Congenital diaphragmatic hernia-associated cardiac dysfunction.

Abstract:

:There is increasing evidence that cardiac dysfunction is a key contributor to CDH pathophysiology. Dysfunction in both right and left ventricles is common in the early neonatal period, contributes to clinical disease severity, and is associated with adverse outcomes including death and ECMO use. Early and routine assessment of ventricular function and pulmonary artery pressure may guide individualized clinical decision-making, including use of pulmonary vasodilators, cardiotropes, ECMO, and timing of surgical repair. Minimizing cardiac dysfunction, whether by prenatal, postnatal or perinatal treatment strategies, may lead to improved outcome in CDH.

journal_name

Semin Perinatol

journal_title

Seminars in perinatology

authors

Patel N,Massolo AC,Kipfmueller F

doi

10.1053/j.semperi.2019.07.007

subject

Has Abstract

pub_date

2020-02-01 00:00:00

pages

151168

issue

1

eissn

0146-0005

issn

1558-075X

pii

S0146-0005(19)30102-8

journal_volume

44

pub_type

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