Investigation of antioxidative effects of a cardioprotective solution in heart tissue.

abstract：:Studies have shown that long noncoding RNA Zinc finger E-box-binding homeobox 2 antisense RNA 1 (ZEB2-AS1) is involved in the progression of lung cancer, bladder cancer, and hepatocellular carcinoma. However, its role in the pathogenesis of gastric cancer remains unknown. The Wnt/β-catenin pathway contributes to the d...

journal_title：Molecular and cellular biochemistry

authors： Wang F,Zhu W,Yang R,Xie W,Wang D

更新日期：2019-06-01 00:00:00

abstract：:The regulation patterns of gastric acid secretion in rats were investigated. Pentagastrin and histamine stimulate gastric acid secretion, but the inhibitors of DNA-dependent synthesis of RNA and of proteins prevent only the pentagastrin action. It has been found that pentagastrin induces histidine decarboxylase in gas...

journal_title：Molecular and cellular biochemistry

authors： Salganik RI,Bersimbaev RI,Argutinskaya SV,Kiseleva EV,Khristolyubova NB,Deribas VI

更新日期：1976-09-30 00:00:00

abstract：:Cultured human and rat endothelial cells were used to study cellular toxicity and Ca2+ signalling upon exposure to reactive oxygen species. Superoxide and hydrogen peroxide (O2.-/H2O2) were produced by the hypoxanthine/xanthine oxidase system (HX/XO) and caused intracellular Ca2+ concentration ([Ca2+]i) to rise steadi...

journal_title：Molecular and cellular biochemistry

authors： Volk T,Hensel M,Kox WJ

更新日期：1997-06-01 00:00:00

abstract：:We propose a simple mechanism which enables decrease of the free pool of channelled metabolite in static spatial channelling, when the concentration of the enzyme consuming the channelled metabolite is greater than the concentration of the enzyme producing this metabolite. Spatial channelling occurs between two enzyme...

journal_title：Molecular and cellular biochemistry

authors： Korzeniewski B,Quant PA

更新日期：1997-04-01 00:00:00

abstract：:The activity of yeasts citrate synthase in cells grown under different hypoxic conditions has been investigated. A linear relationship between the citrate synthase activity and the respiratory capacity of the cells has been found. When Saccharomyces cerevisiae was grown on fermentable substrates the activity decreased...

journal_title：Molecular and cellular biochemistry

authors： Nuñez de castro I,Arias de Saavedra JM,Machado A,Mayor F

更新日期：1976-09-30 00:00:00

abstract：:1. Glucokinase is one of four glucose phosphorylating enzymes present in rat liver. Its distinctive features are a high K-m for glucose (high-K-m isozyme) and a rather narrow substrate specificity. In contrast, the other three enzymes, collectively called hexokinases or low-K-m isozymes, exhibit low K-m values for glu...

journal_title：Molecular and cellular biochemistry

authors： Niemeyer H,Ureta T,Clark-Turri L

更新日期：1975-02-28 00:00:00

abstract：:Carbohydrate has been removed from a number of glycoproteins without major effect on the structure or enzyme activity of the protein. Thus carbohydrate has been suggested to underly a non-primary function for proteins, such as in relatively non-specific interactions with other carbohydrates or macromolecules, stabiliz...

journal_title：Molecular and cellular biochemistry

authors： West CM

更新日期：1986-11-01 00:00:00

abstract：:Activating mutations within the tyrosine kinase (TK) domain of epidermal growth factor receptor (EGFR) gene are observed in 10 ~ 30% of the patients diagnosed with non-small cell lung cancer (NSCLC), and are causally related to NSCLC initiation and progression. Treatments with tyrosine kinase inhibitors (TKIs) targeti...

journal_title：Molecular and cellular biochemistry

authors： Chen C,Peng S,Li P,Ma L,Gan X

更新日期：2020-12-01 00:00:00

abstract：:Two membrane bound guanylate cyclases are expressed in vertebrate photoreceptor cells. They serve a key function in photoreceptor physiology as they synthesize the intracellular transmitter of photoexcitation guanosine 3',5'-cyclic monophosphate (cGMP). Both cyclases named ROS-GC1 and ROS-GC2 form a subclass of membra...

journal_title：Molecular and cellular biochemistry

authors： Koch KW,Duda T,Sharma RK

更新日期：2002-01-01 00:00:00

abstract：:Glycyrrhizin, a major constituent of licorice (Glycyrrhiza glabra) root, has been reported to ameliorate insulin resistance, hyperglycemia, dyslipidemia, and obesity in rats with metabolic syndrome. Liver dysfunction is associated with this syndrome. The objective of this study is to investigate the effect of glycyrrh...

