Publisher Correction: Functional coupling of human pancreatic islets and liver spheroids on-a-chip: Towards a novel human ex vivo type 2 diabetes model.

abstract：:A simple and scalable approach has been reported for V2O5 encapsulation over interconnected multi-walled carbon nanotubes (MWCNTs) network using chemical bath deposition method. Chemically synthesized V2O5/MWCNTs electrode exhibited excellent charge-discharge capability with extraordinary cycling retention of 93% over...

journal_title：Scientific reports

authors： Pandit B,Dubal DP,Gómez-Romero P,Kale BB,Sankapal BR

更新日期：2017-03-03 00:00:00

abstract：:The unfolded protein response (UPR) not only resolves endoplasmic reticulum (ER) stress, but also regulates cellular physiological functions. In this study, we first linked the UPR to the physiological roles of brown adipose tissue (BAT). BAT is one of the tissues that control energy homeostasis in the body. Brown adi...

journal_title：Scientific reports

authors： Asada R,Kanemoto S,Matsuhisa K,Hino K,Cui M,Cui X,Kaneko M,Imaizumi K

更新日期：2015-11-16 00:00:00

abstract：:Recently, based on space-variant Pancharatnam-Berry (PB) phases, various flat devices allowing abrupt changes of beam parameters have been predicted and demonstrated to implement intriguing manipulation on spin states in three dimensions, including the efficient generation of vector beams, spin Hall effect of light an...

journal_title：Scientific reports

authors： Li P,Guo X,Qi S,Han L,Zhang Y,Liu S,Li Y,Zhao J

更新日期：2018-06-29 00:00:00

abstract：:The study aimed to compare the tumor response to and complications of doxorubicin-eluting CalliSphere bead-transarterial chemoembolization (DEB-TACE) using small- and medium-sized beads in patients with hepatocellular carcinoma (HCC) who underwent multiple rounds of oncology therapies. Sixty patients with intermediate...

journal_title：Scientific reports

authors： Wang CY,Xia JG,Yang ZQ,Zhou WZ,Chen WH,Qi CJ,Gu JP,Wang Q

更新日期：2020-03-10 00:00:00

abstract：:Scattered and indirect evidence suggests that sea ice occurred as far south as the Iceland Sea during the Early Pliocene, when the global climate was warmer than present. However, conclusive evidence as well as potential mechanisms governing sea ice occurrence outside the Arctic Ocean during a time with elevated green...

journal_title：Scientific reports

authors： Clotten C,Stein R,Fahl K,Schreck M,Risebrobakken B,De Schepper S

更新日期：2019-01-30 00:00:00

abstract：:We report improvement of terahertz (THz) wave radiation for Si-based catalyst-free InAs nanowires (NWs) by simple dipping into tap water (DTW). In addition, the possibility of using InAs NWs as a cost-effective method for biomedical applications is discussed by comparison to bulk InAs. The peak-to-peak current signals...

journal_title：Scientific reports

authors： Park DW,Bin Ji Y,Hwang J,Lee CR,Lee SJ,Kim JO,Noh SK,Oh SJ,Kim SH,Jeon TI,Jeong KU,Kim JS

更新日期：2016-10-26 00:00:00

abstract：:Neuroimaging studies in social neuroscience have largely relied on functional connectivity (FC) methods to characterize the functional integration between different brain regions. However, these methods have limited utility in social-cognitive studies that aim to understand the directed information flow among brain ar...

journal_title：Scientific reports

authors： Esménio S,Soares JM,Oliveira-Silva P,Zeidman P,Razi A,Gonçalves ÓF,Friston K,Coutinho J

更新日期：2019-02-22 00:00:00

abstract：:Peritoneal fibrosis (PF) is a severe complication of peritoneal dialysis, but there are few effective therapies for it. Recent studies have revealed a new biological function of trehalose as an autophagy inducer. Thus far, there are few reports regarding the therapeutic effects of trehalose on fibrotic diseases. There...

journal_title：Scientific reports

authors： Miyake T,Sakai N,Tamai A,Sato K,Kamikawa Y,Miyagawa T,Ogura H,Yamamura Y,Oshima M,Nakagawa S,Sagara A,Shinozaki Y,Toyama T,Kitajima S,Hara A,Iwata Y,Shimizu M,Furuichi K,Kaneko S,Wada T

更新日期：2020-08-31 00:00:00

abstract：:Luminescent zeolites exchanged with two distinct and interacted emissive ions are vital but less-studied for the potential applications in white light emitting diodes, solar cells, optical codes, biomedicine and so on. Typical transition metal ion Mn2+ and lanthanide ion Yb3+ are adopted as a case study via their char...

journal_title：Scientific reports

authors： Ye S,Sun J,Yi X,Wang Y,Zhang Q

更新日期：2017-04-10 00:00:00

abstract：:Tetrandrine (Tet) could enhance the antitumor effect of Paclitaxel (Ptx) by increasing intracellular Reactive Oxygen Species (ROS) levels, which leads to the possibility of co-delivery of both drugs for synergistic antitumor effect. In the current study, we reported an efficient, local therapeutic strategy employing e...

