Peri-viable birth: legal considerations.

abstract：:Unpublished results can bias biomedical literature, favoring positive over negative findings, primary over secondary analyses, and can lead to duplicate studies that unnecessarily endanger subjects and waste resources. The Neonatal Research Network's (NRN) publication policies for approving, reviewing, and tracking ab...

journal_title：Seminars in perinatology

authors： Archer SW,Carlo WA,Truog WE,Stevenson DK,Van Meurs KP,Sánchez PJ,Das A,Devaskar U,Nelin LD,Petrie Huitema CM,Crawford MM,Higgins RD,Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research

更新日期：2016-10-01 00:00:00

abstract：:The use of broad spectrum antimicrobials, the emergence of multiresistant organisms, and the hospital drug costs associated with antimicrobials have all driven the need for institutions to develop strategies to control the use of antimicrobials. Formulary restrictions, prior approval mechanisms, treatment guidelines, ...

journal_title：Seminars in perinatology

authors： Kubin CJ

更新日期：2002-10-01 00:00:00

abstract：:Surviving extremely low-birth-weight infants are at risk of severe neurodevelopmental disability. Transfusion with packed red cells is almost universal in the care of these infants, but the hemoglobin threshold at which these transfusions should be given is unclear. Different clinical trials of restrictive (low hemogl...

journal_title：Seminars in perinatology

authors： Whyte RK

更新日期：2012-08-01 00:00:00

abstract：:Bronchopulmonary dysplasia (BPD) is a chronic lung disease which develops as a result of neonatal/perinatal lung injury. It is the commonest cause of chronic lung disease in infancy and the most frequent morbidity associated with prematurity. The incidence of BPD has continued to rise despite many advances in neonatal...

journal_title：Seminars in perinatology

authors： Bhandari A,Panitch H

更新日期：2018-11-01 00:00:00

abstract：:Use of immunosuppressants during pregnancy is indicated for anti-rejection therapy in transplantation patients and treatment of autoimmune diseases. Maternal side effects include nephrotoxocity and hepatotoxicity. All immunosuppressant drugs cross the placenta. Immunosuppressant use during the first trimester is not s...

journal_title：Seminars in perinatology

authors： Little BB

更新日期：1997-04-01 00:00:00

abstract：:Poorly controlled maternal diabetes in pregnancy may delay fetal pulmonary maturation. However, diabetic women with good glycemic control have fetal lung maturation at the same gestational age as nondiabetic women. With modern ultrasound technology, gestational dates can be accurately assessed in the first or early se...

journal_title：Seminars in perinatology

authors： Piper JM

更新日期：2002-06-01 00:00:00

abstract：:STDs can be one of the most common antepartum complications in high-risk gravidas. Screening for gonorrhea, syphilis, HPV, and possibly hepatitis B and chlamydial infection, should be considered in most, if not all, pregnant women. Familiarity with the common clinical presentations and treatment of bacterial STDs will...

journal_title：Seminars in perinatology

authors： Wendel GD Jr

更新日期：1990-04-01 00:00:00

abstract：:Inhaled nitric oxide (iNO), a selective pulmonary vasodilator, is available for treatment of persistent pulmonary hypertension of the newborn in term and near-term neonates. iNO decreases pulmonary vascular resistance leading to diminished extrapulmonary shunt and also has a microselective effect which improves ventil...

journal_title：Seminars in perinatology

authors： Kinsella JP,Abman SH

更新日期：2000-12-01 00:00:00

abstract：:Traditionally, genetic testing has been too slow or perceived to be impractical to initial management of the critically ill neonate. Technological advances have led to the ability to sequence and interpret the entire genome of a neonate in as little as 26 h. As the cost and speed of testing decreases, the utility of w...

journal_title：Seminars in perinatology

authors： Petrikin JE,Willig LK,Smith LD,Kingsmore SF

更新日期：2015-12-01 00:00:00

abstract：:The many physiological and hormonal changes occurring during pregnancy have the potential to affect a woman's cardiovascular responses to aerobic exercise. For example, it seems that increased mass and dilation of the left ventricle allow maintenance of wall stress, ensuring adequate pumping function throughout gestat...

