Dialysis disequilibrium syndrome revisited: Feeling "Disequilibrated" due to inner ear dyshomeostasis?

abstract：:This paper will show that the fractional difference in the human gender ratio (GR) between the GR(at death) for those born in solar cycle peak years (maxima) and the GR(at death) in those born in solar cycle non-peak years (minima), e.g., 0.023, divided by Pi, yields a reasonable approximation of the quantum mechanica...

journal_title：Medical hypotheses

authors： Davis GE Jr,Lowell WE

更新日期：2009-09-01 00:00:00

abstract：:An unexpected and novel finding is described and discussed here concerning the synaptic physiology of hippocampal slices during the period of recovery after brain dissection. Contrary to the common notion that the amplitude of synaptic responses recovers in a single exponential rising fashion, we found that synaptic r...

journal_title：Medical hypotheses

authors： Gourov AV

更新日期：2011-12-01 00:00:00

abstract：:The polyol pathway consists of two enzymes aldose reductase (AR) and sorbitol dehydrogenase (SDH); the former is the first enzyme in the polyol pathway, that catalyzes the reduction of glucose to sorbitol, the latter is the second one, that converts sorbitol to fructose using by NAD(+) as a cofactor. We along with oth...

journal_title：Medical hypotheses

authors： Amano S,Yamagishi S,Koda Y,Tsuneoka M,Soejima M,Okamoto T,Inagaki Y,Yamada K,Kimura H

更新日期：2003-04-01 00:00:00

abstract：:In this work a new theory of acoustic signal detection in the inner ear and an experimental explanation of the causes of bifilar cochlear structure was presented. Our innovative approach describes sound detection in a completely different way from the one currently adopted. It requires analyzing the inner ear system i...

journal_title：Medical hypotheses

authors： Dora J,Wojcieszak D,Kaczmarek D,Mazur M,Aksenczuk A

更新日期：2020-02-18 00:00:00

abstract：:Salt is a major mineral element that plays fundamental roles in health and disease. Excessive salt intake is a major cause of hypertension, cardiovascular disease and stroke. Miscarriage and preeclampsia are the most common pregnancy complications with multiple etiological factors, including inflammatory and autoimmun...

journal_title：Medical hypotheses

authors： Abdoli A

更新日期：2016-04-01 00:00:00

abstract：:Although the classical ideal is that scientific theories are evaluated by a careful teasing-out of their internal logic and external implications, and checking whether these deductions and predictions are in-line-with old and new observations; the fact that so many vague, dumb or incoherent scientific theories are app...

journal_title：Medical hypotheses

authors： Charlton BG

更新日期：2008-09-01 00:00:00

abstract：:Trigeminal neuralgia (TN) is a rare form of neuropathic pain that results in sudden, unilateral and recurrent pains in the distribution of one or more branches of the trigeminal nerve. The aetiology of TN remains unclear and several theories have been proposed. Many medical and surgical methods have been applied with ...

journal_title：Medical hypotheses

authors： Collet C,Haen P,Laversanne S,Brignol L,Thiéry G

更新日期：2013-12-01 00:00:00

abstract：:N-acetylaspartate (NAA) is an intermediary metabolite that is found in relatively high concentrations in the human brain. More specifically, NAA is so concentrated in the neurons that it generates one of the most visible peaks in nuclear magnetic resonance (NMR) spectra, thus allowing NAA to serve as "a neuronal marke...

journal_title：Medical hypotheses

authors： Clark JF,Doepke A,Filosa JA,Wardle RL,Lu A,Meeker TJ,Pyne-Geithman GJ

更新日期：2006-01-01 00:00:00

abstract：:The cumulative incidence of uterine leiomyoma at age 50 is ≈ 70% in White women and >80% in Black women. Although risk factor research is limited, increasing age, and being premenopausal, nulliparous or Black are risk factors for leiomyomas. Black women tend to have larger leiomyomas and be younger at diagnosis. Surpr...

journal_title：Medical hypotheses

authors： Wegienka G

更新日期：2012-08-01 00:00:00

abstract：:Late follicular progesterone (P) elevation continues to complicate a significant part of assisted reproductive technologies (ART) cycles, despite the ardent employment of gonadotropin releasing hormone (GnRH) analogues. In women with good ovarian reserve, late follicular P elevation is believed to be the result of the...

