Abstract:
BACKGROUND AND PURPOSE:Parkinson's disease (PD) reduces independence and quality of life through deterioration of upper limb motor function. Transcranial direct current stimulation (tDCS) may offer an alternative, adjunctive therapy for PD. However, the efficacy of tDCS for upper limb motor rehabilitation in PD is unknown. In this systematic review, evidence is compiled regarding the effects of tDCS on upper limb motor function in PD. METHODS:Studies of tDCS applied to PD patients that assessed upper limb motor function, conducted between January 2000 and November 2018, were screened for inclusion via a systematic search of Medline, Cochrane, PsycINFO, EMBASE, CINAHL, and Web of Science. RESULTS:Ten out of 606 studies were included and their findings synthesized into five categories regarding the effects of tDCS on: (1) Unified Parkinson's Disease Rating Scale motor section (UPDRS III), (2) upper limb motor tasks, (3) manual dexterity, (4) reaction time, and (5) neurophysiology. CONCLUSIONS:When applied to the primary motor cortex, tDCS may improve UPDRS III and the speed and force of movement. Considerable variation was found in tDCS parameters and further study is needed to clarify the long-term effects of tDCS on both simple and complex motor tasks and to compile relevant neurophysiological evidence.
journal_name
J Neuroljournal_title
Journal of neurologyauthors
Simpson MW,Mak Mdoi
10.1007/s00415-019-09385-ysubject
Has Abstractpub_date
2020-12-01 00:00:00pages
3479-3488issue
12eissn
0340-5354issn
1432-1459pii
10.1007/s00415-019-09385-yjournal_volume
267pub_type
杂志文章,评审abstract::Alien limb syndrome following stroke within the territory of the posterior cerebral artery is exceedingly rare. A right-handed female experienced left homonymous hemianopia, visuospatial neglect, and proprioceptive loss of her left hemi-body. She experienced unintended, involuntary movements of her left arm and hand, ...
journal_title:Journal of neurology
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journal_title:Journal of neurology
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pub_type: 杂志文章,多中心研究
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pub_type: 杂志文章
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