Expression of ZNF695 Transcript Variants in Childhood B-Cell Acute Lymphoblastic Leukemia.

abstract：:Colorectal cancer is the fourth most common neoplasia in Europe, where it accounts for 28.2 new cases per 100,000 inhabitants. In an effort to decrease the incidence of this disease, various prevention measures are being studied, one of which are anthocyanin-rich foods. Anthocyanins are potent antioxidant flavonoids m...

journal_title：Genes

authors： Fernández J,García L,Monte J,Villar CJ,Lombó F

更新日期：2018-03-01 00:00:00

abstract：:Drosophila melanogaster is one of the most extensively used genetic model organisms for studying LTR retrotransposons that are represented by various groups in its genome. However, the phenomenon of molecular domestication of LTR retrotransposons has been insufficiently studied in Drosophila, as well as in other inver...

journal_title：Genes

authors： Makhnovskii P,Balakireva Y,Nefedova L,Lavrenov A,Kuzmin I,Kim A

更新日期：2020-04-06 00:00:00

abstract：:RNA plays complex roles in normal health and disease and is becoming an important target for therapeutic intervention; accordingly, therapeutic strategies that modulate RNA function have gained great interest over the past decade. Antisense oligonucleotides (AOs) are perhaps the most promising strategy to modulate RNA...

journal_title：Genes

authors： Imbert M,Dias-Florencio G,Goyenvalle A

更新日期：2017-01-26 00:00:00

abstract：:The Muraenidae is one of the largest and most complex anguilliform families. Despite their abundance and important ecological roles, morays are little studied, especially cytogenetically, and both their phylogenetic relationships and the taxonomy of their genera are controversial. With the aim of extending the karyolo...

journal_title：Genes

authors： Coluccia E,Deidda F,Lobina C,Melis R,Porcu C,Agus B,Salvadori S

更新日期：2020-11-06 00:00:00

abstract：BACKGROUND:Radiation induces DNA double-strand breaks (DSBs), and chromosome aberrations (CA) form during the DSBs repair process. Several methods have been used to model the repair kinetics of DSBs including the bi-exponential model, i.e., N(t) = N1exp(-t/τ1) + N2exp(-t/τ2), where N(t) is the number of breaks at time ...

journal_title：Genes

authors： Plante I,Slaba T,Shavers Z,Hada M

更新日期：2019-11-16 00:00:00

abstract：:Genetic variations introduced via introgression from Western to Chinese pigs have contributed to the performance of Chinese breeds in traits such as growth rate and feed conversion efficiency. However, little is known about the underlying genomic changes that occurred during introgression and the types of traits affec...

journal_title：Genes

authors： Wang J,Liu C,Chen J,Bai Y,Wang K,Wang Y,Fang M

更新日期：2020-03-04 00:00:00

abstract：:Lactobacillus ruminis is a commensal motile lactic acid bacterium living in the intestinal tract of humans and animals. Although a few genomes of L. ruminis were published, most of them were animal derived. To explore the genetic diversity and potential niche-specific adaptation changes of L. ruminis, in the current w...

journal_title：Genes

authors： Wang S,Yang B,Ross RP,Stanton C,Zhao J,Zhang H,Chen W

更新日期：2020-01-08 00:00:00

abstract：:In this study, we aim to characterize the genetic environment of the plasmid-mediated colistin resistance gene mcr-1 in 25 Escherichia coli and seven Klebsiella pneumoniae strains from different countries and continents. Multilocus sequence typing, conjugation experiments, plasmid typing, and the presence and location...

journal_title：Genes

authors： Hadjadj L,Riziki T,Zhu Y,Li J,Diene SM,Rolain JM

更新日期：2017-12-19 00:00:00

abstract：:N6-methyladenosine (m6A) is the most abundant RNA modification. It has been involved in the regulation of RNA metabolism, including degradation and translation, in both physiological and disease conditions. A recent study showed that m6A-mediated degradation of key transcripts also plays a role in the control of T cel...

journal_title：Genes

authors： Furlan M,Galeota E,de Pretis S,Caselle M,Pelizzola M

更新日期：2019-01-08 00:00:00

abstract：:Plant tissue culture methods, such as somatic embryogenesis, are attractive alternatives to traditional breeding methods for plant propagation. However, they often suffer from limited efficiency. Somatic embryogenesis receptor kinase (SERK)1 is a marker gene of early somatic embryogenesis in several plants, including ...

journal_title：Genes

authors： Luan A,He Y,Xie T,Chen C,Mao Q,Wang X,Li C,Ding Y,Lin W,Liu C,Xia J,He J

