Trolox-induced cardiac differentiation is mediated by the inhibition of Wnt/β-catenin signaling in human embryonic stem cells.

abstract：:Increasing potassium chloride concentration from 0 to 100 mM and magnesium chloride from 0 to 2 mM show a parallel rate increase in polymerizing actin, whereas increasing calcium chloride concentration from 0 to 0.2 mM decreases the rate of polymerizing actin. The presence of alpha-actinin has little influence on the ...

journal_title：Cell biology international

authors： Goldmann WH

更新日期：2002-01-01 00:00:00

abstract：:Peroxisomicine A1 (PA1) is a potential antineoplastic agent with high and selective toxicity toward peroxisomes of tumor cells. Pexophagy is a selective autophagy process that degrades damaged peroxisomes; this process has been studied mainly in methylotrophic yeasts. There are two main modes of pexophagy in yeast: ma...

journal_title：Cell biology international

authors： Ortega-Martínez M,Gutiérrez-Dávila V,Niderhauser-García A,Salazar-Aranda R,Solís-Soto JM,Montes-de-Oca-Luna R,Jaramillo-Rangel G

更新日期：2020-03-01 00:00:00

abstract：:Inner ear cells, including hair cells, spiral ganglion cells, stria vascularis cells and supporting cells on the basilar membrane, play a major role in transducing hearing signals and regulating inner ear homoeostasis. However, their functions are often damaged by antibiotic-induced ototoxicity. Apoptosis is probably ...

journal_title：Cell biology international

authors： Yu L,Tang H,Jiang XH,Tsang LL,Chung YW,Chan HC

更新日期：2010-12-01 00:00:00

abstract：:The objective of this study was to test the hypothesis that cytoskeletal actin fragmentation is mediated through caspase-2, specifically examining the ability of a caspase-2 inhibitor to interfere with actin fragmentation, in comparison with a caspase-3 inhibitor. Cardiomyocytes were cultured from embryonic chick hear...

journal_title：Cell biology international

authors： Kong JY,Rabkin SW

更新日期：2004-01-01 00:00:00

abstract：:Hypoxia is a condition in which the whole body or a region of the body is deprived of oxygen supply. The brain is very sensitive to the lack of oxygen and cerebral hypoxia can rapidly cause severe brain damage. Astrocytes are essential for the survival and function of neurons. Therefore, protecting astrocytes against ...

journal_title：Cell biology international

authors： Kang YW,Kim YS,Park JY,Chu GE,Yang YC,Choi BY,Cho WG

更新日期：2020-06-01 00:00:00

abstract：:Earlier, we have shown that spontaneously isolated non-pathogenic bacteria Serratia grimesii and Serratia proteamaculans invade eukaryotic cells, provided that they synthesize thermolysin-like metalloproteases ECP32/grimelysin or protealysin characterized by high specificity towards actin. To address the question of w...

journal_title：Cell biology international

authors： Bozhokina ES,Tsaplina OA,Efremova TN,Kever LV,Demidyuk IV,Kostrov SV,Adam T,Komissarchik YY,Khaitlina SY

更新日期：2011-02-01 00:00:00

abstract：:Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a key enzyme of the glycolytic pathway. Recent studies have demonstrated an additional role in apoptosis: GAPDH is targeted to the nucleus during apoptotic signalling. This nuclear transport has also been observed in serum-depleted cells, but it is reversible in fibr...

journal_title：Cell biology international

authors： Schmitz HD,Dutiné C,Bereiter-Hahn J

更新日期：2003-01-01 00:00:00

abstract：:Metallothionein (MT), a cysteine-rich, metal-binding protein, is involved in homeostatic regulation of essential metals and protection of cells against oxidative injury. It has been shown that oxidative stress is associated with pathogenesis of osteoporosis and is capable of inhibiting osteoblastic differentiation of ...

journal_title：Cell biology international

authors： Liu AL,Zhang ZM,Zhu BF,Liao ZH,Liu Z

更新日期：2004-01-01 00:00:00

abstract：:The focal adhesion protein vinculin has been implicated in associating with soluble and membranous phospholipids. Detailed investigations over the past ten years describe the intermolecular interactions of the vinculin tail domain with soluble and membrane phospholipids. Previous studies have implied that the tail's u...

journal_title：Cell biology international

authors： Goldmann WH

更新日期：2018-08-01 00:00:00

abstract：:Non-specific L-type calcium channel blockers, such as verapamil (> or =50 microM), induce metaphase-II (M-II) arrest and apoptosis in aged rat eggs cultured in Ca(2+)-deficient medium. However, the effects of extracellular Ca(2+) on verapamil-induced M-II arrest and apoptosis have not yet been reported. We have demons...

