

  • Structure of spherical viruses.

    abstract：:This review summarizes some of the results obtained from the crystal structure determination of viruses. The structural similarities of viral coat proteins is discussed, as well as some structural results related to the regulation of viral disassembly. ...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/0141-8130(91)90026-q

    authors： Liljas L

    更新日期：1991-10-01 00:00:00

  • Alginate-magnetic short nanofibers 3D composite hydrogel enhances the encapsulated human olfactory mucosa stem cells bioactivity for potential nerve regeneration application.

    abstract：:The design of 3D hydrogel constructs to elicit highly controlled cell response is a major field of interest in developing tissue engineering. The bioactivity of encapsulated cells inside pure alginate hydrogel is limited by its relatively inertness. Combining short nanofibers within a hydrogel serves as a promising me...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2020.11.199

    authors： Karimi S,Bagher Z,Najmoddin N,Simorgh S,Pezeshki-Modaress M

    更新日期：2021-01-15 00:00:00

  • Enzymatic degradation of poly(hydroxyalkanoates) by Pseudomonas pickettii.

    abstract：:A bacterium capable of degrading poly(3-hydroxybutyrate) [P(3HB)] was isolated from laboratory media and identified as Pseudomonas pickettii. The strain P. pickettii excreted an extracellular poly(hydroxyalkanoate) (PHA) depolymerase and grew on P(3HB) as the sole carbon source. P. pickettii also grew on 3-hydroxybuty...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/0141-8130(93)90040-s

    authors： Yamada K,Mukai K,Doi Y

    更新日期：1993-08-01 00:00:00

  • Ginger polysaccharides induced cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells.

    abstract：:In this study, ginger polysaccharide (GP) was obtained from ginger by enzymatic method, its chemical properties and antitumor activity were investigated. The results indicated that the composition and proportion of GP were l‑rhamnose, d‑arabinose, d‑mannose, d‑glucose and d‑galactose in a molar ratio of 3.64:5.37:3.04...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2018.10.169

    authors： Wang Y,Wang S,Song R,Cai J,Xu J,Tang X,Li N

    更新日期：2019-02-15 00:00:00

  • Development of a new paper based nano-biosensor using the co-catalytic effect of tyrosinase from banana peel tissue (Musa Cavendish) and functionalized silica nanoparticles for voltammetric determination of l-tyrosine.

    abstract：:In this paper, a new and facile method for the electrochemical determination of l-tyrosine was designed. First, 3-mercaptopropyl trimethoxysilane-functionalized silica nanoparticles were added to a paper disc. Then, the banana peel tissue and the mediator potassium hexacyanoferrate were dropped onto the paper, respect...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2018.02.060

    authors： Rahimi-Mohseni M,Raoof JB,Ojani R,Aghajanzadeh TA,Bagheri Hashkavayi A

    更新日期：2018-07-01 00:00:00

  • Structural alteration of low pH, low temperature induced protonated form of DNA to the canonical form by the benzophenanthridine alkaloid nitidine: Spectroscopic exploration.

    abstract：:Polymorphism of DNA plays a very important part of research relating to the drug-DNA interactions. Here main focus of our investigation is to monitor the interaction of the benzophenanthridine plant alkaloid, nitidine (NIT) with two different forms of DNA i.e. B-DNA and protonated form of DNA maintaining proper temper...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2018.08.031

    authors： Haque L,Bhuiya S,Giri I,Chowdhury S,Das S

    更新日期：2018-11-01 00:00:00

  • Analysis of hydrodynamic data for denatured globular proteins in terms of the wormlike cylinder model.

    abstract：:Hydrodynamic data, i.e. intrinsic viscosity and sedimentation coefficient, for denatured globular proteins in 6 M guanidinium chloride have been re-analysed in terms of the Yamakawa-Fujii theory of the wormlike cylinder model. Molecular parameters thus obtained ((mean value of R2 0/M) infinity, the Kuhn statistical se...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/0141-8130(91)90078-9

    authors： Bohdanecký M,Petrus V

    更新日期：1991-08-01 00:00:00

  • Fabrication and characterization of novel bilayer scaffold from nanocellulose based aerogel for skin tissue engineering applications.

    abstract：:The aim of this study was to fabricate a novel bilayer scaffold containing cellulose nanofiber/poly (vinyl) alcohol (CNF/PVA) to evaluate its potential use in skin tissue engineering. Here, the scaffolds were fabricated using a novel one-step freeze-drying technique with two different concentrations of the aforementio...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2019.06.104

    authors： Ghafari R,Jonoobi M,Amirabad LM,Oksman K,Taheri AR

    更新日期：2019-09-01 00:00:00

  • Extraction, characterization and in vitro antioxidant activity of polysaccharides from Carex meyeriana Kunth using different methods.

    abstract：:Response surface methodology (RSM) combined with a Box-Behnken design (BBD) was used to optimize the hot-water extraction (HWE) conditions which were determined to be: liquid-solid ratio 29.25:1 mL/g, extraction time 1.66 h, extraction temperature 95 °C, the optimized yield of polysaccharides 0.47 ± 0.01% (n = 3). Hot...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2018.09.125

    authors： Hu Z,Wang P,Zhou H,Li Y

    更新日期：2018-12-01 00:00:00

  • Antioxidant and ion-induced gelation functions of pectins enabled by polyphenol conjugation.

