Circular RNAs: from biogenesis and function to diseases.

abstract：BACKGROUND:The second-trimester maternal serum screening in twin pregnancy is still controversial, as the serum marker levels in twins are not as clear as those in singletons. This study aimed to evaluate the relationship between the levels of the second-trimester maternal serum free beta-human chorionic gonadotropin (...

journal_title：Chinese medical journal

authors： Zheng MM,Hu YL,Zhang CY,Ru T,Liu QL,Xu BY,Chen QG,Xu ZF,Zhang Y,Zhong XL

更新日期：2010-03-05 00:00:00

abstract：OBJECTIVE:To observe the long-term follow-up of 72 patients with transient ischemic attack (TIA) and evaluate the clinical significance of neurovascular surgical indication. METHODS:Seventy-two patients with TIA collected from years 1959 to 1977 were followed up by means of face-to-face communication with the patients...

journal_title：Chinese medical journal

authors： Gong T,Wang X

更新日期：2001-12-01 00:00:00

abstract：:Osteoarthritis (OA) models in bipedal rats were used to study the immune response, including the changes of IgG, antibody dependent cytotoxicity tests toward articular chondrocytes and the matrix. The results revealed significant difference between the bipedal and the quadruped rats. Immunological studies have proved ...

journal_title：Chinese medical journal

authors： Chen YP,Yang Y,Chen BX

更新日期：1991-03-01 00:00:00

abstract：:A case of cutaneous Rosai-Dorfman disease (CRDD) presenting as a granulomatous rosacea-like rashs was reported. A 45-year-old Chinese woman presented with a 1-month history of a widespread nonpruiginous papulonodular eruption. The rash had begun on her face and rapidly progressed to involve the neck and extremities. S...

journal_title：Chinese medical journal

authors： Shi XY,Ma DL,Fang K

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:The endovascular treatment of abdominal aortic aneurysm (AAA) has improved greatly in the last 15 years. The present study aimed to evaluate the endografting experience for the treatment of unfavorable abdominal aortic aneurysm (uAAA). METHODS:During December 2001 and December 2007, 41 patients with uAAA we...

journal_title：Chinese medical journal

authors： Hu ZJ,Chang GQ,Li XX,Huang XL,Yin HH,Wang SM

更新日期：2009-04-05 00:00:00

abstract：:Atriopeptin III (AP III) and its six analogues were synthesized by solid phase method and their diuretic and hypotensive activities were determined. Among these analogues, analogue [D-Ala-5, D-Arg-23] AP III was nearly 10 times as potent as AP III in diuretic activity while its hypotensive activity increased only 50% ...

journal_title：Chinese medical journal

authors： Wang J,Shi P

更新日期：1995-04-01 00:00:00

abstract：BACKGROUND:In central precocious puberty (CPP), the pulse secretion and release of gonadotropin-releasing hormone (GnRH) are increased due to early activation of the hypothalamic-pituitary-gonadal axis, resulting in developmental abnormalities with gonadal development and appearance of secondary sexual characteristics....

journal_title：Chinese medical journal

authors： Li WJ,Gong CX,Guo MJ,Xing J,Li T,Song WH,Luo XP,Wu D,Liang JP,Cao BY,Gu Y,Su C,Liang XJ,Liu M,Wang R,Li FT

更新日期：2015-05-20 00:00:00

abstract：BACKGROUND:Hospital-acquired pneumonia (HAP) is the most common hospital-acquired infection in China with substantial morbidity and mortality. But no specific risk assessment model has been well validated in patients with HAP. The aim of this study was to investigate the published risk assessment models that could pote...

journal_title：Chinese medical journal

authors： Wen JN,Li N,Guo CX,Shen N,He B

更新日期：2020-12-03 00:00:00

abstract：BACKGROUND:Human epididymis secretory protein 4 (HE4) is a new ovarian cancer biomarker. The factors influencing HE4 levels are not clear, and the reference data in China are limited. Here, we aim to evaluate the effects of menopause and age on HE4 levels and to provide a possible reference value for HE4 in healthy Chi...

journal_title：Chinese medical journal

authors： Cheng HY,Zeng L,Ye X,Ma RQ,Tang ZJ,Chu HL,Zhao YM,Zhu LR,Gao YN,Chang XH,Cui H

更新日期：2020-06-05 00:00:00

abstract：Background:Myoclonic epilepsy with ragged red fibers (MERRF) syndrome is characterized by myoclonus, generalized epilepsy, cerebellar ataxia, and ragged red fibers (RRFs) in the muscle. T-to-C transition at nucleotide position 14709 in the mitochondrial tRNA glutamic acid (tRNAGlu) gene has previously been associated w...