journal_title：Cell biology international

authors： Chaube SK,Tripathi A,Khatun S,Mishra SK,Prasad PV,Shrivastav TG

更新日期：2009-03-01 00:00:00

abstract：:Hepatic oval cells are likely to be activated during advanced stage of liver fibrosis to reconstruct damaged hepatic tissue. However, their scarcity, difficulties in isolation, and in vitro expansion hampered their transplantation in fibrotic liver. This study was aimed to investigate the repair potential of in vitro ...

journal_title：Cell biology international

authors： Awan SJ,Baig MT,Yaqub F,Tayyeb A,Ali G

更新日期：2017-01-01 00:00:00

abstract：:Reactive oxygen species (ROS) are not only generated in conditions of cellular stress but are also constitutively produced in most cell types by specific metabolic processes. This research focused on a potential antioxidant Trolox (model compound for alpha-tocopherol), with the aim to establish exact mechanisms of Tro...

journal_title：Cell biology international

authors： Raspor P,Plesnicar S,Gazdag Z,Pesti M,Miklavcic M,Lah B,Logar-Marinsek R,Poljsak B

更新日期：2005-01-01 00:00:00

abstract：:A line of evidences have validated that multiple microRNAs (including miR-16, miR-483 and miR-324-3p) were abnormally expressed in granulosa cells, which may be closely related with the pathogenesis of polycystic ovary syndrome (PCOS). Long-chain non-coding RNA (lncRNA) nuclear paraspeckle assembly transcript 1 (NEAT1...

journal_title：Cell biology international

authors： Sang X,Zhang Y

更新日期：2020-03-28 00:00:00

abstract：:microRNAs (miRNAs), through negatively regulating their target genes, influence the development and progression of many cancers. Previously, we found miR-483 was overexpressed in esophageal squamous cell carcinoma (ESCC) tissues, and its overexpression was negatively correlated with the prognosis and positively correl...

journal_title：Cell biology international

authors： Ma J,Hong L,Xu G,Hao J,Wang R,Guo H,Liu J,Zhang Y,Nie Y,Fan D

更新日期：2016-04-01 00:00:00

abstract：:Fatty liver disease is a disease manifested with excessive alcohol intake and obese. Importantly, hydrogen sulfide (H2 S) has been revealed to participate in the progression of fatty liver; however, the underlying mechanism has not been clearly elucidated yet. In this study, we aimed to investigate the effects of exog...

journal_title：Cell biology international

authors： Ruan Z,Liang M,Deng X,Lai M,Shang L,Su X

更新日期：2019-09-04 00:00:00

abstract：:To better treat patients with non-small cell lung cancer (NSCLC), the investigations on novel molecules affecting NSCLC progression are of vital importance. Long noncoding RNAs (lncRNAs) are identified as pivotal regulators that can affect the cellular activities of carcinomas. Long intergenic non-protein coding RNA 6...

journal_title：Cell biology international

authors： Yang H,Yang W,Dai W,Ma Y,Zhang G

更新日期：2020-08-01 00:00:00

abstract：:The plasticity of human and murine bone marrow mesenchymal stem cells (BMSCs) has been proven by their ability to trans-differentiate to multilineage cells, including germ cells. We have investigated ability of goat BMSCs to trans-differentiate to germ cells with extrinsic (e.g., retinoic acid [RA] and BMP4 signalling...

journal_title：Cell biology international

authors： Yan G,Fan Y,Li P,Zhang Y,Wang F

更新日期：2015-01-01 00:00:00

abstract：:The spreading behaviour of dissociated hypoblast cells on and besides a band of aligned fibrils associated with the basal lamina of the epiblast was investigated by the use of scanning electron microscopy. A horse-shaped band of aligned fibrils, first demonstrated by Wakely and England (1979), is present during the ga...

journal_title：Cell biology international

authors： Andries L,Harrisson F,Vakaet L

更新日期：1994-07-01 00:00:00

abstract：:Oral squamous cell carcinoma (OSCC) is a serious global health problem. Recently, accumulating microRNA (miRNA) has emerged as crucial players in the development and progression of carcinomas including OSCC. Our study aimed to further investigate the roles of miR-140-5p in OSCC tumorigenesis and related molecular basi...

journal_title：Cell biology international

authors： Peng M,Pang C

更新日期：2019-08-08 00:00:00

abstract：:Insulin resistance (IR) is a hallmark of type 2 diabetes mellitus (T2DM). This study aimed to explore the effects of rapamycin, a specific inhibitor of kinase mammalian target of rapamycin (mTOR), on IR in T2DM rats, and to validate whether the underlying mechanism was associated with autophagy. In this study, the mod...