    abstract：:The development of antioxidant polymers through the chemical conjugation of natural polyphenols onto polysaccharides has important applications in biomedical, pharmaceutical, food, and cosmetic fields. Due to their labile characteristics, the covalent conjugation of polyphenols while retaining antioxidant properties h...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2017.03.173

    authors： Ahn S,Halake K,Lee J

    更新日期：2017-08-01 00:00:00

  • Preparation and characterization of solvent-free fluids reinforced and plasticized polylactic acid fibrous membrane.

    abstract：:In this paper, the electronspun Polylactic acid (PLA)/TiO2 nanofluids (nfs) fibrous membrane with good toughness, hydrophilicity and antibacterial activities are fabricated by taking full advantages of solvent-free TiO2 nfs with amphiphilicity and ionic conductivity. The resulting PLA/TiO2 nfs fibrous membrane exhibit...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2020.06.027

    authors： Yu Q,Qin Y,Han M,Pan F,Han L,Yin X,Chen Z,Wang L,Wang H

    更新日期：2020-10-15 00:00:00

  • Polymer coated mesoporous ceramic for drug delivery in bone tissue engineering.

    abstract：:Treatment strategy for various bone fracture and defects the researchers are focusing to develop a new carrier for delivering the drug into injured area with controlled and sustained manner using biomaterials with dynamic architecture orientation. Ceramic materials are resembled with bone compositional architecture an...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章,评审

    doi：10.1016/j.ijbiomac.2017.11.146

    authors： Subhapradha N,Abudhahir M,Aathira A,Srinivasan N,Moorthi A

    更新日期：2018-04-15 00:00:00

  • Poly(methyl methacrylate) films reinforced with coconut shell lignin fractions to enhance their UV-blocking, antioxidant and thermo-mechanical properties.

    abstract：:Lignin is a high added-value product obtained from agrowastes through organosolv process to yield materials for technological applications. Here, coconut shell organosolv lignin was fractionated using green solvents (acetone and ethanol) and incorporated in poly(methyl methacrylate) (PMMA) films. The non-fractionated ...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2018.12.043

    authors： Avelino F,de Oliveira DR,Mazzetto SE,Lomonaco D

    更新日期：2019-03-15 00:00:00

  • Molecular cloning and analysis of the full-length aciniform spidroin gene from Araneus ventricosus.

    abstract：:Orb-web spiders produce more than seven different protein-based silks/glues by specialized abdominal glands for different uses. Prey-wrapping silk is secreted by aciniform glands for wrapping prey and forming the inner layer of egg case, and is almost twice as tough as other silks because of high strength and extensib...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2017.12.090

    authors： Wen R,Wang K,Liu X,Li X,Mi J,Meng Q

    更新日期：2018-10-01 00:00:00

  • Length of polyglutamine tract affects secondary and tertiary structures of huntingtin protein.

    abstract：:The role of polyglutamine (polyQ) tract on protein stability and disease pathology remains ambiguous. We monitored the unfolding/refolding patterns of huntingtin proteins with varying polyQ lengths. In the presence of urea, minor differences in unfolding and refolding efficiencies were observed. However, in the presen...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2012.07.022

    authors： Vachharajani SN,Chaudhary RK,Prasad S,Roy I

    更新日期：2012-12-01 00:00:00

  • Physico-chemical, structural and techno-functional properties of gelatin from saithe (Pollachius virens) skin.

    abstract：:Gelatin from saithe (Pollachius virens) skin, with high mineral content, was characterized and compared to marine gelatin from the market. As expected, gelatin extracted from the saithe skin had a high mineral content (>20%), compared to commercial gelatin (<0.2%). SDS-PAGE analysis revealed the presence of α-chains, ...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2020.04.047

    authors： Casanova F,Mohammadifar MA,Jahromi M,Petersen HO,Sloth JJ,Eybye KL,Kobbelgaard S,Jakobsen G,Jessen F

    更新日期：2020-08-01 00:00:00

  • Cross-linked chitosan in nano and bead scales as drug carriers for betamethasone and tetracycline.

    abstract：:Chitosan nanoparticles and chitosan beads were synthesized through the ionic gelation procedure in which sodium citrate was used as the cross-linking agent. The prepared nanoparticles were characterized by using transmission electron microscopy (TEM), X-ray diffraction (XRD), zeta potential, and Fourier transform infr...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2019.03.094

    authors： Taghizadeh MT,Ashassi-Sorkhabi H,Afkari R,Kazempour A

    更新日期：2019-06-15 00:00:00

  • Simultaneous co-immobilization of three enzymes onto a modified glassy carbon electrode to fabricate a high-performance amperometric biosensor for determination of total cholesterol.

