Pancreatic human islets and insulin-producing cells derived from embryonic stem cells are rapidly identified by a newly developed Dithizone.

abstract：:Worldwide, Bartonella infections are known to inflict a wide range of mammals and, within rodents alone, more than 20 Bartonella species have been detected. There is, however, a lack of studies on the presence of Bartonella spp. in rodents in the Baltic region. We analysed 580 individuals belonging to eight small rode...

journal_title：Scientific reports

authors： Mardosaitė-Busaitienė D,Radzijevskaja J,Balčiauskas L,Bratchikov M,Jurgelevičius V,Paulauskas A

更新日期：2019-08-26 00:00:00

abstract：:A detailed molecular understanding of botulinum neurotoxin (BoNT)/host-cell-receptor interactions is fundamental both for developing strategies against botulism and for generating improved BoNT variants for medical applications. The X-ray crystal structure of the receptor-binding domain (HC) of BoNT/A1 in complex with...

journal_title：Scientific reports

authors： Benoit RM,Schärer MA,Wieser MM,Li X,Frey D,Kammerer RA

更新日期：2017-03-02 00:00:00

abstract：:Desorption electrospray ionisation-mass spectrometry imaging (DESI-MSI) is a powerful imaging technique for the analysis of complex surfaces. However, the often highly complex nature of biological samples is particularly challenging for MSI approaches, as options to appropriately address molecular complexity are limit...

journal_title：Scientific reports

authors： Kooijman PC,Nagornov KO,Kozhinov AN,Kilgour DPA,Tsybin YO,Heeren RMA,Ellis SR

更新日期：2019-01-09 00:00:00

abstract：:We evaluated bioactive glass graft (S53P4) in patients undergoing Le Fort I osteotomy, with non-grafted patients as controls. Computed tomography facial scans of the 25 patients submitted for Le Fort I were divided into two groups: Group 1-S53P4 group and Group 2-without grafting. CT scans were analyzed in the immedia...

journal_title：Scientific reports

authors： de Souza Cruz EL,de Souza FJ Jr,de Menezes LM,Tuji FM,Carneiro JT Jr

更新日期：2020-07-29 00:00:00

abstract：:Polysialic acid (PSA) is a large negatively charged glycan mainly attached to the neural cell adhesion molecule (NCAM). Several studies have shown that it is important for correct formation of brain circuitries during development and for synaptic plasticity, learning and memory in the adult. PSA also plays a major rol...

journal_title：Scientific reports

authors： Saini V,Lutz D,Kataria H,Kaur G,Schachner M,Loers G

更新日期：2016-06-21 00:00:00

abstract：:Infestation by the biotrophic pathogen Gymnosporangium asiaticum can be devastating for plant of the family Rosaceae. However, the phytopathology of this process has not been thoroughly elucidated. Using a metabolomics approach, we discovered the intrinsic activities that induce disease symptoms after fungal invasion ...

journal_title：Scientific reports

authors： Lee DK,Ahn S,Cho HY,Yun HY,Park JH,Lim J,Lee J,Kwon SW

更新日期：2016-11-28 00:00:00

abstract：:Surface plasmon polaritons (SPPs) and standing wave modes provide interesting and exotic properties for infrared metamaterial absorbers. Coupling of these modes promises further development in this field but restricted by the complexity of modes analysis. In this work, we investigate the general phenomenon of modes co...

journal_title：Scientific reports

authors： Zhen G,Zhou P,Luo X,Xie J,Deng L

更新日期：2017-04-11 00:00:00

abstract：:Here we present the first report of a carbon-γ-Fe₂O₃ nanoparticle composite of mesoporous carbon, bearing COOH- and phenolic OH- functional groups on its surface, a remarkable and magnetically separable adsorbent, for the radioactive material emitted by the Fukushima Daiichi nuclear power plant accident. Contaminated ...

journal_title：Scientific reports

authors： Yamaguchi D,Furukawa K,Takasuga M,Watanabe K

更新日期：2014-08-13 00:00:00

abstract：:Immune checkpoint inhibitors (ICIs) elicit antitumour effects by activating the host immunity and cause immune-related adverse events (irAEs). ICI-related interstitial lung disease (ICI-ILD) is a fatal irAE that is difficult to treat; moreover, its incidence is relatively higher in patients with lung cancer. Therefore...

journal_title：Scientific reports

authors： Okada N,Matsuoka R,Sakurada T,Goda M,Chuma M,Yagi K,Zamami Y,Nishioka Y,Ishizawa K

更新日期：2020-08-13 00:00:00

abstract：:Psoriasis is a chronic, relapsing inflammatory skin disease. The pathogenesis of psoriasis is complex and has not been fully understood. C10orf99 was a recently identified human antimicrobial peptide whose mRNA expression is elevated in psoriatic human skin samples. In this study, we investigated the functional roles ...

journal_title：Scientific reports

authors： Chen C,Wu N,Duan Q,Yang H,Wang X,Yang P,Zhang M,Liu J,Liu Z,Shao Y,Zheng Y