journal_title：Molecular and cellular biochemistry

authors： Sil R,Ray D,Chakraborti AS

更新日期：2015-11-01 00:00:00

abstract：:Diabetic peripheral neuropathy (DPN) is one of the most important complications in diabetes mellitus (DM), which has been reported to be modulated by long non-coding RNAs (lncRNAs). The purpose of the current study is to explore the regulatory mechanism of lncRNA HCG18 on DPN in vitro. The expression of lncRNA HCG18, ...

journal_title：Molecular and cellular biochemistry

authors： Ren W,Xi G,Li X,Zhao L,Yang K,Fan X,Gao L,Xu H,Guo J

更新日期：2020-09-29 00:00:00

abstract：:Recent reports considered that it was the disturbance of calcium homeostasis and the accumulation of misfolded proteins in the endoplasmic reticulum (ER) that activated hepatic stellate cells (HSCs) apoptosis and promoted fibrosis resolution. However, the signal-transducing events that are activated by ER stress after...

journal_title：Molecular and cellular biochemistry

authors： Huang Y,Li X,Wang Y,Wang H,Huang C,Li J

更新日期：2014-09-01 00:00:00

abstract：:The application of nucleic acid hybridization techniques to the study of liver regeneration has led to a revision of some well-established ideas about the patterns of gene expression during regenerative growth. This paper focuses on two broad problems: a) the extent to which mRNA populations in regenerating liver diff...

journal_title：Molecular and cellular biochemistry

authors： Fausto N

更新日期：1984-01-01 00:00:00

abstract：:The mechanism of the effect of beta-hydroxy-beta-methylbutyrate (HMB) on protein degradation induced by lipopolysaccharide (LPS) has been evaluated in murine myotubes. HMB (50 muM) completely attenuated total protein degradation induced by LPS (1-100 ng/ml), formation of reactive oxygen species (ROS) and activation of...

journal_title：Molecular and cellular biochemistry

authors： Russell ST,Tisdale MJ

更新日期：2009-10-01 00:00:00

abstract：:We have demonstrated that in normal and b/b rat red blood cells (RBCs) hsp70-like protein (heat shock protein 70-like) is localized in the cytosol and it is exported via exosomes during in vivo reticulocytes maturation. As we have presumed, in the mutant (b/b) rat, hsp70-like protein transfers from cytosol to the RBC ...

journal_title：Molecular and cellular biochemistry

authors： Zarić J,Glisin V,Popović Z

更新日期：1998-01-01 00:00:00

abstract：:Human cardiomyopathy has been extensively studied in the last decade, and knowledge of the functional and structural alterations of the heart has grown. However, understanding of the pathogenesis has come mostly from experimental studies. A number of work have been designed to elucidate if alterations of the contracti...

journal_title：Molecular and cellular biochemistry

authors： Veksler V,Ventura-Clapier R

更新日期：1994-04-01 00:00:00

abstract：:Thymol is a phytochemical component present in many plants used as food additive in order to promote animal growth due to its several biological properties. However, possible side effects of thymol remain poorly known limited to few reports. In this sense, we evaluated the enzymes of the purinergic signaling such as, ...

journal_title：Molecular and cellular biochemistry

authors： Baldissera MD,Souza CF,De Matos AFIM,Baldisserotto B,Stefani LM,da Silva AS

更新日期：2019-02-01 00:00:00

abstract：:Subsequent to the first alpha 2-adrenergic receptor (alpha 2-AR) gene cloning of alpha 2-C10 from human platelet, cloning of the first rodent alpha 2-AR cDNA, cA2-47, was reported. Based on the structural and limited pharmacological comparison, it was concluded that the rodent receptor is a molecular and pharmacologic...

journal_title：Molecular and cellular biochemistry

authors： Wypijewski K,Duda T,Sharma RK

更新日期：1995-03-23 00:00:00

abstract：:Treatment of bovine pulmonary artery smooth muscle plasma membrane suspension with the oxidant tert-butylhydroperoxide (t-buOOH) increases Ca2+ATPase activity. The smooth muscle plasma membrane possesses a Ca2+ dependent protease activity in the gelatin containing zymogram having an apparent molecular mass of 72 kDa. ...

journal_title：Molecular and cellular biochemistry

authors： Das S,Chakraborti T,Mandal M,Mandal A,Chakraborti S

更新日期：2002-08-01 00:00:00

abstract：:The aim of our study is to explore the regulation of C1QTNF1-AS1 on its target miR-221-3p/SOCS3 in human hepatocellular carcinoma (HCC). To explore the underlying molecular regulation of non-coding RNA for HCC, differentially expressed patterns of lncRNAs and genes were examined by RNA-seq. GO and KEGG pathway analysi...

