当前位置： SCI文献检索 > INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES期刊下所有文献 > Identifying protein-protein interfacial residues in heterocomplexes using residue conservation scores.

Identifying protein-protein interfacial residues in heterocomplexes using residue conservation scores.

Abstract：

:Identifying protein-protein interfaces is crucial for structural biology. Because of the constraints in wet experiments, many computational methods have been proposed. Without knowing any information about the partner chains, a new method of predicting protein-protein interaction interface residues purely based on evolutionary information in heterocomplexes is proposed here. Unlike traditional approaches using multiple sequence alignment profiles to represent the conservation level for each residue, we make predictions based on the concept of residue conservation scores so that the dimension of the feature vector for each residue can be drastically reduced, at least 20 times less than conventional methods. Based on the representation approach, a simple linear discriminant function is used to make predictions, so the computational complexity of the whole prediction procedure can also be greatly decreased. By testing our approach on 69 heterocomplex chains, experimental results demonstrate the performance of our approach is indeed superior to current existing methods.

journal_name

Int J Biol Macromol

journal_title

International journal of biological macromolecules

authors

Li JJ,Huang DS,Wang B,Chen P

doi

10.1016/j.ijbiomac.2006.02.024

subject

Has Abstract

pub_date

2006-05-30 00:00:00

pages

241-7

issue

3-5

eissn

0141-8130

issn

1879-0003

pii

S0141-8130(06)00083-3

journal_volume

38

pub_type

杂志文章

相关文献

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES文献大全
  • Fabrication of pure chitosan nanofibrous membranes as effective absorbent for dye removal.

    abstract：:The pure chitosan nanofibrous membranes with average fiber diameter of 86±18, 114±17,164±28nm were successfully prepared by electrospinning. Batch adsorption experiments of using chitosan nanofibrous membranes as adsorbent to remove acid blue-113 were conducted. The adsorption capacity of 1377mg/g was achieved by the ...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2017.08.072

    authors： Li C,Lou T,Yan X,Long YZ,Cui G,Wang X

    更新日期：2018-01-01 00:00:00

  • Cu2+, Ca2+, and methionine oxidation expose the hydrophobic α-synuclein NAC domain.

    abstract：:α-Synuclein is an intrinsically disordered protein whose aggregation is related to Parkinson's disease and other neurodegenerative disorders. Metal cations are one of the main factors affecting the propensity of α-synuclein to aggregate, either by directly binding to it or by catalyzing the production of reactive oxyg...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2020.12.018

    authors： Ramis R,Ortega-Castro J,Vilanova B,Adrover M,Frau J

    更新日期：2021-02-01 00:00:00

  • Activation and stabilization of Candida antarctica lipase B in choline chloride-glycerol-water binary system via tailoring the hydrogen-bonding interaction.

    abstract：:As a new generation of green solvent, the utilization of natural deep eutectic solvents (NADESs) in enzymatic reactions has attracted widespread academic and industrial interests. Especially, choline chloride-glycerol (C-Gly) has been extensively used in many green chemistry processes. In this study, a series of C-Gly...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2019.06.150

    authors： Nian B,Cao C,Liu Y

    更新日期：2019-09-01 00:00:00

  • Adsorptive removal of Congo red from aqueous solutions using crosslinked chitosan and crosslinked chitosan immobilized bentonite.

    abstract：:Batch experiments were executed to investigate the removal of Congo red (CR) from aqueous solutions using the crosslinked chitosan (CCS) and crosslinked chitosan immobilized bentonite (CCS/BT composite). The CCS and CCS/BT composite were characterized by X-ray diffraction (XRD) and Fourier transform infrared spectrosc...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2016.01.083

    authors： Huang R,Zhang L,Hu P,Wang J

    更新日期：2016-05-01 00:00:00

  • Roles of amino acid residues H66 and D326 in the creatine kinase activity and structural stability.