更新日期：2018-06-05 00:00:00

abstract：:The objective of this study was to evaluate the stimulatory effects of Bacillus amyloliquefaciens SQR9 on dendritic cells (DCs) and to verify its ability to enhance the immune response by modulating DC maturation. The results demonstrated that B. amyloliquefaciens SQR9 can adhere to the nasal epithelium and be taken u...

journal_title：Scientific reports

authors： Huang L,Qin T,Yin Y,Gao X,Lin J,Yang Q,Yu Q

更新日期：2016-02-19 00:00:00

abstract：:Although it is clear that lipids are responsible for insulin resistance, it is poorly understood what types of lipids are involved. In this study, we verified the characteristic lipid species in skeletal muscle of a chronic exercise training model and a high-fat induced-obesity model. Three different lipidomics analys...

journal_title：Scientific reports

authors： Goto-Inoue N,Yamada K,Inagaki A,Furuichi Y,Ogino S,Manabe Y,Setou M,Fujii NL

更新日期：2013-11-20 00:00:00

abstract：:The nitrogen-vacancy (NV) centre in diamond is a promising candidate for quantum computing applications and magnetic sensing applications, because it is an atomic-scale defect with stable coherence time (T2) and reliable accessibility at room temperature. We demonstrated a method for improving the NV spin properties (...

journal_title：Scientific reports

authors： Brandenburg F,Nagumo R,Saichi K,Tahara K,Iwasaki T,Hatano M,Jelezko F,Igarashi R,Yatsui T

更新日期：2018-10-26 00:00:00

abstract：:Contamination by endocrine disrupting compounds (EDCs) concerns the security and sustainability of a drinking water supply system and human exposure via water consumption. This study analyzed the selected EDCs in source (river water, n = 10) and supply (tap water, n = 155) points and the associated risks. A total of 1...

journal_title：Scientific reports

authors： Wee SY,Aris AZ,Yusoff FM,Praveena SM

更新日期：2020-10-20 00:00:00

abstract：:Ghrelin is the only orexigenic peptide currently known and a potent prokinetic by promoting gastric motility but novel insights suggest that its role extends beyond satiety regulation. Whereas ghrelin was shown to provide somatic and colonic antinociception, its impact on gastric sensitivity is unknown even though sto...

journal_title：Scientific reports

authors： Meleine M,Mounien L,Atmani K,Ouelaa W,Bôle-Feysot C,Guérin C,Depoortere I,Gourcerol G

更新日期：2020-06-19 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML version of this paper. The error has been fixed in the paper. ...

journal_title：Scientific reports

authors： Bauer S,Wennberg Huldt C,Kanebratt KP,Durieux I,Gunne D,Andersson S,Ewart L,Haynes WG,Maschmeyer I,Winter A,Ämmälä C,Marx U,Andersson TB

更新日期：2018-01-23 00:00:00

abstract：:Circular RNA (circRNA) is a newly discovered non-coding RNA, which play significant roles in the function and transcriptional regulation of microRNA. To date, in Chinese cabbage, the functional characteristic of circRNAs in response to calcium deficiency-induced tip-burn have not been reported. In this study, 730 circ...

journal_title：Scientific reports

authors： Wang W,Wang J,Wei Q,Li B,Zhong X,Hu T,Hu H,Bao C

更新日期：2019-10-10 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： de Barsy M,Herrgott L,Martin V,Pillonel T,Viollier PH,Greub G

更新日期：2019-11-05 00:00:00

abstract：:We present a table-top beamline providing a soft X-ray supercontinuum extending up to 370 eV from high-order harmonic generation with sub-13 fs 1300 nm driving pulses and simultaneous production of sub-5 fs pulses centered at 800 nm. Optimization of high harmonic generation in a long and dense gas medium yields a phot...

journal_title：Scientific reports

authors： Barreau L,Ross AD,Garg S,Kraus PM,Neumark DM,Leone SR

更新日期：2020-04-01 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) patients are at higher risk of developing lung cancer and its metastasis, but no suitable biomarker has been reported for differential diagnosis of these patients. Levels of serum biomarkers (VEGF, IL-8, MMP-9 and MMP-2) were analyzed in these patients, which were compared ...

journal_title：Scientific reports

authors： Balla MM,Desai S,Purwar P,Kumar A,Bhandarkar P,Shejul YK,Pramesh CS,Laskar S,Pandey BN

更新日期：2016-11-04 00:00:00

abstract：:The macular ellipsoid zone intensity (mEZi) is a known marker of disease severity in a number of diverse ocular diseases. The purpose of this study was to establish an automated method (AM) for mEZi quantification and to compare the method's performance with that of a manual method (MM) for glaucoma patients and healt...

journal_title：Scientific reports

authors： Ha A,Sun S,Kim YK,Jeoung JW,Kim HC,Park KH

更新日期：2019-12-24 00:00:00

abstract：:Loss of anorectal resting pressure due to internal anal sphincter (IAS) dysfunctionality causes uncontrolled fecal soiling and leads to passive fecal incontinence (FI). The study is focused on immediate and long-term safety and potential efficacy of bioengineered IAS BioSphincters to treat passive FI in a clinically r...

