Metabolic profiling of normal hepatocyte and hepatocellular carcinoma cells via 1 H nuclear magnetic resonance spectroscopy.

abstract：:Having the ability to control cell behaviour would be of great advantage in tissue engineering. One method of gaining control over cell adhesion, proliferation, guidance and differentiation is use of topography. Whilst it has be known for some time that cells can be guided by micro-topography, it is only recently beco...

journal_title：Cell biology international

authors： Dalby MJ,Riehle MO,Johnstone H,Affrossman S,Curtis AS

更新日期：2004-01-01 00:00:00

abstract：:The effects of NO in its environment may vary considerably depending on various factors. This study shows oxidative mechanism of cellular membrane alterations, which is not associated with triggering of ONOOH generation but is induced by pure NO. Our investigation examined the influence of low concentration of NO (0.1...

journal_title：Cell biology international

authors： Brzeszczynska J,Gwozdzinski K

更新日期：2008-01-01 00:00:00

abstract：:The epidermal keratinocytes express two major pairs of keratin polypeptides. One pair (K5/K14) expressed specifically in basal generative compartment and the other (K1/K10) expressed specifically in the differentiating suprabasal compartment. The switch in the expression of the keratins from proliferating to different...

journal_title：Cell biology international

authors： Rao KS,Babu KK,Gupta PD

更新日期：1996-04-01 00:00:00

abstract：:The authors examined the growth response of cardinal ligamental fibroblasts derived from patients with prolapsus uteri (HPLiF) and compared it with the response of those from control subjects (HCLiF). The growth rate during the logarithmic growth phase was not different between HPLiF and HCLiF, while the cell density ...

journal_title：Cell biology international

authors： Yamamoto M,Aoyagi M,Akazawa K,Tajima S,Yamamoto K

更新日期：1998-01-01 00:00:00

abstract：:Neuroblastoma is one of the most common solid tumours in children (8-10% of all malignancies). Over 22% of cases have N-myc amplification associated with aggressively growing neuroblastomas. Oncogene-induced sensitization of cells to apoptosis is an important mechanism for suppression of tumorigenesis. Tumour suppress...

journal_title：Cell biology international

authors： Li T,Wang L,Ke XX,Gong XY,Wan JH,Hao XW,Xu M,Xiang Z,Cui ZB,Cui H

更新日期：2012-04-01 00:00:00

abstract：:Sympathetic signaling is involved in bone homeostasis; however, the cellular and molecular mechanisms remain unknown. In this study, we found that the psychological stress mediator adrenaline inhibited osteogenic differentiation of human bone marrow-derived stem cells (hMSC) by reducing microRNA-21 (miR-21) expression...

journal_title：Cell biology international

authors： Chen D,Wang Z

更新日期：2017-01-01 00:00:00

abstract：:Epicatechin, a flavonoid belonging to the group of compounds collectively called catechins, have been reported to possess insulin-like properties. Besides their anti-diabetic properties, catechins also show growth inhibition. Since cytosolic pH (pHi) plays a role in cell proliferation and the Na/H exchanger (NHE) is t...

journal_title：Cell biology international

authors： Matteucci E,Rizvi SI,Giampietro O

更新日期：2001-01-01 00:00:00

abstract：:Induction of HO-1 protein can have both beneficial and detrimental effects for cells, including regulating proliferation and apoptosis of several tumours. We have investigated the regulation of HO-1, p38MAPK and mTOR in the context of proliferation, cell cycle events and apoptosis of oesophageal squamous cell carcinom...

journal_title：Cell biology international

authors： Hu JL,Xiao L,Li ZY,Wang Q,Chang Y,Jin Y

更新日期：2013-06-01 00:00:00

abstract：:A convenient means of measuring apoptosis is described using an automated analyzer (MF-1; Sysmex), which normally provides rapid measurement of malarial parasites. By means of this MF-1 procedure, apoptotic cells exhibited characteristic changes of light scatter (size) and fluorescence (DNA content) relating to cell s...

journal_title：Cell biology international

authors： Lertworasirikul T,Bunyaratvej A,Kubota F

更新日期：2000-01-01 00:00:00

abstract：:Investigation of the relative slowness with which trypsin detaches epithelial cells from their adhesions with a substratum suggests that the adherent surface of the cells is normally rather inaccessible to the enzyme. Trypsinisation of cells through a porous filter allowing access of the enzyme to the underside of the...

journal_title：Cell biology international

authors： Simpson K,McGrath M,Curtis A

更新日期：1993-03-01 00:00:00

abstract：:To identify the molecular basis by which nonpermissive temperature (NPT) induces cell differentiation in Sertoli TTE3 cells harboring temperature-sensitive SV40 large T-antigen, we performed global scale microarray and computational gene network analyses. In TTE3 cells, inactivation of the large T-antigen by a NPT at ...