    abstract：:Creatine kinase (CK) is a key enzyme for cellular energy metabolism, catalyzing the reversible phosphoryl transfer from phosphocreatine to ADP in vertebrates. CK contains a pair of highly conserved amino acids (H66 and D326) which might play an important role in sustaining the compact structure of CK by linking its N-...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2017.09.020

    authors： Wu QY,Wei F,Zhu YY,Tong YX,Cao J,Zhou P,Li ZY,Zeng LY,Li F,Wang XY,Xu KL

    更新日期：2018-02-01 00:00:00

  • Insight into the role of integrated carbohydrate polymers (starch, chitosan, and β-cyclodextrin) with mesoporous silica as carriers for ibuprofen drug; equilibrium and pharmacokinetic properties.

    abstract：:Three types of carbohydrate polymers starch (ST), chitosan (CH), and β-cyclodextrin (β-CD) were integrated with mesoporous silica (MCM-48) in some biopolymers nanocomposites (MCM-48/ST, MCM-48/CH, MCM-48/β-CD) as promising delivery systems for ibuprofen drug. This was conducted by simple mixing of the polymers gels wi...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2020.04.052

    authors： Abukhadra MR,Refay NM,Nadeem A,El-Sherbeeny AM,Ibrahim KE

    更新日期：2020-08-01 00:00:00

  • Incorporating allylated lignin-derivatives in thiol-ene gel-polymer electrolytes.

    abstract：:Growing environmental and economic concerns as well as the uncertainty that accompanies finite petrochemical resources contributes to the increase in research and development of bio-based, renewable polymers. Concurrently, industrial and consumer demand for smaller, safer, and more flexible technologies motivates a gl...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2018.02.160

    authors： Baroncini EA,Stanzione JF 3rd

    更新日期：2018-07-01 00:00:00

  • Injectable thermosensitive hybrid hydrogel containing graphene oxide and chitosan as dental pulp stem cells scaffold for bone tissue engineering.

    abstract：:Here, we fabricated thermosensitive injectable hydrogel containing poly (N-isopropylacrylamide) (PNIPAAm)-based copolymer/graphene oxide (GO) composite with different feed ratio to chitosan (CS) as a natural polymer through physical and chemical crosslinking for the proliferation and differentiation of the human denta...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2020.06.138

    authors： Amiryaghoubi N,Noroozi Pesyan N,Fathi M,Omidi Y

    更新日期：2020-11-01 00:00:00

  • Hydrophobic starch nanocrystals preparations through crosslinking modification using citric acid.

    abstract：:Biodegradable starch nanocrystals prepared by an acid treatment process were modified through crosslinking modification using citric acid as reactant by a dry reaction method. The occurrence of crosslinking modification was evaluated by Fourier transform infrared spectroscopy and swelling degree. X-ray diffraction, we...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2016.06.082

    authors： Zhou J,Tong J,Su X,Ren L

    更新日期：2016-10-01 00:00:00

  • Down-regulated miR-187 promotes oxidative stress-induced retinal cell apoptosis through P2X7 receptor.

    abstract：:Several microRNAs (miRNAs) expressed in the retina were confirmed to involve in retinal cell apoptosis, which was closely linked with the development of retinal diseases. Our previous studies have confirmed a vital role of miR-187 in retinal cells apoptosis. The aim of this study was to further elucidate the precise r...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2018.08.166

    authors： Zhang QL,Wang W,Alatantuya,Dongmei,Lu ZJ,Li LL,Zhang TZ

    更新日期：2018-12-01 00:00:00

  • Dielectric studies of proton transport in air-dried fully calcified and decalcified bone.

    abstract：:Measurements of dielectric properties of calcified and decalcified bone were made in the electric field frequency range of 10(1)-10(5) Hz and at temperatures from 22 to 250 degrees C. The temperature dependencies of the complex dielectric constant of bone revealed two main molecular processes. The first process corres...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/0141-8130(95)01052-1

    authors： Marzec E,Kubisz L,Jaroszyk F

    更新日期：1996-02-01 00:00:00

  • Fish collagen/alginate/chitooligosaccharides integrated scaffold for skin tissue regeneration application.

