Messenger RNA in regenerating liver: implications for the understanding of regulated growth.

abstract：:Gram negative sepsis and septic shock continue to be a major medical problem, with a complex physiopathology and it is associated with high mortality. Although secretion of cytokines such as tumor necrosis factor-alpha by macrophages is the principal host mediator of septic shock, other characteristic functions of mac...

journal_title：Molecular and cellular biochemistry

authors： Víctor VM,Miñano M,Guayerbas N,Del Río M,Medina S,De la Fuente M

更新日期：1998-12-01 00:00:00

abstract：:Casein kinase II is a protein serine/threonine kinase that is ubiquitously distributed in eukaryotes. Molecular cloning studies and protein sequence analysis of purified proteins have demonstrated the existence of two related, but distinct, isoenzymic forms of its catalytic subunit in mammals and birds. At present, th...

journal_title：Molecular and cellular biochemistry

authors： Litchfield DW,Lüscher B

更新日期：1993-11-01 00:00:00

abstract：:Signal transduction pathways control various biological processes in cells leading to distinct cellular functions. Protein-protein interactions and post-translational modifications are the physiological events that occur in signaling pathway. p38 MAPK are known to be involved in regulating wide range of cellular proce...

journal_title：Molecular and cellular biochemistry

authors： Rini J,Anbalagan M

更新日期：2017-11-01 00:00:00

abstract：:Salidroside, a phenol glycoside of plant origin, has been documented to possess a broad spectrum of pharmacological properties, including protective effects against neuronal death induced by different insults. To provide further insights into the neuroprotective functions peculiar to salidroside, this study used prima...

journal_title：Molecular and cellular biochemistry

authors： Zhang S,Chen X,Yang Y,Zhou X,Liu J,Ding F

更新日期：2011-08-01 00:00:00

abstract：:Previous studies reported that estrogen receptor β (ERβ) is localized to mitochondria, whereas little is known about the physiological functions of mitochondrial ERβ. In the present study, we explored the role of mitochondrial ERβ in regulating apoptosis using stable ERβ-expressing and ERβ knockdown cells lines. We fo...

journal_title：Molecular and cellular biochemistry

authors： Liang J,Xie Q,Li P,Zhong X,Chen Y

更新日期：2015-03-01 00:00:00

abstract：:Iron ions play a central role in .OH radicals formation and induction of oxidative stress in living organisms. Iron-catalyzed .OH radical formation degrades deoxyribose to thiobarbituric acid reactive substances (TBA-RS). This paper analyzes kinetic properties of the Fe(III)-EDTA-catalyzed deoxyribose degradation in t...

journal_title：Molecular and cellular biochemistry

authors： Hermes-Lima M,Wang EM,Schulman HM,Storey KB,Ponka P

更新日期：1994-08-17 00:00:00

abstract：:A number of nutritional supplements containing antioxidants are advertised for better vision health. Do they benefit the average consumer? The literature was examined for the effectiveness of antioxidants for human eye health, and for the intricacies in collection of such evidence. The following diseases were consider...

journal_title：Molecular and cellular biochemistry

authors： Grover AK,Samson SE

更新日期：2014-03-01 00:00:00

abstract：:Cytochrome P450c17, encoded by the CYP17 gene, is a component of 17alpha-hydroxylase/17,20 lyase which catalyses 17alpha-hydroxylation of pregnenolone or progesterone, required for glucocorticosteroid and androgen synthesis. It has been reported that transforming growth factor beta (TGF-beta) decreases both basal and ...

journal_title：Molecular and cellular biochemistry

authors： Derebecka-Holysz N,Lehmann TP,Holysz M,Trzeciak WH

更新日期：2008-01-01 00:00:00

abstract：:In mammals, protein kinase CK2 has two isozymic forms of its catalytic subunit, designated CK2alpha and CK2alpha'. CK2alpha and CK2alpha' exhibit extensive similarity within their catalytic domains but have completely unrelated C-terminal sequences. To systematically examine the cellular functions of each CK2 isoform ...

journal_title：Molecular and cellular biochemistry

authors： Litchfield DW,Bosc DG,Canton DA,Saulnier RB,Vilk G,Zhang C

更新日期：2001-11-01 00:00:00

abstract：:Thymoquinone (TQ) is a highly perspective chemotherapeutic agent against gliomas and glioblastomas because of its ability to cross the blood-brain barrier and its selective cytotoxicity for glioblastoma cells compared to primary astrocytes. Here, we tested the hypothesis that TQ-induced mild oxidative stress provokes ...