journal_title：Scientific reports

authors： Dadhich P,Bohl JL,Tamburrini R,Zakhem E,Scott C,Kock N,Mitchell E,Gilliam J,Bitar KN

更新日期：2019-12-02 00:00:00

abstract：:Small bowel capsule endoscopy (SBCE) and balloon-assisted endoscopy (BAE) have revolutionized the diagnosis and treatment of small bowel bleeding (SBB), allowing access to the small bowel and identification of specific bleeding lesions. However, some patients experience rebleeding after small bowel investigation, and ...

journal_title：Scientific reports

authors： Uchida G,Hirooka Y,Nakamura M,Watanabe O,Yamamura T,Matsushita M,Suhara H,Ishikawa T,Furukawa K,Funasaka K,Ohno E,Kawashima H,Miyahara R,Goto H

更新日期：2018-04-23 00:00:00

abstract：:This paper reports a facile and green method for conversion of graphene oxide (GO) into graphene by low-temperature heating (80 °C) in the presence of a glass wafer. Compared to conventional GO chemical reduction methods, the presented approach is easy-scalable, operationally simple, and based on the use of a non-toxi...

journal_title：Scientific reports

authors： Rabchinskii MK,Dideikin AT,Kirilenko DA,Baidakova MV,Shnitov VV,Roth F,Konyakhin SV,Besedina NA,Pavlov SI,Kuricyn RA,Lebedeva NM,Brunkov PN,Vul' AY

更新日期：2018-09-20 00:00:00

abstract：:MicroRNA-200 (miR-200) family is highly expressed in ovarian cancer. We evaluated the levels of family members relative to the internal control miR-103a in ovarian cancer and control blood specimens collected from American and Hong Kong Chinese institutions, as well as from a laying hen spontaneous ovarian cancer mode...

journal_title：Scientific reports

authors： Choi PW,Bahrampour A,Ng SK,Liu SK,Qiu W,Xie F,Kuo WP,Kwong J,Hales KH,Hales DB,Wong KK,Norwitz ER,Chow CK,Berkowitz RS,Ng SW

更新日期：2020-11-18 00:00:00

abstract：:Atomic force microscope (AFM) based single molecule force spectroscopy (SMFS) and a quartz crystal microbalance (QCM) were respectively employed to probe interfacial characteristics of fibronectin fragment FNIII8-14 and full-length fibronectin (FN) on CH3-, OH-, COOH-, and NH2-terminated alkane-thiol self-assembled mo...

journal_title：Scientific reports

authors： Liamas E,Black RA,Mulheran PA,Tampé R,Wieneke R,Thomas ORT,Zhang ZJ

更新日期：2020-09-24 00:00:00

abstract：:Random lasers consisting of slab waveguides with two-dimensional disordered wrinkling patterns that act as scattering resonators are reported. As active material 2,2',7,7'-tetraphenyl-9,9'-spirobifluorene is used which is sandwiched between an oxidized silicon wafer and a cladding with higher glass transition temperat...

journal_title：Scientific reports

authors： Hoinka NM,Ostwald C,Fuhrmann-Lieker T

更新日期：2020-02-12 00:00:00

abstract：:The hypothalamic-pituitary-adrenal (HPA) axis is an important component of neuroendocrine stress regulation and coping behavior. Transcriptome profiles of the hypothalamus and adrenal gland were assessed to identify molecular pathways and candidate genes for coping behavior in pigs. Ten each of high- (HR) and low- (LR...

journal_title：Scientific reports

authors： Gley K,Murani E,Trakooljul N,Zebunke M,Puppe B,Wimmers K,Ponsuksili S

更新日期：2019-09-10 00:00:00

abstract：:The determinants of Xpert MTB/RIF sensitivity, a widely used PCR test for the diagnosis of tuberculosis (TB) are poorly understood. We compared culture time-to-positivity (TTP; a surrogate of bacterial load), MTB/RIF TB-specific and internal positive control (IPC)-specific C(T) values, and clinical characteristics in ...

journal_title：Scientific reports

authors： Theron G,Peter J,Calligaro G,Meldau R,Hanrahan C,Khalfey H,Matinyenya B,Muchinga T,Smith L,Pandie S,Lenders L,Patel V,Mayosi BM,Dheda K

更新日期：2014-07-11 00:00:00

abstract：:Transport of tissue-derived lymphatic fluid and clearance by draining lymph nodes are pivotal for maintenance of fluid homeostasis in the body and for immune-surveillance of the self- and non-self-proteomes. Yet a quantitative analysis of nodal filtration of the tissue-derived proteome present in lymphatic fluid has n...

journal_title：Scientific reports

authors： Clement CC,Wang W,Dzieciatkowska M,Cortese M,Hansen KC,Becerra A,Thangaswamy S,Nizamutdinova I,Moon JY,Stern LJ,Gashev AA,Zawieja D,Santambrogio L

更新日期：2018-07-26 00:00:00