journal_title：Medical hypotheses

authors： Younis JS

更新日期：2019-04-01 00:00:00

abstract：:Irritable Bowel Syndrome (IBS) is a condition that may be marked by abdominal pain, bloating, fullness, indigestion, belching, constipation and/or diarrhea. IBS symptoms can result from malabsorption of fructose. Fructose is a monosaccharide found naturally in small quantities in fruits and some vegetables, and in muc...

journal_title：Medical hypotheses

authors： DiNicolantonio JJ,Lucan SC

更新日期：2015-09-01 00:00:00

abstract：:Microbial resistance to conventional as well as newly introduced drugs is a hallmark feature of several infectious diseases, notably tuberculosis. It is hypothesized that the greater the selective pressure exerted by increasingly potent drugs, the more rapidly is an organism able to adapt to a drug-containing environm...

journal_title：Medical hypotheses

authors： Basu A,Mistry NF,Antia NH

更新日期：1995-11-01 00:00:00

abstract：:The adaptive value of sleep remains unknown in spite of the intense research performed throughout the last decades. However, few sleep researchers are aware of the difficulties posed by the blind acceptance of an extreme adaptationist viewpoint. Under this philosophy, every anatomical and functional detail present in ...

journal_title：Medical hypotheses

authors： Gamundí A,Akaârir M,Coenen AM,Esteban S,Rial RV,Nicolau MC

更新日期：2005-01-01 00:00:00

abstract：:Postoperative cognitive dysfunction (POCD) is reported to occur frequently after all types especially cardiac surgery in elderly patients. It can be short-term or long-term and some cases even develop into Alzheimer's disease (AD). Although multi-risk factors associated with POCD have been identified, the etiology and...

journal_title：Medical hypotheses

authors： Fan L,Wang TL,Xu YC,Ma YH,Ye WG

更新日期：2011-05-01 00:00:00

abstract：:In both African AIDS populations and homosexual populations outside of Africa, a high incidence of syphilis and multiple exposures to infectious diseases results in frequent, often abusive use of antibiotics. Epidemiological evidence exists for chemical immunosuppression resulting from antibiotics and other prescribed...

journal_title：Medical hypotheses

authors： McKenna JJ,Miles R,Lemen D,Dunford SA,Renirie R

更新日期：1986-12-01 00:00:00

abstract：:An increase in pro-inflammatory cytokines, decrease in endothelial nitric oxide (eNO) and adiponectin levels and an alteration in hypothalamic peptides and gastrointestinal hormones such as incretins and cholecystokinin that regulate satiety, hunger, and food intake occur in metabolic syndrome. Thus, metabolic syndrom...

journal_title：Medical hypotheses

authors： Das UN

更新日期：2011-03-01 00:00:00

abstract：:Doppler sonography is used as a routine test for detection of renal artery stenosis (RAS). Although increased peak systolic velocity at the site of the narrowing is a widely accepted method for assessing main renal artery stenosis, tardus parvus phenomenon detected on the downstream blood flow has been used as an alte...

journal_title：Medical hypotheses

authors： Cavalcante Araújo N

更新日期：2019-03-01 00:00:00

abstract：:Hepatic encephalopathy (HE) is a common neuropsychiatric complication of liver disease affecting about 20-30% patients with cirrhosis. HE may only affect quality of life (e.g. impairments in attention; coordination; driving ability), but in some patients this progresses to coma and death; defining mortality in those w...

journal_title：Medical hypotheses

authors： Jalan R,Wright G,Davies NA,Hodges SJ

更新日期：2007-01-01 00:00:00

abstract：:Although fibrosis and emphysema are in many ways on opposite ends of the pulmonary parenchymal disease spectrum, they seem to share common pathomechanistic steps. This is illustrated by the coexistence of both entities in lungs of individuals with combined pulmonary fibrosis and emphysema. Macroproteins elastin and co...

journal_title：Medical hypotheses

authors： Janssen R,de Brouwer B,von der Thüsen JH,Wouters EFM

更新日期：2018-11-01 00:00:00

abstract：:In idiopathic scoliosis the convexity of the thoracic curve of the vertebral column is most commonly directed toward the right side. The right lung is normally larger than the left lung. This asymmetry acting through chest wall movement is hypothesized to exert rotatory forces on the vertebral column. The result, in p...

