Abstract:
:We have demonstrated that in normal and b/b rat red blood cells (RBCs) hsp70-like protein (heat shock protein 70-like) is localized in the cytosol and it is exported via exosomes during in vivo reticulocytes maturation. As we have presumed, in the mutant (b/b) rat, hsp70-like protein transfers from cytosol to the RBC membrane. In the normal rat RBCs this happens when those cells are submitted to heat stress conditions. Our study indicates that the presence of hsp70-like protein in the b/b rat RBC plasma membrane is consistent with a primary defect and is not a consequence of life long stress, i.e. hypoxia.
journal_name
Mol Cell Biochemjournal_title
Molecular and cellular biochemistryauthors
Zarić J,Glisin V,Popović Zdoi
10.1023/a:1006877026611subject
Has Abstractpub_date
1998-01-01 00:00:00pages
119-25issue
1-2eissn
0300-8177issn
1573-4919journal_volume
178pub_type
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journal_title:Molecular and cellular biochemistry
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journal_title:Molecular and cellular biochemistry
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