Interpenetrating network gels with tunable physical properties: Glucono-δ-lactone induced gelation of mixed Alg/gellan sol systems.


:In this study, a class of interpenetrating network (IPN) gels were successfully fabricated based on glucono-δ-lactone (GDL) induced gelation of mixed alginate (Alg) and deacylated gellan (gellan) systems. The IPN gels were prepared by co-hydrating a mixed Alg and gellan powder, followed by adding GDL and calcium carbonate (CaCO3) in sequence to initiate the gelation. It was found that Alg and gellan can form independently a gel network, with no significant interaction between the two types of gel networks observed, as indicated by the results of gel strength determination, scanning electron microscope (SEM) observations and thermogravimetry (TG) and derivative thermogravimetric (DTG) analyses. Moreover, the mixing ratio of Alg to gellan significantly affected the physical properties of the fabricated gels. With increasing Alg to gellan ratio, the gels tended to become more elastic, and to show a higher rehydration rate and rehydration extent. Overall, these tunable properties may allow the fabricated gels to find potential applications in designing or optimizing the structures of gel-related food products.


Int J Biol Macromol


Li A,Gong T,Yang X,Guo Y




Has Abstract


2020-05-15 00:00:00












  • Smart nanoparticles based on pullulan-g-poly(N-isopropylacrylamide) for controlled delivery of indomethacin.

    abstract::Double hydrophilic thermo-responsive pullulan-g-poly(N-isopropylacrylamide) (P-g-pNIPAM) copolymers with two different molecular weight of thermosensitive grafts were synthesized and used for preparation of indomethacin-loaded nanoparticles by dialysis and nanoprecipitation method. The polymers form aggregates in aque...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Constantin M,Bucătariu S,Stoica I,Fundueanu G

    更新日期:2017-01-01 00:00:00

  • Preparation and characterization of broken-rice starch nanoparticles with different sizes.

    abstract::Broken-rice starch nanoparticles with different mean particle diameters for 100, 200, 400 and 800 nm were prepared by nanoprecipitation, alkali freezing, cross-linking and H2SO4 hydrolysis methods respectively, and their structural, morphological and physicochemical properties were systematically characterized. The re...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Xiao H,Yang F,Lin Q,Zhang Q,Zhang L,Sun S,Han W,Liu GQ

    更新日期:2020-10-01 00:00:00

  • Bionic design for surface optimization combining hydrophilic and negative charged biological macromolecules.

    abstract::While polyethersulfone (PES) membrane represents a promising option for blood purification, the blood compatibility must be dramatically enhanced to meet today's ever-increasing demands for many emerging application. In this study, we report a bionic design for optimization and development of a modified PES membrane c...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Ran F,Song H,Niu X,Yang A,Nie S,Wang L,Li J,Sun S,Zhao C

    更新日期:2014-06-01 00:00:00

  • Purification and neuroprotective effects of polysaccharides from Opuntia Milpa Alta in cultured cortical neurons.

    abstract::Opuntia is a traditional plant from China with medicinal applications. In this experiment, polysaccharides from Opuntia Milpa Alta (MAPs) were analyzed using gas chromatograph-mass spectrometer (GC-MS) method and result showed that MAPs contained mannose (6.37%), rhamnose (14.94%), xylose (1.99%), arabinose (24.07%), ...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Chen Y,Zhao B,Huang X,Zhan J,Zhao Y,Zhou M,Guo L

    更新日期:2011-11-01 00:00:00

  • A rapid, accurate and sensitive method for determination of monosaccharides in different varieties of Osmanthus fragrans Lour by pre-column derivatization with HPLC-MS/MS.

    abstract::A specific HPLC-MS/MS (High-Performance Liquid Chromatography with tandem Mass Spectrometry) method was developed and validated for simultaneous determination of several monosaccharides in three kinds Osmanthus fragrans Lour. After extraction, separation, protein removal, pigment removal and hydrolysis, monosaccharide...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Fan B,Li T,Song X,Wu C,Qian C

    更新日期:2019-03-15 00:00:00

  • Immobilization and stabilization of cholesterol oxidase on modified sepharose particles.

    abstract::For the cholesterol oxidase from Brevibacterium sp. M201008 was not stable as free enzyme form, it had been covalently immobilized onto functionalized sepharose particles that were activated with N-ethyl-N'-3-dimethylaminopropyl carbodiimide (EDC).The optimal conditions of enzyme immobilization were determined, and th...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Chen Y,Xin Y,Yang H,Zhang L,Zhang Y,Xia X,Tong Y,Wang W

    更新日期:2013-05-01 00:00:00

  • Structure characterization of two functional polysaccharides from Polygonum multiflorum and its immunomodulatory.