journal_title：Medical hypotheses

authors： Del Bigio MR

更新日期：1989-04-01 00:00:00

abstract：:A wide range of hyperimmune-associated diseases plague post-industrial society, with a prevalence and impact that is staggering. Strong evidence points towards a loss of helminths from the ecosystem of the human body (the human biome) as the most important factor in this epidemic. Helminths, intestinal worms which are...

journal_title：Medical hypotheses

authors： Bilbo SD,Wray GA,Perkins SE,Parker W

更新日期：2011-10-01 00:00:00

abstract：:Atherosclerosis is a common disease whose complications, such as myocardial infarction, are a leading cause of mortality worldwide. Therefore, ideas which try to explain the circumstances of atherosclerotic plaque initiation and progression are warranted. We hypothesize that low-grade inflammation in early life (espec...

journal_title：Medical hypotheses

authors： Kowara M,Kasarełło K,Czarzasta K,Opolski G,Cudnoch-Jędrzejewska A

更新日期：2019-01-01 00:00:00

abstract：:In normal and hypertensive subjects, many stimuli which increase ACTH secretion also increase blood pressure and conversely, many drugs which decrease ACTH secretion also decrease blood pressure. We postulate that the hypothalamopituitary adrenal axis plays a role in blood pressure regulation in normal and hypertensiv...

journal_title：Medical hypotheses

authors： Whitworth JA,McLachlan-Troup N,Scoggins BA

更新日期：1987-07-01 00:00:00

abstract：:Recent work by molecular biologists into the behaviour of progesterone receptors (PR) has suggested an aetiological hypothesis for premenstrual syndrome (PMS). The proposition is that PMS is related to the transport by PR of sufficient progesterone (P) molecules into the cell nuclei during menstruating years. PR are w...

journal_title：Medical hypotheses

authors： Dalton K

更新日期：1990-04-01 00:00:00

abstract：:Over-proliferation of SMC (smooth muscle cell) is one characteristics of atherosclerosis. One well accepted mechanism is that the decrease of ECs (endothelial cells) induced by over apoptosis leads to endothelial dysfunction, which in turn results in over-proliferation of SMC. Obviously, the mechanism works after endo...

journal_title：Medical hypotheses

authors： Qin C,Liu Z

更新日期：2007-01-01 00:00:00

abstract：:Meditation is a complex mental process involving changes in cognition, sensory perception, affect, hormones, and autonomic activity. Meditation has also become widely used in psychological and medical practices for stress management as well as a variety of physical and mental disorders. However, until now, there has b...

journal_title：Medical hypotheses

authors： Newberg AB,Iversen J

更新日期：2003-08-01 00:00:00

abstract：:Cardiovascular diseases like myocardial infarction, complex congenital heart disease, and subsequent heart failure are a leading cause of morbidity and mortality. Recent advances in tissue engineering arise to address the lack of available tissues and organs for transplantation because cells alone are not capable of r...

journal_title：Medical hypotheses

authors： Wu KH,Cui B,Yu CT,Liu YL

更新日期：2006-01-01 00:00:00

abstract：UNLABELLED:CRPS is an acute pain disease expressed as chronic pain with a severe loss of tissue and function. CRPS usually occurs after minor injuries and then progresses in a way that is scarcely controllable, or completely uncontrollable. This article addresses the functional control mechanism of a biological organis...

journal_title：Medical hypotheses

authors： van der Veen P

更新日期：2015-11-01 00:00:00

abstract：:The role of ozone on earth is controversial, as in the stratosphere it is protective against excessive ultra violet irradiation, and in the troposphere it is toxic for animals and plants. The effectiveness of ozone against pathogens is well recognized and ozone appears to be the best agent for sterilization of water. ...

journal_title：Medical hypotheses

authors： Bocci V

更新日期：1996-02-01 00:00:00

abstract：:Amyloid beta-protein is a major focus in efforts to understand the etiology of Alzheimer disease yet there is little known about the mechanism of its deposition in plaques. I propose deposition of amyloid in neuritic plaques depends on the remains of neurofibrillary tangles after neuronal death. The interaction of the...

journal_title：Medical hypotheses

authors： Perry G

更新日期：1993-04-01 00:00:00