journal_title：Seminars in perinatology

authors： Pivarnik JM

更新日期：1996-08-01 00:00:00

abstract：:Increased hemolysis in the presence of severe neonatal hyperbilirubinemia appears to augment the risk of bilirubin neurotoxicity. The mechanism of this intensifying effect is uncertain. In direct antiglobulin titer (DAT) positive, isoimmune hemolytic disease, the bilirubin threshold at which neurotoxicity occurs appea...

journal_title：Seminars in perinatology

authors： Kaplan M,Bromiker R,Hammerman C

更新日期：2014-11-01 00:00:00

abstract：:The developing heart undergoes a remarkable metabolic transformation as it adjusts to the higher-oxygen, extrauterine environment. During gestation, glycolysis and lactate oxidation constitute the major sources of adenosine triphosphate (ATP) for the fetal heart. After birth, however, there is a rapid shift from carbo...

journal_title：Seminars in perinatology

authors： Ascuitto RJ,Ross-Ascuitto NT

更新日期：1996-12-01 00:00:00

abstract：:Neonatal herpes simplex virus (HSV) infection is one of the life-threatening infections of newborns. It affects approximately 1,500 to 2,200 infants per year in the United States. Changes in the presentation of neonatal HSV infection over the past two decades include an increase in the frequency of skin, eye, and mout...

journal_title：Seminars in perinatology

authors： Jacobs RF

更新日期：1998-02-01 00:00:00

abstract：:Clinically silent upper genital tract microbial infections have been strongly associated with spontaneous preterm delivery, especially prior to 32 weeks gestational age. This condition represents a potentially preventable or reversible cause of preterm birth using safe, readily available, and inexpensive antibiotics. ...

journal_title：Seminars in perinatology

authors： Andrews WW,Goldenberg RL,National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network.

更新日期：2003-06-01 00:00:00

abstract：:Gene therapy carries the potential to treat more than 10,000 human monogenic diseases and benefit an even greater number of complex polygenic conditions. The repurposing of CRISPR/Cas9, an ancient bacterial immune defense system, into a gene-editing technology has armed researchers with a revolutionary tool for gene t...

journal_title：Seminars in perinatology

authors： Memi F,Ntokou A,Papangeli I

更新日期：2018-12-01 00:00:00

abstract：:Extreme hyperbilirubinemia can cause bilirubin neurotoxicity. Infants with glucose-6-phosphate dehydrogenase (G6PD) deficiency can develop hemolysis and thus are at high risk. We evaluated a device that quantitatively measures G6PD activity kinetically using digital microfluidics (DMF). Intra- and inter-instrument and...

journal_title：Seminars in perinatology

authors： Wong RJ,Montiel C,Kunda M,Stevenson DK,Bhutani VK

更新日期：2021-02-01 00:00:00

abstract：:It is clear that external vibroacoustic stimulation with the EAL produces remarkable changes in FHR and fetal movement patterns that are related to changes in fetal behavior. The clinical significance of these studies has been addressed in small series on human fetuses by many authors. There is an obvious lack of unif...

journal_title：Seminars in perinatology

authors： Gagnon R

更新日期：1989-10-01 00:00:00

abstract：:The studies described above collectively suggest that, whenever there is a decrease in fluid balance in the fetus, both fetal urine flow and tracheal secretion into the amniotic space are decreased. Conversely, when fetal hydration is increased, both urine and tracheal flows into the amniotic fluid may be increased. T...

journal_title：Seminars in perinatology

authors： Brace RA

更新日期：1986-04-01 00:00:00

abstract：:Health care simulation is a powerful educational tool to help facilitate learning for clinicians and change their practice to improve patient outcomes and safety. To promote effective life-long learning through simulation, the educator needs to consider individuals, their experiences, and their environments. Effective...

journal_title：Seminars in perinatology

authors： Zigmont JJ,Kappus LJ,Sudikoff SN

更新日期：2011-04-01 00:00:00

abstract：:Neuroblastoma is the most common malignant neoplasm occurring in the neonate and arguably the most variable in its presentation. This review examines differences in the tumor's clinical course in the context of known biologic determinants of behavior. Tumors that would go undetected except for prenatal ultrasonography...