journal_title：Molecular and cellular biochemistry

authors： Krylova NG,Drobysh MS,Semenkova GN,Kulahava TA,Pinchuk SV,Shadyro OI

更新日期：2019-12-01 00:00:00

abstract：:Gentamicin (GM) is an antibiotic whose clinical use is limited by its nephrotoxicity. Experimental evidences suggest a role of reactive oxygen species in GM-induced nephrotoxicity. In this work we explored the effect of diallyl sulfide (DAS), a garlic-derived compound with antioxidant properties, on GM-induced nephrot...

journal_title：Molecular and cellular biochemistry

authors： Pedraza-Chaverrí J,Maldonado PD,Barrera D,Cerón A,Medina-Campos ON,Hernández-Pando R

更新日期：2003-12-01 00:00:00

abstract：:To investigate whether the action potential duration (APD) or resting tension was dependent on global ATP content, and whether they were preferentially dependent on glycolytic ATP, APD and resting tension were measured under various metabolic inhibition with corresponding measurement of ATP content in guinea pig ventr...

journal_title：Molecular and cellular biochemistry

authors： Hayashi H,Terada H,McDonald TF

更新日期：1999-04-01 00:00:00

abstract：:Understanding the driving forces for the hepatic uptake of endogenous and exogenous substrates in isolated cells and organs is fundamental to describing the underlying hepatic physiology/pharmacology. In this study we investigated whether uptake of plasma protein-bound [3H]-palmitate across the hepatocyte wall is gove...

journal_title：Molecular and cellular biochemistry

authors： Burczynski FJ,Hung D,Wang GQ,Elmadhoun B,Lewis A,Chang P,Rajaraman G,Robert S

更新日期：2005-02-01 00:00:00

abstract：:Calpain inhibitors show the potential to serve as non-surgical alternatives in treating diabetic cataract and other types of these disorders. Here, we have tested the recently developed calpain inhibitor, SJA6017, for its ability to inhibit cataractogenesis in porcine lenses. These lenses were incubated in increasing ...

journal_title：Molecular and cellular biochemistry

authors： Biswas S,Harris F,Singh J,Phoenix DA

更新日期：2004-06-01 00:00:00

abstract：:Cysteine-rich secretory protein 3 (CRISP-3) is upregulated in prostate cancer as compared to the normal prostate tissue. Higher expression of CRISP-3 has been linked to poor prognosis and hence it has been thought to act as a prognostic marker for prostate cancer. It is proposed to have a role in innate immunity but i...

journal_title：Molecular and cellular biochemistry

authors： Pathak BR,Breed AA,Apte S,Acharya K,Mahale SD

更新日期：2016-01-01 00:00:00

abstract：:Fasting is accompanied by a decrease in collagen biosynthesis. The mechanism of this phenomenon involves inhibition of prolidase activity, an enzyme that plays a key role in upregulation of collagen metabolism. The mechanism of fasting-induced inhibition of prolidase activity is not known. Phosphoenolpyruvate (PEP) is...

journal_title：Molecular and cellular biochemistry

authors： Cechowska-Pasko M,Palka J,Bańkowski E

更新日期：2004-10-01 00:00:00

abstract：:Sensitive to Apoptosis Gene (SAG), a RING component of SCF E3 ubiquitin ligase, was shown to be phosphorylated by protein kinase CK2 at the Thr10 residue. It is, however, unknown whether this phosphorylation is stress-responsive or whether the phosphorylation changes its E3 ubiquitin ligase activity. To address these,...

journal_title：Molecular and cellular biochemistry

authors： He H,Tan M,Pamarthy D,Wang G,Ahmed K,Sun Y

更新日期：2007-01-01 00:00:00

abstract：:Streptococcus pneumoniae is an important pathogen of pneumonia in human. Human alveolar epithelium acts as an effective barrier and is an active participant in host defense against invasion of bacterial by production of various mediators. Sirtuin 1 (SIRT1), the prototypic class III histone deacetylase, is involved in ...

journal_title：Molecular and cellular biochemistry

authors： Lin L,Wen SH,Guo SZ,Su XY,Wu HJ,Chong L,Zhang HL,Zhang WX,Li CC

更新日期：2014-09-01 00:00:00

abstract：:Thymol is a phytochemical component present in many plants used as food additive in order to promote animal growth due to its several biological properties. However, possible side effects of thymol remain poorly known limited to few reports. In this sense, we evaluated the enzymes of the purinergic signaling such as, ...

journal_title：Molecular and cellular biochemistry

authors： Baldissera MD,Souza CF,De Matos AFIM,Baldisserotto B,Stefani LM,da Silva AS

更新日期：2019-02-01 00:00:00

abstract：:This comparative study investigates the relationship between sarcoplasmic reticulum (SR) calcium(Ca2+)-ATPase transport activity and phospholamban (PLB) phosphorylation in whole cardiac homogenates of spontaneously hypertensive rats (SHR) and their parent, normotensive Wistar Kyoto (WKY) strain during early postnatal ...