    abstract::Two purified polysaccharides named WPMP-1 and WPMP-2 were obtained from Polygonum multiflorum with an average molecular weight of 2.04kDa and 92.13kDa, respectively. Structural characterization revealed that WPMP-1was supposed to be a glucan composed of 1,4-linked α-d-Glcp, 1,4,6-linked α-d-Glcp, and terminal α-d-Glcp...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Zhang Q,Xu Y,Lv J,Cheng M,Wu Y,Cao K,Zhang X,Mou X,Fan Q

    更新日期:2018-07-01 00:00:00

  • Structural characterization and functional analysis of juvenile hormone diol kinase from the silkworm, Bombyx mori.

    abstract::Juvenile hormone diol kinase (JHDK) is an important enzyme involved in the juvenile hormone metabolism pathway, which catalyzes the phosphorylation of juvenile hormone diol to form the polar metabolite JH diol phosphate. Here, we reported the first crystal structure of insect JHDK from Bombyx mori, BmJHDK-L2, determin...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Xu H,Zhang Y,Zhang L,Wang Z,Guo P,Zhao P

    更新日期:2021-01-15 00:00:00

  • The impact of various exogenous type starch on the structural properties and dispersion stability of autoclaved lotus seed starch.

    abstract::In order to investigate the effects of exogenous V-type starch on the structural properties and dispersion stability of lotus seed starch after autoclave treatment, the crystal structure, molecular structure, and dispersion stability were analyzed and discussed, as well as compared with exogenous A-type and B-type sta...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Zheng Y,Ou Y,Zhang C,Zhang Y,Zheng B,Zeng S,Zeng H

    更新日期:2021-01-29 00:00:00

  • Characterization and antitumor activity of novel exopolysaccharide APS of Lactobacillus plantarum WLPL09 from human breast milk.

    abstract::Two exopolysaccharides, NPS and APS, were isolated from L. plantarum WLPL09 and purified by ion-exchange chromatography. The structural analyses showed that molecular weight of NPS and APS were 72.60 kDa and 33.22 kDa, respectively. NPS was mainly composed of mannose and glucose, in molar ratio of 85.35:14.65, while A...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Jiang B,Tian L,Huang X,Liu Z,Jia K,Wei H,Tao X

    更新日期:2020-11-15 00:00:00

  • Extraction and characterization of three polysaccharides extracted from Opuntia ficus indica cladodes.

    abstract::The chemical extraction and the characterization of polysaccharides from mucilage (MC), pectin (PC) and total pectic mucilage fraction (TFC) of Opuntia ficus indica cladodes as well as the evaluation of their antioxidant activities was investigated. The FTIR spectroscopic analysis revealed the presence of carboxyl and...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Bayar N,Kriaa M,Kammoun R

    更新日期:2016-11-01 00:00:00

  • A thermophilic and thermostable xylanase from Caldicoprobacter algeriensis: Recombinant expression, characterization and application in paper biobleaching.

    abstract::A novel xylanase gene xynBCA, encoding a polypeptide of 439 residues (XynBCA), was cloned from Caldicoprobacter algeriensis genome and recombinantly expressed in Escherichia coli BL21(DE3). The amino acid sequence analysis showed that XynBCA belongs to the glycoside hydrolase family 10. The purified recombinant enzyme...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Mhiri S,Bouanane-Darenfed A,Jemli S,Neifar S,Ameri R,Mezghani M,Bouacem K,Jaouadi B,Bejar S

    更新日期:2020-12-01 00:00:00

  • Sorghum straw: Pulping and bleaching process optimization and synthesis of cellulose acetate.

    abstract::The process employed for the pulping and bleaching of sorghum straw was optimized prior to the synthesis of cellulose acetate. A 22 factorial central composite design was carried out. The variables considered were cooking time (1.5 to 2.5 h) and dilute alkali concentration (0.75 to 1.25%) for the pulping and bleaching...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Andrade Alves JA,Lisboa Dos Santos MD,Morais CC,Ramirez Ascheri JL,Signini R,Dos Santos DM,Cavalcante Bastos SM,Ramirez Ascheri DP

    更新日期:2019-08-15 00:00:00

  • Physicochemical properties and digestibility of potato starch treated by ball milling with tea polyphenols.

    abstract::Native potato starch (NPS) with tea polyphenols (TPs) was treated in a planetary ball mill, and the effects of co-grinding on properties and digestibility of starch were studied. The X-ray diffraction (XRD) results showed that the crystal structure of starch granules was destroyed after 7 h of ball grinding, and their...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Lv Y,Zhang L,Li M,He X,Hao L,Dai Y

    更新日期:2019-05-15 00:00:00

  • The differences between fungal α-glucan synthase determining pullulan synthesis and that controlling cell wall α-1,3 glucan synthesis.