    abstract：:An emerging paradigm in wound healing techniques is that a tissue-engineered skin substitute offers an alternative approach to create functional skin tissue. Here we developed a fish collagen/alginate (FCA) sponge scaffold that was functionalized by different molecular weights of chitooligosaccharides (COSs) with the ...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2015.08.038

    authors： Chandika P,Ko SC,Oh GW,Heo SY,Nguyen VT,Jeon YJ,Lee B,Jang CH,Kim G,Park WS,Chang W,Choi IW,Jung WK

    更新日期：2015-11-01 00:00:00

  • Preparation and characterization of pH-responsive guar gum microspheres.

    abstract：:Guar gum, being the natural polymer is renewable, nontoxic, biocompatible and biodegradable. Therefore, it is the perfect material to formulate particulates or microspheres for potential applications in pharmaceutical. The formulation of material in nano/microsphere scale offers new rich in application potential. In v...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2013.09.045

    authors： Sharma S,Kaur J,Sharma G,Thakur KK,Chauhan GS,Chauhan K

    更新日期：2013-11-01 00:00:00

  • Macromolecular agents with antimicrobial potentialities: A drive to combat antimicrobial resistance.

    abstract：:In recent years, the antimicrobial resistance (AMR) or multidrug resistance (MDR) has become a serious health concern and major challenging issue, worldwide. After decades of negligence, the AMR has now captured global attention. The increasing number of antibiotic-resistant strains has threatened the achievements of ...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章,评审

    doi：10.1016/j.ijbiomac.2017.05.071

    authors： Bilal M,Rasheed T,Iqbal HMN,Hu H,Wang W,Zhang X

    更新日期：2017-10-01 00:00:00

  • Sequestration of toxic congo red dye from aqueous solution using ecofriendly guar gum/ activated carbon nanocomposite.

    abstract：:In the present study, a potential Guar gum/activated carbon nanocomposite as an adsorbent was synthesized and utilized for the sequestration of toxic congo red dye from synthetic wastewater. The nanocomposite was characterized using different techniques such as SEM, EDX, TEM, FTIR and XRD. Various physico-chemical par...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2020.05.025

    authors： Gupta VK,Agarwal S,Ahmad R,Mirza A,Mittal J

    更新日期：2020-05-07 00:00:00

  • Glycation of α-synuclein amplifies the binding with glyceraldehyde-3-phosphate dehydrogenase.

    abstract：:α-Synuclein was recently found to interact with moonlighting glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH) involved in neurodegenerative diseases development. In the present work, we have analyzed influence of α-synuclein glycation on this interaction, because the literature data suggest relation ...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2019.01.064

    authors： Semenyuk P,Barinova K,Muronetz V

    更新日期：2019-04-15 00:00:00

  • BmajPLA2-II, a basic Lys49-phospholipase A2 homologue from Bothrops marajoensis snake venom with parasiticidal potential.

    abstract：:Snake venoms contain various proteins, especially phospholipases A2 (PLA2s), which present potential applications in diverse areas of health and medicine. In this study, a new basic PLA2 from Bothrops marajoensis with parasiticidal activity was purified and characterized biochemically and biologically. B. marajoensis ...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2017.04.013

    authors： Grabner AN,Alfonso J,Kayano AM,Moreira-Dill LS,Dos Santos APA,Caldeira CAS,Sobrinho JC,Gómez A,Grabner FP,Cardoso FF,Zuliani JP,Fontes MRM,Pimenta DC,Gómez CV,Teles CBG,Soares AM,Calderon LA

    更新日期：2017-09-01 00:00:00

  • A comparison of eugenol and menthol on encapsulation characteristics with water-soluble quaternized β-cyclodextrin grafted chitosan.