    abstract：:In this work, we have fabricated a novel amperometric cholesterol (CHO) biosensor because of the importance of determination of CHO levels in blood which is an important parameter for diagnosis and prevention of disease. To achieve this goal, cholesterol oxidase, cholesterol esterase and horseradish peroxidase were si...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2018.08.163

    authors： Rashidi K,Mahmoudi M,Mohammadi G,Zangeneh MM,Korani S,Goicoechea HC,Gu HW,Jalalvand AR

    更新日期：2018-12-01 00:00:00

  • A thermophilic and thermostable xylanase from Caldicoprobacter algeriensis: Recombinant expression, characterization and application in paper biobleaching.

    abstract：:A novel xylanase gene xynBCA, encoding a polypeptide of 439 residues (XynBCA), was cloned from Caldicoprobacter algeriensis genome and recombinantly expressed in Escherichia coli BL21(DE3). The amino acid sequence analysis showed that XynBCA belongs to the glycoside hydrolase family 10. The purified recombinant enzyme...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2020.07.162

    authors： Mhiri S,Bouanane-Darenfed A,Jemli S,Neifar S,Ameri R,Mezghani M,Bouacem K,Jaouadi B,Bejar S

    更新日期：2020-12-01 00:00:00

  • Preparation, characterization and antibacterial activity of octenyl succinic anhydride modified inulin.

    abstract：:Octenyl succinic anhydride modified inulin (In-OSA) was synthesized via chemical modification of inulin with octenyl succinic anhydride (OSA). The esterification of inulin with OSA was confirmed by Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), and degree of substitution (DS) calc...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2015.03.067

    authors： Zhang X,Zhang YW,Zhang H,Yang Q,Wang H,Zhang G

    更新日期：2015-01-01 00:00:00

  • Molecular interactions in self-assembled nano-structures of chitosan-sodium alginate based polyelectrolyte complexes.

    abstract：:We report here the self-assembled structures of polyelectrolyte complexes (PECs) of polyanionic sodium alginate with the polycationic chitosan at room temperature. The PECs prepared at different pH values exhibited two distinct morphologies. The chitosan-alginate PECs self-assembled into the fibrous structure in a low...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2018.03.075

    authors： Wasupalli GK,Verma D

    更新日期：2018-07-15 00:00:00

  • Interpenetrating network gels with tunable physical properties: Glucono-δ-lactone induced gelation of mixed Alg/gellan sol systems.

    abstract：:In this study, a class of interpenetrating network (IPN) gels were successfully fabricated based on glucono-δ-lactone (GDL) induced gelation of mixed alginate (Alg) and deacylated gellan (gellan) systems. The IPN gels were prepared by co-hydrating a mixed Alg and gellan powder, followed by adding GDL and calcium carbo...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2020.02.107

    authors： Li A,Gong T,Yang X,Guo Y

    更新日期：2020-05-15 00:00:00

  • Comparative effects of limited tryptic hydrolysis on physicochemical and structural features of seed 11S globulins.

    abstract：:The effect of the limited proteolysis by trypsin on selected seed storage 11S globulins (broad bean and pea legumins, glycinin and helianthinin) was studied by high-sensitive differential scanning calorimetry, fluorescence spectroscopy and analysis of proteolysis kinetics. Different behaviour of glycinin and helianthi...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2005.12.006

    authors： Braudo EE,Danilenko AN,Guslyannikov PV,Kozhevnikov GO,Artykova GP,Lapteva NA,Vaintraub IA,Sironi E,Duranti M

    更新日期：2006-11-15 00:00:00

  • Bioinspired sodium alginate based thermosensitive hydrogel membranes for accelerated wound healing.

    abstract：:Despite substantial progress made in the development of wound dressings, wound management remains a great challenge, which compels significant burden to the patient and healthcare system. Owing to its intricate pathophysiology particularly, wounds with bacterial burden impose substantial challenges to the conventional...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2020.03.248

    authors： Abbasi AR,Sohail M,Minhas MU,Khaliq T,Kousar M,Khan S,Hussain Z,Munir A

    更新日期：2020-07-15 00:00:00

  • Protective effect of a polysaccharide from Dipsacus asper Wall on streptozotocin (STZ)-induced diabetic nephropathy in rat.

    abstract：:The effects of a polysaccharide (DAP) from the roots of Dipsacus asper on renal complication in streptozotocin (STZ)-induced diabetic rats were investigated in the present study. Administration of DAP (100 and 300 mg/kg) for 4 weeks significantly decreased the fasting blood glucose (FBG) and glycosylated hemoglobin (H...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2019.04.069

    authors： Li T,Hua Q,Li N,Cui Y,Zhao M

    更新日期：2019-07-15 00:00:00

  • Synthesis, characterization and biomedical applications of a novel Schiff base on methyl acrylate-functionalized chitosan bearing p-nitrobenzaldehyde groups.

    abstract：:Amino-functionalization has gained significant attention in the chemical modification of carbohydrate polymers due to their potential biomedical applications. Here, the preparation of innovative functionalized chitosan bearing amino-containing groups and equipped with p-nitrobenzaldehyde groups, resulting in an aminat...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2018.11.005

    authors： Kenawy ER,Ali SS,Al-Etewy M,Sun J,Wu J,El-Zawawy N

    更新日期：2019-02-01 00:00:00