更新日期：2019-11-01 00:00:00

abstract：:Illumina and nanopore sequencing technologies are powerful tools that can be used to determine the bacterial composition of complex microbial communities. In this study, we compared nasal microbiota results at genus level using both Illumina and nanopore 16S rRNA gene sequencing. We also monitored the progression of n...

journal_title：Genes

authors： Heikema AP,Horst-Kreft D,Boers SA,Jansen R,Hiltemann SD,de Koning W,Kraaij R,de Ridder MAJ,van Houten CB,Bont LJ,Stubbs AP,Hays JP

更新日期：2020-09-21 00:00:00

abstract：:Serotonin receptor 2A (HTR2A) is an important signalling factor implicated in cognitive functions and known to be associated with schizophrenia. The biological significance of HTR2A in schizophrenia remains unclear as molecular analyses including genetic association, mRNA expression and methylation studies have report...

journal_title：Genes

authors： Cheah SY,Lawford BR,Young RM,Morris CP,Voisey J

更新日期：2017-01-04 00:00:00

abstract：:Perennial agriculture has been proposed as an option to improve the sustainability of cropping systems, by increasing the efficiency of resource use, while also providing ecosystem services. Neo-domestication, the contemporary domestication of plants that have not previously been used in agriculture, can be used to ge...

journal_title：Genes

authors： Kantar MB,Hüber S,Herman A,Bock DG,Baute G,Betts K,Ott M,Brandvain Y,Wyse D,Stupar RM,Rieseberg LH

更新日期：2018-08-21 00:00:00

abstract：:During the evolution of heteromorphic sex chromosomes, the sex-specific Y chromosome degenerates, while the X chromosome evolves new mechanisms of regulation. Using bioinformatic and experimental approaches, we investigate the expression of the X chromosome in Drosophila melanogaster. We observe nearly complete X chro...

journal_title：Genes

authors： Argyridou E,Parsch J

更新日期：2018-05-04 00:00:00

abstract：:Sarcomas are highly aggressive cancers that have a high propensity for metastasis, fail to respond to conventional therapies, and carry a poor 5-year survival rate. This is particularly true for patients with neurofibromatosis type 1 (NF1), in which 8%-13% of affected individuals will develop a malignant peripheral ne...

journal_title：Genes

authors： Moon CI,Tompkins W,Wang Y,Godec A,Zhang X,Pipkorn P,Miller CA,Dehner C,Dahiya S,Hirbe AC

更新日期：2020-05-01 00:00:00

abstract：:Interleukin 8 (IL-8) participates in the immune response and has the function of inducing neutrophils to release lysosomal enzymes and eliminate pathogens. This study was to investigate the effect of single nucleotide mutations in the IL-8 gene promoter region on the coccidiosis resistance index. In this study, 180 in...

journal_title：Genes

authors： Wang XH,Yu HL,Zou WB,Mi CH,Dai GJ,Zhang T,Zhang GX,Xie KZ,Wang JY

更新日期：2020-04-27 00:00:00

abstract：:In contrast to the amazing exponential growth in knowledge related to long non-coding RNAs (lncRNAs) involved in cell homeostasis or dysregulated pathological states, little is known so far about the links between the chemical modifications occurring in lncRNAs and their function. Generally, ncRNAs are post-transcript...

journal_title：Genes

authors： Dinescu S,Ignat S,Lazar AD,Constantin C,Neagu M,Costache M

更新日期：2019-01-16 00:00:00

abstract：:Chlorella is a popular microalga with robust physiological and biochemical characteristics, which can be cultured under various conditions. The exploration of the small RNA content of Chlorella could improve strategies for the enhancement of metabolite production from this microalga. In this study, stress was introduc...

journal_title：Genes

authors： Azaman SNA,Satharasinghe DA,Tan SW,Nagao N,Yusoff FM,Yeap SK

更新日期：2020-09-25 00:00:00

abstract：:Animals have co-evolved with mutualistic microbial communities, known as the microbiota, which are essential for organ development and function. We hypothesize that modern animal husbandry practices exert an impact on the intestinal microbiota. In this study, we compared the structure of the fecal microbiota between f...

journal_title：Genes

authors： De Jesús-Laboy KM,Godoy-Vitorino F,Piceno YM,Tom LM,Pantoja-Feliciano IG,Rivera-Rivera MJ,Andersen GL,Domínguez-Bello MG

更新日期：2011-12-21 00:00:00

abstract：:Adiponectin plays an important role in energy homeostasis and metabolism in mammalian adipose tissue. In this study, the relationship between adiponectin gene (ADIPOQ) haplotypes and variation in growth and carcass traits in New Zealand (NZ) Romney lambs was investigated using General Linear Models (GLMs). Eight haplo...