journal_title：Cell biology international

authors： Tabuchi Y,Takasaki I,Suto A,Kondo T,Suzuki Y,Obinata M

更新日期：2007-10-01 00:00:00

abstract：:Our aim has been to elucidate the possible mechanism of CJX1, an amlodipine derivative, in the modulation of P-gp function by determining its effect on P-gp ATPase activity. Basal P-gp ATPase activity was increased by CJX1 with half-maximal activity concentration (Km) of 8.6+/-1.4 microM. Kinetic analysis indicated a ...

journal_title：Cell biology international

authors： Ji BS,He L

更新日期：2009-10-01 00:00:00

abstract：:We analysed the presence and localization of spectrin-like proteins in nuclei of various plant tissues, using several anti-erythrocyte spectrin antibodies on isolated pea nuclei and nuclei in cells. Western blots of extracted purified pea nuclei show a cross-reactive pair of bands at 220-240 kDa, typical for human ery...

journal_title：Cell biology international

authors： De Ruijter NC,Ketelaar T,Blumenthal SS,Emons AM,Schel JH

更新日期：2000-01-01 00:00:00

abstract：:To define the molecular structure of bovine lens epithelium and its anterior lens capsule, we investigated the composition of lens capsule basement membrane proteins. Immunofluorescence and immunogold techniques were used to demonstrate the presence of type I and type III collagen in the lens capsule and in primary ex...

journal_title：Cell biology international

authors： Sawhney RS

更新日期：2005-02-01 00:00:00

abstract：:The aim of this study was to obtain membrane-bound alkaline phosphatase from osteoblastic-like cells of human alveolar bone. Cells were obtained by enzymatic digestion and maintained in primary culture in osteogenic medium until subconfluence. First passage cells were cultured in the same medium and at 7, 14, and 21 d...

journal_title：Cell biology international

authors： Simão AM,Beloti MM,Rosa AL,de Oliveira PT,Granjeiro JM,Pizauro JM,Ciancaglini P

更新日期：2007-11-01 00:00:00

abstract：:vasa (vas)-related genes are members of the DEAD-box protein family and are expressed in the germ cells of many Metazoa. We cloned vasa-related genes (PpVLG, CpVLG) and other DEAD-box family related genes (PpDRH1, PpDRH2, CpDRH, AtDRHr) from the colonial parasitic rhizocephalan barnacle Polyascus polygenea, the non-co...

journal_title：Cell biology international

authors： Shukalyuk AI,Golovnina KA,Baiborodin SI,Gunbin KV,Blinov AG,Isaeva VV

更新日期：2007-02-01 00:00:00

abstract：:MMP-9 participates in tumour growth, invasion, metastasis and vascularisation. Thus, inhibition of MMP-9 may be involved in the process of tumourigenesis. We have investigated the effect of RNAi-mediated MMP-9 silencing on inhibiting invasion and migration of mouse melanoma cell B16. A specific and optimised siRNA vec...

journal_title：Cell biology international

authors： Tang ZY,Liu Y,Liu LX,Ding XY,Zhang H,Fang LQ

更新日期：2013-08-01 00:00:00

abstract：:At the end of transcardial perfusions with ice-cold physiological saline for 30 min or with isoosmotic potassium chloride for 5 min, but immediately before perfusion fixation, condenser-discharge electric shocks were administered to rats through surface electrodes pressed onto the temporal muscles of the scalped skull...

journal_title：Cell biology international

authors： Kellermayer R,Zsombok A,Auer T,Gallyas F

更新日期：2006-02-01 00:00:00

abstract：:The cytosolic lipid droplets (cLDs) store excess intracellular lipids, and perilipin-2 is believed to protect cLDs from degradation. Here, we investigated the role of the small G-protein Arf1 and the proteasome in the fates of perilipin-2 and cLDs. In oleate-loaded cells, upon brefeldin A (BFA) treatment, perilipin-2 ...

journal_title：Cell biology international

authors： Pauloin A,Adenot P,Hue-Beauvais C,Chanat E

更新日期：2016-02-01 00:00:00

abstract：:Klotho beta (Klb), a single-pass transmembrane protein, has been described as a co-receptor for endocrine FGFs, such as FGF15/19 and FGF21, to regulate critical metabolic processes in multiple organs and tissues in adult mice. However, its function during early embryonic development remains largely unknown. In this pa...