journal_title：Chinese medical journal

authors： Ban R,Guo JH,Pu CQ,Shi Q,Liu HX,Zhang YT

更新日期：2018-07-05 00:00:00

abstract：BACKGROUND:The 2019 novel coronavirus has caused the outbreak of the acute respiratory disease in Wuhan, Hubei Province of China since December 2019. This study was performed to analyze the clinical characteristics of patients who succumbed to and who recovered from 2019 novel coronavirus disease (COVID-19). METHODS:C...

journal_title：Chinese medical journal

authors： Deng Y,Liu W,Liu K,Fang YY,Shang J,Zhou L,Wang K,Leng F,Wei S,Chen L,Liu HG

更新日期：2020-06-05 00:00:00

abstract：BACKGROUND:Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) are X-linked recessive neuromuscular diseases resulting from dystrophin (DMD) gene mutations. It has been known that the carrier of DMD mutations may also have symptoms of the disease. While de novo mutation is quite common in BMD/DMD pati...

journal_title：Chinese medical journal

authors： Yu H,Chen YC,Liu GL,Wu ZY

更新日期：2017-10-05 00:00:00

abstract：BACKGROUND:Atrial natriuretic peptide (ANP) and its natriuretic peptide receptors A (NPR-A) and C (NPR-C) are involved in the regulation of physiological and pathophysiological process of blood pressure. The present study aimed to determine the role of NPR-C in the development of salt-sensitive hypertension. METHODS:T...

journal_title：Chinese medical journal

authors： Zhu XL,Zhang T,Xu ZQ,Ma XC,Wang ZJ,Zou CW,Li JX,Jing HY

更新日期：2020-05-20 00:00:00

abstract：OBJECTIVE:To investigate whether pretreatment with repeated electroacupuncture (EA) at the Baihui acupoint could induce ischemic tolerance against transient focal cerebral ischemic injury in rats. METHODS:Thirty male Sprague-Dawley (SD) rats were randomly divided into 3 groups (n=10 for each): the control group consis...

journal_title：Chinese medical journal

authors： Xiong L,Lu Z,Hou L,Zheng H,Zhu Z,Wang Q,Chen S

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Acute kidney injury (AKI) is a severe disease in critically ill patients. Neutrophil infiltration into kidney was associated with the development of AKI, and P-selectin may be involved in the process of neutrophil recruitment in kidney. This study aimed to explore the potential effect of platelet-derived P-s...

journal_title：Chinese medical journal

authors： Li XH,Qian YB,Meng XX,Wang RL

更新日期：2017-07-20 00:00:00

abstract：OBJECTIVE:To study the surgical technique and results of laryngeal function preservation in treatment of hypopharyngeal carcinoma. METHODS:A retrospective review of 305 patients with malignant neoplasms of the hypopharynx (279 males, 26 females, age ranging from 14 to 77 years) was performed from 1978 to 1996. In the ...

journal_title：Chinese medical journal

authors： Wang T,Li X,Lu Y,Yu Z

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:Intravertebral and general anesthesia (GA) are two main anesthesia approaches but both have defects. This study was aimed to evaluate the effect of subarachnoid anesthesia combined with propofol target-controlled infusion (TCI) on blood loss and transfusion for total hip arthroplasty (THA) in elderly patient...

journal_title：Chinese medical journal

authors： Xu CS,Qu XD,Qu ZJ,Wang G,Wang HJ

更新日期：2020-03-20 00:00:00

abstract：BACKGROUND:Carotid stenosis is one of the common reasons for patients with ischemic stroke, and the two invasive options carotid endarterectomy (CEA) and carotid artery stenting (CAS) are the most popular treatments. But the relative efficacy and safety of the methods are not clear. METHODS:About 521 articles related ...

journal_title：Chinese medical journal

authors： Wang L,Liu XZ,Liu ZL,Lan FM,Shi WC,Liu J,Zhang JN

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVE:To study the histopathological changes of relevant internal organs of Macaca mulatta infected with Plasmodium knowlesi (P. knowlesi). METHODS:Histopathological examination of 3 monkeys who died of P. knowlesi infection, 2 P. knowlesi infected monkeys who died of treatment failure with artesunate suppository ...

journal_title：Chinese medical journal

authors： Chen L,Li G,Lu Y,Luo Z

更新日期：2001-10-01 00:00:00

abstract：OBJECTIVE:To investigate the regulation effect of protein kinase ERK on the activation of transcription factor STAT3 in response to IL-6 in the Sko-007 human myeloma cell line. METHODS:Electrophoretic mobility shift assay (EMSA) and immunoprecipitation (IP) were used to show the activation of STAT3 and ERK in Sko-007 ...