journal_title：Seminars in perinatology

authors： Lukens JN

更新日期：1999-08-01 00:00:00

abstract：:Medical and psychological indications for lactation suppression are discussed, and methods for lactation suppression are evaluated. Medical indications for lactation suppression include 1) maternal anatomical abnormalities, such as inadequate secretory tissue and inverted nipples; 2) maternal breast infections and tu...

journal_title：Seminars in perinatology

authors： Harrison RG

更新日期：1979-07-01 00:00:00

abstract：:Infection is a serious complication among very low birth weight (VLBW) preterm infants hospitalized in neonatal intensive care units. This article reviews studies from the National Institute of Child Health and Human Development (NICHD) Neonatal Research Network including infection data from observational studies and ...

journal_title：Seminars in perinatology

authors： Stoll BJ,Hansen N

更新日期：2003-08-01 00:00:00

abstract：:Nonsteroidal anti-inflammatory drugs are frequently used during pregnancy (premature labor, polyhydramnios) and the immediate postnatal period (closure of patent ductus arteriosus). This article evaluates the renal effect of 3 nonspecific COX inhibitors (aspirin, indomethacin, and ibuprofen) in newborn rabbits. Five g...

journal_title：Seminars in perinatology

authors： Guignard JP

更新日期：2002-12-01 00:00:00

abstract：:This article reviews the literature on infectious diseases as a cause of stillbirth. Identifying a specific infection as a cause of stillbirth is limited by many obstacles. Nevertheless, "good faith" efforts estimate that approximately 9% to 15% of stillbirths are caused by infections. Infection may be especially impo...

journal_title：Seminars in perinatology

authors： Gibbs RS

更新日期：2002-02-01 00:00:00

abstract：:Prenatal diagnosis of fetal aneuploidy is a continuously and rapidly evolving area of research. Currently in the United States, the standard of care for screening pregnancies for aneuploidy involves assessment of maternal age together with the use of multiple second trimester maternal serum markers. This screening app...

journal_title：Seminars in perinatology

authors： Stewart TL,Malone FD

更新日期：1999-10-01 00:00:00

abstract：:Preterm births account for a substantial portion of infant mortality, the major difference in mortality between African-American and white births in the United States, and the key reason that US infant mortality exceeds that of other developed nations. Although preterm birth rates are higher in the African-American co...

journal_title：Seminars in perinatology

authors： Hogue CJ,Hargraves MA

更新日期：1995-08-01 00:00:00

abstract：:Concern over the influence of pregnancy-related alterations in hydration has prompted questions regarding the accuracy of using standard methods of determining body composition. We sought to investigate whether differences exist between body composition determined at 30 weeks and 39 weeks of gestation and postpartum, ...

journal_title：Seminars in perinatology

authors： Jaque-Fortunato SV,Khodiguian N,Artal R,Wiswell RA

更新日期：1996-08-01 00:00:00

abstract：:Perinatal health outcomes in the United States continue to worsen, with the greatest burden of inequity falling on Black birthing communities. Despite transdisciplinary literature citing structural racism as a root cause of inequity, interventions continue to be mostly physician-centered models of perinatal and reprod...

journal_title：Seminars in perinatology

authors： Julian Z,Robles D,Whetstone S,Perritt JB,Jackson AV,Hardeman RR,Scott KA

更新日期：2020-08-01 00:00:00

abstract：OBJECTIVE:Breastmilk is recommended as the exclusive source of nutrition for infants younger than 6 months due to the numerous health benefits for both infants and mothers. Although many women are prescribed medications during pregnancy and postpartum, limited data are available to assist women in weighing the benefits...

journal_title：Seminars in perinatology

authors： Sprague J,Wisner KL,Bogen DL

更新日期：2020-04-01 00:00:00

abstract：:Although a minor constituent by weight, surfactant protein B (SP-B) plays a major role in surfactant function. It is the unique structure of SP-B that promotes permeabilization, cross-linking, mixing, and fusion of phospholipids, facilitating the proper structure and function of pulmonary surfactant as well as contrib...

journal_title：Seminars in perinatology

authors： Guttentag S

更新日期：2008-10-01 00:00:00