journal_title：Molecular and cellular biochemistry

authors： Han W,Yu G,Meng X,Hong H,Zheng L,Wu X,Zhang D,Yan B,Ma Y,Li X,Wang Q

更新日期：2019-10-01 00:00:00

abstract：:Proteoglycans carrying chondroitin sulfate side chains have been shown to fulfill important biological functions in development, disease, and signaling. One area of considerable interest is the functional importance of chondroitin sulfates as inhibitors of the regeneration of axonal projections in the mammalian centra...

journal_title：Molecular and cellular biochemistry

authors： Klüppel M

更新日期：2011-05-01 00:00:00

abstract：:In the context of high human consumption of fructose diets, there is an imperative need to understand how dietary fructose intake influence cellular and molecular mechanisms and thereby affect β-cell dysfunction and insulin resistance. While evidence exists for a relationship between high-fat-induced insulin resistanc...

journal_title：Molecular and cellular biochemistry

authors： Balakumar M,Raji L,Prabhu D,Sathishkumar C,Prabu P,Mohan V,Balasubramanyam M

更新日期：2016-12-01 00:00:00

abstract：:Lysosomes are a cell organelle type processing antimicrobial activity. Here, we investigate the lysosomal activity in a primary cell line, bovine aortic endothelial cells (BAECs), during cellular aging, based on the antimicrobial activity of lysosomes isolated from BAECs at cell passages 4, 6, 8, and 10. Cytochemical ...

journal_title：Molecular and cellular biochemistry

authors： Yoon J,Kim KJ,Choi YW,Shin HS,Kim YH,Min J

更新日期：2010-07-01 00:00:00

abstract：:Pre-purified preparations of myoinositol-1-phosphate synthase (E.C. 5.5.1.4) from rat testes can be purified to homogeneity by first crystallizing the enzyme according to JAKOBY and then recrystallizing it at a pH value close to the isoelectric point while slowly increasing the temperature from 0 to 15 degrees C. This...

journal_title：Molecular and cellular biochemistry

authors： Pittner F,Hoffmann-Ostenhof O

更新日期：1979-12-14 00:00:00

abstract：:The aim of the current study was to comparatively investigate the effect of inhibition of nitric oxide (NO) production by N-nitro-L-arginine methyl ester (L-NAME), an isoform non-specific inhibitor of nitric oxide synthase (NOS), after oral mucosal incision on wound tissue NO levels. A standard incision was applied to...

journal_title：Molecular and cellular biochemistry

authors： Coşkun S,Karataş F,Acartürk F,Olmuş H,Selvi M,Erbaş D

更新日期：2005-10-01 00:00:00

abstract：:Lipoamidase is found to be able to release various membrane-anchored enzymes from the membrane compartment of pig brain. Released enzymes revealed their intact enzyme activities in the soluble fraction. Lipoamidase could release at least two types of anchored enzymes, i.e. glycosyl-phosphatidylinositol-bonded and myri...

journal_title：Molecular and cellular biochemistry

authors： Oizumi J,Hayakawa K

更新日期：1992-09-22 00:00:00

abstract：:Changes in demands for Na+ transport alter expression of the Na+,K+ -ATPase subunit isoforms. In skeletal muscle, the effects of these changes on expression the alpha2 isoform, the major isoform expressed in differentiated muscle cell, is not known. Therefore, this study examines regulation of the alpha-subunit isofor...

journal_title：Molecular and cellular biochemistry

authors： Ladka R,Ng YC

更新日期：2000-08-01 00:00:00

abstract：:The recombinant eukaryotic expression vector pCMV4-rmCGbeta, inserted full-length cDNA of the beta-subunit of rhesus monkey chorionic gonadotropin (rmCGbeta), as DNA immuno-contraceptive against CGbeta glycoprotein, has previously demonstrated the biological expression of rmCGbeta in vitro and in vivo. The plasmid DNA...

journal_title：Molecular and cellular biochemistry

authors： Chen Y,Liu Z,Yang Y,Chen YZ,Peng JP

更新日期：2002-02-01 00:00:00

abstract：:Both reactive oxygen- and nitrogen-derived reactive species play important roles in physiological and pathophysiological conditions. Flavones, luteolin and luteolin-7-O-glucoside along with a rich plant source of both flavones, namely dandelion (Taraxacum officinale) flower extract were studied for antioxidant activit...

journal_title：Molecular and cellular biochemistry

authors： Hu C,Kitts DD

更新日期：2004-10-01 00:00:00

abstract：:There is general agreement that the connexin43 gap junction protein is a substrate for phosphorylation by protein kinase C but there is no similar consensus regarding the action of protein kinase A. Our previous studies demonstrated that channels formed by connexin43 were reversibly gated in response to microinjected ...

journal_title：Molecular and cellular biochemistry

authors： Shah MM,Martinez AM,Fletcher WH

更新日期：2002-09-01 00:00:00