journal_title：Scientific reports

authors： Zhang H,Tian Y,Zhu Z,Xu H,Li X,Zheng D,Sun W

更新日期：2016-05-26 00:00:00

abstract：:Predictive coding theory suggests that predictable responses are "explained away" (i.e., reduced) by feedback. Experimental evidence for feedback inhibition, however, is inconsistent: most neuroimaging studies show reduced activity by predictive feedback, while neurophysiology indicates that most inter-areal cortical ...

journal_title：Scientific reports

authors： Han B,VanRullen R

更新日期：2016-03-14 00:00:00

abstract：:Emerging evidence demonstrates the importance of sufficient vitamin D (1α, 25-dihydroxyvitamin D3) levels during early life stage development with deficiencies associated with long-term effects into adulthood. While vitamin D has traditionally been associated with mineral ion homeostasis, accumulating evidence suggest...

journal_title：Scientific reports

authors： Knuth MM,Mahapatra D,Jima D,Wan D,Hammock BD,Law M,Kullman SW

更新日期：2020-09-29 00:00:00

abstract：:Adolescent idiopathic scoliosis (AIS) patients have been reported to be taller and more slender than normal controls, suggesting less mechanical stiffness of their trunk and spine. For assessment of mechanical stiffness, to our best knowledge this is the first to study height-width-depth relations at the level of the ...

journal_title：Scientific reports

authors： Chen H,Schlösser TPC,Brink RC,Colo D,van Stralen M,Shi L,Chu WCW,Heng PA,Castelein RM,Cheng JCY

更新日期：2017-04-18 00:00:00

abstract：:Recent studies showed that anomalous dry conditions and limited moisture supply roughly between 1998 and 2008, especially in the Southern Hemisphere, led to reduced vegetation productivity and ceased growth in land evapotranspiration (ET). However, natural variability of Earth's climate system can degrade capabilities...

journal_title：Scientific reports

authors： Zhang K,Kimball JS,Nemani RR,Running SW,Hong Y,Gourley JJ,Yu Z

更新日期：2015-10-30 00:00:00

abstract：:Glomerular filtration rate (GFR) and urinary albumin excretion rate (UAER) are used to diagnose and classify the severity of chronic kidney disease. Total adiponectin (T-AN) and high molecular weight adiponectin (H-AN) assays were developed using the fully automated immunoassay system, HI-1000 and their significance o...

journal_title：Scientific reports

authors： Watanabe T,Fujimoto Y,Morimoto A,Nishiyama M,Kawai A,Okada S,Aiba M,Kawano T,Kawahigashi M,Ishizu M,Mori H,Matsuhisa M,Hata A,Funaki M,Hashida S

更新日期：2020-09-28 00:00:00

abstract：:Carbon quantum dots (C-QDs) are becoming a desirable alternative to metal-based QDs and dye probes owing to their high biocompatibility, low toxicity, ease of preparation, and unique photophysical properties. Herein, we describe fluorescence bioimaging of zebrafish using C-QDs as probe in terms of the preparation of C...

journal_title：Scientific reports

authors： Kang YF,Li YH,Fang YW,Xu Y,Wei XM,Yin XB

更新日期：2015-07-02 00:00:00

abstract：:The DNA methyltransferase DNMT3A R882H mutation is observed in 25% of all AML patients. DNMT3A is active as tetramer and the R882H mutation is located in one of the subunit/subunit interfaces. Previous work has reported that formation of mixed wildtype/R882H complexes leads to a strong loss of catalytic activity obser...

journal_title：Scientific reports

authors： Emperle M,Dukatz M,Kunert S,Holzer K,Rajavelu A,Jurkowska RZ,Jeltsch A

更新日期：2018-09-05 00:00:00

abstract：:In April 2012 we carried out a 1-year hematological study on a population of wild Japanese monkeys inhabiting the forest area of Fukushima City. This area is located 70 km from the Fukushima Daiichi Nuclear Power Plant (NPP), which released a large amount of radioactive material into the environment following the Grea...

journal_title：Scientific reports

authors： Ochiai K,Hayama S,Nakiri S,Nakanishi S,Ishii N,Uno T,Kato T,Konno F,Kawamoto Y,Tsuchida S,Omi T

更新日期：2014-07-24 00:00:00

abstract：:Based on an inverted bulk band order, antimony thin films presumably could become topological insulators if quantum confinement effect opens up a gap in the bulk bands. Coupling between topological surface states (TSS) from opposite surfaces, however, tends to degrade or even destroy their novel characters. Here the e...

journal_title：Scientific reports

authors： Yao G,Luo Z,Pan F,Xu W,Feng YP,Wang XS

更新日期：2013-01-01 00:00:00

abstract：:Epidemiologic studies have identified a positive association between obesity and colorectal neoplasia. Adiposity induces systemic low-grade inflammation, which is commonly assessed with a sensitive biomarker, C-reactive protein (CRP). To understand the molecular mechanisms of obesity in the etiology of colorectal neop...