journal_title：Molecular and cellular biochemistry

authors： Freestone N,Singh J,Krause EG,Vetter R

更新日期：1996-10-01 00:00:00

abstract：:It has been reported that apelin functions as an adipokine, which has been associated to obesity and insulin resistance. The objective of this study was to analyze the apelin mRNA expression in white adipose tissue (WAT) from high-fat (Cafeteria) fed rats, in order to examine potential relationships with obesity marke...

journal_title：Molecular and cellular biochemistry

authors： García-Díaz D,Campión J,Milagro FI,Martínez JA

更新日期：2007-11-01 00:00:00

abstract：:In this study the effect of diabetes mellitus on atrial natriuretic peptide (ANP) receptors in streptozotocin- (STZ-) induced diabetic rat kidneys was studied. Moreover, plasma ANP concentration was evaluated in diabetic and control rats by using radioimmunoassay. In addition, the expression of ANP in the kidneys of c...

journal_title：Molecular and cellular biochemistry

authors： Obineche EN,Adeghate E,Chandranath IS,Benedict S,Al Gafri LS,Adem A

更新日期：2004-06-01 00:00:00

abstract：:Primary cultures of skeletal muscle cells secrete plasminogen activator (PA) activity to the conditioning medium and display membrane-bound PA. Growth of these cells in culture in presence of 10(-7) M dexamethasone resulted in a marked reduction of the membranal and secreted PA activity. The hormone also reduced cytos...

journal_title：Molecular and cellular biochemistry

authors： Mayer M,Finci Z,Chaouat M,Sasson S

更新日期：1986-02-01 00:00:00

abstract：:L-Asparaginase activity reaches maximal values at the stationary phase of growth of Tetrahymena pyriformis and fluctuates upon the growth conditions and the composition of the medium. Most of the L-asparaginase activity (80%) is associated with the endoplasmic reticulum, and the remaining with the pellicles. Detergent...

journal_title：Molecular and cellular biochemistry

authors： Triantafillou DJ,Georgatsos JG,Kyriakidis DA

更新日期：1988-05-01 00:00:00

abstract：:Vascular endothelial and -smooth muscle cells have been shown to use fatty acids as substrates for oxidative phosphorylation. Endothelial cells are more vulnerable to oxidative stress than muscle cells and are prone to loose carnitine early during hypoperfusion. This has been suggested by two observations. The first i...

journal_title：Molecular and cellular biochemistry

authors： Hülsmann WC,Dubelaar ML

更新日期：1992-10-21 00:00:00

abstract：UNLABELLED:Since recent findings indicate the involvement of G-proteins in the mechanism of ischaemic preconditioning (PC), the present study was aimed to investigate the role of adrenergic mechanisms, such as G-proteins and stimulation of adrenergic receptors, in this phenomenon. For this purpose, isolated Langendorff...

journal_title：Molecular and cellular biochemistry

authors： Ravingerová T,Pyne NJ,Parratt JR

更新日期：1995-06-07 00:00:00

abstract：:There is general agreement that the connexin43 gap junction protein is a substrate for phosphorylation by protein kinase C but there is no similar consensus regarding the action of protein kinase A. Our previous studies demonstrated that channels formed by connexin43 were reversibly gated in response to microinjected ...

journal_title：Molecular and cellular biochemistry

authors： Shah MM,Martinez AM,Fletcher WH

更新日期：2002-09-01 00:00:00

abstract：:Recruitment of the brown-like phenotype in white adipocytes (browning) and activation of existing brown adipocytes are currently being investigated as a means to combat obesity. Thus, a wide variety of dietary agents that contribute to browning of white adipocytes have been identified. The present study was designed t...

journal_title：Molecular and cellular biochemistry

authors： Parray HA,Yun JW

更新日期：2016-05-01 00:00:00

abstract：:The involvement of the p53 gene in apoptosis of many cell types towards y-radiation is well established. However, little information is available on the relationship between p53 status and cells' ability to undergo apoptosis following exposure to fast neutrons. The aim of this study was to characterize the apoptotic p...

journal_title：Molecular and cellular biochemistry

authors： Jee YH,Jeong WI,Kim TH,Hwang IS,Ahn MJ,Joo HG,Hong SH,Jeong KS

更新日期：2005-02-01 00:00:00

abstract：:The present paper shows that human chronic myeloid (K562) cells exposed 3 h to 20 microM 3'-azido-3'-deoxythymidine (AZT) exhibit marked variations of the oligosaccharide moiety of glycoconjugates. These changes were analyzed by confocal fluorescence microscopy, upon incubation of control and AZT-treated cells with bi...

journal_title：Molecular and cellular biochemistry

authors： Lizzi AR,D'Alessandro AM,Bozzi A,Cinque B,Oratore A,D'Andrea G

更新日期：2007-06-01 00:00:00