    abstract：:Two guest molecules (eugenol and (-)-menthol) were investigated on inclusion complex formation with water-soluble quaternized β-CD grafted with chitosan (QCD-g-CS). The inclusion complexes were prepared at varying mole ratios between eugenol or (-)-menthol and β-CD (substituted on QCD-g-CS) by a conventional shaking m...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2015.11.006

    authors： Phunpee S,Saesoo S,Sramala I,Jarussophon S,Sajomsang W,Puttipipatkhachorn S,Soottitantawat A,Ruktanonchai UR

    更新日期：2016-03-01 00:00:00

  • Purification and characterization of a heterodimeric mycelial lectin from Penicillium proteolyticum with potent mitogenic activity.

    abstract：:In the present study, Penicillium proteolyticum lectin was purified by DEAE-Sepharose chromatography followed by Sephadex G-100 gel filtration chromatography. A sequence of ion-exchange and gel filtration chromatography resulted in 52.30 fold purified lectin with a high yield of 84.21%. The purified P. proteolyticum l...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2019.01.103

    authors： Singh RS,Walia AK,Kennedy JF

    更新日期：2019-05-01 00:00:00

  • Protein phosphatase inhibitor-1 (PPI-1) has protective activities in stress conditions in E. coli.

    abstract：:Protein phosphatase inhibitor-1 (PPI-1) is a major inhibitor of protein phosphatase 1 (PP1), which regulates signal transduction in many eukaryotic cellular processes. Biophysical studies have shown that PPI-1 has a large Stokes radius and is heat stable, suggesting that it lacks extensive secondary structures. The un...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2006.01.001

    authors： Kim TD

    更新日期：2006-02-28 00:00:00

  • Characterization, optimization and stability studies on Candida rugosa lipase supported on nanocellulose reinforced chitosan prepared from oil palm biomass.

    abstract：:The contribution of chitosan/nanocellulose (CS-NC) to the enzymatic activity of Candida rugosa lipase covalently bound on the surface of CS-NC (CRL/CS-NC) was investigated. Cellulosic material from oil palm frond leaves (OPFL) were bleached, alkaline treated and acid hydrolyzed to obtain the purified NC and used as na...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2018.03.095

    authors： Elias N,Chandren S,Razak FIA,Jamalis J,Widodo N,Wahab RA

    更新日期：2018-07-15 00:00:00

  • Structural characterization and anticomplement activity of an acidic polysaccharide from Hedyotis diffusa.

    abstract：:An acidic homogeneous polysaccharide (HD-PS-1) was purified from Hedyotis diffusa (Willd.) Roxb. HD-PS-1 possessed a backbone chain of →[4)-β-Glcp-3-OAc-(1]6→[6)-β-Manp-(1]2→6)-α-Galp-(1→[4)-α-Galp-(1]2→, with three branches of β-Manp-(1→3)-β-GlcpA, α-Rhap-(1→3)-α-Rhap and α-Galp attached to the backbone chain at O-4 ...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2019.11.132

    authors： Huo J,Lu Y,Jiao Y,Chen D

    更新日期：2020-07-15 00:00:00

  • Zn2+-loaded TOBC nanofiber-reinforced biomimetic calcium alginate hydrogel for antibacterial wound dressing.

    abstract：:Calcium alginate hydrogel dressing is an excellent hydrogel dressing because of its excellent absorption characteristics and tear-free pain. However, its application is limited by its poor mechanical properties and non-bacterial properties. Here, we reported a new biomimetic hydrogel dressing with good mechanical prop...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2019.12.046

    authors： Zhang M,Chen S,Zhong L,Wang B,Wang H,Hong F

    更新日期：2020-01-15 00:00:00

  • Binding behaviors and kinetics studies on the interaction of silver nanoparticles with trypsin.

    abstract：:The interaction of nanoparticles (NPs) with proteins is a topic of high relevance for the medical application of nanomaterials. In this study, a comprehensive investigation was performed to clarify the binding mechanism, adsorption isotherms and kinetics of the interaction between silver nanoparticles (AgNPs) and tryp...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2018.03.172

    authors： Li X,Yan Y,Cheng X,Guo W,Peng Y

    更新日期：2018-07-15 00:00:00

  • Structural characterization of arabinogalactan extracted from Ixeris chinensis (Thunb.) Nakai and its immunomodulatory effect on RAW264.7 macrophages.