    abstract::The fungal α-glucan synthases (Agss) are multi-domain proteins catalyzing biosynthesis of cell wall α-1,3-glucan which determines cell wall integrity or fungal pathogenicity and pullulan which is a maltotriosyl polymer made of α-1,4 and α-1,6 bound glucose units. The Agss family can be divided into 11 groups, some of ...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Qi CY,Jia SL,Wei X,Yang G,Chi Z,Liu GL,Hu Z,Chi ZM

    更新日期:2020-11-01 00:00:00

  • The first mitochondrial genome for Phaudidae (Lepidoptera) with phylogenetic analyses of Zygaenoidea.

    abstract::Phauda flammans Walker belongs to Phaudidae (Lepidoptera), which is a holometabolous and leaf-eating pest that harms trees. So far, there is no mitochondrial (mt) genome reported of Phaudidae. Herein, we sequenced and annotated the complete mt genome of P. flammans representing the first mt genome of Phaudidae and pre...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Zhang R,Li J,Geng S,Yang J,Zhang X,An Y,Li C,Cui H,Li X,Wang Y

    更新日期:2020-04-15 00:00:00

  • Identification of the anchoring protein SpoIIIJ for construction of the microbial cell surface display system in Bacillus spp.

    abstract::Microbial cell surface display technology is a powerful tool for displaying proteins on the surfaces of cells. However, few anchoring proteins can be employed for the display of target proteins on the cell surface of the environmentally benign Gram-positive bacterium Bacillus subtilis. In this study, bioinformatics to...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Ding Z,Guan F,Yu X,Li Q,Wang Q,Tian J,Wu N

    更新日期:2019-07-15 00:00:00

  • 1,3,5-Triazine-2,4,6-tribenzaldehyde derivative as a new crosslinking agent for synthesis of pH-thermo dual responsive chitosan hydrogels and their nanocomposites: Swelling properties and drug release behavior.

    abstract::In this work, 1,3,5-triazine-2,4,6-tribenzaldehyde was synthesized and chosen as the cross-linking agent for preparation of novel thermo- and pH-responsive hydrogels based on chitosan. The cross-linking proceeds through formation of imine bond by reaction of amino groups of chitosan with aldehyde groups of the cross-l...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Karimi AR,Tarighatjoo M,Nikravesh G

    更新日期:2017-12-01 00:00:00

  • Role of Au(III) coordination by polymer in "green" synthesis of gold nanoparticles using chitosan derivatives.

    abstract::Here we report "green" synthesis of gold nanoparticles in solutions of heterocyclic chitosan derivatives (N-(4-imidazolyl)methylchitosan (IMC), N-2-(2-pyridyl)ethylchitosan (2-PEC), and N-2-(4-pyridyl)ethylchitosan (4-PEC)) and show how efficiency of Au(III) binding to polymer influences the Au(III) reduction rate and...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Pestov A,Nazirov A,Privar Y,Modin E,Bratskaya S

    更新日期:2016-10-01 00:00:00

  • Highly reinforced poly(butylene succinate) nanocomposites prepared from chitosan nanowhiskers by in-situ polymerization.

    abstract::Biodegradable aliphatic polyesters need to be tough for commodity-plastic applications, such as disposable bags. Herein, we show that chitosan nanowhiskers (CsWs) prepared from naturally abundant chitin is an effective nanofiller that reinforces the strength and toughness of poly(butylene succinate) (PBS). In-situ pol...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Kim H,Shin MS,Jeon H,Koo JM,Eom Y,Choi S,Shin G,Oh DX,Hwang SY,Park J

    更新日期:2021-01-18 00:00:00

  • Chitosan nanocomposite films based on Ag-NP and Au-NP biosynthesis by Bacillus Subtilis as packaging materials.

    abstract::Chitosan-silver (CS-Ag) and Chitosan-gold (CS-Au) nanocomposites films were synthesized by a simple chemical method. A local bacterial isolate identified as Bacillus subtilis ss subtilis was found to be capable to synthesize both silver nanoparticles (Ag-NP) and gold nanoparticles (Au-NP) from silver nitrate (AgNO3) a...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Youssef AM,Abdel-Aziz MS,El-Sayed SM

    更新日期:2014-08-01 00:00:00

  • Isolation and characterization of Populus xyloglucan endotransglycosylase/hydrolase (XTH) involved in osmotic stress responses.

    abstract::Xyloglucan endotransglycosylase/hydrolase (XTH) belongs to the GH16 subfamily of the glycoside hydrolases of carbohydrate active enzymes and plays an important role in the structure and function of plant cell walls. In this study, 11 members of the XTH gene family were cloned from Populus tomentosa. A bioinformatics a...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Jiang Y,Li Y,Lu C,Tang Y,Jiang X,Gai Y