journal_title：Cell biology international

authors： Zhou W,Ye S

更新日期：2018-09-01 00:00:00

abstract：:Transplanted tumours could modify the intensity and temporal distribution of the cellular proliferation in normal cell populations, and partial hepatectomy alters the serum concentrations of substances involved in cellular proliferation, leading to the compensatory liver hyperplasia. The following experiments were des...

journal_title：Cell biology international

authors： García MN,Andrini LB,Inda AM,Ronderos JR,Hijano JC,Errecalde AL

更新日期：2010-02-05 00:00:00

abstract：:The intranucleolar chromatin has been detected by feeding HeLa cells with bromodeoxyuridine and then using an immunocytochemical technique for its detection at the ultrastructural level. Labelling was mainly observed on the dense fibrillar component (DFC), which surrounds the fibrillar centres (FC). Labelling could al...

journal_title：Cell biology international

authors： Ghosh S,Paweletz N

更新日期：1998-01-01 00:00:00

abstract：:Adipose tissue is a potential site of retinoic acid (RA) action, but its physiological significance remains to be clarified. We have examined the effect of all-trans retinoic acid (ATRA) on growth and differentiation of preadipocytes, and on adipokine gene expression in mature adipocytes using human preadipocyte cell ...

journal_title：Cell biology international

authors： Morikawa K,Hanada H,Hirota K,Nonaka M,Ikeda C

更新日期：2013-01-01 00:00:00

abstract：:Endothelial progenitor cells (EPCs) are precursor cells of vascular endothelial cells, which are widely involved in the pathological process of cardiovascular diseases. EPCs apoptosis could accelerate the process of cardiovascular diseases. 14-3-3-η protein has been proved to be a potent antiapoptosis molecule. Howeve...

journal_title：Cell biology international

authors： Li Y,Sun X,Zhang X,Zhou H,Wang D,Xia Y,Li X

更新日期：2020-12-15 00:00:00

abstract：:Hepatocellular carcinoma (HCC) causes death mainly by disseminated metastasis progression from the organ being confined. Different metastatic stages are closely related to cellular metabolic profiles. Normal hepatocyte and HepG2 cell line from low metastatic HCC were studied by NMR-based metabolomic techniques. Multiv...

journal_title：Cell biology international

authors： Chen Y,Chen Z,Feng JH,Chen YB,Liao NS,Su Y,Zou CY

更新日期：2018-04-01 00:00:00

abstract：:While much evidence indicates a high degree of spatial organization in the nucleus, the underlying molecular structures that support it remain poorly characterized. By extracting with high concentrations of RNase A in a modification of the sequential extraction protocol of Penman, we have identified a novel intranucle...

journal_title：Cell biology international

authors： Padros MR,Giles DM,Suarez MD

更新日期：1997-06-01 00:00:00

abstract：:Treatment of cultured rat osteoblasts with staurosporine caused a rapid outgrowth of long slender cellular processes and the formation of stellate cells. The number of stellate cells increased with higher concentrations of and longer incubation with staurosporine. Scanning electron microscopy (SEM) revealed that the s...

journal_title：Cell biology international

authors： Yang RS,Lu KS,Fu WM,Liu TK,Lin-Shiau SY

更新日期：1993-01-01 00:00:00

abstract：:Retinoic acid (RA) and oleanolic acid (OA) were studied about their potential to induce mouse embryonic stem cell R1/E (MESC-R1/E) to differentiate toward germ cells. Embryoid bodies (EBs) first formed from MESC-R1/E and EBs were allowed to attach to the bottoms of normal cell-culturing plate and grow. Then, different...

journal_title：Cell biology international

authors： Wan Q,Lu H,Wu LT,Liu X,Xiang JB

更新日期：2014-12-01 00:00:00

abstract：:Mutants of the methanol-utilizing yeast Pichia pastoris and the alkane-utilizing yeast Yarrowia lipolytica defective in the orthologue of UGT51 (encoding sterol glucosyltransferase) were isolated and compared. These mutants do not contain the specific ergosterol derivate, ergosterol glucoside. We observed that the P. ...

journal_title：Cell biology international

authors： Stasyk OV,Nazarko TY,Stasyk OG,Krasovska OS,Warnecke D,Nicaud JM,Cregg JM,Sibirny AA

更新日期：2003-01-01 00:00:00

abstract：:Electrotonic coupling among neurons in the vertebrate, and more specifically the mammalian, brain has now been demonstrated to exist in all major brain subdivisions and in the spinal cord. For many of these brain areas, recent studies have investigated the possibilities of modulation of that coupling by synaptically r...

journal_title：Cell biology international

authors： Hatton GI

更新日期：1998-11-01 00:00:00