journal_title：Chinese medical journal

authors： Song L,Shen B,Li Y

更新日期：2001-09-01 00:00:00

abstract：Objective:Mechanical ventilation (MV) has long been used as a life-sustaining approach for several decades. However, researchers realized that MV not only brings benefits to patients but also cause lung injury if used improperly, which is termed as ventilator-induced lung injury (VILI). This review aimed to discuss the...

journal_title：Chinese medical journal

authors： Chen L,Xia HF,Shang Y,Yao SL

更新日期：2018-05-20 00:00:00

abstract：OBJECTIVE:Hypertension is an important risk factor of cardiovascular disease and increases mortality in the elderly. However, the available medical evidences are both inconsistent and insufficient regarding establishing credible and useful blood pressure (BP) targets in the hypertensive elderly. This review summarizes ...

journal_title：Chinese medical journal

authors： Liu P,Zheng JG

更新日期：2017-08-20 00:00:00

abstract：BACKGROUND:In patients with chronic total occlusion (CTO) and multivessel coronary artery disease, the comparison of surgical and the percutaneous revascularization strategies has rarely been conducted. The aim of this study was to compare long term clinical outcomes of drug eluting stent (DES) implantation with corona...

journal_title：Chinese medical journal

authors： Liu W,Ma CS,Kang JP,Du X,Chen F,Zhou YJ,Lü SZ,Huang FJ,Gu CX,Zhu XL

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Bioactive proteins, such as cytokines and chemokines, have not been systematically evaluated in healthy and preeclamptic pregnancies. We aimed to investigate the difference of these proteins between healthy and preeclamptic pregnancies in order to help clarify their potential roles in the pathogenesis of hyp...

journal_title：Chinese medical journal

authors： Wang T,Wang YY,Zhou R,Song CP,Lin W,Niu XY,Zhang L,Hu HZ

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:The dyschromatoses are a group of disorders characterized by simultaneous hyperpigmented macules together with hypopigmented macules. Dyschromatosis universalis hereditaria (DUH) and dyschromatosis symmetrica hereditaria are two major types. While clinical and histological presentations are similar in these ...

journal_title：Chinese medical journal

authors： Liu JW,Asan.,Sun J,Vano-Galvan S,Liu FX,Wei XX,Ma DL

更新日期：2016-01-05 00:00:00

abstract：:A 30-year-old female patient with coexisting ankylosing spondylitis and rheumatoid arthritis was diagnosed and treated. The human leukocyte antigen (HLA)-B27 is a predisposing factor of ankylosing spondylitis and HLA-DR4 is a predisposing factor of rheumatoid arthritis. This patient was HLA-B27 and HLA-DR4 positive, a...

journal_title：Chinese medical journal

authors： Guo YY,Yang LL,Cui HD,Zhao S,Zhang N

更新日期：2011-10-01 00:00:00

abstract：:Ninety-five patients with perforation, hemorrhage or stenosis due to duodenal ulcer were treated by extended parietal cell vagotomy. Postoperative follow-up ranged from 3.5 to 10 years (mean 6 years) in 88 patients (92%) with acute perforation (60), hemorrhage (8) and stenosis (20). There was no operative mortality. U...

journal_title：Chinese medical journal

authors： Li SY,An P,Liang ZJ,Yuan SJ,Yu J

更新日期：1992-04-01 00:00:00

abstract：BACKGROUND:The Xpert MTB/RIF showed high sensitivity and specificity in previous studies carried out in different epidemiological and geographical settings and patient populations in high-burden tuberculosis (TB) countries. However, there were little data obtained by validation or demonstration study of the assay in Ch...

journal_title：Chinese medical journal

authors： Hu P,Bai L,Liu F,Ou X,Zhang Z,Yi S,Chen Z,Gong D,Liu B,Guo J,Tan Y

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Although a variety of risk factors of pneumonia after clipping or coiling of the aneurysm (post-operative pneumonia [POP]) in patients with aneurysmal subarachnoid hemorrhage (aSAH) have been studied, the predictive model of POP after aSAH has still not been well established. Thus, the aim of this study was ...

journal_title：Chinese medical journal

authors： Chen Y,Lian BQ,Peng L,Ding CY,Lin YX,Yu LH,Wang DL,Kang DZ

更新日期：2020-12-24 00:00:00

abstract：BACKGROUND:Fluid dynamic mechanisms attributed to coronary bifurcation lesions remain a subject of study. The present study aimed at investigating the hemodynamic change of wall shear stress (WSS) in patients with coronary bifurcation lesions treated by double kissing (DK) crush or one-stent with final kissing balloon ...

journal_title：Chinese medical journal

authors： Chen SL,Kan J,Zhang JJ,Hu ZY,Xu T

更新日期：2012-05-01 00:00:00