    abstract：:An arabinogalactan (ICPA) was isolated from the water extract of Ixeris chinensis (Thunb.) Nakai. ICPA was mainly composed of galactose and arabinose with minor amount of glucose. The molecular weight of ICPA was 58.1 kDa. Structural analysis by methylation and NMR spectroscopy indicated that ICPA contained α-D-Glcp(1...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2019.09.158

    authors： Li H,Xie W,Qiao X,Cui H,Yang X,Xue C

    更新日期：2020-01-15 00:00:00

  • Computational study of the conformational profiles of model bis-cystine cyclic peptides.

    abstract：:Bis-cystine cyclic peptides are a new kind of molecules with potential use as cavitands, transporters or antagonists of target ligands. Studies aimed at establishing their conformational profiles may prove useful in understanding their characteristics and potentiate their use in molecular design. The present investiga...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/0141-8130(95)01083-1

    authors： Fernandez Y,Ricart JM,Perez JJ

    更新日期：1996-06-01 00:00:00

  • Sugar compositions, α-glucosidase inhibitory and amylase inhibitory activities of polysaccharides from leaves and flowers of Camellia sinensis obtained by different extraction methods.

    abstract：:The sugar compositions, α-glucosidase inhibitory and α-amylase inhibitory activities of polysaccharides from leaves and flowers of green tea (Camellia sinensis) obtained by hot water extraction (HWE), boiled water extraction (BWE) and enzymatic extraction (EE) were investigated. The yields, sugar contents and monosacc...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2010.07.007

    authors： Wang Y,Yang Z,Wei X

    更新日期：2010-11-01 00:00:00

  • Effect of diameter of poly(lactic acid) fiber on the physical properties of poly(ɛ-caprolactone).

    abstract：:Biodegradable polymer composites based on poly(ɛ-caprolactone) (PCL) and poly(lactic acid) (PLA) fibers with diameters of 18, 26, 180 μm were prepared by melt compounding. The PLA fiber content in the composites was constant at 20% by weight. The effects of fibers with different diameters on the physical properties an...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2015.01.059

    authors： Ju D,Han L,Guo Z,Bian J,Li F,Chen S,Dong L

    更新日期：2015-05-01 00:00:00

  • Sulfated modification of the polysaccharides from Crassostrea gigas and their antioxidant and hepatoprotective activities through metabolomics analysis.

    abstract：:Sulfated polysaccharides from Crassostrea gigas (SCGP) were successfully prepared using chlorosulfonic acid-pyridine method. The structure of SCGP was determined by high performance liquid chromatography (HPLC), Fourier transform infrared spectrometry (FT-IR) and nuclear magnetic resonance (NMR). The results of spectr...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2019.02.053

    authors： Zhao G,Zhai X,Qu M,Tong C,Li W

    更新日期：2019-05-15 00:00:00

  • The effect of aluminum oxide on red blood cell integrity and hemoglobin structure at nanoscale.

    abstract：:Herein, we explored the interaction of Al2O3 NPs with RBCs and Hb to determine the effect of Al2O3 NPs on hemolytic activity and Hb denaturation. The percentage of hemolysis of extracts and direct contact assays triggered by Al2O3 NPs was calculated by determining supernatant Hb concentration at 540 nm. Far-UV CD and ...

    journal_title：International journal of biological macromolecules

    pub_type： 杂志文章

    doi：10.1016/j.ijbiomac.2019.07.154

    authors： Kahbasi S,Samadbin M,Attar F,Heshmati M,Danaei D,Rasti B,Salihi A,Nanakali NMQ,Aziz FM,Akhtari K,Hasan A,Falahati M

    更新日期：2019-10-01 00:00:00