    更新日期:2020-07-15 00:00:00

  • Immunostimulatory and anti-allergic potential of novel heterotrimeric lectin from seeds of Zizyphus mauritiana Lam.

    abstract::Zizyphus mauritiana Lam. seeds (ZMS) have been used medicinally as sedative or hypnotic drugs in most of Asian countries. ZMS has significant benefits to the human health. Therefore, we have evaluated immunomodulatory effect of lectin extracted from these ZMSL in both in vitro and in vivo study. Anaphylaxis is a sever...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Butle AB,Talmale SA,Jadhao VV,Patil MB,Lambat TL

    更新日期:2021-01-09 00:00:00

  • Antitumor and antimetastatic effects of PLA2-BthTX-II from Bothrops jararacussu venom on human breast cancer cells.

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    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: de Vasconcelos Azevedo FVP,Zóia MAP,Lopes DS,Gimenes SN,Vecchi L,Alves PT,Rodrigues RS,Silva ACA,Yoneyama KAG,Goulart LR,de Melo Rodrigues V

    更新日期:2019-08-15 00:00:00

  • Thermal helix-coil transition in UV irradiated collagen from rat tail tendon.

    abstract::The thermal helix-coil transition in UV irradiated collagen solution, collagen film and pieces of rat tail tendon (RTT) were compared. Their thermal stability's were determined by differential scanning calorimeter (DSC) and by viscometric measurements. The denaturation temperatures of collagen solution, film and piece...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Sionkowska A,Kamińska A

    更新日期:1999-05-01 00:00:00

  • Interaction of heat shock protein 90 B1 (Hsp90B1) with liposome reveals its potential role in protection the integrity of lipid membranes.

    abstract::Heat shock proteins of 90kDa (Hsp90) are molecular chaperones essential for protein homeostasis. Besides chaperone activity, Hsp90 exhibits other cellular functions at membranes, yet how it interacts with membranes remains elusive. We report here that Hsp90B1 interacts with phospholipid membranes. We first cloned the ...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Li P,Zhang M,Zou Y,Sun Z,Sun C,Geng Z,Xu W,Wang D

    更新日期:2018-01-01 00:00:00

  • Development and characterization of a fully human antibody targeting SCF/c-kit signaling.

    abstract::CD117/c-kit, a tyrosine kinase receptor, plays a critical role in hematopoiesis, pigmentation, and fertility. The overexpression and activation of c-kit are thought to promote tumor growth and have been reported in various cancers, including leukemia, glioblastoma and mastocytosis. To disrupt the SCF/c-kit signaling a...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Kim JO,Kim HN,Kim KH,Baek EJ,Park JY,Ha K,Heo DR,Seo MD,Park SG

    更新日期:2020-09-15 00:00:00

  • Coproduction of protease and mannanase from Bacillus nealsonii PN-11 in solid state fermentation and their combined application as detergent additives.

    abstract::Bacillus nealsonii PN-11 produces thermo-alkalistable mannanase and protease active in wide temperature and pH range. Optimization of coproduction of protease and mannanase from this strain and application of cocktail of these enzymes as detergent additives were studied. On optimization mannanase yield of 834Ug-1 (11....

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: David A,Singh Chauhan P,Kumar A,Angural S,Kumar D,Puri N,Gupta N

    更新日期:2018-03-01 00:00:00

  • Cell-specific and pH-sensitive nanostructure hydrogel based on chitosan as a photosensitizer carrier for selective photodynamic therapy.

    abstract::The major problems of porphyrins as promising materials for photodynamic therapy (PDT) are their low solubility, subsequently aggregation in biological environments, and a lack of tumor selectivity. With this in mind, a chitosan-based hydrogel conjugated with tetrakis(4-aminophenyl)porphyrin (NH2-TPP) and 2,4,6-tris(p...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Belali S,Karimi AR,Hadizadeh M

    更新日期:2018-04-15 00:00:00

  • Identification and characterization of a polysaccharide from the roots of Morinda officinalis, as an inducer of bone formation by up-regulation of target gene expression.

    abstract::Morinda officinalis is an important traditional tonic herbal medicine. In the present study, we found that crude polysaccharides extracted from M. officinalis, named MO90, could significantly increase the bone mineral density (BMD) of the whole femur, distal femur, and proximal femur in ovariectomized (OVX) rats. In a...

    journal_title:International journal of biological macromolecules

    pub_type: 杂志文章


    authors: Yan C,Huang D,Shen X,Qin N,Jiang K,Zhang D,Zhang Q

    更新日期:2019-07-15 00:00:00