journal_title：Scientific reports

authors： Kigawa N,Budhathoki S,Yamaji T,Iwasaki M,Inoue M,Tsugane S

更新日期：2017-06-30 00:00:00

abstract：:Influenza virus neuraminidase (NA) is the primary target for influenza therapeutics. Severe complications are often related to secondary pneumonia caused by Streptococcus pneumoniae (pneumococci), which also express NAs. Recently, a NA-mediated lethal synergism between influenza A viruses and pneumococci was described...

journal_title：Scientific reports

authors： Grienke U,Richter M,Walther E,Hoffmann A,Kirchmair J,Makarov V,Nietzsche S,Schmidtke M,Rollinger JM

更新日期：2016-06-03 00:00:00

abstract：:Patients with liver cirrhosis are susceptible to infections with high short-term mortalities. One CD97-related EGF-TM7 molecule, EMR2 (EGF-like molecule containing mucin-like hormone receptor 2), had been shown to regulate human neutrophil function, potentiate systemic inflammation. Nevertheless, EMR2 could also suppr...

journal_title：Scientific reports

authors： Huang CH,Jeng WJ,Ho YP,Teng W,Hsieh YC,Chen WT,Chen YC,Lin HH,Sheen IS,Lin CY

更新日期：2016-12-01 00:00:00

abstract：:ABO blood group is associated with cardiovascular disease, with significantly lower risk in blood group O individuals. ABO(H) blood group determinants are expressed on different glycoproteins on platelet surfaces. In addition, ABO(H) structures are also present on VWF glycans. These ABO(H) carbohydrates influence both...

journal_title：Scientific reports

authors： O'Donghaile D,Jenkins PV,McGrath RT,Preston L,Field SP,Ward SE,O'Sullivan JM,O'Donnell JS

更新日期：2020-10-27 00:00:00

abstract：:Cell therapy using intramuscular injections of autologous bone-marrow mononuclear cells (BM-MNCs) improves clinical symptoms and can prevent limb amputation in atherosclerotic peripheral arterial disease (PAD) patients with critical limb ischemia (CLI). The purpose of this study was to evaluate the effects of the numb...

journal_title：Scientific reports

authors： Yusoff FM,Kajikawa M,Takaeko Y,Kishimoto S,Hashimoto H,Maruhashi T,Nakashima A,Wahid SFSA,Higashi Y

更新日期：2020-11-16 00:00:00

abstract：:The GacS/GacA two-component system (also called GrrS/GrrA) is a global regulatory system which is highly conserved among gamma-proteobacteria. This system positively regulates non-coding small regulatory RNA csrB, which in turn binds to the RNA-binding protein CsrA. However, how GacS/GacA-Csr system regulates virulenc...

journal_title：Scientific reports

authors： Ancona V,Lee JH,Zhao Y

更新日期：2016-11-15 00:00:00

abstract：:While is widely acknowledged that nonmuscle myosin II (NMMII) enables stress fibers (SFs) to generate traction forces against the extracellular matrix, little is known about how specific NMMII isoforms and functional domains contribute to SF mechanics. Here we combine biophotonic and genetic approaches to address thes...

journal_title：Scientific reports

authors： Chang CW,Kumar S

更新日期：2015-09-04 00:00:00

abstract：:Caspases are proteases traditionally associated with inflammation and cell death. Recently, they have also been shown to modulate cell proliferation and differentiation. The aim of the current research was to search for osteogenic molecules affected by caspase inhibition and to specify the individual caspases critical...

journal_title：Scientific reports

authors： Kratochvílová A,Veselá B,Ledvina V,Švandová E,Klepárník K,Dadáková K,Beneš P,Matalová E

更新日期：2020-05-04 00:00:00

abstract：:The prediction of drug-target interactions is a key step in the drug discovery process, which serves to identify new drugs or novel targets for existing drugs. However, experimental methods for predicting drug-target interactions are expensive and time-consuming. Therefore, the in silico prediction of drug-target inte...

journal_title：Scientific reports

authors： Kuang Q,Xu X,Li R,Dong Y,Li Y,Huang Z,Li Y,Li M

更新日期：2015-09-09 00:00:00

abstract：:Invasive non-native species have pervasive impacts on native biodiversity, including population extirpations and species extinctions. Identifying reasons why a population of a native species is extirpated following an invasion often relies on literature-based results of anecdotal observations. The well-established sch...

journal_title：Scientific reports

authors： Haubrock PJ,Balzani P,Britton JR,Haase P

更新日期：2020-12-10 00:00:00

abstract：:The number of osteoarthritis patients is increasing with the rise in the number of elderly people in developed countries. Osteoarthritis, which causes joint pain and deformity leading to loss of activities of daily living, is often treated surgically. Here we show that mechanical stress promotes accumulation of reacti...

journal_title：Scientific reports

authors： Kaneko Y,Tanigawa N,Sato Y,Kobayashi T,Nakamura S,Ito E,Soma T,Miyamoto K,Kobayashi S,Harato K,Matsumoto M,Nakamura M,Niki Y,Miyamoto T

更新日期：2019-12-10 00:00:00