Abstract:
:Understanding maternal mental health and cortisol regulation across pregnancy and the relationship to the development of the offspring's stress regulation is critical to a range of health outcomes. The aim of this study was to investigate infant and maternal cortisol in women with depression. Data were obtained from 241 pregnant women within the Mercy Pregnancy and Emotional Wellbeing Study (MPEWS), a selected pregnancy cohort study. Depression was measured using the Structured Clinical Interview for DSM-IV (SCID-IV) and repeat Edinburgh Postnatal Depression Scale (EPDS). Repeated measures of antidepressant use, stressful events, anxiety symptoms and maternal hair cortisol concentrations (HCC) and infant cortisol at 12 months postpartum in saliva and hair. Socio-emotional outcomes were measured at 12 months by maternal report on the Brief Infant and Toddler Socio-emotional Assessment (BITSEA). This study found that maternal depression was not associated with maternal HCC. Anxiety, stress and antidepressant use were not associated with maternal HCC. Independently, higher maternal 3rd trimester maternal depressive and anxiety symptoms were associated with lower infant cortisol response at 12 months of age. A higher number of postpartum stressful events was associated with lower infant cortisol response. Lower infant stress reactivity was associated with higher externalizing symptoms at 12 months of age. Future studies are required to understand implications for later mental health.
journal_name
Psychoneuroendocrinologyjournal_title
Psychoneuroendocrinologyauthors
Galbally M,van Rossum EFC,Watson SJ,de Kloet ER,Lewis AJdoi
10.1016/j.psyneuen.2019.104374subject
Has Abstractpub_date
2019-11-01 00:00:00pages
104374eissn
0306-4530issn
1873-3360pii
S0306-4530(19)30467-6journal_volume
109pub_type
杂志文章abstract::Inconsistent findings have been found on the relation between oxytocin levels and psychopathy or callous-unemotional (CU) traits in humans, potentially because the role of trauma in oxytocin secretion and the distinction between primary and secondary psychopathy have been overlooked so far. Primary psychopathy has a s...
journal_title:Psychoneuroendocrinology
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journal_title:Psychoneuroendocrinology
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doi:10.1016/j.psyneuen.2006.07.004
更新日期:2006-10-01 00:00:00
abstract::The effects of immobilization-induced stress on plasma testosterone levels and lipogenesis in the sebaceous gland were examined in male Syrian hamsters. To induce immobilization stress, the animals were placed in the prone position and wrapped with flexible steel wire gauze at room temperature. Plasma testosterone lev...
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journal_title:Psychoneuroendocrinology
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doi:10.1016/j.psyneuen.2018.07.013
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journal_title:Psychoneuroendocrinology
pub_type: 杂志文章
doi:10.1016/j.psyneuen.2005.05.011
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journal_title:Psychoneuroendocrinology
pub_type: 杂志文章
doi:10.1016/j.psyneuen.2018.06.023
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doi:10.1016/j.psyneuen.2020.104628
更新日期:2020-05-01 00:00:00
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journal_title:Psychoneuroendocrinology
pub_type: 杂志文章
doi:10.1016/j.psyneuen.2019.03.029
更新日期:2019-08-01 00:00:00
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journal_title:Psychoneuroendocrinology
pub_type: 杂志文章,随机对照试验
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更新日期:2008-11-01 00:00:00
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pub_type: 杂志文章
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更新日期:2016-11-01 00:00:00
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journal_title:Psychoneuroendocrinology
pub_type: 杂志文章
doi:10.1016/j.psyneuen.2019.03.010
更新日期:2019-07-01 00:00:00
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journal_title:Psychoneuroendocrinology
pub_type: 杂志文章
doi:10.1016/j.psyneuen.2013.05.016
更新日期:2013-11-01 00:00:00
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journal_title:Psychoneuroendocrinology
pub_type: 杂志文章,随机对照试验
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更新日期:2010-10-01 00:00:00
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journal_title:Psychoneuroendocrinology
pub_type: 杂志文章
doi:10.1016/j.psyneuen.2019.03.030
更新日期:2019-08-01 00:00:00
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doi:10.1016/s0306-4530(02)00065-3
更新日期:2003-08-01 00:00:00
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journal_title:Psychoneuroendocrinology
pub_type: 杂志文章,评审
doi:10.1016/j.psyneuen.2020.104721
更新日期:2020-09-01 00:00:00
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journal_title:Psychoneuroendocrinology
pub_type: 杂志文章
doi:10.1016/j.psyneuen.2008.05.006
更新日期:2008-09-01 00:00:00
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journal_title:Psychoneuroendocrinology
pub_type: 杂志文章
doi:10.1016/j.psyneuen.2019.03.025
更新日期:2019-08-01 00:00:00
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journal_title:Psychoneuroendocrinology
pub_type: 杂志文章
doi:10.1016/0306-4530(84)90008-8
更新日期:1984-01-01 00:00:00
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journal_title:Psychoneuroendocrinology
pub_type: 杂志文章
doi:10.1016/j.psyneuen.2018.03.018
更新日期:2018-06-01 00:00:00
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doi:10.1016/0306-4530(95)00005-9
更新日期:1995-01-01 00:00:00
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journal_title:Psychoneuroendocrinology
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2017-09-01 00:00:00
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journal_title:Psychoneuroendocrinology
pub_type: 杂志文章
doi:10.1016/j.psyneuen.2008.08.025
更新日期:2009-02-01 00:00:00
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journal_title:Psychoneuroendocrinology
pub_type: 杂志文章
doi:10.1016/j.psyneuen.2016.09.008
更新日期:2016-12-01 00:00:00
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journal_title:Psychoneuroendocrinology
pub_type: 杂志文章,评审
doi:10.1016/0306-4530(93)90025-g
更新日期:1993-01-01 00:00:00
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journal_title:Psychoneuroendocrinology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.psyneuen.2011.10.005
更新日期:2012-07-01 00:00:00
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journal_title:Psychoneuroendocrinology
pub_type: 杂志文章
doi:10.1016/0306-4530(83)90005-7
更新日期:1983-01-01 00:00:00
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journal_title:Psychoneuroendocrinology
pub_type: 杂志文章,评审
doi:10.1016/j.psyneuen.2009.04.007
更新日期:2009-12-01 00:00:00
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journal_title:Psychoneuroendocrinology
pub_type: 杂志文章
doi:10.1016/0306-4530(83)90027-6
更新日期:1983-01-01 00:00:00
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journal_title:Psychoneuroendocrinology
pub_type: 临床试验,杂志文章
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更新日期:1989-01-01 00:00:00