journal_title：Genes

authors： An Q,Zhou H,Hu J,Luo Y,Hickford JGH

更新日期：2017-06-12 00:00:00

abstract：:Fragile X syndrome (FXS) is the most common inherited cause of intellectual disability and autism spectrum disorder, and among those with fragile X syndrome, approximately 1/3rd meet a threshold for an autism spectrum disorder (ASD) diagnosis. Previous functional imaging studies of fragile X syndrome have typically fo...

journal_title：Genes

authors： McKechanie AG,Campbell S,Eley SEA,Stanfield AC

更新日期：2019-12-17 00:00:00

abstract：:B chromosomes (Bs) were discovered a century ago, and since then, most studies have focused on describing their distribution and abundance using traditional cytogenetics. Only recently have attempts been made to understand their structure and evolution at the level of DNA sequence. Many questions regarding the origin,...

journal_title：Genes

authors： Clark FE,Conte MA,Kocher TD

更新日期：2018-12-05 00:00:00

abstract：:The revolution in next-generation DNA sequencing technologies is leading to explosive data growth in genomics, posing a significant challenge to the computing infrastructure and software algorithms for genomics analysis. Various big data technologies have been explored to scale up/out current bioinformatics solutions ...

journal_title：Genes

authors： Shi L,Wang Z

更新日期：2019-12-06 00:00:00

abstract：:Background: Congenital disorder of glycosylation (CDG) is a severe morphogenic and metabolic disorder that affects all of the systems of organs and is caused by a mutation of the gene PMM2, having a mortality rate of 20% during the first months of life. Results: Here we report the outcome of an in vitro fertilisation ...

journal_title：Genes

authors： Doroftei B,Nemtanu L,Ilie OD,Simionescu G,Ivanov I,Anton E,Puiu M,Maftei R

更新日期：2020-06-25 00:00:00

abstract：:Vavilovia formosa is a relict leguminous plant growing in hard-to-reach habitats in the rocky highlands of the Caucasus and Middle East, and it is considered as the putative closest living relative of the last common ancestor (LCA) of the Fabeae tribe. Symbionts of Vavilovia belonging to Rhizobium leguminosarum bv. vi...

journal_title：Genes

authors： Chirak ER,Kimeklis AK,Karasev ES,Kopat VV,Safronova VI,Belimov AA,Aksenova TS,Kabilov MR,Provorov NA,Andronov EE

更新日期：2019-12-01 00:00:00

abstract：:The transition from a dormant to a germinating seed represents a crucial developmental switch in the life cycle of a plant. Subsequent transition from a germinating seed to an autotrophic organism also requires a robust and multi-layered control. Seed germination and seedling growth are multistep processes, involving ...

journal_title：Genes

authors： Longo C,Holness S,De Angelis V,Lepri A,Occhigrossi S,Ruta V,Vittorioso P

更新日期：2020-12-31 00:00:00

abstract：:In forensics, mitochondrial DNA (mtDNA) analysis is foremost applied to rootless hairs often lacking detectable nuclear DNA. Sanger sequencing is the routine mtDNA method in most forensic laboratories, even though interpretation of mixed samples and heteroplasmic sites can be challenging. Individuals may hold cells wi...

journal_title：Genes

authors： Gaag KJV,Desmyter S,Smit S,Prieto L,Sijen T

更新日期：2020-11-16 00:00:00

abstract：:In this work, we have shown that Novosphingobium tardaugens NBRC 16725 (strain ARI-1), a bacterial strain that was isolated due to its capacity to mineralize the estrogenic endocrine compound 17β-estradiol, is also able to mineralize testosterone, the androgenic endocrine compound. Using in silico analysis, we predict...

journal_title：Genes

authors： Ibero J,Galán B,Díaz E,García JL

更新日期：2019-10-31 00:00:00

abstract：:Amazonian puffing snakes (Spilotes; Colubridae) are snakes widely distributed in the Neotropical region. However, chromosomal data are scarce in this group and, when available, are only limited to karyotype description using conventional staining. In this paper, we focused on the process of karyotype evolution and tre...

journal_title：Genes

authors： Viana PF,Ezaz T,de Bello Cioffi M,Jackson Almeida B,Feldberg E

更新日期：2019-04-09 00:00:00

abstract：:Despite the extensive research conducted in recent decades, the molecular mechanisms underlying major depressive disorder (MDD) and relative evidence-based treatments remain unclear. Various hypotheses have been successively proposed, involving different biological systems. This narrative review aims to critically ill...

journal_title：Genes

authors： Maffioletti E,Minelli A,Tardito D,Gennarelli M

更新日期：2020-09-18 00:00:00