journal_title：Cell biology international

authors： Chen G,Tao Q

更新日期：2019-02-01 00:00:00

abstract：:The effect of piperine on the fertilization of eggs with sperm was investigated in female hamsters. They were intragastrically treated with piperine at doses of 50 and 100 mg/kg BW from day 1 through day 4 of the oestrous cycle. During piperine treatment, these females were superovulated and artificially inseminated (...

journal_title：Cell biology international

authors： Piyachaturawat P,Pholpramool C

更新日期：1997-07-01 00:00:00

abstract：:Several synthetic decapeptides containing an HAV tripeptide motif were tested for their ability to modulate the enzymatic activity of rat extracellular SOD, an enzyme which also contains an HAV motif. Out of nine decapeptides that were tested, only a FGF-receptor derived peptide was active as a negative modulator of e...

journal_title：Cell biology international

authors： Willems J,Noppe W,Slegers H

更新日期：1995-11-01 00:00:00

abstract：:Normal human bone marrow stroma cells include stem cells for both haemopoietic and osteochondrogenic lineages and express both bone morphogenetic protein (BMP) type I and type II receptors. As a member of the TGF-beta super-family, BMP-6 binds to both BMP type I and type II receptors and is involved in the development...

journal_title：Cell biology international

authors： Ahmed N,Sammons J,Carson RJ,Khokher MA,Hassan HT

更新日期：2001-01-01 00:00:00

abstract：:A significant decrease in tissue pH or acidosis is a common feature of numerous diseases, including RA (rheumatoid arthritis). Cartilage homoeostasis is profoundly affected by local acidosis in the joints. The diuretic, amiloride, is neuroprotective in models of cerebral ischaemia, a property attributable to the inhib...

journal_title：Cell biology international

authors： Rong C,Chen FH,Jiang S,Hu W,Wu FR,Chen TY,Yuan FL

更新日期：2012-07-01 00:00:00

abstract：:MicroRNAs (miRNAs) play an increasingly important role in cancer growth by coordinately suppressing genes that control cell migration, proliferation, and invasion. The above results can be achieved through the regulation of gene expression by miRNAs by suppressing translation or the direct sequence-specific degradatio...

journal_title：Cell biology international

authors： Sun M,Wang X,Tu C,Wang S,Qu J,Xiao S

更新日期：2017-12-01 00:00:00

abstract：:There is increasing evidence that the expression level of drug metabolic enzymes affects the final cellular response following drug treatment. Moreover, anti-tumour agents may modulate enzymatic activity and/or cellular expression of metabolic enzymes in tumour cells. We have investigated the influence of CYP3A4 overe...

journal_title：Cell biology international

authors： Augustin E,Pawłowska M,Polewska J,Potega A,Mazerska Z

更新日期：2013-02-01 00:00:00

abstract：:Hypoxia alters the biological functions of skeletal muscle cells to proliferate and differentiate into myotubes. However, the cellular responses of myoblasts to hypoxia differ according to the levels of oxygen and the types of cells studied. This study examined the effect of hypoxia (1% oxygen) on bovine satellite cel...

journal_title：Cell biology international

authors： Kook SH,Son YO,Lee KY,Lee HJ,Chung WT,Choi KC,Lee JC

更新日期：2008-08-01 00:00:00

abstract：:Prolapsus uteri in pelvic supportive disorders are common in elderly women, and their etiology remains unclear. We examined elastin-binding proteins (EBPs) and binding sites in cultured cardinal ligament fibroblasts derived from elderly patients with prolapsus uteri (HPLiF) and compared them with those from age-matche...

journal_title：Cell biology international

authors： Yamamoto M,Akazawa K,Aoyagi M,Yamamoto N,Yamamoto K

更新日期：2002-01-01 00:00:00

abstract：:The aim of this study was to examine the effects of glafenine hydrochloride (a nonsteroidal anti-inflammatory drug) on proliferation, clonogenic activity, cell-cycle, migration, and the extracellular matrix protein tenascin of human aortic smooth muscle cells (haSMCs) and human endothelial cells (ECs) in vitro.HaSMCs ...

journal_title：Cell biology international

authors： Schöber W,Tran QB,Muringaseril M,Wiskirchen J,Kehlbach R,Rodegerdts E,Wiesinger B,Claussen CD,Duda SH

更新日期：2003-01-01 00:00:00

abstract：:Insulin resistance, diabetes and many kinds of cancers are common in overweight and obese individuals. The tumor suppressor p53 is important in securing genetic stability, but its role in the regulation of metabolic processes and cell differentiation remains unclear. We have investigated the role of p53 in adipocyte d...

journal_title：Cell biology international

authors： Huang Q,Liu M,Du X,Zhang R,Xue Y,Zhang Y,Zhu W,Li D,Zhao A,Liu Y

更新日期：2014-12-01 00:00:00